Biocatalysis

Biocatalysis Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Biocatalysis book. This book definitely worth reading, it is an incredibly well-written.

Biocatalysis

Peter Grunwald
Biocatalysis Book PDF

Author : Peter Grunwald
Publisher : World Scientific Publishing Company
Page : 1052 pages
File Size : 50,5 Mb
Release : 2009-03-02
Category : Science
ISBN : 9781848168213

Get Book

Biocatalysis by Peter Grunwald Pdf

The book covers the fundamentals of the field of biocatalysis that are not treated in such detail (or even not at all) in existing biocatalysis books or biochemistry textbooks. It of course does not substitute existing biochemistry textbooks but will serve a suitable supplement as it discusses biochemical fundamentals in connection with the respective topics. With focus on the interdisciplinary nature of biocatalysis, the book contains many aspects of fundamental organic chemistry and some of inorganic chemistry as well, which should make it interesting not only for biochemistry but also for chemistry students. An important theme being emphasized in the book is that applied biocatalysis is one of the main prerequisites for a sustainable development. The topics covered ranges from basic enzyme chemistry (biosynthesis, structure, properties, interaction forces, kinetics) to a detailed description of catalytic mechanisms. It covers the fundamentals of the different enzyme classes together with their applications in native and in immobilized state or in the form of whole cells in aqueous as well as non-conventional media. Topics such as catalytic antibodies, nucleic acid catalysts, non-ribosomal peptide synthesis, evolutionary methods, and the design of cells are also included.

Applied Biocatalysis

John Whittall,Peter W. Sutton
Applied Biocatalysis Book PDF

Author : John Whittall,Peter W. Sutton
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 53,9 Mb
Release : 2020-08-21
Category : Science
ISBN : 9781119487036

Get Book

Applied Biocatalysis by John Whittall,Peter W. Sutton Pdf

Provides clear and comprehensive coverage of recently developed applied biocatalysis for synthetic organic chemists with an emphasis to promote green chemistry in pharmaceutical and process chemistry This book aims to make biocatalysis more accessible to both academic and industrial synthetic organic chemists. It focuses on current topics within the applied industrial biocatalysis field and includes short but detailed experimental methods on timely novel biocatalytic transformations using new enzymes or new methodologies using known enzymes. The book also features reactions that are “expanding and making the enzyme toolbox available to chemists”—providing readers with comprehensive methodology and detailed key sourcing information of a wide range of enzymes. Chapters in Applied Biocatalysis: The Chemist’s Enzyme Toolkit are organized by reaction type and feature a short introductory section describing the current state of the art for each example. Much of the book focuses on processes for which the enzymes are readily available so that organic chemists can synthesize appropriate quantities of chemicals with available materials in a standard chemical laboratory. Advanced methods are included to present examples of new enzymes that might encourage collaboration with suppliers or academic groups and that will educate chemists of rapidly expanding future possibilities. Focuses on current topics within the applied industrial biocatalysis field Offers experimental methods on novel biocatalytic transformations using new enzymes or new methodology using known enzymes Covers the hot topics of enzyme and chemoenzymatic cascades and biocatalysis in flow Edited by noted experts from both academia and industry with years of experience in the field of biocatalysis—particularly, the industrial applications of enzymes Written for synthetic organic chemists working in all industries but especially the pharmaceutical industry and for those in academia with an eye for biocatalysis, Applied Biocatalysis: The Chemist’s Enzyme Toolkit will also benefit academic groups in chemistry and related sciences that are using enzymes for synthetic purposes, as well as those working in the area of enzymology and molecular biology.

Biocatalysis

Andreas S. Bommarius,Bettina R. Riebel-Bommarius
Biocatalysis Book PDF

Author : Andreas S. Bommarius,Bettina R. Riebel-Bommarius
Publisher : John Wiley & Sons
Page : 634 pages
File Size : 46,5 Mb
Release : 2007-02-27
Category : Science
ISBN : 9783527606054

Get Book

Biocatalysis by Andreas S. Bommarius,Bettina R. Riebel-Bommarius Pdf

The whole range of biocatalysis, from a firm grounding in theoretical concepts to in-depth coverage of practical applications and future perspectives. The book not only covers reactions, products and processes with and from biological catalysts, but also the process of designing and improving such biocatalysts. One unique feature is that the fields of chemistry, biology and bioengineering receive equal attention, thus addressing practitioners and students from all three areas.

Biocatalysis

Herfried Griengl
Biocatalysis Book PDF

Author : Herfried Griengl
Publisher : Springer Science & Business Media
Page : 184 pages
File Size : 48,5 Mb
Release : 2013-12-01
Category : Science
ISBN : 9783709163108

Get Book

Biocatalysis by Herfried Griengl Pdf

The book contains in its first part reviews on modelling of enzyme properties in organic solvents, lipase-catalysed synthesis of carboxylic amides, chemoenzymatic synthesis of lipidated peptides and chemoenzymatic transformations in nucleoside chemistry. In the second part contributions on recent developments in biocatalysis are given: lipase and esterase catalysed resolutions, investigations on regio- and stereoselective biocatalytic acylations in steroid side-chains and of substrate- and stereospecificity of Penicillin G amidases, deracemisation for amino acid synthesis, biocatalytic hydrolysis of nitriles, enzymatic and microbial hydroxylation of dienes and alpha-methyl esters, enantioselective sulphoxidations by peroxidases.

Biocatalysis

W.-D. Fessner
Biocatalysis Book PDF

Author : W.-D. Fessner
Publisher : Springer Science & Business Media
Page : 254 pages
File Size : 53,6 Mb
Release : 2003-09-05
Category : Science
ISBN : 9783540681168

Get Book

Biocatalysis by W.-D. Fessner Pdf

Here, leading contributors from the forefront of this exciting technology present authoritative and timely reviews on the state of the art of biocatalysis. They cover the whole spectrum from the discovery of novel enzymes - by modern screening, evolutionary or immunological approaches - through immobilization techniques for technical processes, to their use in the asymmetric synthesis of important target compounds.

Biocatalysis

Gonzalo de Gonzalo,Pablo Domínguez de María
Biocatalysis Book PDF

Author : Gonzalo de Gonzalo,Pablo Domínguez de María
Publisher : Royal Society of Chemistry
Page : 532 pages
File Size : 52,7 Mb
Release : 2017-11-02
Category : Science
ISBN : 9781782626190

Get Book

Biocatalysis by Gonzalo de Gonzalo,Pablo Domínguez de María Pdf

Implementing biocatalytic strategies in an industrial setting is a challenging task, especially when commercial scale necessitates a balance between industrial need and economic viability. With invited contributions from a wide range of chemical and pharmaceutical companies, this book bridges the gap between academia and industry. Contributors discuss current processes, types of biocatalysts and improvements, industrial motivation and the key aspects needed for economic success. Focussing on industry related issues, this book will be a useful tool for future research by both practitioners and academics.

Green Biocatalysis

Ramesh N. Patel
Green Biocatalysis Book PDF

Author : Ramesh N. Patel
Publisher : John Wiley & Sons
Page : 792 pages
File Size : 45,8 Mb
Release : 2016-05-09
Category : Technology & Engineering
ISBN : 9781118822357

Get Book

Green Biocatalysis by Ramesh N. Patel Pdf

Green Biocatalysis presents an exciting green technology that uses mild and safe processes with high regioselectivity and enantioselectivity. Bioprocesses are carried out under ambient temperature and atmospheric pressure in aqueous conditions that do not require any protection and deprotection steps to shorten the synthetic process, offering waste prevention and using renewable resources. Drawing on the knowledge of over 70 internationally renowned experts in the field of biotechnology, Green Biocatalysis discusses a variety of case studies with emphases on process R&D and scale-up of enzymatic processes to catalyze different types of reactions. Random and directed evolution under process conditions to generate novel highly stable and active enzymes is described at length. This book features: A comprehensive review of green bioprocesses and application of enzymes in preparation of key compounds for pharmaceutical, fine chemical, agrochemical, cosmetic, flavor, and fragrance industries using diverse enzymatic reactions Discussion of the development of efficient and stable novel biocatalysts under process conditions by random and directed evolution and their applications for the development of environmentally friendly, efficient, economical, and sustainable green processes to get desired products in high yields and enantiopurity The most recent technological advances in enzymatic and microbial transformations and cuttingedge topics such as directed evolution by gene shuffling and enzyme engineering to improve biocatalysts With over 3000 references and 800 figures, tables, equations, and drawings, Green Biocatalysis is an excellent resource for biochemists, organic chemists, medicinal chemists, chemical engineers, microbiologists, pharmaceutical chemists, and undergraduate and graduate students in the aforementioned disciplines.

Modern Biocatalysis

Gavin Williams,Mélanie Hall
Modern Biocatalysis Book PDF

Author : Gavin Williams,Mélanie Hall
Publisher : Royal Society of Chemistry
Page : 594 pages
File Size : 47,7 Mb
Release : 2018-05-31
Category : Science
ISBN : 9781788014533

Get Book

Modern Biocatalysis by Gavin Williams,Mélanie Hall Pdf

The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.

Marine Enzymes for Biocatalysis

Antonio Trincone
Marine Enzymes for Biocatalysis Book PDF

Author : Antonio Trincone
Publisher : Elsevier
Page : 576 pages
File Size : 46,5 Mb
Release : 2013-09-30
Category : Science
ISBN : 9781908818355

Get Book

Marine Enzymes for Biocatalysis by Antonio Trincone Pdf

Marine bioprospecting is a highly topical subject - in both applied and basic research - but, as yet, the marine ecosystem is a relatively unexplored source of natural bioactive substances with potential therapeutic activity. This book addresses the use of marine enzymes in biocatalysis through a series of chapters from leading scientists within academic and industrial fields. Biocatalytic processes can take advantage of the habitat-related properties of marine enzymes, such as salt tolerance, hyperthermostability, barophilicity, cold adaptivity, and so on, whilst also taking into consideration substrate specificity and affinity. These evolved properties are linked to the metabolic functions of the enzymes and to the ecological aspects of the natural source. New properties can also be discovered at the molecular level of catalysis, particularly concerning the stereochemical characteristics of products. Marine enzymes for biocatalysis initially examines the nature and level of interest in marine biological diversity, and outlines the fundamentals of biocatalysis. It goes on to detail sources of marine enzymes, and to analyse examples from both chemical and stereochemical viewpoints of catalysis, including microbial enzymes and animal or plant sources. The book goes on to explore the future potential of marine bioprospecting in biocatalysis. Compiles studies from leading scientists in a direct and accessible format. Includes practical descriptions of results, adding further details not often covered in formal articles Takes a molecular view which fully explains the enzymatic aspects of reactions, particularly regarding biocatalytic characteristics and descriptions of bioprocesses Selects examples of chemical and stereochemical aspects of enzymatic action with respect to known terrestrial counterparts

Biocatalysis for the Pharmaceutical Industry

Junhua (Alex) Tao,Guo-Qiang Lin,Andreas Liese
Biocatalysis for the Pharmaceutical Industry Book PDF

Author : Junhua (Alex) Tao,Guo-Qiang Lin,Andreas Liese
Publisher : John Wiley & Sons
Page : 250 pages
File Size : 55,8 Mb
Release : 2009-07-23
Category : Science
ISBN : 9780470823156

Get Book

Biocatalysis for the Pharmaceutical Industry by Junhua (Alex) Tao,Guo-Qiang Lin,Andreas Liese Pdf

Biocatalysis is rapidly evolving into a key technology for the discovery and production of chemicals, especially in the pharmaceutical industry, where high yielding chemo-, regio-, and enantioselective reactions are critical. Taking the latest breakthroughs in genomics and proteomics into consideration, Biocatalysis for the Pharmaceutical Industry concisely yet comprehensively discusses the modern application of biocatalysis to drug discovery, development, and manufacturing. Written by a team of leading experts, the book offers deep insight into this cutting edge field. Covers a wide range of topics in a systematic manner with an emphasis on industrial applications Provides a thorough introduction to the latest biocatalysts, modern expression hosts, state-of-the-art directed evolution, high throughput screening, and bioprocess engineering Addresses frontier subjects such as emerging enzymes, metabolite profiling, combinatorial biosynthesis, metabolic engineering, and autonomous enzymes for the synthesis and development of chiral molecules, drug metabolites, and semi-synthetic medicinal compounds and natural product analogs Highlights the impact of biocatalysis on green chemistry Contains numerous graphics to illustrate concepts and techniques Biocatalysis for the Pharmaceutical Industry is an essential resource for scientists, engineers, and R&D policy makers in the fine chemical, pharmaceutical, and biotech industries. It is also an invaluable tool for academic researchers and advanced students of organic and materials synthesis, chemical biology, and medicinal chemistry.

Biocatalysis in Asymmetric Synthesis

Gonzalo De Gonzalo,Andrés R. Alcántara
Biocatalysis in Asymmetric Synthesis Book PDF

Author : Gonzalo De Gonzalo,Andrés R. Alcántara
Publisher : Elsevier
Page : 522 pages
File Size : 52,8 Mb
Release : 2024-05-04
Category : Science
ISBN : 9780443190582

Get Book

Biocatalysis in Asymmetric Synthesis by Gonzalo De Gonzalo,Andrés R. Alcántara Pdf

Biocatalysis in Asymmetric Synthesis, a new volume in the Foundations and Frontiers of Enzymology series, offers an applied discussion of synthesizing biological catalysts using asymmetric synthesis, for applications across research and industry. Here, global experts in the field analyze a wide variety of biocatalysts and their physical states, process conditions for their asymmetric synthesis, solvents required during synthesis, and even downstream procedures for the recovery of final products. The book adopts an interdisciplinary approach, merging fundamental biology and its synthetic applications across industries, with a wide range of practical examples, from directed evolution to biotransformation and production of novel enzymes and non-conventional catalysts. Throughout the book, the impact and application of biocatalysis in sustainable processing is considered in-depth. This book will also help non-experts in biocatalysis to apply this knowledge in their own research, providing a thorough overview of the ways asymmetric biocatalytic approaches may be adapted for different disciplines and downstream products. Explores biocatalysts as exquisite catalysts for fine chiral compound synthesis in different reaction media Features both foundational overviews and applied, practical examples across research and industry Includes chapter contributions from international leaders in the field

Modern Biocatalysis

Wolf-Dieter Fessner,Thorleif Anthonsen
Modern Biocatalysis Book PDF

Author : Wolf-Dieter Fessner,Thorleif Anthonsen
Publisher : John Wiley & Sons
Page : 400 pages
File Size : 53,5 Mb
Release : 2008-12-03
Category : Science
ISBN : 9783527623846

Get Book

Modern Biocatalysis by Wolf-Dieter Fessner,Thorleif Anthonsen Pdf

This reference covers the wide and rapidly growing field of biocatalysis. It combines complementary expertise from such areas as microbiology, enzymology, molecular biology structural biology and organic chemistry, thus highlighting the interdisciplinary nature of the subject. With its special focus on progress and new developments towards environmentally beneficial reactions with high levels of selectivity for the production of key compound classes, this book will enlighten both chemists and biologists as to the advances and opportunities existing in enzyme catalysis.

Pharmaceutical Biocatalysis

Peter Grunwald
Pharmaceutical Biocatalysis Book PDF

Author : Peter Grunwald
Publisher : CRC Press
Page : 863 pages
File Size : 46,5 Mb
Release : 2019-11-07
Category : Business & Economics
ISBN : 9781000707311

Get Book

Pharmaceutical Biocatalysis by Peter Grunwald Pdf

This volume provides an insight into the future strategies for commercial biocatalysis with a focus on sustainable technologies, together with chemoenzymatic and biotechnological approaches to synthesize various types of approved and new active pharmaceutical ingredients (APIs) via proven and latest synthetic routes using single-step biocatalytic or enzyme cascade reactions. Many of these drugs act as enzyme inhibitors, as discussed in a chapter with a variety of examples. The targeted enzymes are involved in diseases such as different cancers, metastatic and infectious diseases, osteoporosis, and cardiovascular disorders. The biocatalysts employed for API synthesis include hydrolytic enzymes, alcohol dehydrogenases, laccases, imine reductases, reductive aminases, peroxygenases, cytochrome P450 enzymes, polyketide synthases, transaminases, and halogenases. Many of them have been improved with respect to their properties by engineering methods. The book discusses the syntheses of drugs, including alkaloids and antibiotics, non-ribosomal peptides, antimalarial and antidiabetic drugs, prenylated xanthones, antioxidants, and many important (chiral) intermediates required for the synthesis of pharmaceuticals.

Practical Methods for Biocatalysis and Biotransformations 2

John Whittall,Peter W. Sutton
Practical Methods for Biocatalysis and Biotransformations 2 Book PDF

Author : John Whittall,Peter W. Sutton
Publisher : John Wiley & Sons
Page : 397 pages
File Size : 51,6 Mb
Release : 2012-04-25
Category : Technology & Engineering
ISBN : 9781118307861

Get Book

Practical Methods for Biocatalysis and Biotransformations 2 by John Whittall,Peter W. Sutton Pdf

Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities. Practical Methods for Biocatalysis and Biotransformations 2 is a "how-to" guide that focuses on the practical applications of enzymes and strains of microorganisms that are readily obtained or derived from culture collections. The sources of starting materials and reagents, hints, tips and safety advice (where appropriate) are given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative methodology are given and relevant references to the primary literature are cited. This second volume – which can be used on its own or in combination with the first volume - concentrates on new applications and new enzyme families reported since the first volume. Contents include: introduction to recent developments and future needs in biocatalysts and synthetic biology in industry reductive amination enoate reductases for reduction of electron deficient alkenes industrial carbonyl reduction regio- and stereo- selective hydroxylation oxidation of alcohols selective oxidation industrial hydrolases and related enzymes transferases for alkylation, glycosylation and phosphorylation C-C bond formation and decarboxylation halogenation/dehalogenation/heteroatom oxidation tandem and sequential multi-enzymatic syntheses Practical Methods for Biocatalysis and Biotransformations 2 is an essential collection of biocatalytic methods for chemical synthesis which will find a place on the bookshelves of synthetic organic chemists, pharmaceutical chemists, and process R&D chemists in industry and academia.

Future Directions in Biocatalysis

Tomoko Matsuda
Future Directions in Biocatalysis Book PDF

Author : Tomoko Matsuda
Publisher : Elsevier
Page : 460 pages
File Size : 54,9 Mb
Release : 2017-08-11
Category : Technology & Engineering
ISBN : 9780444637505

Get Book

Future Directions in Biocatalysis by Tomoko Matsuda Pdf

Future Directions in Biocatalysis, Second Edition, presents the future direction and latest research on how to utilize enzymes, i.e., natural catalysts, to make medicines and other necessities for humans. It emphasizes the most important and unique research on biocatalysis instead of simply detailing the ABC’s on the topic. This book is an indispensable tool for new researchers in the field to help identify specific needs, start new projects that address current environmental concerns, and develop techniques based on green technology. It provides invaluable hints and clues for conducting new research on enzymes, with final sections outlining future directions in biocatalysis further expanding the science into new applications. Gives future directions in the area of biocatalysis research Presents research topics based on their uniqueness, originality, and novelty Includes many explanatory figures to demonstrate concepts to both organic chemists and biochemists Shows that there is no boundary between organic chemistry and biochemistry