Bioconjugation

Author : Greg T. Hermanson
Publisher : Academic Press
Page : 1233 pages
File Size : 55,7 Mb
Release : 2010-07-26
Category : Science
ISBN : 9780080568720

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Bioconjugate Techniques by Greg T. Hermanson Pdf

Bioconjugate Techniques, 2nd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or cross linking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates More than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates Includes entirely new chapters on the latest areas in the field of bioconjugation as follows: Microparticles and nanoparticlesSilane coupling agentsDendrimers and dendronsChemoselective ligationQuantum dotsLanthanide chelatesCyanine dyesDiscrete PEG compoundsBuckyballs,fullerenes, and carbon nanotubesMass tags and isotope tagsBioconjugation in the study of protein interactions

Author : Christof M. Niemeyer
Publisher : Springer Science & Business Media
Page : 329 pages
File Size : 41,8 Mb
Release : 2008-02-04
Category : Science
ISBN : 9781592598137

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Bioconjugation Protocols by Christof M. Niemeyer Pdf

There are a number of outstanding volumes that provide a comprehensive overview of bioconjugation techniques. However, many of the conventional approaches to the synthesis of chemically modified protein conjugates lack efficient means to control the stoichiometry of conjugation, as well as the s- cific site of attachment of the conjugated moiety. Moreover, the recent dev- opments in microarray technologies as well as in nanobiotechnology—a novel field of research rapidly evolving at the crossroads of physics, chemistry, b- technology, and materials science—call for a summary of modern bioconjugation strategies to overcome the limitations of the classical approaches. Bioconjugation Protocols: Methods and Strategies is intended to provide an update of many of the classic techniques and also to introduce and summarize newer approaches that go beyond the pure biomedical applications of bioconjugation. The purpose of Bioconjugation Protocols: Methods and Str- egies is therefore to provide instruction and inspiration for all those scientists confronting the challenges of semisynthesizing functional biomolecular reagents for a wide variety of applications ranging from novel biomedical diagnostics, to therapeutics, to biomaterials. Part I contains seven protocols for the preparation of protein conjugates.

Author : Ravin Narain
Publisher : John Wiley & Sons
Page : 934 pages
File Size : 54,9 Mb
Release : 2013-12-02
Category : Science
ISBN : 9781118776377

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Chemistry of Bioconjugates by Ravin Narain Pdf

Explores bioconjugate properties and applications of polymers, dendrimers, lipids, nanoparticles, and nanotubes Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine. With its emphasis on synthesis, properties and applications, this book enables readers to understand the connection between chemistry and the biological application of bioconjugated materials. Its detailed descriptions of methods make it possible for researchers to fabricate and take full advantage of bioconjugates for a broad range of applications. Moreover, the book sets the foundation for the development of new applications, including assays, imaging, biosensors, drug delivery, and diagnostics. Chemistry of Bioconjugates features contributions from an international team of leading experts and pioneers in the field. These contributions reflect the authors’ firsthand laboratory experience as well as a thorough review of the current literature. The book’s six sections examine: General methods of bioconjugation Polymer bioconjugates Organic nanoparticle-based bioconjugates Inorganic nanomaterial bioconjugates, including metals and metal oxides Cell-based, hydrogel/microgel, and glyco-bioconjugates Characterization, physico-(bio)chemical properties, and applications of bioconjugates This comprehensive exploration of bioconjugates includes discussions of polymers, dendrimers, lipids, nanoparticles, and nanotubes. References at the end of each chapter serve as a gateway to the most important original research findings and reviews in the field. By drawing together and analyzing all the latest chemical methods and research findings on the physico-chemical and biochemical properties of bioconjugates, Chemistry of Bioconjugates sheds new light on the significance and potential of bioconjugation. The book is recommended for organic and polymer chemists, biochemists, biomaterial scientists, carbohydrate chemists, biophysicists, bioengineers, and drug and gene delivery scientists.

Author : Annette Barchanski
Publisher : Springer
Page : 310 pages
File Size : 45,6 Mb
Release : 2016-05-27
Category : Science
ISBN : 9783658135157

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Laser-Generated Functional Nanoparticle Bioconjugates by Annette Barchanski Pdf

Annette Barchanski deals with the question how to design nanoparticles for biomedical research. She considers properties such as size, charge, biocompatibility, and functionalization of nanoparticles from a biologist’s point of view in order to achieve specific cellular responses. The author discusses the structure-function relationship of nanoparticle conjugates derived from a laser-based fabrication method. Both the limits and perspectives of tunable conjugate functions are presented, providing a general outline for researchers to configure functionalized nanoparticles with a specifically optimized design for biomedical requests, e.g. in biomedical engineering regenerative science and reproductive biology.

Author : Sandeep Kumar Verma,Ashok Kumar Das
Publisher : Elsevier
Page : 260 pages
File Size : 44,5 Mb
Release : 2023-06-07
Category : Science
ISBN : 9780443132001

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Bioconjugated Materials Part 1 by Sandeep Kumar Verma,Ashok Kumar Das Pdf

Bioconjugated Materials Part 1, Volume 102 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on bioconjugated materials. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Comprehensive Analytical Chemistry series Updated release includes the latest information on Airborne Conjugated Materials

Author : Anonim
Publisher : Elsevier
Page : 334 pages
File Size : 44,8 Mb
Release : 2023-11-03
Category : Science
ISBN : 9780443221996

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Bioconjugated Materials Part 2 - Applications in Drug delivery, Vaccine formulations and Important conjugates for cancer therapy by Anonim Pdf

Bioconjugated Materials Part 2, Volume 103 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on bioconjugated materials. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Comprehensive Analytical Chemistry series Updated release includes the latest information on Isotope Dilution

Author : Jeet Kalia
Publisher : Unknown
Page : 244 pages
File Size : 55,6 Mb
Release : 2008
Category : Electronic
ISBN : WISC:89100587013

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Bioconjugation by Jeet Kalia Pdf

Author : Mohammed Aslam,Alastair Dent
Publisher : Stockton Press
Page : 854 pages
File Size : 41,8 Mb
Release : 1998
Category : Medical
ISBN : UVA:X004276134

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Bioconjugation by Mohammed Aslam,Alastair Dent Pdf

Written by two leading experts in the field, Bioconjugation offers invaluable guidance for the design of protein conjugates of all types, covering the coupling of proteins to organic molecules, nucleic acids and solid phases as well as other proteins. Its comprehensive coverage saves time by bringing together information previously available only form a wide variety of sources. An essential reference for college and university libraries supporting research in biochemistry, immunology and medicine.

Author : Mariette M. Pereira,Sara M.A. Pinto,Lucas D. Dias
Publisher : CRC Press
Page : 158 pages
File Size : 43,6 Mb
Release : 2024-06-26
Category : Science
ISBN : 9781040038864

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Synthesis of Pyrrol-based Bioconjugates by Mariette M. Pereira,Sara M.A. Pinto,Lucas D. Dias Pdf

In recent years, the use of bioconjugation as strategy for development of more specific and directed drugs has been widely researched. Tetrapyrrolic macrocycles are one of the most common families of organic compounds applied in medicinal chemistry, specifically for diagnosis and therapy. For optimization of their efficiency as therapeutic molecules, it is relevant to promote their linking to biomolecules capable of targeting altered cells. This work brings a new dimension to the literature by combining structural modification of biomolecules and polymers with pyrrole-based compounds. It will be of great interest to academicians, industrialists, and undergraduate and graduate students of chemistry, biosciences, and pharmacy since, as apart from the theoretical aspects, it discusses experimental components. Features: Discusses methods for protein modification. Useful for academicians, industrialists and undergraduate and graduated students of chemistry, biosciences, and pharmacy. Explains the synthesis of pyrrole-based molecules.

Author : W. Russ Algar,Philip Dawson,Igor L. Medintz
Publisher : John Wiley & Sons
Page : 766 pages
File Size : 50,5 Mb
Release : 2017-06-19
Category : Technology & Engineering
ISBN : 9783527334360

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Chemoselective and Bioorthogonal Ligation Reactions by W. Russ Algar,Philip Dawson,Igor L. Medintz Pdf

This timely, one-stop reference is the first on an emerging and interdisciplinary topic. Covering both established and recently developed ligation chemistries, the book is divided into two didactic parts: a section that focuses on the details of bioorthogonal and chemoselective ligation reactions at the level of fundamental organic chemistry, and a section that focuses on applications, particularly in the areas of chemical biology, biomaterials, and bioanalysis, highlighting the capabilities and benefits of the ligation reactions. With chapters authored by outstanding scientists who range from trailblazers in the field to young and emerging leaders, this book on a highly interdisciplinary topic will be of great interest for biochemists, biologists, materials scientists, pharmaceutical chemists, organic chemists, and many others.

Author : Sabu Thomas
Publisher : Springer Nature
Page : 483 pages
File Size : 45,9 Mb
Release : 2024-06-28
Category : Electronic
ISBN : 9783031547799

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Quantum Dots Based Nanocomposites by Sabu Thomas Pdf

Author : Trung Nguyẽ̂n
Publisher : Unknown
Page : 248 pages
File Size : 48,8 Mb
Release : 2006
Category : Electronic
ISBN : UCAL:C3507472

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New Chromophores and Chromatography Methods for Protein Bioconjugation Reactions by Trung Nguyẽ̂n Pdf

Author : Mohammed Aslam,Alastair Dent
Publisher : Unknown
Page : 856 pages
File Size : 47,5 Mb
Release : 1998
Category : Biochemistry
ISBN : PSU:000056868074

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Bioconjugation by Mohammed Aslam,Alastair Dent Pdf

Recent years have seen an enormous increase in the use of protein reagents in the biological and medical sciences. Enzyme conjugates and immobilised proteins are fundamental to many diagnostic applications, and existing therapeutic advances are being made using a range of approaches based on antibody conjugates. Protein conjugation techniques are central to the development of these reagents.

Author : Thomas John Wydrzynski,Warwick Hillier
Publisher : Royal Society of Chemistry
Page : 577 pages
File Size : 44,7 Mb
Release : 2012
Category : Science
ISBN : 9781849730341

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Molecular Solar Fuels by Thomas John Wydrzynski,Warwick Hillier Pdf

Written by experts, this book presents the latest knowledge and chemical prospects in developing hydrogen as a solar fuel.

Author : Bruno Sarmento,Jose Das Neves
Publisher : William Andrew
Page : 778 pages
File Size : 52,8 Mb
Release : 2018-03-01
Category : Science
ISBN : 9780323508797

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Biomedical Applications of Functionalized Nanomaterials by Bruno Sarmento,Jose Das Neves Pdf

Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation presents a concise overview of the most promising nanomaterials functionalized with ligands for biomedical applications. The first section focuses on current strategies for identifying biological targets and screening of ligand to optimize anchoring to nanomaterials, providing the foundation for the remaining parts. Section Two covers specific applications of functionalized nanomaterials in therapy and diagnostics, highlighting current practice and addressing major challenges, in particular, case studies of successfully developed and marketed functionalized nanomaterials. The final section focuses on regulatory issues and clinical translation, providing a legal framework for their use in biomedicine. This book is an important reference source for worldwide drug and medical devices policymakers, biomaterials scientists and regulatory bodies. Provides an overview of the methodologies for biological target identification and ligand screening Includes case studies showing the development of functionalized nanomaterials and their biomedical applications Highlights the importance of functionalized nanomaterials for drug delivery, diagnostics and regenerative medicine applications