Bioengineering And Biotechnology Approaches In Cardiovascular Regenerative Medicine Volume Ii

Author : Jianyi Zhang,Zhen Ma,Vahid Serpooshan,Yuji Nakada,Keiichi Fukuda
Publisher : Frontiers Media SA
Page : 234 pages
File Size : 41,8 Mb
Release : 2024-02-26
Category : Technology & Engineering
ISBN : 9782832545263

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Bioengineering and Biotechnology Approaches in Cardiovascular Regenerative Medicine, Volume II by Jianyi Zhang,Zhen Ma,Vahid Serpooshan,Yuji Nakada,Keiichi Fukuda Pdf

This Research Topic is Volume II of a series. The previous volume, which has attracted over 40,000 views can be found here: Bioengineering and Biotechnology Approaches in Cardiovascular Regenerative MedicineCardiovascular diseases continue to be the leading cause of death while available clinical interventions have limited contributions to heart repair and regeneration. Cardiovascular regenerative medicine, characterized by a unique integration of biology, physical sciences, and bioengineering principles, has emerged as one of the most promising fields of translational research to regenerate the adult human heart.

Author : Jianyi Zhang,Vahid Serpooshan,James J. H. Chong,Philippe Menasché
Publisher : Frontiers Media SA
Page : 190 pages
File Size : 49,8 Mb
Release : 2021-10-04
Category : Science
ISBN : 9782889714629

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Bioengineering and Biotechnology Approaches in Cardiovascular Sciences by Jianyi Zhang,Vahid Serpooshan,James J. H. Chong,Philippe Menasché Pdf

Author : Jianyi Zhang,Vahid Serpooshan
Publisher : Springer Nature
Page : 407 pages
File Size : 51,6 Mb
Release : 2022-02-05
Category : Technology & Engineering
ISBN : 9783030861407

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Advanced Technologies in Cardiovascular Bioengineering by Jianyi Zhang,Vahid Serpooshan Pdf

This book presents a systematic overview of the technologies currently being explored and utilized in the fields of cardiovascular tissue engineering and regenerative medicine. Considering the unprecedented rapid progress occurring on multiple technological fronts in cardiac tissue engineering, this important new volume fills a need for an up-to-date, comprehensive text on emerging advanced biological and engineering tools. The book is an important resource for anyone looking to understand the emerging topics that have the potential to substantially influence the future of the field. Coverage includes iPS stem cell technologies, nanotechnologies and nanomedicine, advanced biomanufacturing, 3D culture systems, 3D organoid systems, genetic approaches to cardiovascular tissue engineering, and organ on a chip. This book will be a valuable guide for research scientists, students, and clinical researchers in the fields of cardiovascular biology, medicine, and bioengineering, as well as industry-based practitioners working in biomaterial science, nanomaterials and technology, and rapid prototyping and biomanufacturing (3D bioprinting).

Author : Vahid Serpooshan,Sean M. Wu
Publisher : Springer
Page : 233 pages
File Size : 45,5 Mb
Release : 2019-06-29
Category : Medical
ISBN : 9783030200473

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Cardiovascular Regenerative Medicine by Vahid Serpooshan,Sean M. Wu Pdf

This book is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of cardiovascular disease. It provides a much-needed review of the rapid development and evolution of bio-fabrication techniques to engineer cardiovascular tissues as well as their use in clinical settings. The book incorporates recent advances in the biology, biomaterial design, and manufacturing of bioengineered cardiovascular tissue with their clinical applications to bridge the basic sciences to current and future cardiovascular treatment. The book begins with an examination of state-of-the-art cellular, biomaterial, and macromolecular technologies for the repair and regeneration of diseased heart tissue. It discusses advances in nanotechnology and bioengineering of cardiac microtissues using acoustic assembly. Subsequent chapters explore the clinical applications and translational potential of current technologies such as cardiac patch-based treatments, cell-based regenerative therapies, and injectable hydrogels. The book examines how these methodologies are used to treat a variety of cardiovascular diseases including myocardial infarction, congenital heart disease, and ischemic heart injuries. Finally, the volume concludes with a summary of the most prominent challenges and perspectives on the field of cardiovascular tissue engineering and clinical cardiovascular regenerative medicine. Cardiovascular Regenerative Medicine is an essential resource for physicians, residents, fellows, and medical students in cardiology and cardiovascular regeneration as well as clinical and basic researchers in bioengineering, nanomaterial and technology, and cardiovascular biology.

Author : Tiago G. Fernandes,Maria Margarida Diogo,Joaquim M. S. Cabral
Publisher : Academic Press
Page : 284 pages
File Size : 41,9 Mb
Release : 2019-11-14
Category : Science
ISBN : 9780128166703

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Engineering Strategies for Regenerative Medicine by Tiago G. Fernandes,Maria Margarida Diogo,Joaquim M. S. Cabral Pdf

Engineering Strategies for Regenerative Medicine considers how engineering strategies can be applied to accelerate advances in regenerative medicine. The book provides relevant and up-to-date content on key topics, including the interdisciplinary integration of different aspects of stem cell biology and technology, diverse technologies, and their applications. By providing massive amounts of data on each individual, recent scientific advances are rapidly accelerating medicine. Cellular, molecular and genetic parameters from biological samples combined with clinical information can now provide valuable data to scientists, clinicians and ultimately patients, leading to the development of precision medicine. Equally noteworthy are the contributions of stem cell biology, bioengineering and tissue engineering that unravel the mechanisms of disease, regeneration and development. Considers how engineering strategies can accelerate novel advances in regenerative medicine Takes an interdisciplinary approach, integrating different aspects of research, technology and application Provides up-to-date coverage on this rapidly developing area of medicine Presents insights from an experienced and cross-disciplinary group of researchers and practitioners with close links to industry

Author : Ira S. Cohen,Glenn R. Gaudette
Publisher : Springer Science & Business Media
Page : 555 pages
File Size : 44,8 Mb
Release : 2011-03-23
Category : Science
ISBN : 9781617790218

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Regenerating the Heart by Ira S. Cohen,Glenn R. Gaudette Pdf

Medical research made huge strides in treating heart disease in the 20th century, from drug-eluding stents to automatic internal defibrillators. Public awareness of the dangers of heart disease has never been more pervasive. Now, though, ten years into a new millennium, scientists are gearing up for the next great challenges in tackling this pervasive condition. Cell therapy is going to be a key weapon in the fight against heart disease. It has the potential to address many cardiovascular conditions. From heart failure to atrioventricular nodal dysfunction, the young but promising field of cell therapy is set to play a significant role in developing the cures that the upcoming decades of hard work will yield. Regenerating the Heart: Stem Cells and the Cardiovascular System organizes the field into a digestible body of knowledge. Its four sections cover mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies. An array of talented researchers share the fruits of their labors, with chapters covering such crucial issues as the cardiogenic potential of varying stem cell types, the ways in which they might be used to tackle arrhythmias, their possible application to biological replacements for cardiac tissues such as valves, and the varying approaches used in the in vivo evaluation of stem cell therapies, including methods of delivering stem cells to the myocardium. This comprehensive survey of an area of research with such exciting potential is an invaluable resource both for veteran stem cell researchers who need to monitor fresh developments, and for newly minted investigators seeking inspirational examples.

Author : Kenneth D. Poss,Bernhard Kühn
Publisher : Humana
Page : 346 pages
File Size : 54,7 Mb
Release : 2021-09-12
Category : Science
ISBN : 1071606700

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Cardiac Regeneration by Kenneth D. Poss,Bernhard Kühn Pdf

This detailed book addresses major goals of regenerative medicine and the cardiovascular research community with techniques to replenish lost cardiomyocytes, avoid scar-associated pathology, and improve myocardial infarction (MI) outcomes. The collection begins with a section on cardiac injury models, including zebrafish, neonatal and adult mice, and pigs, and continues with sections covering culturing cardiomyocytes from different species as well as methods for labeling or manipulation of cardiac tissue for the purpose of answering questions in regeneration. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cardiac Regeneration: Methods and Protocols provides the latest models and methods used in the field of heart regeneration, designed for researchers interested in establishing these assays in their laboratories to reproduce or extend findings, and for familiarizing themselves with the field if it is new to them. The chapter “Ventricular Cryoinjury as a Model to Study Heart Regeneration in Zebrafish” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Author : Eric G. Schmuck,Peiman Hematti,Amish N. Raval
Publisher : Springer
Page : 246 pages
File Size : 40,8 Mb
Release : 2018-09-20
Category : Science
ISBN : 9783319974217

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Cardiac Extracellular Matrix by Eric G. Schmuck,Peiman Hematti,Amish N. Raval Pdf

This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM’s role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.

Author : Anwarul Hasan
Publisher : John Wiley & Sons
Page : 762 pages
File Size : 46,5 Mb
Release : 2017-06-19
Category : Science
ISBN : 9783527338634

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Tissue Engineering for Artificial Organs, 2 Volume Set by Anwarul Hasan Pdf

A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.

Author : Ravi Birla
Publisher : Springer
Page : 0 pages
File Size : 40,7 Mb
Release : 2016-10-06
Category : Science
ISBN : 3319415034

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Tissue Engineering for the Heart by Ravi Birla Pdf

This book covers the fundamentals of tissue engineering for the heart, starting with the basics of organ generation, sensors in tissue and organ fabrication, and the current state-of-the-art in stem cell engineering for the heart. With this foundation in place, the remaining chapters focus on specific aspects of the cardiovascular system, starting with heart muscle, then biological pumps, followed by bioartificial ventricles, and finally, bioartificial hearts. Throughout the course of this book, twenty-two in-depth case studies are presented. Each case study has been selected to illustrate specific design schemes for tissue and organ fabrication. This is an ideal book for upper-level undergraduate and graduate students studying tissue engineering and organ regeneration, especially those focused on cardiac regeneration. This book also: Includes twenty-two case studies that illustrate specific design schemes for engineering the heart Provides open-ended discussion questions at the end of each chapter as well as a detailed reference list to encourage further research and reading Covers the basics of organ fabrication as well as sensor technology and genetic engineering as they relate to tissue and organ fabrication

Author : Masaki Ieda,Wolfram-Hubertus Zimmermann
Publisher : Springer
Page : 0 pages
File Size : 54,8 Mb
Release : 2018-08-23
Category : Medical
ISBN : 3319858270

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Cardiac Regeneration by Masaki Ieda,Wolfram-Hubertus Zimmermann Pdf

This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Author : Erik J. Suuronen,Marc Ruel
Publisher : Unknown
Page : 340 pages
File Size : 40,7 Mb
Release : 2014-11-30
Category : Electronic
ISBN : 3319109731

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Biomaterials for Cardiac Regeneration by Erik J. Suuronen,Marc Ruel Pdf

Author : Alejandro Soto-Gutierrez,Nalu Navarro-Alvarez,Ira J. Fox
Publisher : Unknown
Page : 128 pages
File Size : 46,7 Mb
Release : 2011
Category : Biotechnology
ISBN : OCLC:1240297946

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Methods in Bioengineering by Alejandro Soto-Gutierrez,Nalu Navarro-Alvarez,Ira J. Fox Pdf

This practical book is part of the new Artech House Methods in Bioengineering series - volumes designed to offer detailed guidance on authoritative methods for addressing specific bioengineering challenges. Written and edited by recognized experts in the field, each book provides research engineers, scientists, and students with step-by-step procedures, clear examples, and effective ways to overcome problems that may be encountered. This unique volume covers in detail the basic techniques and protocols of regenerative medicine, focusing on methods for cell transplantation. You explore a wide range of critical factors, such as grown tissues, cells, laboratory-made compounds, and engineered organs. The books helps you understand the many intricate steps involved in tissue engineering, cell isolation, progenitors and stem cell differentiation, and in vivo models for assessing new strategies.

Author : Shu Q. Liu
Publisher : McGraw-Hill Education
Page : 496 pages
File Size : 53,9 Mb
Release : 2020-06-12
Category : Technology & Engineering
ISBN : 1260457648

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Cardiovascular Engineering: A Protective Approach by Shu Q. Liu Pdf

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Cardiovascular engineering principles and practices with a focus on disease prevention Aimed at advanced students taking cardiovascular, regenerative, and tissue engineering courses, Cardiovascular Engineering: A Protective Approach explores applications of protective engineering strategies and technologies to common cardiovascular disorders. A protective approach to cardiovascular engineering involves studying the naturally occurring mechanisms that protect molecules, cells, and organs from injury and dysfunction. The goal is to use this understanding to design and develop engineering-based therapeutic strategies and technologies that prevent cardiovascular injury and disease. Readers will learn the fundamental and applied aspects of cardiovascular engineering. Coverage includes: • Foundations of cardiovascular protective engineering • Development of the heart, blood vessels, and blood cells • Stem cells and regeneration • Structure and function of the heart and blood vessels • Cytokines and growth factors in cardiovascular disease • Mechanisms of disease • Systems protective mechanisms against injury • Protective engineering strategies • Systemic hypertension • Atherosclerosis and arterial aneurysms • Ischemic heart disease and ischemic stroke • Cardiomyopathies and congenital heart disease

Author : Jürgen Hescheler,Erhard Hofer
Publisher : Springer
Page : 0 pages
File Size : 44,8 Mb
Release : 2016-09-18
Category : Medical
ISBN : 9402407456

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Adult and Pluripotent Stem Cells by Jürgen Hescheler,Erhard Hofer Pdf

There is hardly an area of research developing so quickly and raising so many promises as stem cell research. Adult, embryonic and recently available induced pluripotent stem cells not only foster our understanding of differentiation of endo-, ecto- and mesodermal lineages to all organs of the body, but foremost nourish the hope that cells grown in culture can be used for regeneration of diseased organs such as the heart damaged by myocardial infarction. This book focuses on perspectives of stem cells for regenerative therapy of cardiovascular diseases. Based on the EC consortium INELPY, it reviews the field and disseminates major outcomes of this project. Thus it introduces the reader to this fascinating area of research and incorporates very recent findings interesting to the expert, spanning the field from bench to bedside. The compilation of contributions is unique as there is yet no similar comprehensive overview combining stem cell research with preclinical and clinical evaluation as well as engineering of tissue patches for transplantation. As such it will be an invaluable source of information for all researchers in the stem cell and tissue regeneration field including bioengineers as well as for all clinicians interested in regenerative therapies, especially for ischemic cardiomyopathies.