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The Autoimmune Diseases by Noel R. Rose,Ian R. Mackay Pdf
The Autoimmune Diseases comprehensively describes the clinical expressions of all known autoimmune diseases, as well as the experimental bases of autoimmunity and failure of tolerance. The scientific chapters include mechanisms of natural tolerance, the genetic basis of autoimmunity, the significance of apoptosis, the influence of cytokines, environmental influences, and experimental models. The clinical chapters cover autoimmune endocrine deficiencies, insulin-dependent diabetes, rheumatic disorders, neurological diseases, and diseases of the blood, skin, eye, kidney, and liver.
Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
The Autoimmune Diseases by Noel R. Rose,Ian R. Mackay Pdf
The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P’s" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments. The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment. Gives a thorough and important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and its therapy Provides thorough, up-to-date information on specific diseases, along with clinical applications in an easily found reference for clinicians and researchers interested in certain diseases Keeps readers abreast of current trends and emerging areas in the field Ensures that content is not only up-to-date, but applicable and relevant Includes new, updated chapters that emphasize hot topics in the field, e.g., research on auto inflammatory diseases and autoimmune responses following cancer immunotherapy
Treating Autoimmune Disease with Chinese Medicine by Wanzhu Hou,Guangpi Xu,Hanjie Wang Pdf
This book clearly describes how Chinese medicine can treat autoimmune diseases. Recommendations are given for acupuncture and herbal treatments for patients with a variety of different symptoms, blood results, and medical histories.
Idiotypes in Medicine: Autoimmunity, Infection and Cancer by R.C. Kennedy,S. Ferrone,Yehuda Shoenfeld Pdf
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.
Women, Work, and Autoimmune Disease by Joan Friedlander,Rosalind Joffe, MEd Pdf
Women, Work, and Autoimmune Disease is a book for women who live with chronic illness, encouraging them to stay employed to preserve their independence and sense of self. Rich with information and inspiration, it is the voice of warmth, wisdom, understanding, and compassion. Filled with tips, tricks and first-person accounts from women who have made similar choices in their own lives, this unique book is a resounding call for self-reliance and resilience. The book identifies the factors that making working particularly difficult for women with autoimmune disease, and then offers practical suggestions to address them. The authors take a hard, yet inspirational look at what it takes be successful in a job, including developing strategies and tactics, evaluating communication skills, building a support team and considerations for self-employment. Women, Work, and Autoimmune Disease covers issues such as: The complex nature of autoimmune disease The correlation between disease, diagnosis, and career development How life-changing strategies and concrete tactics can allow you to discover the spirit within
B Cell Receptor Signaling by Tomohiro Kurosaki,Jürgen Wienands Pdf
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Autoimmune Diseases by Munther A Khamashta,Manuel Ramos-Casals Pdf
Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex management. These include abdominal pain, arthritis, cutaneous ulcers, gastrointestinal hemorrhage, epilepsy, pancreatitis, stroke and white-matter CNS lesions. Autoimmune Diseases: Acute and Complex Situations addresses the latest clinical and immunological prognostic factors that may help to identify patients at higher risk of developing potentially life-threatening involvement. This book comprehensively helps the reader to diagnose these patients, in whom an early therapeutic approach is essential. Autoimmune Diseases: Acute and Complex Situations is a valuable reference tool for rheumatologists, internists, immunologists, and all the specialists involved in the multidisciplinary care of patient with rheumatic and systemic autoimmune diseases.
Diagnostic Criteria in Autoimmune Diseases by Yehuda Shoenfeld,Ricard Cervera,M. Eric Gershwin Pdf
According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.
A page-turning and powerful medical mystery for readers of Diagnosis by Lisa Sanders and The Beauty in Breaking by Michele Harper More than 20 million Americans have autoimmune diseases, which occur when the immune system attacks the body. Autoimmune diseases are often misdiagnosed by doctors and overlooked by medical researchers. Almost all affect women more often than men. The Immune Mystery follows doctor and researcher Anita Kåss’s quest to solve the autoimmune puzzle, beginning with the premature death of her mother, who developed rheumatoid arthritis shortly after giving birth to Anita. As a child, Anita vowed to study the illness and one day find a cure. Becoming a respected doctor and researcher, Anita devoted herself to studying auto-immune disorders like rheumatoid arthritis, lupus, and multiple sclerosis. Why do so many autoimmune diseases start to show symptoms during and after childbirth, perimenopause, and menopause? Could autoimmune diseases be linked to our changing hormones? Despite the groundbreaking nature of her research, Anita had to fight for her ideas against the conventional wisdom and casual sexism of the medical industry––even as she made a discovery that earned her a record-breaking US$95 million pharmaceutical deal. A compelling blend of incredible determination and cutting-edge science, The Immune Mystery changes the way we think about autoimmune diseases. Anita offers solace to patients struggling with questions about their health, and introduces a powerful new voice in medical storytelling.
Autoimmune Disease Models by Irun R. Cohen,Ariel Miller Pdf
Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.
An Epidemic of Absence by Moises Velasquez-Manoff Pdf
A controversial, revisionist approach to autoimmune and allergic disorders considers the perspective that the human immune system has been disabled by twentieth-century hygiene and medical practices.
Autoimmune Diseases of the Skin by Michael Hertl Pdf
Autoimmune disorders of the skin remain an enigma for many clinicians and scientists not familiar with these mostly severe and chronic diseases. The book provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs. The third edition has been thoroughly updated and extended by chapters on paraneoplastic cutaneous syndromes, atopic dermatitis and autoimmunity and Skin manifestations of rheumatic diseases.
Author : Ian R. Mackay,Noel R Rose Publisher : Academic Press Page : 1304 pages File Size : 42,6 Mb Release : 2013-12-03 Category : Medical ISBN : 9780123849304
The Autoimmune Diseases by Ian R. Mackay,Noel R Rose Pdf
Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors. Gives a thorough and an important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and therapy Provides thorough, up-to-date information on specific diseases, along with clinical applications, in an easily found reference for clinicians and researchers interested in certain diseases Keeps readers abreast of current trends and emerging areas in the field Ensures that content is not only up-to-date, but applicable and relevant
Autoimmune Diseases and Diagnostic Approaches by Kenan Demir,Selim Görgün Pdf
The collection of essays reviews, explores, and reports state-of-the-art autoimmune diseases and their diagnostics. It provides a comprehensive presentation of autoimmune diseases, diagnostic approaches with current trends, and possible developments in health sciences. As such, it is a unique resource for medical educators, medical practitioners, and academics.