Biomaterials Medical Devices And Tissue Engineering An Integrated Approach

Author : Frederick Silver
Publisher : Springer Science & Business Media
Page : 318 pages
File Size : 50,6 Mb
Release : 1993-11-30
Category : Technology & Engineering
ISBN : 0412412608

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Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach by Frederick Silver Pdf

are then selected and must meet the general 'biocompatibility' require ments. Prototypes are built and tested to include biocompatibility evalua tions based on ASTM standard procedures. The device is validated for sterility and freedom from pyrogens before it can be tested on animals or humans. Medical devices are classified as class I, II or III depending on their invasiveness. Class I devices can be marketed by submitting notification to the FDA. Class II and III devices require either that they show equivalence to a device marketed prior to 1976 or that they receive pre-marketing approval. The time from device conception to FDA approval can range from months (class I device) to in excess of ten years (class III device). Therefore, much planning is necessary to pick the best regulatory approach. 2. Wound Dressings and Skin Replacement 2.1 Introduction Wounds to the skin are encountered every day. Minor skin wounds cause some pain, but these wounds will heal by themselves in time. Even though many minor wounds heal effectively without scarring in the absence of treatment, they heal more rapidly if they are kept clean and moist. Devices such as Band-Aids are used to assist in wound healing. For deeper wounds, a variety of wound dressings have been developed including cell cultured artificial skin. These materials are intended to promote healing of skin damaged or removed as a result of skin grafting, ulceration, burns, cancer excision or mechanical trauma.

Author : Frederick H. Silver
Publisher : Unknown
Page : 0 pages
File Size : 44,6 Mb
Release : 1994
Category : Biomedical materials
ISBN : OCLC:28749249

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Biomaterials, Medical Devices, and Tissue Engineering by Frederick H. Silver Pdf

Author : F.H. Silver
Publisher : Springer Science & Business Media
Page : 310 pages
File Size : 43,8 Mb
Release : 2012-12-06
Category : Technology & Engineering
ISBN : 9789401107358

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Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach by F.H. Silver Pdf

are then selected and must meet the general 'biocompatibility' require ments. Prototypes are built and tested to include biocompatibility evalua tions based on ASTM standard procedures. The device is validated for sterility and freedom from pyrogens before it can be tested on animals or humans. Medical devices are classified as class I, II or III depending on their invasiveness. Class I devices can be marketed by submitting notification to the FDA. Class II and III devices require either that they show equivalence to a device marketed prior to 1976 or that they receive pre-marketing approval. The time from device conception to FDA approval can range from months (class I device) to in excess of ten years (class III device). Therefore, much planning is necessary to pick the best regulatory approach. 2. Wound Dressings and Skin Replacement 2.1 Introduction Wounds to the skin are encountered every day. Minor skin wounds cause some pain, but these wounds will heal by themselves in time. Even though many minor wounds heal effectively without scarring in the absence of treatment, they heal more rapidly if they are kept clean and moist. Devices such as Band-Aids are used to assist in wound healing. For deeper wounds, a variety of wound dressings have been developed including cell cultured artificial skin. These materials are intended to promote healing of skin damaged or removed as a result of skin grafting, ulceration, burns, cancer excision or mechanical trauma.

Author : Yitzhak Rosen,Noel Elman
Publisher : CRC Press
Page : 328 pages
File Size : 53,8 Mb
Release : 2012-06-06
Category : Medical
ISBN : 9781439804049

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Biomaterials Science by Yitzhak Rosen,Noel Elman Pdf

"This book is essential when designing, developing and studying biomedical materials.... provides an excellent review—from a patient, disease, and even genetic point of view—of materials engineering for the biomedical field. ... This well presented book strongly insists on how the materials can influence patients’ needs, the ultimate drive for biomedical engineering. ...[presents an] Interesting and innovative review from a patient focus perspective—the book emphasizes the importance of the patients, which is not often covered in other biomedical material’s books." —Fanny Raisin-Dadre, BioInteractions Ltd., Berkshire, England Going far beyond the coverage in most standard books on the subject, Biomaterials Science: An Integrated Clinical and Engineering Approach offers a solid overview of the use of biomaterials in medical devices, drug delivery, and tissue engineering. Combining discussion of materials science and engineering perspectives with clinical aspects, this book emphasizes integration of clinical and engineering approaches. In particular, it explores various applications of biomaterials in fields including tissue engineering, neurosurgery, hemocompatibility, BioMEMS, nanoparticle-based drug delivery, dental implants, and obstetrics/gynecology. The book engages those engineers and physicians who are applying biomaterials at various levels to: Increase the rate of successful deployment of biomaterials in humans Lower the side-effects of such a deployment in humans Accumulate knowledge and experience for improving current methodologies Incorporate information and understanding relevant to future challenges, such as permanent artificial organ transplants Using a variety of contributors from both the clinical and engineering sides of the fields mentioned above, this book stands apart by emphasizing a need for the often lacking approach that integrates these two equally important aspects.

Author : Raymond H. W. Lam,Weiqiang Chen
Publisher : Springer
Page : 379 pages
File Size : 45,5 Mb
Release : 2019-08-16
Category : Medical
ISBN : 9783030242374

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Biomedical Devices by Raymond H. W. Lam,Weiqiang Chen Pdf

This textbook provides essential knowledge for biomedical product development, including material properties, fabrication processes and design techniques for different applications, as well as process design and optimization. This book is multidisciplinary and readers can learn techniques to apply acquired knowledge for various applications of biomedical design. Further, this book encourages readers to discover and convert newly reported technologies into products and services for the future development of biomedical applications. This is an ideal book for upper-level undergraduate and graduate students, engineers, technologists, and researchers working in the area of biomedical engineering and manufacturing. This book also: Provides a comprehensive set of fundamental knowledge for engineering students and entry level engineers to design biomedical devices Offers a unique approach to manufacturing of biomedical devices by integrating and formulating different considerations in process design tasks into optimization problems Provides a broad range of application examples to guide readers through the thinking process of designing and manufacturing biomedical devices, from basic understanding about the requirements and regulations to a set of manufacturing parameters

Author : Michael N. Helmus
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 45,5 Mb
Release : 2003-01-31
Category : Technology & Engineering
ISBN : 0306476908

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Biomaterials in the Design and Reliability of Medical Devices by Michael N. Helmus Pdf

This book highlights the responsibility of medical device designers and engineers to eliminate sites of failure and to test devices to demonstrate their ultimate safety and efficacy. It also evaluates biomaterials and their properties as related to the design and reliability of medical devices. The principles that are described are readily applicable to the biomaterial scaffolds used for generating tissue-engineered constructs.

Author : Sujata K. Bhatia
Publisher : Springer Science & Business Media
Page : 350 pages
File Size : 54,9 Mb
Release : 2011-11-10
Category : Technology & Engineering
ISBN : 9781461410805

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Engineering Biomaterials for Regenerative Medicine by Sujata K. Bhatia Pdf

Regeneration of tissues and organs remains one of the great challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement. Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress is made possible by advances in materials science, polymer chemistry, and molecular biology. This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. The latest methods for regulating the biological and chemical composition of biomaterials are described, together with techniques for modulating mechanical properties of engineered constructs. Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility. The book culminates in a discussion of the clinical applications of regenerative medicine. By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic. The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and will also enable physicians to understand novel biomaterials that are emerging in the clinic. This integrated approach also gives engineering students a sense of the excitement and relevance of materials science in the development of novel therapeutic strategies.

Author : Roger Narayan
Publisher : Springer Science & Business Media
Page : 573 pages
File Size : 52,9 Mb
Release : 2009-06-20
Category : Technology & Engineering
ISBN : 9780387848723

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Biomedical Materials by Roger Narayan Pdf

Biomedical Materials provides a comprehensive discussion of contemporary biomaterials research and development. Highlighting important topics associated with Engineering, Medicine and Surgery, this volume reaches a wide scope of professionals, researchers and graduate students involved with biomaterials. A pedagogical writing style and structure provides readers with an understanding of the fundamental concepts necessary to pursue research and industrial work on biomaterials, including characteristics of biomaterials, biological processes, biocompatibility, and applications of biomaterials in implants and medical instruments. Written by leading researchers in the field, this text book takes readers to the forefront of biomedical materials development, providing them with a taste of how the field is changing, while also serving as a useful reference to physicians and engineers.

Author : Nesrin Hasirci,Vasif Hasirci
Publisher : Springer Science & Business Media
Page : 388 pages
File Size : 48,7 Mb
Release : 2010-02-23
Category : Medical
ISBN : 9780306485848

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Biomaterials by Nesrin Hasirci,Vasif Hasirci Pdf

Biomaterials: From Molecules to Engineered Tissue gives examples of the application areas of biomaterials involving molecules at one end of the spectrum and finished devices in the other. It covers molecular approaches as well as molecules functional in preparing and modifying biomaterials, medical devices and systems, tissue engineering and artificial organs. Chapters on biomedical informatics and ethics complement the design and production aspects with their contribution in informatics and ethical concerns of biomedical research. This is a reference book for the advanced graduate student eager to learn the biomaterials area and for all researchers working in medicine, pharmacy, engineering and basic sciences in universities, hospitals, and industry involved in biomaterials and biomedical device production.

Author : Kevin Healy,Dietmar W. Hutmacher,David W. Grainger,C. James Kirkpatrick
Publisher : Elsevier
Page : 4865 pages
File Size : 49,7 Mb
Release : 2017-05-18
Category : Technology & Engineering
ISBN : 9780081006924

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Comprehensive Biomaterials II by Kevin Healy,Dietmar W. Hutmacher,David W. Grainger,C. James Kirkpatrick Pdf

Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Author : William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski
Publisher : Academic Press
Page : 1612 pages
File Size : 40,6 Mb
Release : 2020-05-23
Category : Medical
ISBN : 9780128161388

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Biomaterials Science by William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski Pdf

The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for most chapters

Author : Hossein Hosseinkhani
Publisher : John Wiley & Sons
Page : 324 pages
File Size : 44,9 Mb
Release : 2023-04-17
Category : Technology & Engineering
ISBN : 9783527347469

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Biomedical Engineering by Hossein Hosseinkhani Pdf

An exploration of materials processing and engineering technology across a wide range of medical applications The field of biomedical engineering has played a vital role in the progression of medical development technology. Biomedical Engineering: Materials, Technology, and Applications covers key aspects of the field—from basic concepts to advanced level research for medical applications. The book stands as a source of inspiration for research on materials as well as their development and practical application within specialized industries. It begins with a discussion of what biomedical engineering is and concludes with a final chapter on the advancements of biomaterials technology in medicine. Offers comprehensive coverage of topics, including biomaterials, tissue engineering, bioreceptor interactions, and various medical applications Discusses applications in critical industries such as biomedical diagnosis, pharmaceutics, drug delivery, cancer detection, and more Serves as a reference for those in scientific, medical, and academic fields Biomedical Engineering takes an interdisciplinary look at how biomedical science and engineering technology are integral to developing novel approaches to major problems, such as those associated with disease diagnosis and drug delivery. By covering a full range of materials processing and technology-related subjects, it shares timely information for biotechnologists, material scientists, biophysicists, chemists, bioengineers, nanotechnologists, and medical researchers.

Author : Murugan Ramalingam,Ziyad Haidar,Seeram Ramakrishna,Hisatoshi Kobayashi,Youssef Haikel
Publisher : John Wiley & Sons
Page : 325 pages
File Size : 43,5 Mb
Release : 2012-04-03
Category : Science
ISBN : 9781118311981

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Integrated Biomaterials in Tissue Engineering by Murugan Ramalingam,Ziyad Haidar,Seeram Ramakrishna,Hisatoshi Kobayashi,Youssef Haikel Pdf

This book acts as a self-contained resource for understanding the current technological advancement of biomaterials towards tissue engineering applications. It covers impact of biomaterials at different length scales such as macro/micro/nano/ level and offers extensive discussion on cell-biomaterial interactions with illustrative examples. This resource offer a multi-disciplinary approach for the adaptability of integrated biomaterials in tissue repair and reconstruction.

Author : Joao F. Mano
Publisher : John Wiley & Sons
Page : 872 pages
File Size : 49,8 Mb
Release : 2013-02-08
Category : Science
ISBN : 9783527652297

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Biomimetic Approaches for Biomaterials Development by Joao F. Mano Pdf

Biomimetics, in general terms, aims at understanding biological principles and applying them for the development of man-made tools and technologies. This approach is particularly important for the purposeful design of passive as well as functional biomaterials that mimic physicochemical, mechanical and biological properties of natural materials, making them suitable, for example, for biomedical devices or as scaffolds for tissue regeneration. The book comprehensively covers biomimetic approaches to the development of biomaterials, including: an overview of naturally occurring or nature inspired biomaterials; an in-depth treatment of the surface aspects pivotal for the functionality; synthesis and self-assembly methods to prepare devices to be used in mineralized tissues such as bone and teeth; and preparation of biomaterials for the controlled/ sustained release of bioactive agents. The last part reviews the applications of bioinspired materials and principles of design in regenerative medicine such as in-situ grown bone or cartilage as well as the biomimetic techniques for soft tissue engineering. The comprehensive scope of this book makes it a must-have addition to the bookshelf of everyone in the fields of Materials Science/Engineering, Nanotechnologies / Nanosciences, Medical Sciences, Biochemistry, Polymer Chemistry, and Biomedical Engineering.

Author : Cuie Wen
Publisher : Woodhead Publishing
Page : 606 pages
File Size : 49,8 Mb
Release : 2020-08-20
Category : Technology & Engineering
ISBN : 9780081029664

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Metallic Biomaterials Processing and Medical Device Manufacturing by Cuie Wen Pdf

Metallic Biomaterials Processing and Medical Device Manufacturing details the principles and practices of the technologies used in biomaterials processing and medical device manufacturing. The book reviews the main categories of metallic biomaterials and the essential considerations in design and manufacturing of medical devices. It bridges the gap between the designing of biomaterials and manufacturing of medical devices including requirements and standards. Main themes of the book include, manufacturing, coatings and surface modifications of medical devices, metallic biomaterials and their mechanical behaviour, degradation, testing and characterization, and quality controls, standards and FDA regulations of medical devices. The leading experts in the filed discuss the requirements, challenges, recent progresses and future research directions in the processing of materials and manufacturing of medical devices. Metallic Biomaterials Processing and Medical Device Manufacturing is ideal for those working in the disciplines of materials science, manufacturing, biomedical engineering, and mechanical engineering. Reviews key topics of biomaterials processing for medical device applications including metallic biomaterials and their mechanical behavior, degradation, testing and characterization Bridges the gap between biomaterials design and medical device manufacturing Discusses the quality controls, standards, and FDA requirements for biomaterials and medical devices