Bacterial Membrane Vesicles

Author : Maria Kaparakis-Liaskos,Thomas A. Kufer
Publisher : Springer Nature
Page : 258 pages
File Size : 52,6 Mb
Release : 2020-03-31
Category : Science
ISBN : 9783030363314

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Bacterial Membrane Vesicles by Maria Kaparakis-Liaskos,Thomas A. Kufer Pdf

This book focuses on the multitude of functions bacterial membrane vesicles perform in bacterial ecology and pathogenesis as well as in emerging medical and biotechnological applications. Both Gram-negative and Gram-positive bacteria produce membrane-bound nanostructures, known as membrane vesicles, which have a range of functions that include serving as delivery vehicles, providing a means of communication over both spatial and temporal scales, and contributing to bacterial survival and evolution. Topics covered in this book range from the biogenesis and composition of bacterial membrane vesicles to their abundance and biological roles in microbial ecosystems, such as marine environments. In the individual chapters, the involvement of bacterial membrane vesicles in host-pathogen interactions, promoting virulence and in facilitating the establishment of infection is explained. In addition, current knowledge regarding membrane vesicles produced by commensal bacteria and their role in the maturation of the host immune system, as well as the therapeutic potential of bacterial membrane vesicles as delivery systems and innovative nanotechnology-based therapeutics are discussed. This work appeals to a wide readership of students and researchers interested in microbial ecology, mechanism underlying pathogenesis and new avenues in applied microbiology and nanotechnology.

Author : Anonim
Publisher : Unknown
Page : 258 pages
File Size : 55,6 Mb
Release : 2020
Category : Bacterial cell walls
ISBN : 3030363325

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Bacterial Membrane Vesicles by Anonim Pdf

This book focuses on the multitude of functions bacterial membrane vesicles perform in bacterial ecology and pathogenesis as well as in emerging medical and biotechnological applications. Both Gram-negative and Gram-positive bacteria produce membrane-bound nanostructures, known as membrane vesicles, which have a range of functions that include serving as delivery vehicles, providing a means of communication over both spatial and temporal scales, and contributing to bacterial survival and evolution. Topics covered in this book range from the biogenesis and composition of bacterial membrane vesicles to their abundance and biological roles in microbial ecosystems, such as marine environments. In the individual chapters, the involvement of bacterial membrane vesicles in host-pathogen interactions, promoting virulence and in facilitating the establishment of infection is explained. In addition, current knowledge regarding membrane vesicles produced by commensal bacteria and their role in the maturation of the host immune system, as well as the therapeutic potential of bacterial membrane vesicles as delivery systems and innovative nanotechnology-based therapeutics are discussed. This work appeals to a wide readership of students and researchers interested in microbial ecology, mechanism underlying pathogenesis and new avenues in applied microbiology and nanotechnology.

Author : S.N. Chatterjee,Keya Chaudhuri
Publisher : Springer Science & Business Media
Page : 161 pages
File Size : 41,8 Mb
Release : 2012-08-01
Category : Medical
ISBN : 9783642305269

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Outer Membrane Vesicles of Bacteria by S.N. Chatterjee,Keya Chaudhuri Pdf

This book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of different pathogenic and non-pathogenic Gram-negative bacteria. It also includes an authentic record of the first systematic study that discovered the mechanism of OMV formation by a pathogen, Vibrio cholerae, and proposed that the process represented a novel secretory activity of bacteria. Furthermore, the authors present clinical and laboratory data on the use of OMVs as immunogens, as effective and licensed vaccines against Neisseria meningitidis serogroup B infections and on the development of more effective vaccines against other human and animal pathogens including Vibrio cholerae. This volume thus bears witness to the emerging revolution in the field of vaccines against pathogens and closes with a discussion of open questions and future research on OMVs.

Author : Araceli Contreras-Rodriguez,Rafael A. Garduno,Alejandro J. Yañez
Publisher : Frontiers Media SA
Page : 259 pages
File Size : 45,9 Mb
Release : 2022-08-19
Category : Science
ISBN : 9782889768004

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What Is known and What Remains To Be Discovered About Bacterial Outer Membrane Vesicles by Araceli Contreras-Rodriguez,Rafael A. Garduno,Alejandro J. Yañez Pdf

Author : Araceli Contreras-Rodriguez,Rafael A. Garduno,Alejandro J. Yañez
Publisher : Frontiers Media SA
Page : 121 pages
File Size : 49,7 Mb
Release : 2022-11-11
Category : Science
ISBN : 9782832505250

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What is known and What Remains to Be Discovered About Bacterial Outer Membrane Vesicles, Volume II by Araceli Contreras-Rodriguez,Rafael A. Garduno,Alejandro J. Yañez Pdf

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 674 pages
File Size : 49,8 Mb
Release : 2018-04-16
Category : Science
ISBN : 9780128136881

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Lipid Nanocarriers for Drug Targeting by Alexandru Mihai Grumezescu Pdf

Lipid Nanocarriers for Drug Targeting presents recent advances in the area of lipid nanocarriers. The book focuses on cationic lipid nanocarriers, solid lipid nanocarriers, liposomes, thermosensitive vesicles, and cubosomes, with applications in phototherapy, cosmetic and others. As the first book related to lipid nanocarriers and their direct implication in pharmaceutical nanotechnology, this important reference resource is ideal for biomaterials scientists and those working in the medical and pharmaceutical industries that want to learn more on how lipids can be used to create more effective drug delivery systems. Highlights the most commonly used types of lipid nanocarriers and explains how they are applied in pharmacy Shows how lipid nanocarriers are used in different types of treatment, including oral medicine, skin repair and cancer treatment Assesses the pros and cons of using different lipid nanocarriers for different therapies

Author : Anton Ficai,Alexandru Mihai Grumezescu
Publisher : Elsevier
Page : 722 pages
File Size : 52,9 Mb
Release : 2017-05-29
Category : Medical
ISBN : 9780323461511

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Nanostructures for Antimicrobial Therapy by Anton Ficai,Alexandru Mihai Grumezescu Pdf

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 51,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Anthony Martonosi
Publisher : Springer Science & Business Media
Page : 461 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468426588

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The Enzymes of Biological Membranes by Anthony Martonosi Pdf

Much of the information currently available on the transport systems of bacterial and animal cell membranes and their mode of coupling to metabolic supply of energy can be found in this volume. Consideration of the participating enzymes dictated the choice of topics: Several transport systems where little information is available on the enzymology of the process are not included, while separate chapters deal with y-glutamyl transpeptidase and intestinal disaccharidases which meet many of the requirements of transport enzymes. The volume also includes two chapters on photosynthetic membranes as a general introduction to the topic. Other aspects of biological transport and photosynthesis will be developed in detail in a forthcoming volume now in preparation. These chapters reveal the excitement and rapid advance of the field, the daily reports of new concepts, new techniques, and new experimental findings which instantly interact to generate further progress. Our aim was to provide a starting point for those who are just beginning, and an opportunity for others to stop, take stock, and start in a new direction. My warmest thanks to all who contributed to this volume.

Author : Jos A.F. Op den Kamp
Publisher : Springer Science & Business Media
Page : 474 pages
File Size : 40,7 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642731846

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Membrane Biogenesis by Jos A.F. Op den Kamp Pdf

Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Author : Loretta Leive
Publisher : Unknown
Page : 520 pages
File Size : 46,9 Mb
Release : 1973
Category : Science
ISBN : MINN:31951P007443967

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Bacterial Membranes and Walls by Loretta Leive Pdf

Author : Maria Sandkvist,Eric Cascales,Peter J. Christie
Publisher : John Wiley & Sons
Page : 128 pages
File Size : 55,5 Mb
Release : 2020-07-02
Category : Science
ISBN : 9781683670285

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Protein Secretion in Bacteria by Maria Sandkvist,Eric Cascales,Peter J. Christie Pdf

Protein transport into and across membranes is a fundamental process in bacteria that touches upon and unites many areas of microbiology, including bacterial cell physiology, adhesion and motility, nutrient scavenging, intrabacterial signaling and social behavior, toxin deployment, interbacterial antagonism and collaboration, host invasion and disruption, and immune evasion. A broad repertoire of mechanisms and macromolecular machines are required to deliver protein substrates across bacterial cell membranes for intended effects. Some machines are common to most, if not all bacteria, whereas others are specific to Gram-negative or Gram-positive species or species with unique cell envelope properties such as members of Actinobacteria and Spirochetes. Protein Secretion in Bacteria, authored and edited by an international team of experts, draws together the many distinct functions and mechanisms involved in protein translocation in one concise tome. This comprehensive book presents updated information on all aspects of bacterial protein secretion encompassing: Individual secretory systems–Sec, Tat, and T1SS through the newly discovered T9SS Mechanisms, structures, and functions of bacterial secretion systems Lipoprotein sorting pathways, outer membrane vesicles, and the sortase system Structures and roles of surface organelles, including flagella, pili, and curli Emerging technologies and translational implications Protein Secretion in Bacteria serves as both an introductory guide for students and postdocs and a ready reference for seasoned researchers whose work touches on protein export and secretion. This volume synthesizes the diversity of mechanisms of bacterial secretion across the microbial world into a digestible resource to stimulate new research, inspire continued identification and characterization of novel systems, and bring about new ways to manipulate these systems for biotechnological, preventative, and therapeutic applications.

Author : Véronique Arluison,Claudio Valverde
Publisher : Humana Press
Page : 395 pages
File Size : 42,7 Mb
Release : 2018-02-27
Category : Medical
ISBN : 1493976338

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Bacterial Regulatory RNA by Véronique Arluison,Claudio Valverde Pdf

This volume details the most important methods used for studying prokaryotic non-coding RNAs and their protein accomplices. Chapters present methods in sections covering different aspects of the biology of that field: identification of ncRNAs, their differential expression, characterization of their structure, abundance, intracellular location and function, their interaction with RNA binding proteins, and plausible applications of ncRNA elements in the rapidly emerging field of synthetic biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacterial Regulatory RNA: Methods and Protocols serves as a guidebook for scientists working toward the development of new tools and procedures for the vital field of sRNA biology.

Author : Rumiana Dimova,Carlos Marques
Publisher : CRC Press
Page : 1144 pages
File Size : 47,6 Mb
Release : 2019-11-19
Category : Science
ISBN : 9781351648554

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The Giant Vesicle Book by Rumiana Dimova,Carlos Marques Pdf

Giant vesicles are widely used as a model membrane system, both for basic biological systems and for their promising applications in the development of smart materials and cell mimetics, as well as in driving new technologies in synthetic biology and for the cosmetics and pharmaceutical industry. The reader is guided to use giant vesicles, from the formation of simple membrane platforms to advanced membrane and cell system models. It also includes fundamentals for understanding lipid or polymer membrane structure, properties and behavior. Every chapter includes ideas for further applications and discussions on the implications of the observed phenomena towards understanding membrane-related processes. The Giant Vesicle Book is meant to be a road companion, a trusted guide for those making their first steps in this field as well as a source of information required by experts. Key Features • A complete summary of the field, covering fundamental concepts, practical methods, core theory, and the most promising applications • A start-up package of theoretical and experimental information for newcomers in the field • Extensive protocols for establishing the required preparations and assays • Tips and instructions for carefully performing and interpreting measurements with giant vesicles or for observing them, including pitfalls • Approaches developed for investigating giant vesicles as well as brief overviews of previous studies implementing the described techniques • Handy tables with data and structures for ready reference

Author : National Research Council,Division on Engineering and Physical Sciences,Space Studies Board,Commission on Physical Sciences, Mathematics, and Applications,Steering Group for the Workshop on Size Limits of Very Small Microorganisms
Publisher : National Academies Press
Page : 164 pages
File Size : 46,7 Mb
Release : 1999-09-13
Category : Science
ISBN : 0309172748

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Size Limits of Very Small Microorganisms by National Research Council,Division on Engineering and Physical Sciences,Space Studies Board,Commission on Physical Sciences, Mathematics, and Applications,Steering Group for the Workshop on Size Limits of Very Small Microorganisms Pdf

How small can a free-living organism be? On the surface, this question is straightforward-in principle, the smallest cells can be identified and measured. But understanding what factors determine this lower limit, and addressing the host of other questions that follow on from this knowledge, require a fundamental understanding of the chemistry and ecology of cellular life. The recent report of evidence for life in a martian meteorite and the prospect of searching for biological signatures in intelligently chosen samples from Mars and elsewhere bring a new immediacy to such questions. How do we recognize the morphological or chemical remnants of life in rocks deposited 4 billion years ago on another planet? Are the empirical limits on cell size identified by observation on Earth applicable to life wherever it may occur, or is minimum size a function of the particular chemistry of an individual planetary surface? These questions formed the focus of a workshop on the size limits of very small organisms, organized by the Steering .Group for the Workshop on Size Limits of Very Small Microorganisms and held on October 22 and 23, 1998. Eighteen invited panelists, representing fields ranging from cell biology and molecular genetics to paleontology and mineralogy, joined with an almost equal number of other participants in a wide-ranging exploration of minimum cell size and the challenge of interpreting micro- and nano-scale features of sedimentary rocks found on Earth or elsewhere in the solar system. This document contains the proceedings of that workshop. It includes position papers presented by the individual panelists, arranged by panel, along with a summary, for each of the four sessions, of extensive roundtable discussions that involved the panelists as well as other workshop participants.