Biology Of The Mammary Gland

Author : John A. Mol,Roger A. Clegg
Publisher : Springer Science & Business Media
Page : 314 pages
File Size : 44,7 Mb
Release : 2006-04-11
Category : Science
ISBN : 9780306468322

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Biology of the Mammary Gland by John A. Mol,Roger A. Clegg Pdf

Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.

Author : Margot M. Ip,Bonnie B. Asch
Publisher : Springer Science & Business Media
Page : 366 pages
File Size : 53,6 Mb
Release : 2000-12-31
Category : Medical
ISBN : 0306463970

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Methods in Mammary Gland Biology and Breast Cancer Research by Margot M. Ip,Bonnie B. Asch Pdf

This book is a bench manual that provides in one volume all theimportant and unique technologies necessary to studies of mammarygland biology and breast cancer. The chapters are written by expertsin each area with an emphasis on nitty-gritty details that are keypoints for the successful use of a method. Sections include "in""vivo" model systems, special techniques for "in vivo"studies, "in vitro" model systems, and molecular analysis and genetransfer techniques.

Author : Jack Martinet,Louis-Marie Houdebine,Herbert-H Head
Publisher : Editions Quae
Page : 692 pages
File Size : 40,6 Mb
Release : 1999
Category : Science
ISBN : 9782738008619

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Biology of Lactation by Jack Martinet,Louis-Marie Houdebine,Herbert-H Head Pdf

A presentation of the most fundamental features of the biology of the mammary gland, a unique model of an organ capable of an abundant synthesis of proteins: endocrinology of lactation, role of prolactin, genetics and protein synthesis, immunology and the mammary gland, nutrition and dairy products. Readership: students, teachers, researchers, health and agriculture professionals. Lactation Biology was first published in French in 1993. The English version is not merely a translation: it has been updated by the author.

Author : Edmund B. Rucker
Publisher : Unknown
Page : 0 pages
File Size : 45,5 Mb
Release : 2014
Category : Breast
ISBN : 1629488534

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Mammary Glands by Edmund B. Rucker Pdf

This book is a compilation of manuscripts that encompass a breadth of information from different species including rodents, dogs, cows, goats, and sheep. Normal developmental processes are covered and anatomical features are discussed, as well as the impact and significance of environmental chemicals and epigenetics on the mammary gland. In terms of disease states, cancer and mastitis are the most impactful in the fields of human medicine and livestock management, respectively, in the context of mammary gland biology. Therefore, this book presents in depth analyses of these diseases over several chapters and different model systems. Rodent and canine cancer models are discussed, which are very relevant in understanding the roles that genes and the environment play in human breast cancer. In the livestock industry, mastitis in the dairy sector has a deep economic impact globally, and results in over a billion dollar loss annually. Several chapters are devoted towards this disease in dairy cattle, sheep and goats, with an underlying theme of generating newer detection strategies to detect infections at an earlier stage. An up-to-date description of the most important signaling pathways and mechanisms that impact both development and disease are included. A gamut of sub-disciplines are found throughout the book that covers the main aspects of anatomy, physiology, cell biology, genetics, and molecular biology in both development and diseases of the mammary gland.

Author : Margot M. Ip,Bonnie B. Asch
Publisher : Springer Science & Business Media
Page : 329 pages
File Size : 48,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461542957

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Methods in Mammary Gland Biology and Breast Cancer Research by Margot M. Ip,Bonnie B. Asch Pdf

approaches to the experimental problems that still face us in understanding this most fascinating of organs. Too many people contributed to the completion of this volume to allow acknowledg ment of all the individual efforts, but we particularly thank the reviewers whose input into the editorial process was invaluable and the authors of these chapters who revised their text, sometimes more than once, to bring it to the high standards set by the Editors. The Com mittee gratefully acknowledges the support ofVysis, Inc. , in the publication of a color figure in Chapter 19, by S. Weber-Hall and Trevor Dale. Finally, we wish to express our heartfelt appreciation to Margot Ip and Bonnie Asch, who worked long and hard to bring this volume to fruition. Margaret C. Neville for the Committee on Mammary Gland Biology Preface One of the most exciting and beneficial developments in research on mammary gland biology and breast cancer has been the influx of increased funding to support this work. This influx, which has been due primarily to the tireless efforts of breast cancer activists to gamer addi tional money from various federal and state sources, has led to a rapid expansion of research efforts by attracting numerous new investigators into the field. These new investigators include students, postdoctoral fellows, and scientists from other fields.

Author : E. Anderson,G. Heppner,W. Kidwell,Daniel Medina
Publisher : Springer Science & Business Media
Page : 519 pages
File Size : 48,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461309437

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Cellular and Molecular Biology of Mammary Cancer by E. Anderson,G. Heppner,W. Kidwell,Daniel Medina Pdf

The idea for this book arose during the 1985 Gordon Conference on "Mammary Gland Biology". New developments in the methodology of cell biology and the explosive growth of molecular biology had begun to impact upon our understanding of mammary gland growth and function. It seemed a propitious time for summarizing the current status of knowledge of the cell and molecular biology of mammary cancer and for attempting to outline future areas of concern and interest. The reviews presented here were completed by the Fall of 1986. Although new insights will surely continue to emerge, it is hoped that the material in this volume will form not only a current update but a basic core of information for future experiments. We have not attempted to cover all areas of mammary gland transformation. Those areas where recent detailed reviews are already available have been omitted. Also, the areas of normal gland development, cell ultrastructure, hormone responsiveness, chemotherapy and clinical aspects of mammary cancer have not been included. Instead, we have selected those areas where the development of new methodology, reagents and results have led to new ideas about mammary gland function and development as they are related to neoplasia.

Author : Orla M. Conneely,Christiane Otto
Publisher : Springer Science & Business Media
Page : 199 pages
File Size : 51,8 Mb
Release : 2008-03-27
Category : Science
ISBN : 3540734937

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Progestins and the Mammary Gland by Orla M. Conneely,Christiane Otto Pdf

Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed.

Author : Finian Martin,Torsten Stein,Jillian Howlin
Publisher : Methods in Molecular Biology
Page : 372 pages
File Size : 50,7 Mb
Release : 2018-11-12
Category : Medical
ISBN : 1493982125

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Mammary Gland Development: Methods and Protocols by Finian Martin,Torsten Stein,Jillian Howlin Pdf

Author : C.H. Knight,M. Peaker,C.J. Wilde
Publisher : Springer Science & Business Media
Page : 296 pages
File Size : 46,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461519737

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Intercellular Signalling in the Mammary Gland by C.H. Knight,M. Peaker,C.J. Wilde Pdf

All being done, we went to Mrs Shipmans, who is a great butter-woman; and I did see there the most of milke and cream, and the cleanest, that I ever saw in my life (29 May 1661). Among others, Sir Wm. Petty did tell me that in good earnest, he hath in his will left such parts of his estate to him that could invent such and such things -as among others, that could discover truly the way of milk coming into the breasts of a woman ... (22 March 1665). My wife tells me that she hears that my poor aunt James hath had her breast cut off here in tow- her breast having long been out of order (5 May 1665). From the Diary of Samuel Pepys, published as The Shorter Pepys (edited by R. Latham), Penguin Books (1987) The long-standing ultimate importance of research on the mammary gland is illustrated by the importance attached to cows' milk for human consumption, to human lactation and to breast cancer by Samuel Pepys and his contemporaries in the middle of the 17th century. Research has tended to develop in isolation in these three areas of continuing contemporary importance largely because in most countries, the underlying science of agricultural productivity is funded separately from the underlying science of human health and welfare.

Author : Margaret C. Neville,Charles W. Daniels
Publisher : Springer
Page : 656 pages
File Size : 53,7 Mb
Release : 1987-11-30
Category : Science
ISBN : UOM:39015012543255

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The Mammary Gland by Margaret C. Neville,Charles W. Daniels Pdf

Author : Larry K. Pickering,Ardythe L. Morrow,Guillermo M. Ruiz-Palacios,Richard J. Schanler
Publisher : Springer Science & Business Media
Page : 506 pages
File Size : 40,9 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9781475742428

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Protecting Infants through Human Milk by Larry K. Pickering,Ardythe L. Morrow,Guillermo M. Ruiz-Palacios,Richard J. Schanler Pdf

Protecting Infants through Human Milk: Advancing the Scientific Evidence provides a forum in which basic scientists, clinicians, epidemiologists, and policy makers exchange the latest findings regarding the effects of human milk and breastfeeding on infant and maternal health, thereby fostering new and promising collaborations. This volume also integrates data from animal and in vitro laboratory studies with clinical and population studies to examine human milk production and composition, the mechanisms of infant protection and/or risk from human milk feeding, and proposed interventions related to infant feeding practices. Additionally, it stimulates critical evaluation of, and advances in, the scientific evidence base and research methods, and identifies the research priorities in various areas.

Author : Edmund B. Rucker
Publisher : Nova Science Publishers
Page : 280 pages
File Size : 54,9 Mb
Release : 2014-05-14
Category : Medical
ISBN : 1629488569

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Mammary Glands by Edmund B. Rucker Pdf

This compilation of manuscripts encompass a breadth of information from different species including rodents, dogs, cows, goats, and sheep. Normal developmental processes are covered and anatomical features are discussed, as well as the impact and significance of environmental chemicals and epigenetics on the mammary gland. In terms of disease states, cancer and mastitis are the most impactful in the fields of human medicine and livestock management, respectively, in the context of mammary gland biology.

Author : Zuzana Koledova,Alexandra Van Keymeulen,Vida Vafaizadeh,Emilia Peuhu
Publisher : Frontiers Media SA
Page : 158 pages
File Size : 47,7 Mb
Release : 2020-10-27
Category : Science
ISBN : 9782889660940

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Perspectives in Mammary Gland Development and Breast Cancer Research by Zuzana Koledova,Alexandra Van Keymeulen,Vida Vafaizadeh,Emilia Peuhu Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Colin J. Wilde,Malcolm Peaker,Eleanor Taylor
Publisher : Unknown
Page : 238 pages
File Size : 50,8 Mb
Release : 1997
Category : Biological transport
ISBN : WISC:89063188734

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Biological Signalling and the Mammary Gland by Colin J. Wilde,Malcolm Peaker,Eleanor Taylor Pdf

Author : Mina Bissell,Kornelia Polyak,Jeffrey M. Rosen
Publisher : Cold Spring Harbor Perspective
Page : 0 pages
File Size : 51,8 Mb
Release : 2011
Category : Medical
ISBN : 087969906X

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The Mammary Gland as an Experimental Model by Mina Bissell,Kornelia Polyak,Jeffrey M. Rosen Pdf

Studies of mammary gland biology are critically important given the prevalence of breast cancer in the population. There are many other reasons to study this organ, however. It represents an excellent model system for research into developmental mechanisms, gene regulation, tissue organization, hormonal action, secretion, and stem cell biology, revealing general principles that can be extended to other organs and tissues. This book provides valuable lessons for all cell, developmental, and cancer biologists.