Biomaterials And Implant Biocompatibility

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Biomaterials and Implant Biocompatibility

Author : Anişoara Cîmpean,Florin Miculescu
Publisher : MDPI
Page : 420 pages
File Size : 49,5 Mb
Release : 2020-03-10
Category : Technology & Engineering
ISBN : 9783039282166

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Biomaterials and Implant Biocompatibility by Anişoara Cîmpean,Florin Miculescu Pdf

The scientific advances in life sciences and engineering are constantly challenging, expanding, and redefining concepts related to the biocompatibility and safety of medical devices. New biomaterials, new products, and new testing regimes are being introduced to scientific research practices. In order to provide clinically predictive results and to ensure a high benefit–risk ratio for patients, we need to optimize material and implant characteristics, and to adapt performance and safety evaluation practices for these innovative medical devices. Various characteristics related to materials and implant development such as raw materials composition, implant surface morphology, design, geometry, porosity, and mechanical properties need to be thoroughly characterized before evaluating the biological performance of implants. Furthermore, with the increase of regulatory demands, biological evaluation needs to ensure appropriate models and methods for each implant development stage. This book is a result of the Special Issue of Materials on "Biomaterials and Implant Biocompatibility”, which focused on the recent progress in development, material testing, and the biocompatibility and bioactivity evaluation of various materials including, but not limited to, bioceramics, biopolymers, biometals, composite materials, biomimetic materials, hybrid biomaterials, and drug/device combinations for implants and prostheses with medical applications spanning from soft to hard tissue regeneration. The book covers aspects ranging from investigations into material characterization to in vitro and in vivo testing for the assessment of biological performance of advanced, novel biomaterials and implants.

Biocompatibility and Performance of Medical Devices

Author : Jean-Pierre Boutrand
Publisher : Woodhead Publishing
Page : 586 pages
File Size : 42,5 Mb
Release : 2019-11-21
Category : Medical
ISBN : 9780081026441

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Biocompatibility and Performance of Medical Devices by Jean-Pierre Boutrand Pdf

Biocompatibility and Performance of Medical Devices, Second Edition, provides an understanding of the biocompatibility and performance tests for ensuring that biomaterials and medical devices are safe and will perform as expected in the biological environment. Sections cover key concepts and challenges faced in relation to biocompatibility in medical devices, discuss the evaluation and characterization of biocompatibility in medical devices, describe preclinical performance studies for bone, dental and soft tissue implants, and provide information on the regulation of medical devices in the European Union, Japan and China. The book concludes with a review of histopathology principles for biocompatibility and performance studies. Presents diverse insights from experts in government, industry and academia Delivers a comprehensive overview of testing and interpreting medical device performance Expanded to include new information, including sections on managing extractables, accelerating and simplifying medical device development through screening and alternative biocompatibility methods, and quality strategies which fasten device access to market

Biomaterials and Implant Biocompatibility

Author : Ani?oara Cîmpean,Florin Miculescu
Publisher : Unknown
Page : 420 pages
File Size : 53,8 Mb
Release : 2020
Category : Physics
ISBN : 3039282174

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Biomaterials and Implant Biocompatibility by Ani?oara Cîmpean,Florin Miculescu Pdf

The scientific advances in life sciences and engineering are constantly challenging, expanding, and redefining concepts related to the biocompatibility and safety of medical devices. New biomaterials, new products, and new testing regimes are being introduced to.

Biological Performance of Materials

Author : Jonathan Black
Publisher : CRC Press
Page : 526 pages
File Size : 52,6 Mb
Release : 2005-12-20
Category : Medical
ISBN : 0849339596

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Biological Performance of Materials by Jonathan Black Pdf

Bioengineers need a thorough grounding in biocompatibility - the biological performance of materials. Until now, there were no publications suitable for a neophyte in the field; prior publications were either not comprehensive or focused on rather narrow interests. Drawing on the author's 35 years of experience as a teacher, researcher, and consultant in biomaterials science and engineering (BSE), Biological Performance of Materials: Fundamentals of Biocompatibility, Fourth Edition focuses primarily on principles of biological performance at a relatively fundamental level, analyzing interactions between living organisms and nonliving materials used in medical devices - the subject that sets BSE apart as a distinct field of investigation. Following an introductory section, the book is divided into three sections: the material response to biological systems, host response to biomaterials, and test methods for determining biological response in vitro as well as in animal models and clinical settings. Supplemental "Interparts" summarize the physical properties of commonly used metallic, polymeric, and ceramic biomaterials. They also provide a guide to understanding the clinical performance of implanted biomaterials.

Biological Performance of Materials

Author : Jonathan Black
Publisher : CRC Press
Page : 484 pages
File Size : 40,7 Mb
Release : 1999-07-21
Category : Medical
ISBN : 1420051970

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Biological Performance of Materials by Jonathan Black Pdf

A balanced approach to understanding the response of living tissues and systems to manufactured biomaterials and the effect of life processes on the properties and behaviour of successful and unsuccessful biomaterials. This third edition contains a glossary of specialized terms; discussion of the emerging area of tissue engineering; more sources; and more tables to additional generic biomaterials properties.

Biomaterials

Author : Sujata V. Bhat
Publisher : Alpha Science Int'l Ltd.
Page : 298 pages
File Size : 49,5 Mb
Release : 2005
Category : Medical
ISBN : 1842652079

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Biomaterials by Sujata V. Bhat Pdf

As biomaterials are used in medical devices, providing needs in such diverse surgical disciplines as ophthalmology, cardiology, neuromuscular surgery, orthopedics, dentistry etc., they must have intimate contact with patient's tissue or body fluid providing a real physical interface, which restricts developments most seriously. This book is written for those who would like to advance their knowledge of biomaterials. The subject matter of the book is divided into twelve chapters dealing with structure and relationship of biological and man made biomaterials. The application of these materials for various medical devices and recent developments in tissue engineering has also covered.

Bio-Implant Interface

Author : J.E. Ellingsen,S.P. Lyngstadaas
Publisher : CRC Press
Page : 593 pages
File Size : 53,7 Mb
Release : 2003-04-29
Category : Medical
ISBN : 9781135508210

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Bio-Implant Interface by J.E. Ellingsen,S.P. Lyngstadaas Pdf

Achieving good clinical outcomes with implanted biomaterials depends upon achieving optimal function, both mechanical and biological, which in turn depends upon integrating advances realized in biological science, material science, and tissue engineering. As these advances push back the frontiers of biomaterial medicine , the control and patterning

Biomaterials

Author : S.V. Bhat
Publisher : Springer Science & Business Media
Page : 273 pages
File Size : 41,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401003285

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Biomaterials by S.V. Bhat Pdf

As biomaterials are used in medical devices, meeting needs in such diverse surgical disciplines as ophthalmology, cardiology, neuromuscular surgery, orthopaedics, dentistry, etc., they must have intimate contact with patient's tissue or body fluids, providing a real physical interface which seriously restricts developments. This book is written for those who would like to advance their knowledge of biomaterials. The subject matter of the book is divided into twelve chapters dealing with the structure and relationship of biological and man-made biomaterials. The application of these materials for various medical devices, and recent developments in tissue engineering, are also discussed.

Biomaterials and Engineering for Implantology

Author : Yoshiki Oshida,Takashi Miyazaki
Publisher : Walter de Gruyter GmbH & Co KG
Page : 571 pages
File Size : 48,5 Mb
Release : 2022-02-07
Category : Medical
ISBN : 9783110740134

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Biomaterials and Engineering for Implantology by Yoshiki Oshida,Takashi Miyazaki Pdf

Biomaterials are composed of metallic materials, ceramics, polymers, composites and hybrid materials. Biomaterials used in human beings require safety regulations, toxicity, allergic reaction, etc. When used as implantable materials their biological compatibility, biomechanical compatibility, and morphological compatibility must be acessed. This book explores the design and requirements of biomaterials for the use in implantology.

Handbook of Biomaterial Properties

Author : William Murphy,Jonathan Black,Garth Hastings
Publisher : Springer
Page : 676 pages
File Size : 55,6 Mb
Release : 2016-06-11
Category : Technology & Engineering
ISBN : 9781493933051

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Handbook of Biomaterial Properties by William Murphy,Jonathan Black,Garth Hastings Pdf

This book provides tabular and text data relating to normal and diseased tissue materials and materials used in medical devices. Comprehensive and practical for students, researchers, engineers, and practicing physicians who use implants, this book considers the materials aspects of both implantable materials and natural tissues and fluids. Examples of materials and topics covered include titanium, elastomers, degradable biomaterials, composites, scaffold materials for tissue engineering, dental implants, sterilization effects on material properties, metallic alloys, and much more. Each chapter author considers the intrinsic and interactive properties of biomaterials, as well as their appropriate applications and historical contexts. Now in an updated second edition, this book also contains two new chapters on the cornea and on vocal folds, as well as updated insights, data, and citations for several chapters.

Biomaterials Science

Author : Buddy D. Ratner,Allan S. Hoffman,Frederick J. Schoen,Jack E. Lemons
Publisher : Elsevier
Page : 864 pages
File Size : 41,9 Mb
Release : 2004-08-18
Category : Science
ISBN : 9780080470368

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Biomaterials Science by Buddy D. Ratner,Allan S. Hoffman,Frederick J. Schoen,Jack E. Lemons Pdf

The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials. Provides comprehensive coverage of principles and applications of all classes of biomaterials Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites Endorsed by the Society for Biomaterials

An Introduction to Tissue-Biomaterial Interactions

Author : Kay C. Dee,David A. Puleo,Rena Bizios
Publisher : John Wiley & Sons
Page : 250 pages
File Size : 55,8 Mb
Release : 2003-04-14
Category : Science
ISBN : 9780471461128

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An Introduction to Tissue-Biomaterial Interactions by Kay C. Dee,David A. Puleo,Rena Bizios Pdf

An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures. Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body’s wound-healing response is emphasized throughout. Specific topics covered include:Structure and properties of biomaterials Proteins Protein-surface interactions Blood-biomaterial interactions Inflammation and infection The immune system Biomaterial responses to implantation Biomaterial surface engineering Intimal hyperplasia and osseointegration as examples of tissue-biomaterial interactions The text also provides extensive coverage of the three pertinent interfaces between the body and the biomaterial, between the body and the living cells, and between the cells and the biomaterial that are critical in the development of tissue-engineered products that incorporate living cells within a biomaterial matrix. Ideal for a one-semester, biomedical engineering course, An Introduction to Tissue-Biomaterial Interactions provides a solid framework for understanding today’s and tomorrow’s implantable biomedical devices.

Biomaterials

Author : Joyce Y. Wong,Joseph D. Bronzino,Donald R. Peterson
Publisher : CRC Press
Page : 271 pages
File Size : 48,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781439874196

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Biomaterials by Joyce Y. Wong,Joseph D. Bronzino,Donald R. Peterson Pdf

Most current applications of biomaterials involve structural functions, even in those organs and systems that are not primarily structural in their nature, or very simple chemical or electrical functions. Complex chemical functions, such as those of the liver, and complex electrical or electrochemical functions, such as those of the brain and sense

Biomaterials

Author : Roderic S. Lakes,Joon B. Park
Publisher : Springer Science & Business Media
Page : 400 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Technology & Engineering
ISBN : 9781475721560

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Biomaterials by Roderic S. Lakes,Joon B. Park Pdf

This book is intended as a general introduction to the uses of artificial materials in the human body for the purposes of aiding healing, correcting deformities, and restoring lost function. It is an outgrowth of an undergraduate course for senior students in biomedical engineering, and it is offered as a text to be used in such courses. Topics include biocompatibility, techniques to minimize cor rosion or other degradation of implant materials, principles of materials science as it relates to the use of materials in the body, and specific uses of materials in various tissues and organs. It is expected that the student will have successively completed elementary courses in the mechanics of deformable bodies and in anatomy and physiology, and preferably also an introductory course in materials science prior to undertaking a course in biomaterials. Many quantitative examples are included as exercises for the engineering student. We recognize that many of these involve unrealistic simplifications and are limited to simple mechanical or chemical aspects of the implant problem. We offer as an apology the fact that biomaterials engineering is still to a great extent an empirical discipline that is complicated by many unknowns associated with the human body. In recognition of that fact, we have endeavored to describe both the successes and the failures in the use of materials in the human body. Also included are many photographs and illustrations of implants and devices as an aid to visualization.

Biomaterials Science and Biocompatibility

Author : Frederick H. Silver,David L. Christiansen
Publisher : Springer Science & Business Media
Page : 362 pages
File Size : 43,7 Mb
Release : 1999-10-14
Category : Science
ISBN : 0387987118

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Biomaterials Science and Biocompatibility by Frederick H. Silver,David L. Christiansen Pdf

Adopting an interdisciplinary approach to the chemistry and physics of materials, their biocompatibility, and the consequences of implantation of such devices into the human body, this text introduces readers to the principles of polymer science and the study of metals, ceramics and composites, and also to the basic biology required to understand the nature of the host-transplant interface. Topics covered include the macromolecular components of cells and tissues, self-assembly processes, biological cascade systems, microscopic structure of cells and tissues, immunology, transplantation biology, and the pathobiology of wound healing. The materials science section includes the structures and properties of polymers, metals, ceramics and composites, and the processes for forming materials as well as the pathobiology of devices. The final two chapters deal with tissue engineering and the relations between the biology of cells and tissue transplantation, and the engineering of tissue replacements using passaged cells.