Biochemical Oscillations And Cellular Rhythms

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Biochemical Oscillations and Cellular Rhythms

A. Goldbeter
Biochemical Oscillations and Cellular Rhythms Book PDF

Author : A. Goldbeter
Publisher : Cambridge University Press
Page : 632 pages
File Size : 42,7 Mb
Release : 1996-01-26
Category : Science
ISBN : 9780521403078

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Biochemical Oscillations and Cellular Rhythms by A. Goldbeter Pdf

This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. Clarifying the mechanism of these oscillatory phenomena is of key importance for understanding the origin as well as the physiological function of these rhythms, and the conditions in which simple periodic behaviour transforms into complex oscillations, including bursting and chaos. The approach rests on the analysis of theoretical models closely related to experimental observations. Among the main rhythms considered are glycolytic oscillations observed in yeast and muscle, oscillations of cyclic AMP in Dictyostelium amoebae, intracellular calcium oscillations observed in a variety of cell types, the mitotic oscillator that drives the cell division cycle in eukaryotes, and circadian oscillations of the period protein (PER) in Drosophila. For each of these phenomena, experimental facts are reviewed and mathematical models presented.

Biochemical Oscillations and Cellular Rhythms

Albert Goldbeter
Biochemical Oscillations and Cellular Rhythms Book PDF

Author : Albert Goldbeter
Publisher : Cambridge University Press
Page : 632 pages
File Size : 41,8 Mb
Release : 1997-04-03
Category : Science
ISBN : 0521599466

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Biochemical Oscillations and Cellular Rhythms by Albert Goldbeter Pdf

This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. The approach rests on the analysis of theoretical models closely related to experimental observations. Among the main rhythms considered are glycolytic oscillations observed in yeast and muscle, oscillations of cyclic AMP in Dictyostelium amoebae, intracellular calcium oscillation observed in a variety of cell types, the mitotic oscillator that drives the cell division cycle in eukaryotes, pulsatile hormone signaling, and circadian rhythms in Drosophila. This book will be of interest to life scientists such as biochemists, cell biologists, chronobiologists, medical scientists and pharmacologists. In addition, it will appeal to scientists studying nonlinear phenomena, including oscillations and chaos, in chemistry, physics, mathematics and theoretical biology.

Biological Clocks, Rhythms, and Oscillations

Daniel B. Forger
Biological Clocks Rhythms and Oscillations Book PDF

Author : Daniel B. Forger
Publisher : MIT Press
Page : 369 pages
File Size : 51,6 Mb
Release : 2017-11-16
Category : Science
ISBN : 9780262036771

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Biological Clocks, Rhythms, and Oscillations by Daniel B. Forger Pdf

An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.

Computational Cell Biology

Christopher P. Fall,Eric S. Marland,John M. Wagner,John J. Tyson
Computational Cell Biology Book PDF

Author : Christopher P. Fall,Eric S. Marland,John M. Wagner,John J. Tyson
Publisher : Springer Science & Business Media
Page : 484 pages
File Size : 50,6 Mb
Release : 2007-06-04
Category : Science
ISBN : 9780387224596

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Computational Cell Biology by Christopher P. Fall,Eric S. Marland,John M. Wagner,John J. Tyson Pdf

This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.

Biological and Biochemical Oscillators

Britton Chance,Amal K. Ghosh,E. Kendall Pye
Biological and Biochemical Oscillators Book PDF

Author : Britton Chance,Amal K. Ghosh,E. Kendall Pye
Publisher : Academic Press
Page : 552 pages
File Size : 51,5 Mb
Release : 2014-06-28
Category : Science
ISBN : 9781483271194

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Biological and Biochemical Oscillators by Britton Chance,Amal K. Ghosh,E. Kendall Pye Pdf

Biological and Biochemical Oscillators compiles papers on biochemical and biological oscillators from a theoretical and experimental standpoint. This book discusses the oscillatory behavior, excitability, and propagation phenomena on membranes and membrane-like interfaces; two-dimensional analysis of chemical oscillators; and chemiluminescence in oscillatory oxidation reactions catalyzed. The problems associated with the computer simulation of oscillating systems; mechanism of single-frequency glycolytic oscillations; excitation wave propagation during heart fibrillation; and biochemical cycle of excitation are also elaborated. This compilation likewise covers the physiological rhythms in Saccharomyces cerevisiae populations; integral and indissociable property of eukaryotic gene-action systems; and role of actidione in the temperature jump response of the circadian rhythm in Euglena gracilis. This publication is valuable to biochemists interested in biochemical and biological oscillations.

The Biological Clock

Frank A. Brown,J. Woodland Hastings,John D. Palmer
The Biological Clock Book PDF

Author : Frank A. Brown,J. Woodland Hastings,John D. Palmer
Publisher : Academic Press
Page : 103 pages
File Size : 53,8 Mb
Release : 2014-06-28
Category : Science
ISBN : 9781483282282

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The Biological Clock by Frank A. Brown,J. Woodland Hastings,John D. Palmer Pdf

The Biological Clock describes the rhythmic processes in a great variety of plants and animals. This book is an outgrowth of the 1969 James Arthur Lecture Series on "Time and its Mysteries" held at New York University. This three-chapter work begins with the basic principles of biological rhythms and clocks, along with various diagrams to illustrate some aspects of circadian rhythms in animals. The second chapter discusses the hypothesis of environmental timing of the clock. This chapter explores numerous research studies on phenomenon of biological rhythms, the nature of the rhythmic mechanism, and hormonal regulation. The third chapter examines the cellular-biochemical clock hypothesis and its contribution in the progress of understanding the complexity of biological rhythm. This book is intended primarily for biologists, behaviorists, and researchers.

Biological Rhythms and Medicine

A. Reinberg,M. H. Smolensky
Biological Rhythms and Medicine Book PDF

Author : A. Reinberg,M. H. Smolensky
Publisher : Springer Science & Business Media
Page : 313 pages
File Size : 55,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461394969

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Biological Rhythms and Medicine by A. Reinberg,M. H. Smolensky Pdf

During the past decade many review papers and books have been devoted to descriptions and analyses of biological rhythms (chronobiology) in plants and animals. These contributed greatly to demonstrating the impor tance of bioperiodicities in living beings in general. However, the practi cal aspects of chronobiology with regard to human health and improving the treatment of disease have not yet been a major focus of publication. One of our aims is to establish the relevance of biological rhythms to the practice of medicine. Another is to organize and convey in a simple fashion information pertinent to health- and life-science professionals so that students, researchers, and practitioners can achieve a clear and pre cise understanding of chronobiology. We have limited scientific jargon to unavoidable basic and well-defined terms and we have emphasized illus trative examples of facts and concepts rather than theories or hypotheti cal mechanisms. This volume is divided into seven chapters, each of which is compre hensive in its treatment and includes an extensive bibliography. The book is organized to serve as a textbook and/or reference handbook of modem applied chronobiology. Chapter 1 describes the historical development of chronobiology and reviews why, when, and how major concepts were introduced, accepted, and transformed.

An Introduction to Biological Rhythms

John Palmer
An Introduction to Biological Rhythms Book PDF

Author : John Palmer
Publisher : Elsevier
Page : 394 pages
File Size : 44,9 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323152426

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An Introduction to Biological Rhythms by John Palmer Pdf

An Introduction to Biological Rhythms provides an introduction to the subject of biological rhythms. The opening chapters present an overview of biological rhythms, their properties, and clock control, followed by a survey of rhythms in plants and animals. The subsequent chapters cover tidal rhythms and human rhythms; sun-compass, star-compass, and moon compass orientation of animals; the clock control of plant and animal photoperiodism; evidence for external timing of biological clocks; and models and mechanisms for endogenous timekeeping. The book also includes biographical sketches of Dr. Frank A. Brown, Jr., Morrison Professor of Biology at Northwestern University; and Dr. Leland N. Edmunds, Jr., Professor and Head of the Division of Biological Sciences at the Stony Brook campus of the State University of New York. This book is meant for the inquiring student seeking an introduction to the subject and for busy biologists in other fields who want to get a ""feel"" for the subject. It can also serve as a basic textbook for the existing biorhythms courses and act as a seed for the inauguration of new courses.

Cellular Rhythms and Networks

Qing Yan
Cellular Rhythms and Networks Book PDF

Author : Qing Yan
Publisher : Springer
Page : 87 pages
File Size : 53,6 Mb
Release : 2015-10-27
Category : Science
ISBN : 9783319228198

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Cellular Rhythms and Networks by Qing Yan Pdf

​This book provides an overview of circadian rhythms and cellular networks in their relation to biological systems and dynamical medicine. Six concise chapters explore circadian cell rhythms and biomarkers in inflammation, cardiovascular disease, cancer, depression, and more in causing and treating these ailments. The final chapter discusses optimization of drug delivery and individualized treatment systems using chronotherapy and chronobiology-based biomarkers as a general system of medicine. Succinct yet comprehensive, Cellular Rhythms and Networks, part of SpringerBriefs in Cell Biology presents a novel framework for clinical applications in personalized and systems medicine. It is invaluable reading for researchers and clinicians in cell biology, mood disorders, and systems medicine.

Biological Oscillators: Their Mathematical Analysis

Theodosios Pavlidis
Biological Oscillators Their Mathematical Analysis Book PDF

Author : Theodosios Pavlidis
Publisher : Elsevier
Page : 222 pages
File Size : 46,8 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323159821

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Biological Oscillators: Their Mathematical Analysis by Theodosios Pavlidis Pdf

Biological Oscillators: Their Mathematical Analysis introduces the main features of the dynamic properties of biological oscillators and the mathematical techniques necessary for their investigation. It is not a comprehensive description of all known biological oscillators, since this would require a much bigger volume as well as a different type of expertise. Instead certain classes of biological oscillators are described, and then only in as much detail as required for the study of their dynamics. The opening chapter reviews fundamental mathematical concepts and techniques which will be used in the remainder of the book. These include phase plane techniques; asymptotic techniques of Krylov, Bogoliubov, and Mitopolski; and the describing function. Subsequent chapters discuss examples of biological oscillators; phase shifts and phase response curves; the entrainment of oscillators by external inputs; the dynamics of circadian oscillators; effects of changing environment on the dynamics of biological oscillators; the features peculiar to populations of interacting oscillators; and biological phenomena attributable to populations of oscillators.

Chronobioengineering

Donald McEachron
Chronobioengineering Book PDF

Author : Donald McEachron
Publisher : Morgan & Claypool Publishers
Page : 288 pages
File Size : 48,6 Mb
Release : 2012-10-01
Category : Technology & Engineering
ISBN : 9781598296365

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Chronobioengineering by Donald McEachron Pdf

This book represents the first in a two-volume set on biological rhythms. This volume focuses on supporting the claim that biological rhythms are universal and essential characteristics of living organisms, critical for proper functioning of any living system. The author begins by examining the potential reasons for the evolution of biological rhythms: (1) the need for complex, goal-oriented devices to control the timing of their activities; (2) the inherent tendency of feedback control systems to oscillate; and (3) the existence of stable and powerful geophysical cycles to which all organisms must adapt. To investigate the second reason, the author enlists the help of biomedical engineering students to develop mathematical models of various biological systems. One such model involves a typical endocrine feedback system. By adjusting various model parameters, it was found that creating a oscillation in any component of the model generated a rhythmic cascade that made the entire system oscillate. This same approach was used to show how daily light/dark cycles could cascade rhythmic patterns throughout ecosystems and within organisms. Following up on these results, the author discusses how the twin requirements of internal synchronization (precise temporal order necessary for the proper functioning of organisms as complex, goal-oriented devices) and external synchronization (aligning organisms' behavior and physiology with geophysical cycles) supported the evolution of biological clocks. The author then investigates the clock systems that evolved using both conceptual and mathematical models, with the assistance of Dr. Bahrad Sokhansanj, who contributes a chapter on mathematical formulations and models of rhythmic phenomena. With the ubiquity of biological rhythms established, the author suggests a new classification system: the F4LM approach (Function; Frequency; waveForm; Flexibility; Level of biological system expressing rhythms; and Mode of rhythm generation) to investigate biological rhythms. This approach is first used on the more familiar cardiac cycle and then on neural rhythms as exemplified and measured by the electroencephalogram. During the process of investigating neural cycles, the author finds yet another reason for the evolution of biological rhythms: physical constraints, such as those imposed upon long distance neural signaling. In addition, a common theme emerges of a select number of autorhythmic biological oscillators imposing coherent rhythmicity on a larger network or system. During the course of the volume, the author uses a variety of observations, models, experimental results, and arguments to support the original claim of the importance and universality of biological rhythms. In Volume 2, the author will move from the establishment of the critical nature of biological rhythms to how these phenomena may be used to improve human health, well-being, and productivity. In a sense, Volume 1 focuses on the chronobio aspect of chronobioengineering while Volume 2 investigates methods of translating this knowledge into applications, the engineering aspect of chronobioengineering.

A Time for Metabolism and Hormones

Paolo Sassone-Corsi,Yves Christen
A Time for Metabolism and Hormones Book PDF

Author : Paolo Sassone-Corsi,Yves Christen
Publisher : Springer
Page : 132 pages
File Size : 49,9 Mb
Release : 2016-04-04
Category : Medical
ISBN : 9783319270692

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A Time for Metabolism and Hormones by Paolo Sassone-Corsi,Yves Christen Pdf

Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Circadian Medicine

Christopher S. Colwell
Circadian Medicine Book PDF

Author : Christopher S. Colwell
Publisher : John Wiley & Sons
Page : 405 pages
File Size : 48,8 Mb
Release : 2015-07-07
Category : Medical
ISBN : 9781118467787

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Circadian Medicine by Christopher S. Colwell Pdf

Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.

The Circadian Clock

Urs Albrecht
The Circadian Clock Book PDF

Author : Urs Albrecht
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 48,5 Mb
Release : 2010-01-23
Category : Science
ISBN : 9781441912626

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The Circadian Clock by Urs Albrecht Pdf

With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.

Aging and Biological Rhythms

H. V. Samis
Aging and Biological Rhythms Book PDF

Author : H. V. Samis
Publisher : Springer Science & Business Media
Page : 345 pages
File Size : 42,6 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781475744606

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Aging and Biological Rhythms by H. V. Samis Pdf

Aging is one of the most serious and costly health problems in the Western world. A disproportionate amount of the available health care capability is devoted to the health care of the aged and the cost of this care is soaring. Viewed in wide perspective, aging presents two problems for the researcher's consideration. First is that of providing the most efficacious therapeutic regi mens and the best possible care for those already in their latter years. The second is to determine the cause or causes for senes cence and all its attendant problems in order to decrease the im pact of senescence on general health and well being. This volume is aimed at examining possible relationships be tween biological time structure and aging and ways by which these interrelationships might be examined in terms of both the causes of senescence and the management of health problems of the elderly. The purpose of the volume is to stir the interests of chronobiolo gists in gerontology and those of gerontologists and geriatricians in chronobiology.