Beyond The Borders The Gates And Fences Of Neuroimmune Interaction

Author : Javier Velázquez-Moctezuma,Emilio Domínguez-Salazar,Beatriz Gómez-González
Publisher : Frontiers E-books
Page : 120 pages
File Size : 42,7 Mb
Release : 2014-10-10
Category : Electronic book
ISBN : 9782889192748

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Beyond the borders: The gates and fences of Neuroimmune interaction by Javier Velázquez-Moctezuma,Emilio Domínguez-Salazar,Beatriz Gómez-González Pdf

Neuroimmunology is a rapidly growing emerging field at which two old sciences have converged to integrate two different types of responses into a single coherent response involving the coordinated action of both systems, neural and immune. During long time it was thought that both systems worked separately and in divergent pathways. The brain was considered an immunoprivileged site and the immune organs were deemed as independent of any neural influence and also of nervous innervation. Time has gone and has proven that the borders between both systems were merely artificial. Since the beginning of Neuroimmunology in the 1980s much work has been done to elucidate the gates and fences in neuro-immune interactions. Brain was shown to be under the continuous surveillance of the immune system, even under basal physiological conditions in the absence of any pathology. Likely, it was found a profuse nervous innervation of lymphoid organs and even of single immune cells. Gates for direct neural immune communication were found both centrally and peripherally. Centrally, the gates, but also the fences, were situated at the brain barriers, the blood-brain barrier and the blood-cerebrospinal fluid barrier, and at the circunventricular organs. Peripherally, the fences constituted the apparent diverse nature of molecules involved in neural and immune signaling; however, time proved that both system were capable of producing the same signaling molecules and also systematically responded to the molecules released by the other system. Therefore, the gates were open for direct neural-immune communication at the peripheral level. This Research Topic aimed to include original reports, reviews and technical reports regarding the description of the gates and fences in neural immune interactions. We intended to provide an extensive view of the mechanisms governing central and peripheral neural-immune interactions, and the role of the borders, the blood-neural barriers, in the regulation of the neural-immune communication.

Author : Michael J. Parnham,Frans P. Nijkamp,Adriano G. Rossi
Publisher : Springer Nature
Page : 888 pages
File Size : 43,6 Mb
Release : 2019-12-10
Category : Medical
ISBN : 9783030108113

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Nijkamp and Parnham's Principles of Immunopharmacology by Michael J. Parnham,Frans P. Nijkamp,Adriano G. Rossi Pdf

Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.

Author : Kristian Bjørkdahl,Alex C. Parrish
Publisher : Lexington Books
Page : 319 pages
File Size : 41,9 Mb
Release : 2017-11-30
Category : Literary Criticism
ISBN : 9781498558464

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Rhetorical Animals by Kristian Bjørkdahl,Alex C. Parrish Pdf

For this edited volume, the editors solicited chapters that investigate the place of nonhuman animals in the purview of rhetorical theory; what it would mean to communicate beyond the human community; how rhetoric reveals our "brute roots." In other words, this book investigates themes that enlighten us about likely or possible implications of the animal turn within rhetorical studies. The present book is unique in its focus on the call for nonanthropocentrism in rhetorical studies. Although there have been many hints in recent years that rhetoric is beginning to consider the implications of the animal turn, as yet no other anthology makes this its explicit starting point and sustained objective. Thus, the various contributions to this book promise to further the ongoing debate about what rhetoric might be after it sheds its long-standing humanistic bias.

Author : Parvin Mehdipour
Publisher : Springer
Page : 1170 pages
File Size : 53,7 Mb
Release : 2017-09-20
Category : Medical
ISBN : 9783319645506

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Cancer Genetics and Psychotherapy by Parvin Mehdipour Pdf

The aim of this book is to provide the readers with the most comprehensive and latest accounts of research and development in this field by emphasizing on the manner of relation between doctors and cancer patients in direction of improving the patients’ style of life. This book, partly, will deal with psychotherapy by considering cancer patients, benefits, hazards and also social impacts including life style. The social supports as the key and influential paradigms will be challenged as a comparative insight by considering the global unity in order to provide a reasonable model to improve the interaction between cancer and psychological nest. In this book, the real stories of cancer patient will be also provided. The initial insight of sections includes: 1) Brief classifications and key points of clinical and histopatological aspects of each organ. 2) Brief view of genetic alterations in each organ. 3) Therapeutic aspects. 4) Brief classifications and key points of Psychology in cancer. 5) The interactions of clinical aspects with psychological field.

Author : Orlagh Farrell Delaney
Publisher : Cambridge Scholars Publishing
Page : 277 pages
File Size : 49,7 Mb
Release : 2021-07-30
Category : Body, Mind & Spirit
ISBN : 9781527573284

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An Evocative Autoethnography of Living Alongside Myalgic Encephalomyelitis (ME) by Orlagh Farrell Delaney Pdf

This ground-breaking book explores and explains the day-to-day realities of living long-term with Myalgic Encephalomyelitis (ME). ME is an acquired complex disorder characterised by a variety of symptoms affecting multiple systems of the body. Marked fatigue and weakness, sickness, cognitive dysfunction and symptom flare-up can follow any physical or cognitive exertion. It is estimated that there are 17-24 million sufferers worldwide. The author has lived with moderately severe ME for the last 18 years. Utilising autoethnography as a methodology and drawing on multidisciplinary social science theory, the book tells the story of the author’s own lived experiences of the illness, and how she sought to reimagine a ‘self’ or a life living alongside the illness, that could still be considered a ‘good life’. This autoethnographic book is beautifully and evocatively written. It is a work of scholarship that will be highly accessible to academic and other readers. It is also a comprehensive introduction to autoethnography as a methodology, but it is much more. The images and poetry complement the narrative discussion, and are exemplary as part of an approach that integrates creative work with academic argument. It illuminates the struggles of living with ME and how there can be sanctuary.

Author : Mette S. Herskin,Jens Malmkvist
Publisher : BRILL
Page : 243 pages
File Size : 52,5 Mb
Release : 2023-09-04
Category : Technology & Engineering
ISBN : 9789086868582

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Proceedings of the 51st Congress of the International Society for Applied Ethology by Mette S. Herskin,Jens Malmkvist Pdf

Understanding animal behaviour is the overall theme of this 51st Congress of the International Society for Applied Ethology and the red thread through the chosen scientific topics. Understanding animal behaviour is essential in order to improve the interaction between animals and the environments in which they are kept and to improve animal welfare. The abstracts in this proceedings book give an overview of the scientific topics discussed at the conference. The world of animals: senses and perception Human-animal interactions Animal learning and cognition Animal stress responses Social behaviour of animals Applying ethology in the keeping of animals Animal affective states Maternal and neonatal behaviour

Author : SANTIRAM KAL
Publisher : PHI Learning Pvt. Ltd.
Page : 602 pages
File Size : 54,9 Mb
Release : 2009-01-14
Category : Technology & Engineering
ISBN : 8120319524

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BASIC ELECTRONICS by SANTIRAM KAL Pdf

This comprehensive and well-organized text discusses the fundamentals of electronic communication, such as devices and analog and digital circuits, which are so essential for an understanding of digital electronics. Professor Santiram Kal, with his wealth of knowledge and his years of teaching experience, compresses, within the covers of a single volume, all the aspects of electronics - both analog and digital - encompassing devices such as microprocessors, microcontrollers, fibre optics, and photonics. In so doing, he has struck a fine balance between analog and digital electronics. A distinguishing feature of the book is that it gives case studies in modern applications of electronics, including information technology, that is, DBMS, multimedia, computer networks, Internet, and optical communication. Worked-out examples, interspersed throughout the text, and the large number of diagrams should enable the student to have a better grasp of the subject. Besides, exercises, given at the end of each chapter, will sharpen the student's mind in self-study. These student-friendly features are intended to enhance the value of the text and make it both useful and interesting.

Author : Günther Witzany
Publisher : Springer Science & Business Media
Page : 432 pages
File Size : 40,7 Mb
Release : 2012-11-13
Category : Science
ISBN : 9789400748996

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Viruses: Essential Agents of Life by Günther Witzany Pdf

A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.

Author : Massimo Loda,Lorelei A. Mucci,Megan L. Mittelstadt,Mieke Van Hemelrijck,Maura Bríd Cotter
Publisher : Springer
Page : 670 pages
File Size : 51,7 Mb
Release : 2016-09-01
Category : Medical
ISBN : 9783319351537

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Pathology and Epidemiology of Cancer by Massimo Loda,Lorelei A. Mucci,Megan L. Mittelstadt,Mieke Van Hemelrijck,Maura Bríd Cotter Pdf

This book integrates the disciplines of cancer pathology and epidemiology to provide a synergistic and complementary approach to understanding the molecular mechanisms of cancer. This book provides relevant information on the diagnostic, prognostic and predictive molecular pathology of cancer. Epidemiological studies, including descriptive epidemiology, risk factors and molecular mechanisms of disease inform on the etiology and progression of cancer. The text concentrates on major cancers that are currently prevalent and those for which substantial molecular, pathological and epidemiological data is available. Each section is designed to provide an overview of that cancer type in terms of basic biology, review the current epidemiological data surrounding that cancer type and provide information on common practices and challenges related to the molecular pathology of that cancer type. Several relevant techniques in molecular pathology, which facilitate diagnosis and treatment are also explored. Pathology and Epidemiology of Cancer provides a succinct and comprehensive overview of multiple cancer types to guide clinicians during patient care and to guide scientists for innovations in research. It represents an integral resource for pathologists, epidemiologists, medical students as well as translational, basic and clinical science researchers who are all working to progress the field of cancer in terms of diagnosis, treatment and prevention.

Author : Menizibeya Osain Welcome
Publisher : Springer
Page : 1028 pages
File Size : 50,7 Mb
Release : 2018-06-20
Category : Medical
ISBN : 9783319910567

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Gastrointestinal Physiology by Menizibeya Osain Welcome Pdf

This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers’ understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special “clinical correlates” sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.

Author : International Society for Animal Hygiene
Publisher : Unknown
Page : 1451 pages
File Size : 52,5 Mb
Release : 2011
Category : Electronic
ISBN : 8026300084

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XV ISAH Congress 2011 by International Society for Animal Hygiene Pdf

Author : Robert A. McCleery,Christopher E. Moorman,M. Nils Peterson
Publisher : Springer
Page : 406 pages
File Size : 49,6 Mb
Release : 2014-11-11
Category : Science
ISBN : 9781489975003

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Urban Wildlife Conservation by Robert A. McCleery,Christopher E. Moorman,M. Nils Peterson Pdf

In the past, wildlife living in urban areas were ignored by wildlife professionals and urban planners because cities were perceived as places for people and not for wild animals. Paradoxically, though, many species of wildlife thrive in these built environments. Interactions between humans and wildlife are more frequent in urban areas than any other place on earth and these interactions impact human health, safety and welfare in both positive and negative ways. Although urban wildlife control pest species, pollinate plants and are fun to watch, they also damage property, spread disease and even attack people and pets. In urban areas, the combination of dense human populations, buildings, impermeable surfaces, introduced vegetation, and high concentrations of food, water and pollution alter wildlife populations and communities in ways unseen in more natural environments. For these ecological and practical reasons, researchers and mangers have shown a growing interest in urban wildlife ecology and management. This growing interest in urban wildlife has inspired many studies on the subject that have yet to be synthesized in a cohesive narrative. Urban Wildlife: Theory and Practice fills this void by synthesizing the latest ecological and social knowledge in the subject area into an interdisciplinary and practical text. This volume provides a foundation for the future growth and understanding of urban wildlife ecology and management by: • Clearly defining th e concepts used to study and describe urban wildlife, • Offering a cohesive understanding of the coupled natural and social drivers that shape urban wildlife ecology, • Presenting the patterns and processes of wildlife response to an urbanizing world and explaining the mechanisms behind them and • Proposing means to create physical and social environments that are mutually beneficial for both humans and wildlife.

Author : William R. Tiffany,James A. Carrell
Publisher : McGraw-Hill Humanities, Social Sciences & World Languages
Page : 456 pages
File Size : 40,9 Mb
Release : 1977
Category : Language Arts & Disciplines
ISBN : IND:30000007209210

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Phonetics, Theory and Application by William R. Tiffany,James A. Carrell Pdf

Author : Alfred Binet
Publisher : Unknown
Page : 152 pages
File Size : 40,8 Mb
Release : 1889
Category : Science
ISBN : HARVARD:HW2OVR

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The Psychic Life of Micro-organisms by Alfred Binet Pdf

Author : Lynn Margulis,Dorion Sagan
Publisher : Chelsea Green Publishing
Page : 282 pages
File Size : 47,5 Mb
Release : 2007-08-15
Category : Science
ISBN : 9781603581363

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Dazzle Gradually by Lynn Margulis,Dorion Sagan Pdf

At the crossroads of philosophy and science, the sometimes-dry topics of evolution and ecology come alive in this new collection of essays--many never before anthologized. Learn how technology may be a sort of second nature, how the systemic human fungus Candida albicans can lead to cravings for carrot cake and beer, how the presence of life may be why there's water on Earth, and many other fascinating facts. The essay "Metametazoa" presents perspectives on biology in a philosophical context, demonstrating how the intellectual librarian, pornographer, and political agitator Georges Bataille was influenced by Russian mineralogist Vladimir Vernadsky and how this led to his notion of the absence of meaning in the face of the sun--which later influenced Jacques Derrida, thereby establishing a causal chain of influence from the hard sciences to topics as abstract as deconstruction and post-modernism. In "Spirochetes Awake" the bizarre connection between syphilis and genius in the life of Friedrich Nietzsche is traced. The astonishing similarities of the Acquired-Immune-Deficiency-Syndrome symptoms with those of chronic spirochete infection, it is argued, contrast sharply with the lack of evidence that "HIV is the cause of AIDS". Throughout these readings we are dazzled by the intimacy and necessity of relationships between us and our other planetmates. In our ignorance as "civilized" people we dismiss, disdain, and deny our kinship with the only productive life forms that sustain this living planet.