Biochemistry And Disease

Author : Eric Newsholme,Anthony Leech
Publisher : John Wiley & Sons
Page : 564 pages
File Size : 45,6 Mb
Release : 2011-09-09
Category : Science
ISBN : 9781119965244

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Functional Biochemistry in Health and Disease by Eric Newsholme,Anthony Leech Pdf

Functional Biochemistry in Health and Disease provides a clear and straightforward account of the biochemistry that is necessary to understand the physiological functions of tissues or organs essential to the life of human beings. Focusing on the dynamic aspects of biochemistry and its application to the basic functions of the body, the book bridges the gap between biochemistry and medical practice. Carefully structured within five sections, each biochemical, physiological or medical subject that is covered in the book is presented in one complete chapter. Consequently, each subject can be read and studied in isolation although cross-sectional links between the subjects are included where necessary. Background material, both biochemical and medical, that is necessary for an understanding of the subject, is included at the start of each chapter and clear, relevant diagrams enhance students' understanding. * Focuses on medically relevant aspects of biochemistry written from a physiological rather than a chemical perspective. * Clear presentation that minimises the use of jargon. * Each chapter contains boxes on related topics, relevant diagrams and a brief glossary. * Coverage includes athletic performance, apoptosis and the immune system. * Key historical developments are included to show how modern biochemistry has evolved. By linking biochemistry, medical education and clinical practice this book will prove invaluable to students in medical and health sciences, biomedical science and human biology taking an introductory biochemistry course. In addition it will appeal to biochemistry and biology students interested in clinical applications of biochemistry.

Author : Robert M. Cohn,Karl S. Roth
Publisher : Lippincott Williams & Wilkins
Page : 614 pages
File Size : 52,5 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015037827964

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Biochemistry and Disease by Robert M. Cohn,Karl S. Roth Pdf

A text for first year medical students and for nursing and physical assistant students seeking to understand the applicability of the basic sciences to the practice of medicine. It provides a foundation for clinical approaches by emphasizing pathobiochemistry. Coverage found in introductory biochemi.

Author : Edward C.C. Wong,Dennis J. Dietzen,Michael J. Bennett,Shannon Haymond
Publisher : Academic Press
Page : 1172 pages
File Size : 47,7 Mb
Release : 2021-05-13
Category : Science
ISBN : 9780128179635

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Biochemical and Molecular Basis of Pediatric Disease by Edward C.C. Wong,Dennis J. Dietzen,Michael J. Bennett,Shannon Haymond Pdf

Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases. Provides a fully-updated resource with more color illustrations Focuses on the biochemical and molecular basis of disease as well as the analytical techniques Defines important differences in the pathophysiology of diseases, comparing childhood with adult

Author : Miriam D. Rosenthal,Robert H. Glew
Publisher : John Wiley & Sons
Page : 455 pages
File Size : 41,9 Mb
Release : 2011-09-20
Category : Science
ISBN : 9781118210291

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Medical Biochemistry by Miriam D. Rosenthal,Robert H. Glew Pdf

Metabolism includes various pathways of chemical reactions; understanding these pathways leads to an improved knowledge of the causes, preventions, and cures for human diseases. Medical Biochemistry: Human Metabolism in Health and Disease provides a concise yet thorough explanation of human metabolism and its role in health and diseases. Focusing on the physiological context of human metabolism without extensive consideration of the mechanistic principles of underlying enzymology, the books serves as both a primary text and resource for students and professional in medical, dental, and allied health programs.

Author : George Feuer,F. A. de LA Iglesia
Publisher : CRC Press
Page : 248 pages
File Size : 53,5 Mb
Release : 1985-05
Category : Science
ISBN : UOM:49015000413972

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MOLECULAR BIOCHEMISTRY OF HUMAN DISEASES by George Feuer,F. A. de LA Iglesia Pdf

Author : J. J. Kaneko,C. E. Cornelius
Publisher : Academic Press
Page : 456 pages
File Size : 41,9 Mb
Release : 2014-05-10
Category : Technology & Engineering
ISBN : 9781483274171

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Clinical Biochemistry of Domestic Animals by J. J. Kaneko,C. E. Cornelius Pdf

Clinical Biochemistry of Domestic Animals, Second Edition, Volume I, is a major revision of the first edition prompted by the marked expansion of knowledge in the clinical biochemistry of animals. In keeping with this expansion of knowledge, this edition is comprised of two volumes. Chapters on the pancreas, thyroid, and pituitary-adrenal systems have been separated and entirely rewritten. Completely new chapters on muscle metabolism, iron metabolism, blood clotting, and gastrointestinal function have been added. All the chapters of the first edition have been revised with pertinent new information, and many have been completely rewritten. This volume contains 10 chapters and opens with a discussion of carbohydrate metabolism and associated disorders. Separate chapters follow on lipid metabolism, plasma proteins, and porphyrins. Subsequent chapters deal with liver, pancreatic, and thyroid functions; the role of the pituitary and adrenal glands in health and disease; the function of calcium, inorganic phosphorus, and magnesium metabolism in health and disease; and iron metabolism.

Author : Toshitaka Oohashi,Hirokazu Tsukahara,Francesco Ramirez,Chad L. Barber,Fumio Otsuka
Publisher : Springer
Page : 349 pages
File Size : 50,8 Mb
Release : 2019-03-13
Category : Medical
ISBN : 9789811329777

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Human Pathobiochemistry by Toshitaka Oohashi,Hirokazu Tsukahara,Francesco Ramirez,Chad L. Barber,Fumio Otsuka Pdf

This textbook uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 29 clinical cases have been carefully selected to cover key scientific concepts and some common, and other not so common, diseases. While the principal focus is on topics relating to metabolic disease, further subjects such as connective tissue disorders, neurological disorders, auto-inflammatory disorders, infective diseases, and cancer are also addressed. Each chapter provides a specific patient report that includes the natural history, pertinent clinical laboratory data, physical findings, subsequent diagnosis, and therapy. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. Graphical diagrams are provided in each chapter for ease of comprehension.

Author : Eric D. Wills
Publisher : Butterworth-Heinemann
Page : 654 pages
File Size : 51,6 Mb
Release : 2014-04-24
Category : Science
ISBN : 9781483193496

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Biochemical Basis of Medicine by Eric D. Wills Pdf

Biochemical Basis of Medicine discusses academic biochemistry and the applications of biochemistry in medicine. This book deals with the biochemistry of the subcellular organelles, the biochemistry of the body , and of the specialized metabolism occurring in many body tissues. This text also discusses the various applications of biochemistry as regards environmental hazards, as well as in the diagnosis of illnesses and their treatment. This text explains the structure of the mammalian cell, the cell's metabolism, the nutritional requirements of the whole body, and the body's metabolism. This book explains the specialized metabolisms involved in tissues such as those occurring in blood clotting, in the liver during carbohydrate metabolism, or in the kidneys during water absorption. The text explains toxicology or biochemical damage caused by excess presence of copper, mercury, or lead in the body. Chelation therapy can remove these toxic metals. This book describes the effects of alcohol on plasma liquids, the multistage concept of carcinogenesis, and the biochemical basis of diagnosis. Diagnosis and treatment include the determination of typical enzymes found in the plasma, tests for genetic defects in blood proteins, and the use of chemotherapeutic drugs. This book is suitable for chemists, students and professors in organic chemistry, and laboratory technicians whose work is related to pharmacology.

Author : William J. Marshall,S. K. Bangert
Publisher : Elsevier Health Sciences
Page : 997 pages
File Size : 44,6 Mb
Release : 2008-01-01
Category : Medical
ISBN : 9780443101861

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Clinical Biochemistry by William J. Marshall,S. K. Bangert Pdf

Now fully revised and updated, Clinical Biochemistry, third edition is essential reading for specialty trainees, particularly those preparing for postgraduate examinations. It is also an invaluable current reference for all established practitioners, including both medical and scientist clinical biochemists. Building on the success of previous editions, this leading textbook primarily focuses on clinical aspects of the subject, giving detailed coverage of all conditions where clinical biochemistry is used in diagnosis and management - including nutritional disorders, diabetes, inherited metabolic disease, metabolic bone disease, renal calculi and dyslipidaemias. The acquisition and interpretation of clinical biochemical data are also discussed in detail. Expanded sections on haematology and immunology for clinical biochemists provide a thorough understanding of both laboratory and clinical aspects New chapters are included on important evolving areas such as the metabolic response to stress, forensic aspects of clinical biochemistry and data quality management An extended editorial team - including three expert new additions - ensures accuracy of information and relevance to current curricula and clinical practice A superb new accompanying electronic version provides an enhanced learning experience and rapid reference anytime, anywhere! Elsevier ExpertConsult.com Enhanced eBooks for medical professionals Compatible with PC, Mac®, most mobile devices and eReaders, browse, search, and interact with this title - online and offline. Redeem your PIN at expertconsult.com today! Straightforward navigation and search across all Elsevier titles Seamless, real-time integration between devices Adjustable text size and brightness Notes and highlights sharing with other users through social media Interactive content

Author : Gerald Litwack
Publisher : Academic Press
Page : 1272 pages
File Size : 51,7 Mb
Release : 2008-01-08
Category : Science
ISBN : 0080924352

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Human Biochemistry and Disease by Gerald Litwack Pdf

This textbook is specifically designed for upper-division undergraduate or graduate students in life science or pre-medical majors including dentistry or pharmacology, who are required to take a biochemistry or medical biochemistry course, but who are not necessarily biochemistry majors. The book adopts a unique approach to the topic compared with other biochemistry textbooks currently available, in that each biochemical subject is introduced by a human disease relating the biochemical principles to be developed in that chapter. The goal is to make biochemistry more meaningful to the student who is not normally shown the connection between biochemistry and medicine. * Includes an abundance of figures * Emphasizes human biochemistry * Introduces each chapter with a relevant disease or clinical relationship

Author : E. A. Newsholme
Publisher : Unknown
Page : 543 pages
File Size : 41,9 Mb
Release : 2010
Category : Biochemistry
ISBN : OCLC:647899180

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Functional Biochemistry in Health and Disease by E. A. Newsholme Pdf

Author : Robert H. Glew,Miriam D. Rosenthal
Publisher : Oxford University Press
Page : 388 pages
File Size : 44,6 Mb
Release : 2006-08-24
Category : Medical
ISBN : 9780195176872

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Clinical Studies in Medical Biochemistry by Robert H. Glew,Miriam D. Rosenthal Pdf

This edition uses actual clinical cases to illustrate important principles of biochemistry and molecular biology in the context of human disease. The format of each chapter remains the same - case presentation, diagnosis, therapy and references.

Author : J. Robin Harris,Viktor I. Korolchuk
Publisher : Springer
Page : 499 pages
File Size : 41,8 Mb
Release : 2019-03-19
Category : Medical
ISBN : 9789811336812

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Biochemistry and Cell Biology of Ageing: Part II Clinical Science by J. Robin Harris,Viktor I. Korolchuk Pdf

This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.

Author : Lorrie A. Kirshenbaum
Publisher : Springer Nature
Page : 293 pages
File Size : 42,5 Mb
Release : 2021-11-29
Category : Science
ISBN : 9783030787998

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Biochemistry of Apoptosis and Autophagy by Lorrie A. Kirshenbaum Pdf

One of the most intriguing and compelling issues to impact contemporary biology to date is the concept that cell death is genetically regulated. Observations by Kerr and Wyllie, made more than 30 years ago on the basis of distinct morphological criteria, markedly distinguished apoptosis from classical cell death by necrosis. Apoptosis is a highly regulated, evolutionary conserved, genetic program of cell death essential for normal development and tissue homeostasis. The discovery of apoptosis as a regulated event and potentially amenable to therapeutic interventions has generated considerable excitement because it meant that disease entities resulting from either too much, or too little, apoptosis could be potentially cured with new therapies that target apoptosis. While there is little doubt that necrosis induced by massive cellular trauma is likely an unregulated event, several lines of investigation have challenged the dogma that necrotic cell death is merely unregulated. Emerging data has shifted the paradigm in our thinking about necrosis as a regulated event. Autophagy is another cellular process that has received considerable attention over the past two decades and its remarkable involvement in the processes of cell survival, death and tumorigenesis. Macro autophagy is a catabolic process that involves the selective and targeted removal of oxidized proteins, macromolecular structures and organelles through an elaborate cellular process involving a lysosome mediated pathway. Other forms of autophagy involving adapter proteins, commonly referred to as chaperone mediated autophagy, involves the selective removal of cellular cargo by the ubiquitin-proteasome pathway. The book will serve as a reference guide for basic and clinical scientists who are interested in understanding how these critical cellular processes impact the pathogenesis of human disease.

Author : Antonio Blanco,Gustavo Blanco
Publisher : Academic Press
Page : 910 pages
File Size : 45,7 Mb
Release : 2022-03-23
Category : Science
ISBN : 9780323916004

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Medical Biochemistry by Antonio Blanco,Gustavo Blanco Pdf

This second edition of Medical Biochemistry is supported by more than 45 years of teaching experience, providing coverage of basic biochemical topics, including the structural, physical, and chemical properties of water, carbohydrates, lipids, proteins, and nucleic acids. In addition, the general aspects of thermodynamics, enzymes, bioenergetics, and metabolism are presented in straightforward and easy-to-comprehend language. This book ties these concepts into more complex aspects of biochemistry using a systems approach, dedicating chapters to the integral study of biological phenomena, including cell membrane structure and function, gene expression and regulation, protein synthesis and post-translational modifications, metabolism in specific organs and tissues, autophagy, cell receptors, signal transduction pathways, biochemical bases of endocrinology, immunity, vitamins and minerals, and hemostasis. The field of biochemistry is continuing to grow at a fast pace. This edition has been revised and expanded with all-new sections on the cell plasma membrane, the human microbiome, autophagy, noncoding, small and long RNAs, epigenetics, genetic diseases, virology and vaccines, cell signaling, and different modes of programmed cell death. The book has also been updated with full-color figures, new tables, chapter summaries, and further medical examples to improve learning and better illustrate the concepts described and their clinical significance. Integrates basic biochemistry principles with molecular biology and molecular physiology Illustrates basic biochemical concepts through medical and physiological examples Utilizes a systems approach to understanding biological phenomena Fully updated for recent studies and expanded to include clinically relevant examples and succinct chapter summaries