Binding Cultures

Author : Gay Wilentz
Publisher : Indiana University Press
Page : 180 pages
File Size : 52,6 Mb
Release : 1992-05-22
Category : History
ISBN : 0253207142

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Binding Cultures by Gay Wilentz Pdf

"Wilentz . . . makes convincing arguments for the connections between African and Afro-American women's culture." —Nellie McKay "Wilentz's jargon-free, intelligent discussion . . . will appeal to students in African, African American, and women's literature courses, as well as general readers interested in the emerging field." —Choice "Through these works, Wilentz demonstrates the powerful transformation possible through understanding—and embracing—the past, even if that past includes oppression and brutalization." —Belles Lettres Binding Cultures investigates the cultural bonds between African and African-American women writers such as Nigerian Flora Nwapa and Ghanaians Efua Sutherland and Ama Ata Aidoo, writers who focus on the role of women in passing on cultural values to future generations, and African-American writers Alice Walker, Toni Morrison, and Paule Marshall, who self-consciously evoke African culture to help create a more integrated African-American community.

Author : James W. Carey
Publisher : Routledge
Page : 402 pages
File Size : 46,5 Mb
Release : 2008-10-22
Category : Language Arts & Disciplines
ISBN : 9781135857028

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Communication as Culture, Revised Edition by James W. Carey Pdf

In this classic text, James W. Carey maintains that communication is not merely the transmission of information; reminding the reader of the link between the words "communication" and "community," he broadens his definition to include the drawing-together of a people that is culture. In this context, Carey questions the American tradition of focusing only on mass communication's function as a means of social and political control, and makes a case for examining the content of a communication—the meaning of symbols, not only the motives that originate them or the purposes they serve. He seeks to recast the goal of communication studies, replacing the search for deterministic laws of behavior with a simpler, yet far more challenging mission: "to enlarge the human conversation by comprehending what others are saying." This new edition includes a new critical foreword by G. Stuart Adam that explains Carey's fundamental role in transforming the study of mass communication to include a cultural perspective and connects his classic essays with contemporary media issues and trends. This edition also adds a new, complete bibliography of all of Carey's writings.

Author : Michael D. P. Boyle
Publisher : Academic Press
Page : 494 pages
File Size : 40,9 Mb
Release : 2014-05-10
Category : Health & Fitness
ISBN : 9781483216539

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Bacterial Immunoglobulin–Binding Proteins by Michael D. P. Boyle Pdf

Bacterial Immunoglobulin-Binding Proteins: Applications in Immunotechnology, Volume 2 covers the state of knowledge of bacterial immunoglobulin-binding proteins. The book focuses on practical approaches to isolation, characterization, and use of bacterial immunoglobulin-binding proteins. The majority of these studies involve the type I Fc-binding protein (staphylococcal protein A) and the type III Fc-binding protein (streptococcal protein G). Physiological chemists, pediatricians, and microbiologists will find the book invaluable.

Author : H. Edward Conrad
Publisher : Elsevier
Page : 553 pages
File Size : 52,5 Mb
Release : 1997-10-02
Category : Medical
ISBN : 9780080533902

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Heparin-Binding Proteins by H. Edward Conrad Pdf

This book describes the complex structures of heparins and heparan sulfates (heparinoids) and how they are generated by their biosynthetic pathways. The book also details the methodologies for studying these structures and their cellular metabolism. Heparin-Binding Proteins introduces the general nature of interactions between heparinoids and proteins, and presents the role for these structures in their interactions with the proteins of the hemostatic mechanisms, fibroblasts growth factors, superoxide dismutase, and lipoproteins. Covers cellular metabolism of heparinoid proteoglycans Written by a distinguished expert in the field of carbohydrate biochemistry Describes the roles of heparan sulfate proteoglycans in Blood coagulation and fibrinolysis Lipoprotein metabolism Superoxide dismutase activity Fibroblast growth factor responses of cells

Author : John Middlebrook
Publisher : Elsevier
Page : 389 pages
File Size : 55,5 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323141338

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Receptor-Mediated Binding and Internalization of Toxins and Hormones by John Middlebrook Pdf

Receptor-Mediated Binding and Internalization of Toxins and Hormones presents the proceedings of a conference conducted for the purpose of exploring relationships between hormones and toxins, specifically, receptor-mediated internalization of toxins and hormones and the role of this internalization in message transmission and biodegradatory processes. This book is divided into three sections, with the first focusing on model systems of internalization. It presents pictorial illustrations of the receptor-mediated endocytosis of low-density lipoprotein via coated regions of membrane and discusses the receptor for lysosomal enzymes on the surface of cultured fibroblasts. The second section focuses on toxins and hormones and discusses such topics as receptor-mediated internalization of diphtheria toxin, diphtheria toxin interactions with an inhibitory activity from plasma membranes, and uptake mechanisms for ADP-ribosylating toxins. The third and final section focuses on hybrids and discusses such topics as chimeric toxins containing fragment A from diphtheria toxin, directed entry of hybrid proteins into cells via alternate receptors, and a hybrid protein of monoclonal anti-THY 1.2 and diphtheria toxin fragment A. This book will be of interest to practitioners in the fields of endocrinology, cell biology, and molecular genetics.

Author : Anonim
Publisher : Unknown
Page : 1132 pages
File Size : 40,6 Mb
Release : 2024-06-17
Category : Environmental health
ISBN : UCR:31210007568759

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Environmental Health Perspectives by Anonim Pdf

Author : Andreas Hoeflich,John Pintar,Briony Forbes
Publisher : Frontiers Media SA
Page : 148 pages
File Size : 49,8 Mb
Release : 2019-02-06
Category : Electronic
ISBN : 9782889457182

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Current Perspectives on Insulin-like Growth Factor Binding Protein (IGFBP) Research by Andreas Hoeflich,John Pintar,Briony Forbes Pdf

The family of IGFBPs has been developed by the duplication of genes and genomes and contributes to genetic and functional diversity. Due to the different protein domains present in the molecule, IGFBPs can be seen as mediators of tissue-specific IGF-functions. However, IGFBPs also have IGF-independent functions both inside and outside the cell. These diverse genetic, molecular and functional aspects of IGFBPs are discussed within this Research Topic. Accumulating data provide evidence for the regulation of IGFBP-functions by proteases, which may acutely regulate bioactivity of the IGFs. However, during proteolytic degradation IGFBP-fragments with novel functions can also be formed and are located both intra- and extracellularly. Distinct IGFBP-fragments can even be found in the perinuclear compartment or within the nucleus, where they can impact on gene expression. Several contributions presented in the current Research Topic particularly stress the relevance of structural aspects in IGFBP research. The current lack of comprehensive structural information is dramatically limiting the biomarker potential of particular IGFBPs. Finally, the Research Topic also provides novel functions of the IGFBP family from model organisms, farm animals and humans. Thereby, the biomarker potential not only relates to normal and malignant growth but also to metabolism and animal welfare. One important aim of the Research Topic is to encourage next generation IGFBP research reflecting subject-individual, conditional, and hormonal parameters but also structural aspects of the IGFBPs.

Author : Guido Ruggiero
Publisher : Oxford University Press
Page : 297 pages
File Size : 51,7 Mb
Release : 1993-06-10
Category : History
ISBN : 9780195359442

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Binding Passions by Guido Ruggiero Pdf

Mining the rich Venetian archives, especially the unusually detailed records of Venice's own branch of the Roman Inquisition, Guido Ruggiero provides a strikingly new and provocative interpretation of the end of the Renaissance in Italy. In this boldly structured work, he develops five narrative accounts of individual encounters with the Inquisition that illustrate the double-edged metaphor of how passions were both bound by late Renaissance society and were seen in turn as binding people. In this way new perspectives are opened on magic, witchcraft, love, marriage, gender, and discipline at the level of the community and beyond. Witches, courtesans, prostitutes, women healers, nobles, Cardinals, and renegade priests and monks speak from these pages describing their lives, beliefs, hopes, fears, and lies. With an imaginative flair for storytelling and impeccable scholarship, Ruggiero exposes the rich complexity of the culture and poetics of the everyday at the end of the Renaissance and illuminates a previously unexplored chapter in Italian history.

Author : J.M. Polak
Publisher : Birkhäuser
Page : 419 pages
File Size : 54,5 Mb
Release : 2013-03-07
Category : Science
ISBN : 9783034891363

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Regulatory Peptides by J.M. Polak Pdf

J. M. Polak and S. R. Bloom For some time Experientia has published, as a unique feature, interdis ciplinary multi-author reviews, giving a comprehensive overview of sub jects regarded as 'growing edges' of science. The enthusiasm shown by the readers was contagious and thus it was felt necessary to compile a special volume dealing with the novel aspects of regulatory peptides. This book covers some of the growing areas in regulatory peptide research and, although it is based on the original volume of Experientia, it is expanded and updated. The topic of 'regulatory peptides' is relatively young and has grown at an unprecedented pace, from the embryonic conception of 'gut hor mones' or 'brain neuropeptides' some 15 years ago to the realisation that these active pep tides are found, almost without exception, in every part of l8 23 the body in all vertebrate and many invertebrate species • Why the term 'regulatory peptides'? It represents a convenient label encompassing both the active peptides present in nerves, which are re leased as (putative) neurotransmitters, and those in endocrine cells, which act locally or at a distance as circulating hormones, these being the l8 main components of the so-called diffuse neuroendocrine or APUD 17 system • Morphological studies support this physiological viewpoint.

Author : Alessandro Bausi,Michael Friedrich
Publisher : Walter de Gruyter GmbH & Co KG
Page : 396 pages
File Size : 54,7 Mb
Release : 2023-08-07
Category : Language Arts & Disciplines
ISBN : 9783111292069

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Tied and Bound: a Comparative View on Manuscript Binding by Alessandro Bausi,Michael Friedrich Pdf

The present volume contains twelve chapters authored by specialists of Asian, African and European manuscript cultures reflecting on the cohesion of written artefacts, particularly manuscripts. Assuming that 'codicological units' exist in every manuscript culture and that they are usually composed of discrete elements (such as clay tablets, papyrus sheets, bamboo slips, parchment bifolios, palm leaves), the issue of the cohesion of the constituents is a general one. The volume presents a series of case studies on devices and strategies adopted to achieve this cohesion by manuscript cultures distant in space (from China to West Africa) and time (from the third millennium bce to the present). This comparative view provides the frame for the understanding of a phenomenon that appears to be of essential importance for the study of the structure of written artefacts. Regardless of the way in which cohesion is realised, all strategies and devices that allow the constituents to be kept together are subsumed under the term 'binding'. Thus, it is possible to highlight similarities, convergences, and unique physical and technical methods adopted by various manuscript cultures to face a common challenge.

Author : Michael D.P. Boyle
Publisher : Academic Press
Page : 430 pages
File Size : 41,5 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323140584

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Bacterial Immunoglobulin-binding Proteins V1 by Michael D.P. Boyle Pdf

Bacterial Immunoglobulin-Binding Proteins, Volume 1: Microbiology, Chemistry, and Biology investigates the immunoglobulin and Fc-binding proteins that have been isolated and characterized from a wide array of microorganisms, including protein A from staphylococcus and protein G from streptococcus. It examines the antigenic relationships among bacterial immunoglobulin-binding proteins, the immunoglobulin D-binding bacteria, the complement activation and bacterial immunoglobulin-binding proteins, the nature of the interaction of bacterial Fc receptors and immunoglobulin G, and the bacterial Fc receptors as putative virulence factors. Organized into 31 chapters, this volume begins with a historical overview of bacterial immunoglobulin-binding proteins, receptors for immunoglobulins, amino acid sequence of Fc receptors, and cloning of genes. It then discusses the staphylococcal protein A, including its biological activities and applications to immunotechnology. The book also explains the gene for staphylococcal protein A, immunoglobulin G Fc receptors of group A streptococci, and streptococcal protein G. It presents the structure and evolution of the streptococcal genes encoding protein G and interaction of bacterial immunoglobulin receptors with sites in the Fab region. It also discusses the lymphocyte stimulation by bacterial Fc receptors and cloning and expression of the beta protein gene of group B streptococci. The book concludes with a chapter on Fc receptors and the pathogenesis of bacterial infections in animals. This book will be of interest to biologists, microbiologists, chemists, and researchers working with immunoglobulin-binding proteins found in bacteria.

Author : Michael R. Kreutz,José R. Naranjo,Karl-Wilhelm Koch,Beat Schwaller
Publisher : Frontiers Media SA
Page : 214 pages
File Size : 55,8 Mb
Release : 2016-11-01
Category : Electronic book
ISBN : 9782889450039

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The Neuronal Functions of EF-hand Ca(2+)-binding Proteins 2nd Edition by Michael R. Kreutz,José R. Naranjo,Karl-Wilhelm Koch,Beat Schwaller Pdf

Ca2+ signaling in neurons is characterized by highly restricted and dynamic gradients called Ca2+ waves, spikes, transients and puffs depending upon their corresponding spatial and temporal features. Based on this strict segmentation the Ca2+ ion provides a versatile basis for complex signaling in neuronal subcompartments with a spatial resolution of micro- and nanodomains. The multitude of Ca2+-regulated processes requires specialized downstream processing machinery, translating the Ca2+ signal into alterations of cellular processes. The broad range of different Ca2+-triggered phenomena in neurons, ranging from neurotransmission to gene expression, is reflected by the existence of a multitude of different Ca2+-binding proteins (CaBPs) from which numerous belong to the EF-hand super-family. EF-hand proteins can be subdivided into Ca2+ buffer and Ca2+ sensor proteins. Whereas the first group has a very high affinity for Ca2+, exhibits little conformational change in the Ca2+-bound state and is thought to mainly chelate Ca2+, the second group has a lower affinity for Ca2+ and shows considerable conformational changes upon Ca2+-binding, which usually triggers a target interaction. Neuronal calcium sensor (NCS) proteins and the related Caldendrin/CaBP/Calneuron (nCaBPs) proteins are members of this latter group. They resemble the structure of their common ancestor Calmodulin (CaM) with four EF-hand Ca2+-binding motifs, of which not all are functional. However, despite their structural homology with CaM, NCS as well as nCaBPs are quite diverse in amino acid sequence. It is therefore surprising that relatively few binding partners have been identified that are not CaM targets and this raises the question of the specificity and function of these interactions. In terms of function, binding of NCS and nCaBP has frequently different consequences than binding of CaM, which substantially increases the versatility of the Ca2+ tool kit. The general idea of this special issue is to provide an overview on the function of neuronal EF-hand calcium-binding proteins in health and disease. But we will not just provide a mere collection of articles to stress the function of each protein. The issue will mainly deal with emerging concepts on Ca2+-signaling/buffering mediated by EF-hand Ca2+-binding proteins. This includes questions like features that define the functional role of a EF-hand calcium sensor in neurons, the conditions that make physiological relevance of a given interaction of a CaBP with its target plausible, the emerging synaptic role of these proteins, and mounting evidence for their role in the regulation of protein trafficking. Structural aspects and biophysical studies will be covered. Another aspect will be the role of CaBPs in brain disease states. This aspect includes studies showing that CaBPs are targets of drugs in clinical use, studies showing that expression levels of calcium-binding proteins are frequently altered in brain disease states as well as reports on mutations in EF-hand calcium sensors linked to human disease.

Author : K. Wirtz
Publisher : Springer Science & Business Media
Page : 387 pages
File Size : 45,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468453355

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Membrane Receptors, Dynamics, and Energetics by K. Wirtz Pdf

Author : Jan F.C. Glatz,Ger J. van der Vusse
Publisher : Springer Science & Business Media
Page : 202 pages
File Size : 43,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461530961

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Cellular Fatty Acid-Binding Proteins II by Jan F.C. Glatz,Ger J. van der Vusse Pdf

Twenty years have elapsed since cytoplasmic proteins exhibiting high-affinity binding of long-chain fatty acids were first identified (Ockner et al., Science 177:56-58, 1972). These cellular fatty acid-binding proteins (FABPs) are now well established to comprise a ligand-defined group of macromolecules belonging to a family of cytoplasmic lipid binding proteins. Unique features of the FABPs are the existence of distinct types of FABP and that these are found in a variety of tissues in remarkable abundance, with some cells expressing more than one type. The physiological significance of the FABPs has only partly been elucidated. By increasing the cytoplasmic solubilization of fatty acids, the cellular FABPs are considered to function primarily in intracellular fatty acid transport, but may also be assigned important regulatory roles in cellular lipid homeostasis as well as in the modulation of cell growth and differentiation. The broad interests in cellular FABPs has led to the organization of the 1st International Workshop on Fatty Acid-Binding Protein, held in Maastricht, the Netherlands, in 1989. Prompted by the success of the first meeting, the 2nd International Workshop on Fatty-Acid-Binding Proteins, which was held again in Maastricht, on August 31 and September 1, 1992, brought together scientific scpecialists in the field of FABP research for two days of intensive and fruitful discussion. This volume is a collection of selected papers from this conference, and thus provides the state-of-the-art knowledge of cellular FABPs. The contributors to this issue represent pioneering as well as new investigators, and also reflect the multidisciplinary nature of research in this exciting and rapidly progressing field.

Author : Heather Bamford
Publisher : University of Toronto Press
Page : 273 pages
File Size : 42,6 Mb
Release : 2018-06-26
Category : History
ISBN : 9781487515270

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Cultures of the Fragment by Heather Bamford Pdf

The majority of medieval and sixteenth-century Iberian manuscripts, whether in Latin, Hebrew, Arabic, Spanish, or Aljamiado (Spanish written in Arabic script), contain fragments or are fragments. The term fragment is used to describe not only isolated bits of manuscript material with a damaged appearance, but also any piece of a larger text that was intended to be a fragment. Investigating the vital role these fragments played in medieval and early modern Iberian manuscript culture, Heather Bamford’s Cultures of the Fragment is focused on fragments from five major Iberian literary traditions, including Hispano-Arabic and Hispano-Hebrew poetry, Latin and Castilian epics, chivalric romances, and the literature of early modern crypto-Muslims. The author argues that while some manuscript fragments came about by accident, many were actually created on purpose and used in a number of ways, from binding materials, to anthology excerpts, and some fragments were even incorporated into sacred objects as messages of good luck. Examining four main motifs of fragmentation, including intention, physical appearance, metonymy, and performance, this work reveals the centrality of the fragment to manuscript studies, highlighting the significance of the fragment to Iberia’s multicultural and multilingual manuscript culture.