Biomaterials For Vasculogenesis And Angiogenesis

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Biomaterials for Vasculogenesis and Angiogenesis

Saeid Kargozar,Masoud Mozafari
Biomaterials for Vasculogenesis and Angiogenesis Book PDF

Author : Saeid Kargozar,Masoud Mozafari
Publisher : Woodhead Publishing
Page : 522 pages
File Size : 54,7 Mb
Release : 2022-05-19
Category : Medical
ISBN : 9780128218686

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Biomaterials for Vasculogenesis and Angiogenesis by Saeid Kargozar,Masoud Mozafari Pdf

Biomaterials for Angiogenesis and Vasculogenesis covers the application of materials designed to encourage new blood vessel formation. Angiogenesis and vasculogenesis play an important role in tissue engineering and regenerative medicine research by promoting vascular networks inside engineered tissues and thereby increasing tissue healing and regeneration. However, researchers are faced with the challenge of finding suitable materials for improving angiogenesis and vascular formation in assays. This book reviews a broad range of biomaterials for the promotion of blood vessel genesis, from polymers and bioactive glass, to nanomaterial scaffolds and 3D angiogenic constructs. In addition, the book covers a variety of applications for biomaterials in tissue repair and regeneration, including cardiovascular regeneration, liver tissue engineering and much more. It will serve as a detailed reference for researchers in academia and industry, working in the fields of biomedical science and engineering, materials science, regenerative medicine and translational medicine. Introduces readers to the molecular and cellular basis of angiogenesis and vasculogenesis Helps researchers find suitable biomaterials to promote angiogenesis in engineered tissues and assays Describes a range of biomaterials and their properties, including glass-ceramics, nano-carriers, polymers, and more

Vasculogenesis and Angiogenesis

Dan Simionescu,Agneta Simionescu
Vasculogenesis and Angiogenesis Book PDF

Author : Dan Simionescu,Agneta Simionescu
Publisher : BoD – Books on Demand
Page : 242 pages
File Size : 50,9 Mb
Release : 2011-11-07
Category : Medical
ISBN : 9789533078823

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Vasculogenesis and Angiogenesis by Dan Simionescu,Agneta Simionescu Pdf

Vasculogenesis is the process of new blood vessel formation during embryonic development of the cardiovascular system. This is followed by formation of a vascular tree and finally the cardiovascular system with the myriad of blood vessels that nourish all tissues and organs. Angiogenesis, on the other hand is the process by which new blood vessels take shape from existing blood vessels by "sprouting" of endothelial cells thus expanding the vascular tree. Both scenarios are based on activation, migration, proliferation and maturation of unique precursor cells. The study of blood vessel formation is an essential component of embryonic development, congenital malformations, degenerative diseases, inflammation and cancer and thus has widespread appeal to the biomedical field. Moreover, scientists are now harnessing this information for the purpose of building living blood vessel substitutes for replacement of diseased arteries and veins. This book highlights novel advances in the field of vasculogenesis and angiogenesis, including embryogenesis and development, regulation of progenitor cells, cancer and blood vessel regeneration. We consider this book a good initial source of information for graduate students, medical students and scientists interested in the intricacies of blood vessel formation, maturation, disease and replacement.

New Frontiers in Angiogenesis

Reza Forough
New Frontiers in Angiogenesis Book PDF

Author : Reza Forough
Publisher : Springer Science & Business Media
Page : 226 pages
File Size : 41,8 Mb
Release : 2006-01-11
Category : Medical
ISBN : 1402043260

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New Frontiers in Angiogenesis by Reza Forough Pdf

New Frontiers in Angiogenesis is a fresh and unconventional look at the field of angiogenesis. It focuses on provocative and cutting-edge topics in the field of angiogenesis. Each chapter will take the reader along on a journey into uncharted territories of angiogenesis. The volume starts with a comprehensive overview of the field and continues with topics that have been minimally explored. The topics deal with dynamics of vasculogenesis using imaging techniques, bone marrow-derived endothelial cell precursors as potential therapeutic tools, regulation of post-angiogenic vessel regression, vascular mimicry, design and construction of artificial vessels, bioengineering of angiogenesis, and lymphangiogenesis recapitulating angiogenesis in health and disease states. Each chapter is written by leading experts of the subjects. It is hoped that this volume will challenge all of us interested in the field of angiogenesis and cardiovascular biology, in particular those in academia and industries, to think "outside the box" and explore angiogenesis from a fresh angle. It is hoped that New Frontiers in Angiogenesis is thought provoking and serve as a road map for discovering new findings to help betterments of human health.

Biophysical Regulation of Vascular Differentiation and Assembly

Sharon Gerecht
Biophysical Regulation of Vascular Differentiation and Assembly Book PDF

Author : Sharon Gerecht
Publisher : Springer Science & Business Media
Page : 254 pages
File Size : 44,7 Mb
Release : 2011-01-06
Category : Science
ISBN : 9781441978356

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Biophysical Regulation of Vascular Differentiation and Assembly by Sharon Gerecht Pdf

Because of their ability to differentiate and develop into functional vasculature, stem cells hold tremendous promise for therapeutic applications. However, the scientific understanding and the ability to engineer these cellular systems is still in its early stages, and must advance significantly for the therapeutic potential of stem cells to be realized. Stem cell differentiation and function are exquisitely tuned by their microenvironment. This book will provide a unique perspective of how different aspect of the vasculature microenvironment regulates differentiation and assembly. Recent efforts to exploits modern engineering techniques to study and manipulate various biophysical cues will be described including: oxygen tension during adult and embryonic vasculogenesis (Semenza and Zandstra), extracellular matrix during tube morphogenesis and angiogenesis (Wirtz, Davis, Ingber), surface topography and modification (Chen and Gerecht), shear stress and cyclic strain effect on vascular assembly and maturation (Vunjak-Novakovic and Niklason), and three dimensional space for angio-andvasculogensis (Ferreria and Fischbach).

Mechanical and Chemical Signaling in Angiogenesis

Cynthia Reinhart-King
Mechanical and Chemical Signaling in Angiogenesis Book PDF

Author : Cynthia Reinhart-King
Publisher : Springer Science & Business Media
Page : 280 pages
File Size : 54,5 Mb
Release : 2012-09-12
Category : Medical
ISBN : 9783642308550

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Mechanical and Chemical Signaling in Angiogenesis by Cynthia Reinhart-King Pdf

A worthy addition to Springer’s series of Studies in Mechanobiology, Tissue Engineering and Biomaterials, this volume focuses on the latest techniques, with contributions from angiogenesis experts in engineering, cell and developmental biology, and chemistry.

Tissue Engineering for Artificial Organs, 2 Volume Set

Anwarul Hasan
Tissue Engineering for Artificial Organs 2 Volume Set Book PDF

Author : Anwarul Hasan
Publisher : John Wiley & Sons
Page : 762 pages
File Size : 41,9 Mb
Release : 2017-06-19
Category : Science
ISBN : 9783527338634

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Tissue Engineering for Artificial Organs, 2 Volume Set by Anwarul Hasan Pdf

A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.

Vascularization for Tissue Engineering and Regenerative Medicine

Wolfgang Holnthoner,Andrea Banfi,James Kirkpatrick,Heinz Redl
Vascularization for Tissue Engineering and Regenerative Medicine Book PDF

Author : Wolfgang Holnthoner,Andrea Banfi,James Kirkpatrick,Heinz Redl
Publisher : Springer
Page : 0 pages
File Size : 44,7 Mb
Release : 2021-06-09
Category : Technology & Engineering
ISBN : 3319545841

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Vascularization for Tissue Engineering and Regenerative Medicine by Wolfgang Holnthoner,Andrea Banfi,James Kirkpatrick,Heinz Redl Pdf

This reference work presents the basic principles of angiogenesis induction, including the roles of signaling factors such as hypoxia-inducible factors, biophysical stimulation and angiogenic cells. The book also covers lymphogenesis induction. Both the established fundamentals in the field as well as new trends in the vascularization of engineered tissues are discussed. These include pre-vascularization strategies using preparation of channeled scaffolds and preparation of decellularized blood vessel trees, approaches to inducing formation of microvasculature and approaches to inducing the growth of vascular networks. The authors expand on these concepts with current studies of dual-level approaches to engineer vascularized tissue composites. The book concludes with a discussion of current clinical approaches and the use of vascular grafts in the context of providing clinical practice with new tissue engineering strategies.

Angiogenesis Assays

Carolyn A. Staton,Claire Lewis,Roy Bicknell
Angiogenesis Assays Book PDF

Author : Carolyn A. Staton,Claire Lewis,Roy Bicknell
Publisher : John Wiley & Sons
Page : 410 pages
File Size : 46,9 Mb
Release : 2007-01-11
Category : Medical
ISBN : 9780470029343

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Angiogenesis Assays by Carolyn A. Staton,Claire Lewis,Roy Bicknell Pdf

Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.

Biosynthetic Polymers for Medical Applications

Laura Poole-Warren,Penny Martens,Rylie Green
Biosynthetic Polymers for Medical Applications Book PDF

Author : Laura Poole-Warren,Penny Martens,Rylie Green
Publisher : Elsevier
Page : 358 pages
File Size : 44,9 Mb
Release : 2015-11-23
Category : Medical
ISBN : 9781782421139

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Biosynthetic Polymers for Medical Applications by Laura Poole-Warren,Penny Martens,Rylie Green Pdf

Biosynthetic Polymers for Medical Applications provides the latest information on biopolymers, the polymers that have been produced from living organisms and are biodegradable in nature. These advanced materials are becoming increasingly important for medical applications due to their favorable properties, such as degradability and biocompatibility. This important book provides readers with a thorough review of the fundamentals of biosynthetic polymers and their applications. Part One covers the fundamentals of biosynthetic polymers for medical applications, while Part Two explores biosynthetic polymer coatings and surface modification. Subsequent sections discuss biosynthetic polymers for tissue engineering applications and how to conduct polymers for medical applications. Comprehensively covers all major medical applications of biosynthetic polymers Provides an overview of non-degradable and biodegradable biosynthetic polymers and their medical uses Presents a specific focus on coatings and surface modifications, biosynthetic hydrogels, particulate systems for gene and drug delivery, and conjugated conducting polymers

Nutritional Epigenomics

Anonim
Nutritional Epigenomics Book PDF

Author : Anonim
Publisher : Academic Press
Page : 478 pages
File Size : 45,8 Mb
Release : 2019-07-20
Category : Medical
ISBN : 9780128173107

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Nutritional Epigenomics by Anonim Pdf

Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. Empowers the reader to employ nutritional epigenomics approaches in their own research Discusses the latest topics in nutritional epigenomics in the regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and disease Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies

Biochemical Basis and Therapeutic Implications of Angiogenesis

Jawahar Mehta,Naranjan S. Dhalla
Biochemical Basis and Therapeutic Implications of Angiogenesis Book PDF

Author : Jawahar Mehta,Naranjan S. Dhalla
Publisher : Springer Science & Business Media
Page : 536 pages
File Size : 41,5 Mb
Release : 2013-03-29
Category : Medical
ISBN : 9781461458579

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Biochemical Basis and Therapeutic Implications of Angiogenesis by Jawahar Mehta,Naranjan S. Dhalla Pdf

Angiogenesis is a highly complex phenomenon where new blood vessels are formed for the supply of oxygen and nutrients in different organs of the body. It plays a critical role in both physiological processes such as growth and development as well as pathological processes including cancer and different types of tumors. Angiogenesis is also essential for the regeneration and survival of cells in several disease conditions such as ischemic heart disease (myocardial infarction), atherosclerosis, brain injury (stroke) and diabetes. Since the mechanisms of angiogenesis are organ specific and differ among various diseases, it is proposed to devote one section of this book to the development of angiogenesis in some selected diseases such as cancer, ischemic heart disease, atherosclerosis, diabetes and stroke. It is pointed out that extensive research work in this regard has been carried out in the area of cancer and heart disease, whereas relatively less attention has been paid to studying angiogenesis in other disease conditions.

Post-Genomic Cardiology

José Marín-García
Post Genomic Cardiology Book PDF

Author : José Marín-García
Publisher : Academic Press
Page : 935 pages
File Size : 51,9 Mb
Release : 2014-05-09
Category : Medical
ISBN : 9780124046429

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Post-Genomic Cardiology by José Marín-García Pdf

In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome, comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA. Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs

Advances in Metallodrugs

Shahid Ul-Islam,Athar Adil Hashmi,Salman Ahmad Khan
Advances in Metallodrugs Book PDF

Author : Shahid Ul-Islam,Athar Adil Hashmi,Salman Ahmad Khan
Publisher : John Wiley & Sons
Page : 432 pages
File Size : 53,7 Mb
Release : 2020-07-08
Category : Science
ISBN : 9781119640424

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Advances in Metallodrugs by Shahid Ul-Islam,Athar Adil Hashmi,Salman Ahmad Khan Pdf

This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering.

Silk-Based Biomaterials for Tissue Engineering, Regenerative and Precision Medicine

Subhas C. Kundu,Rui L. Reis
Silk Based Biomaterials for Tissue Engineering Regenerative and Precision Medicine Book PDF

Author : Subhas C. Kundu,Rui L. Reis
Publisher : Elsevier
Page : 908 pages
File Size : 46,9 Mb
Release : 2023-12-15
Category : Technology & Engineering
ISBN : 9780323960168

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Silk-Based Biomaterials for Tissue Engineering, Regenerative and Precision Medicine by Subhas C. Kundu,Rui L. Reis Pdf

Silk-based Biomaterials for Tissue Engineering, Regenerative and Precision Medicine, Second Edition is a must-have reference, providing comprehensive coverage of silk-based biomaterials and their importance in translational uses and biomedicine. This new edition considers the progress made in the past eight years, featuring many new chapters, including a discussion of cutting-edge fabrication methods and techniques, new and improved blends/composites, and an expanded range of applications in tissue engineering, regenerative and precision medicine. The book holistically reviews the types, structure and properties, processing methods, and specific biomedical applications for silk-based biomaterials. This will be a vital resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics interested in biomaterials, regenerative, and precision medicine. Covers all key silk biomaterial types, including mulberry, Bombyx mori and nonmulberry/wild silk protein fibroins, sericins and spider silk, as well as their composite blends and various structures and scaffold platforms Describes the cutting-edge processing techniques for each silk type, from traditional to nonconventional methods, such as using ionic liquids and engineering nanofibers and other biomedical matrices Explores a range of applications in tissue engineering and regenerative and precision medicine, including bioprinting, bioelectronics and medical devices

Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials

Munmaya Mishra
Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials Book PDF

Author : Munmaya Mishra
Publisher : CRC Press
Page : 2856 pages
File Size : 55,6 Mb
Release : 2017-08-16
Category : Medical
ISBN : 9781351651202

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Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials by Munmaya Mishra Pdf

The Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials presents new and selected content from the 11-volume Biomedical Polymers and Polymeric Biomaterials Encyclopedia. The carefully culled content includes groundbreaking work from the earlier published work as well as exclusive online material added since its publication in print. A diverse and global team of renowned scientists provide cutting edge information concerning polymers and polymeric biomaterials. Acknowledging the evolving nature of the field, the encyclopedia also features newly added content in areas such as tissue engineering, tissue repair and reconstruction, and biomimetic materials.