Augmentation Of Brain Function Facts Fiction And Controversy
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Augmentation of Brain Function: Facts, Fiction and Controversy by Ioan Opris,Manuel F. Casanova,Mikhail Lebedev Pdf
The Volume II is entitled “Neurostimulation and pharmacological approaches”. This volume describes augmentation approaches, where improvements in brain functions are achieved by modulation of brain circuits with electrical or optical stimulation, or pharmacological agents. Activation of brain circuits with electrical currents is a conventional approach that includes such methods as (i) intracortical microstimulation (ICMS), (ii) transcranial direct current stimulation (tDCS), and (iii) transcranial magnetic stimulation (TMS). tDCS and TMS are often regarded as noninvasive methods. Yet, they may induce long-lasting plastic changes in the brain. This is why some authors consider the term “noninvasive” misleading when used to describe these and other techniques, such as stimulation with transcranial lasers. The volume further discusses the potential of neurostimulation as a research tool in the studies of perception, cognition and behavior. Additionally, a notion is expressed that brain augmentation with stimulation cannot be described as a net zero sum proposition, where brain resources are reallocated in such a way that gains in one function are balanced by costs elsewhere. In recent years, optogenetic methods have received an increased attention, and several articles in Volume II cover different aspects of this technique. While new optogenetic methods are being developed, the classical electrical stimulation has already been utilized in many clinically relevant applications, like the vestibular implant and tactile neuroprosthesis that utilizes ICMS. As a peculiar usage of neurostimulation and pharmacological methods, Volume II includes several articles on augmented memory. Memory prostheses are a popular recent development in the stimulation-based BMIs. For example, in a hippocampal memory prosthesis, memory content is extracted from hippocampal activity using a multiple-input, multiple-output non-linear dynamical model. As to the pharmacological approaches to augmenting memory and cognition, the pros and cons of using nootropic drugs are discussed.
Augmentation of Brain Function: Facts, Fiction and Controversy by Mikhail Lebedev,Ioan Opris,Manuel F. Casanova Pdf
Volume I, entitled “Augmentation of Brain Functions: Brain-Machine Interfaces”, is a collection of articles on neuroprosthetic technologies that utilize brain-machine interfaces (BMIs). BMIs strive to augment the brain by linking neural activity, recorded invasively or noninvasively, to external devices, such as arm prostheses, exoskeletons that enable bipedal walking, means of communication and technologies that augment attention. In addition to many practical applications, BMIs provide useful research tools for basic science. Several articles cover challenges and controversies in this rapidly developing field, such as ways to improve information transfer rate. BMIs can be applied to the awake state of the brain and to the sleep state, as well. BMIs can augment action planning and decision making. Importantly, BMI operations evoke brain plasticity, which can have long-lasting effects. Advanced neural decoding algorithms that utilize optimal feedback controllers are key to the BMI performance. BMI approach can be combined with the other augmentation methods; such systems are called hybrid BMIs. Overall, it appears that BMI will lead to many powerful and practical brain-augmenting technologies in the future.
Augmentation of Brain Function: Facts, Fiction and Controversy by Manuel F. Casanova,Mikhail Lebedev,Ioan Opris Pdf
The final volume in this tripartite series on Brain Augmentation is entitled “From Clinical Applications to Ethical Issues and Futuristic Ideas”. Many of the articles within this volume deal with translational efforts taking the results of experiments on laboratory animals and applying them to humans. In many cases, these interventions are intended to help people with disabilities in such a way so as to either restore or extend brain function. Traditionally, therapies in brain augmentation have included electrical and pharmacological techniques. In contrast, some of the techniques discussed in this volume add specificity by targeting select neural populations. This approach opens the door to where and how to promote the best interventions. Along the way, results have empowered the medical profession by expanding their understanding of brain function. Articles in this volume relate novel clinical solutions for a host of neurological and psychiatric conditions such as stroke, Parkinson’s disease, Huntington’s disease, epilepsy, dementia, Alzheimer’s disease, autism spectrum disorders (ASD), traumatic brain injury, and disorders of consciousness. In disease, symptoms and signs denote a departure from normal function. Brain augmentation has now been used to target both the core symptoms that provide specificity in the diagnosis of a disease, as well as other constitutional symptoms that may greatly handicap the individual. The volume provides a report on the use of repetitive transcranial magnetic stimulation (rTMS) in ASD with reported improvements of core deficits (i.e., executive functions). TMS in this regard departs from the present-day trend towards symptomatic treatment that leaves unaltered the root cause of the condition. In diseases, such as schizophrenia, brain augmentation approaches hold promise to avoid lengthy pharmacological interventions that are usually riddled with side effects or those with limiting returns as in the case of Parkinson’s disease. Brain stimulation can also be used to treat auditory verbal hallucination, visuospatial (hemispatial) neglect, and pain in patients suffering from multiple sclerosis. The brain acts as a telecommunication transceiver wherein different bandwidth of frequencies (brainwave oscillations) transmit information. Their baseline levels correlate with certain behavioral states. The proper integration of brain oscillations provides for the phenomenon of binding and central coherence. Brain augmentation may foster the normalization of brain oscillations in nervous system disorders. These techniques hold the promise of being applied remotely (under the supervision of medical personnel), thus overcoming the obstacle of travel in order to obtain healthcare. At present, traditional thinking would argue the possibility of synergism among different modalities of brain augmentation as a way of increasing their overall effectiveness and improving therapeutic selectivity. Thinking outside of the box would also provide for the implementation of brain-to-brain interfaces where techniques, proper to artificial intelligence, could allow us to surpass the limits of natural selection or enable communications between several individual brains sharing memories, or even a global brain capable of self-organization. Not all brains are created equal. Brain stimulation studies suggest large individual variability in response that may affect overall recovery/treatment, or modify desired effects of a given intervention. The subject’s age, gender, hormonal levels may affect an individual’s cortical excitability. In addition, this volume discusses the role of social interactions in the operations of augmenting technologies. Finally, augmenting methods could be applied to modulate consciousness, even though its neural mechanisms are poorly understood. Finally, this volume should be taken as a debate on social, moral and ethical issues on neurotechnologies. Brain enhancement may transform the individual into someone or something else. These techniques bypass the usual routes of accommodation to environmental exigencies that exalted our personal fortitude: learning, exercising, and diet. This will allow humans to preselect desired characteristics and realize consequent rewards without having to overcome adversity through more laborious means. The concern is that humans may be playing God, and the possibility of an expanding gap in social equity where brain enhancements may be selectively available to the wealthier individuals. These issues are discussed by a number of articles in this volume. Also discussed are the relationship between the diminishment and enhancement following the application of brain-augmenting technologies, the problem of “mind control” with BMI technologies, free will the duty to use cognitive enhancers in high-responsibility professions, determining the population of people in need of brain enhancement, informed public policy, cognitive biases, and the hype caused by the development of brain- augmenting approaches.
Augmentation of Brain Function: Facts, Fiction and Controversy. Volume III: From Clinical Applications to Ethical Issues and Futuristic Ideas by Anonim Pdf
The final volume in this tripartite series on Brain Augmentation is entitled "From Clinical Applications to Ethical Issues and Futuristic Ideas". Many of the articles within this volume deal with translational efforts taking the results of experiments on laboratory animals and applying them to humans. In many cases, these interventions are intended to help people with disabilities in such a way so as to either restore or extend brain function. Traditionally, therapies in brain augmentation have included electrical and pharmacological techniques. In contrast, some of the techniques discussed in this volume add specificity by targeting select neural populations. This approach opens the door to where and how to promote the best interventions. Along the way, results have empowered the medical profession by expanding their understanding of brain function. Articles in this volume relate novel clinical solutions for a host of neurological and psychiatric conditions such as stroke, Parkinson's disease, Huntington's disease, epilepsy, dementia, Alzheimer's disease, autism spectrum disorders (ASD), traumatic brain injury, and disorders of consciousness. In disease, symptoms and signs denote a departure from normal function. Brain augmentation has now been used to target both the core symptoms that provide specificity in the diagnosis of a disease, as well as other constitutional symptoms that may greatly handicap the individual. The volume provides a report on the use of repetitive transcranial magnetic stimulation (rTMS) in ASD with reported improvements of core deficits (i.e., executive functions). TMS in this regard departs from the present-day trend towards symptomatic treatment that leaves unaltered the root cause of the condition. In diseases, such as schizophrenia, brain augmentation approaches hold promise to avoid lengthy pharmacological interventions that are usually riddled with side effects or those with limiting returns as in the case of Parkinson's disease. Brain stimulation can also be used to treat auditory verbal hallucination, visuospatial (hemispatial) neglect, and pain in patients suffering from multiple sclerosis. The brain acts as a telecommunication transceiver wherein different bandwidth of frequencies (brainwave oscillations) transmit information. Their baseline levels correlate with certain behavioral states. The proper integration of brain oscillations provides for the phenomenon of binding and central coherence. Brain augmentation may foster the normalization of brain oscillations in nervous system disorders. These techniques hold the promise of being applied remotely (under the supervision of medical personnel), thus overcoming the obstacle of travel in order to obtain healthcare. At present, traditional thinking would argue the possibility of synergism among different modalities of brain augmentation as a way of increasing their overall effectiveness and improving therapeutic selectivity. Thinking outside of the box would also provide for the implementation of brain-to-brain interfaces where techniques, proper to artificial intelligence, could allow us to surpass the limits of natural selection or enable communications between several individual brains sharing memories, or even a global brain capable of self-organization. Not all brains are created equal. Brain stimulation studies suggest large individual variability in response that may affect overall recovery/treatment, or modify desired effects of a given intervention. The subject's age, gender, hormonal levels may affect an individual's cortical excitability. In addition, this volume discusses the role of social interactions in the operations of augmenting technologies. Finally, augmenting methods could be applied to modulate consciousness, even though its neural mechanisms are poorly understood. Finally, this volume should be taken as a debate on social, moral and ethical issues on neurotechnologies. Brain enhancement may transform the individual into someone or something else. These techniques bypass the usual routes of accommodation to environmental exigencies that exalted our personal fortitude: learning, exercising, and diet. This will allow humans to preselect desired characteristics and realize consequent rewards without having to overcome adversity through more laborious means. The concern is that humans may be playing God, and the possibility of an expanding gap in social equity where brain enhancements may be selectively available to the wealthier individuals. These issues are discussed by a number of articles in this volume. Also discussed are the relationship between the diminishment and enhancement following the application of brain-augmenting technologies, the problem of "mind control" with BMI technologies, free will the duty to use cognitive enhancers in high-responsibility professions, determining the population of people in need of brain enhancement, informed public policy, cognitive biases, and the hype caused by the development of brain- augmenting approaches.
Augmentation of Brain Function: Facts, Fiction and Controversy. Volume I: Brain-Machine Interfaces by Anonim Pdf
Volume I, entitled "Augmentation of Brain Functions: Brain-Machine Interfaces", is a collection of articles on neuroprosthetic technologies that utilize brain-machine interfaces (BMIs). BMIs strive to augment the brain by linking neural activity, recorded invasively or noninvasively, to external devices, such as arm prostheses, exoskeletons that enable bipedal walking, means of communication and technologies that augment attention. In addition to many practical applications, BMIs provide useful research tools for basic science. Several articles cover challenges and controversies in this rapidly developing field, such as ways to improve information transfer rate. BMIs can be applied to the awake state of the brain and to the sleep state, as well. BMIs can augment action planning and decision making. Importantly, BMI operations evoke brain plasticity, which can have long-lasting effects. Advanced neural decoding algorithms that utilize optimal feedback controllers are key to the BMI performance. BMI approach can be combined with the other augmentation methods; such systems are called hybrid BMIs. Overall, it appears that BMI will lead to many powerful and practical brain-augmenting technologies in the future.
Augmentation of Brain Function: Facts, Fiction and Controversy. Volume II: Neurostimulation and Pharmacological Approaches by Anonim Pdf
The Volume II is entitled "Neurostimulation and pharmacological approaches". This volume describes augmentation approaches, where improvements in brain functions are achieved by modulation of brain circuits with electrical or optical stimulation, or pharmacological agents. Activation of brain circuits with electrical currents is a conventional approach that includes such methods as (i) intracortical microstimulation (ICMS), (ii) transcranial direct current stimulation (tDCS), and (iii) transcranial magnetic stimulation (TMS). tDCS and TMS are often regarded as noninvasive methods. Yet, they may induce long-lasting plastic changes in the brain. This is why some authors consider the term "noninvasive" misleading when used to describe these and other techniques, such as stimulation with transcranial lasers. The volume further discusses the potential of neurostimulation as a research tool in the studies of perception, cognition and behavior. Additionally, a notion is expressed that brain augmentation with stimulation cannot be described as a net zero sum proposition, where brain resources are reallocated in such a way that gains in one function are balanced by costs elsewhere. In recent years, optogenetic methods have received an increased attention, and several articles in Volume II cover different aspects of this technique. While new optogenetic methods are being developed, the classical electrical stimulation has already been utilized in many clinically relevant applications, like the vestibular implant and tactile neuroprosthesis that utilizes ICMS. As a peculiar usage of neurostimulation and pharmacological methods, Volume II includes several articles on augmented memory. Memory prostheses are a popular recent development in the stimulation-based BMIs. For example, in a hippocampal memory prosthesis, memory content is extracted from hippocampal activity using a multiple-input, multiple-output non-linear dynamical model. As to the pharmacological approaches to augmenting memory and cognition, the pros and cons of using nootropic drugs are discussed.
Modern Approaches to Augmentation of Brain Function by Ioan Opris,Mikhail A. Lebedev,Manuel F. Casanova Pdf
This book covers recent advances in neural technology that provide for enhancements for brain function. It addresses a broad range of neural phenomena occurring in the brain circuits involved in perception, cognition, emotion and action, that represent the building blocks of behavior and cognition. Augmentation of brain function can be achieved by using brain implants for recordings, stimulation, or drug delivery. Alternative methods include employing brain-machine interfaces, as well as noninvasive activation of certain brain areas. This volume evaluates existing methods of brain augmentation while discussing the brain circuitry and neuronal mechanisms that make augmentation possible. This volume offers novel insights into brain disorders, and explores new devices for brain repair while also addressing the philosophical and ethical implications of brain augmentation. The information in this book is relevant to researchers in the fields of neuroscience, engineering, and clinical practice. Advance Praise for Modern Approaches to Augmentation of Brain Function: “This impressive book by leading experts in neuroscience and neuroengineering lays out the future of brain augmentation, in which the human mind and machine merge, leading to a rapid exponential growth of the power of humanity.” Ray Kurzweil, best-selling author, inventor, entrepreneur and a recipient of the National Medal of Technology and Innovation (1999), and the Lemelson-MIT Prize (2001) "This book employs a holistic approach in covering the recent advances in the fields of neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology. Each chapter of the book covers major aspects of modern brain research in connection with the human mind and behavior, and is authored by researchers with unique expertise in their field. " Ioan Dumitrache, Prof. Dr. Eng. Faculty of Computer Science, Polytechnic University of Bucharest, Bucharest, Romania “This book presents compelling perspectives on what interactive neuroscience will look like in the future, delving into the innovatory ideas of a diverse set of neuroscientists, and speculating on the different ways computer chips implanted in the brains of humans can effect intelligence and communication.” György Buzsáki, MD, PhD is the Biggs Professor of Neuroscience, NYU School of Medicine, New York, NY
Brain Function Augmentation: Contemporary Clinical Neuroscience by Benjamin Green Pdf
The central nervous system of the human body is made up of the brain and the spinal cord. The brain is responsible for receiving and processing the information from the sense organs, taking decisions accordingly and sending directions to the rest of the body. There are various areas of the brain, each with a specialized function. The augmentation of brain functions involves enhancing the performance of the brain in healthy adults as well as people suffering from neurological disorders. Sensory, cognitive and motor functions are the three main areas which are targeted by this field. This augmentation can be done either through neurostimulation or through pharmacological means. This book includes some of the vital pieces of work being conducted across the world, on various topics related to brain functions. It presents researches and studies performed by experts across the globe. Scientists and students actively engaged in this field will find this book full of crucial and unexplored concepts.
Modern Approaches to Augmentation of Brain Function by Ioan Opris,Mikhail A. Lebedev,Manuel F. Casanova Pdf
This book covers recent advances in the neural technology that produces enhancements for brain function. It addresses a broad range of neural phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the behavior and mind. Augmentation of brain function is achieved using brain implants for recordings, stimulation and drug delivery. Alternative methods include employing brain-machine interfaces, as well as noninvasive activation of certain brain areas. Existing methods of brain augmentation are evaluated, and new approaches are introduced. Brain circuitry and neuronal mechanisms that are candidates for augmentation are discussed. This volume provides novel insights into brain disorders, and new devices for brain repair. Information in this book is relevant to researchers in the field of neuroscience, engineering, and clinical practice. Philosophical and ethical implications of brain augmentation are also addressed. "This impressive book by leading experts in neuroscience and neuroengineering lays out the future of brain augmentation, in which the human mind and machine merge, leading to a rapid exponential growth of the power of humanity." - Ray Kurzweil "This book employs a holistic approach in covering the recent advances in the fields of neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology. Each chapter of the book covers major aspects of modern brain research in connection with the human mind and behavior, and is authored by researchers with unique expertise in their field. " - Ioan Dumitrache "This book presents compelling perspectives on what interactive neuroscience will look like in the future, delving into the innovatory ideas of a diverse set of neuroscientists, and speculating on the different ways computer chips implanted in the brains of humans can effect intelligence and communication." - György Buzsáki.
Current Research in Brain Function Augmentation by Max White Pdf
The human brain is a part of the human nervous system. This organ is responsible for controlling almost all the activities of the body. The augmentation of the brain refers to the different ways in which the performance of the brain can be boosted. It can also be used to repair the brain of a person who suffers from a neurological disease. This can be done through a variety of methods such as through brain implants, brain-machine interfaces (BMI), or through pharmacological or electrical stimulation. There are also non-invasive techniques which can activate specific areas of the brain. This book unfolds the innovative aspects of brain augmentation which will be crucial for the progress of this field in the future. The recent studies that are constantly contributing towards advancing technologies and evolution of this field are examined in detail. As this field is emerging at a rapid pace, the contents of this book will help the readers understand the modern concepts and applications of the subject.
The fourth edition of this popular text has been significantly rewritten to make it more accessible to students and easier for instructors to use. It remains distinctive in presenting a unified narrative of cognitive science as a field of inquiry in its own right. Thematically organized, Cognitive Science underscores the problems and solutions of cognitive science rather than more narrowly examining individually the subjects that contribute to it - psychology, neuroscience, linguistics, and so on. The generous use of examples, illustrations, and applications demonstrates how theory and experiment can be applied to unlock the mysteries of the human mind. Drawing upon cutting-edge research, the text has been updated and enhanced with a new chapter on emotions and the emerging field of affective science. An extensive online set of resources is available to aid both instructors and students.
Clinical Aspects of Brain Function Augmentation by Benjamin Green Pdf
The brain is an organ which consists of a mass of nerve tissue which is surrounded by the skull. Its major divisions are cerebrum, cerebellum and brain stem. The cerebrum is divided into two hemispheres, which are further divided into lobes. It is responsible for problem solving, coordinating motor skills, attention, interpreting sensory information, interpreting emotions, etc. The cerebellum helps in the management of fine motor skills as well as helping the body maintain its balance and posture. The functions of the brain can be broadly categorized into sensory information processing, maintaining breathing and blood pressure, and regulating the release of hormones. The book aims to shed light on some of the unexplored aspects of brain functions and the recent researches in this field. Its extensive content provides the readers with a thorough understanding of the subject. This book will prove to be immensely beneficial to students and researchers in this field.
Internet of Things for Human-Centered Design by Sofia Scataglini,Silvia Imbesi,Gonçalo Marques Pdf
The book presents the state of the art of the Internet of Things (IoT), applied to Human-Centered Design (HCD) projects addressed to ageing users, from the perspective of health, care and well-being. The current focus on the ageing population is opening up new opportunities for the development of niche solutions aimed at the niche category of older users who are beginning to experience physical and cognitive decline but are still independent and need to maintain their autonomy for as long as possible. The combination between the needs expressed by older users and the opportunities offered by the recent innovative technologies related to the Internet of Things allows research institutions, stakeholders, and academia to target and design new solutions for older users, safeguarding their well-being, health, and care, improving their quality of life. This book discusses and analyses the most recent services, products, systems and environments specifically conceived for older users, in order to enhance health, care, well-being and improve their quality of life. This approach is coherent with the percept of AAL or enhanced living environment, looking to the users’ comfort, autonomy, engagement and healthcare. The book describes and analyses aspects of HCD with older users looking to the emerging technologies, products, services, and environments analysed in their actual application in different areas, always concerning the design for the elderly related to the IoT, just as the development of biomonitoring devices, tools for activity recognition and simulation, creation of smart living environments, solutions for their autonomy, assistance and engagement enhancing health, care and wellbeing. The book is intended for researchers, designers, engineers, and practitioners in healthcare to connect academia, stakeholders, and research institutions to foster education, research and innovation.
Policy, Identity, and Neurotechnology by Veljko Dubljević,Allen Coin Pdf
In this volume the authors explore the landscape of thought on the ethical and policy implications of Brain Computer Interface (BCI) technology. BCI technology is a promising and rapidly advancing research area. Recent developments in the technology, based on animal and human studies, allow for the restoration and potential augmentation of faculties of perception and physical movement, and even the transfer of information between brains. Brain activity can be interpreted through both invasive and non-invasive monitoring devices, allowing for novel, therapeutic solutions for individuals with disabilities and for other non-medical applications. However, a number of ethical and policy issues have been identified from the use of BCI technology, with the potential for near-future advancements in the technology to raise unique new ethical and policy questions that society has never grappled with before. The volume has three parts: 1) Past, Present and Future of BCI technology, 2) Ethical and Philosophical Issues and 3) Legal and Policy Implications. The rich and detailed picture of the field of BCI ethics with contributors from various fields and backgrounds, from academia and from the commercial sphere may serve as an introductory textbook into the neuroethics of BCI, or as a resource for neuroscientists, engineers, and medical practitioners to gain additional insight into the ethical and policy implications of their work.
This book covers recent advances in the use of electrostimulation therapies in movement disorders, epilepsy, inflammatory bowel disease, memory and cognition, disorders of consciousness, foot drop, dysphagia, brain injury, headache, heart failure, hearing loss, and rheumatoid arthritis. It describes techniques such as vagus nerve stimulation, deep brain stimulation, and electrical stimulation of the pharyngeal nerve. Electroceuticals: Advances in Electrostimulation Therapies is aimed at clinicians and basic researchers in the fields of neurology, neurosurgery, cardiology and rheumatology.
