Biophysics Of The Cell Surface

Author : Roland Glaser,David Gingell
Publisher : Springer Science & Business Media
Page : 366 pages
File Size : 50,9 Mb
Release : 2013-03-07
Category : Science
ISBN : 9783642744716

Get Book

Biophysics of the Cell Surface by Roland Glaser,David Gingell Pdf

It is common practice to publish conference papers in books or monograph series. This gives some advantage to those who did not have the opportunity to attend the meetings, but it irritates and disappoints others who may have hoped for a set of closely related reviews. With this book we have tried to find a compromise. It presents a selection from the topics which have been discussed in a series of inter national symposia entitled "Biophysics of Cell Surface", held in 1976, 1978, 1981, 1985 and 1988 in the GDR, and subsequently published in the journal STUDIA BIOPHYSICA (volumes 56, 74, 90, 110, 1271. Nearly all the contributors to this book participated in one or more of the meetings. We hope that our choice of topics selected for this book manages to reflect the variety and interest of the broad range of subjects which fall within the scope of membrane biophysics, without taking on the randomness of a scientific car-boot sale. We would like to express our thanks to all colleagues and organ~ isations who helped to realize the conferences and particularly this book. financial support for the symposia of 1985 and 1988 was provided by the IUPAB. A number of topics, reflected in this book, resulted in internat ional cooperations, supported by various organisations. We are especially grateful for the support of UNESCO research project on biophysicS in this respect. The European Bureau (ROSTE) of UNESCO supported the editorial work of this book.

Author : Richard M. Epand,Jean-Marie Ruysschaert
Publisher : Springer
Page : 219 pages
File Size : 48,9 Mb
Release : 2017-09-25
Category : Science
ISBN : 9789811062445

Get Book

The Biophysics of Cell Membranes by Richard M. Epand,Jean-Marie Ruysschaert Pdf

This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well.

Author : Mohammad Ashrafuzzaman,Jack A. Tuszynski
Publisher : Springer Science & Business Media
Page : 190 pages
File Size : 52,7 Mb
Release : 2012-08-28
Category : Science
ISBN : 9783642161056

Get Book

Membrane Biophysics by Mohammad Ashrafuzzaman,Jack A. Tuszynski Pdf

Physics, mathematics and chemistry all play a vital role in understanding the true nature and functioning of biological membranes, key elements of living processes. Besides simple spectroscopic observations and electrical measurements of membranes we address in this book the phenomena of coexistence and independent existence of different membrane components using various theoretical approaches. This treatment will be helpful for readers who want to understand biological processes by applying both simple observations and fundamental scientific analysis. It provides a deep understanding of the causes and effects of processes inside membranes, and will thus eventually open new doors for high-level pharmaceutical approaches towards fighting membrane- and cell-related diseases.

Author : Gajanan V. Sherbet
Publisher : Unknown
Page : 328 pages
File Size : 55,6 Mb
Release : 1978
Category : Science
ISBN : UOM:39015004337385

Get Book

The Biophysical Characterisation of the Cell Surface by Gajanan V. Sherbet Pdf

Author : G. Benga,H. Baum,F.A. Kummerow
Publisher : Springer Science & Business Media
Page : 265 pages
File Size : 41,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461382744

Get Book

Membrane Processes by G. Benga,H. Baum,F.A. Kummerow Pdf

The burgeoning interest in biomembranes in recent years has been such that "membranology" is now virtuMtyasubject in its own right, cutting vertically, as it were, through the strata of conventional disciplines from mathematics and physics, through chemistry, to biology. The very scope of the topic is thus so daunting that it is tempting to treat it only at one stratum of this hierarchy, be it the biophysics of phospholipid bilayers or the biochemistry of interactions at the cell surface. Such an approach is entirely valid, particularly among specialists with common interests. However, this approach does present a distorted perspective to the newcomer to the field, and, more significantly, it fails to stimulate cross fertil ization of ideas among workers at the various disciplinary levels. For example, as in all areas of molecular biology, the clinicians are frequently unaware of the contributions to their problems that might be made by the application of more basic knowledge and techniques. Conversely, biochemists or biophysicists may be ignorant of the existing practical problems to which they might address their expertise.

Author : Nick Sperelakis
Publisher : Academic Press
Page : 998 pages
File Size : 45,5 Mb
Release : 2012-01-11
Category : Science
ISBN : 9780123877383

Get Book

Cell Physiology Source Book by Nick Sperelakis Pdf

Cell Physiology Source Book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The 4e contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, and synaptic transmission. Authored by leading researchers in the field Clear, concise, and comprehensive coverage of all aspects of cellular physiology, from fundamental concepts to more advanced topics Full color illustrations

Author : Hongda Wang,Guohui Li
Publisher : Springer
Page : 421 pages
File Size : 43,6 Mb
Release : 2017-11-21
Category : Science
ISBN : 9789811068232

Get Book

Membrane Biophysics by Hongda Wang,Guohui Li Pdf

This book highlights recent advances in and diverse techniques for exploring the plasma membrane’s structure and function. It starts with two chapters reviewing the history of membrane research and listing recent advances regarding membrane structure, such as the semi-mosaic model for red blood cell membranes and the protein layer-lipid-protein island model for nucleated tissue cell membranes. It subsequently focuses on the localization and interactions of membrane components, dynamic processes of membrane transport and transmembrane signal transduction. Classic and cutting-edge techniques (e.g. high-resolution atomic force microscopy and super-resolution fluorescence microscopy) used in biophysics and chemistry are presented in a very comprehensive manner, making them useful and accessible to both researchers in the field and novices studying cell membranes. This book provides readers a deeper understanding of the plasma membrane’s organization at the single molecule level and opens a new way to reveal the relationship between the membrane’s structure and functions, making it essential reading for researchers in various fields.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 46,8 Mb
Release : 2017
Category : Biophysics
ISBN : 9811062455

Get Book

The Biophysics of Cell Membranes by Anonim Pdf

"This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well."--

Author : Claudia Tanja Mierke
Publisher : Springer Nature
Page : 919 pages
File Size : 44,9 Mb
Release : 2020-10-30
Category : Science
ISBN : 9783030585327

Get Book

Cellular Mechanics and Biophysics by Claudia Tanja Mierke Pdf

This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.

Author : Christopher J. Fielding
Publisher : John Wiley & Sons
Page : 294 pages
File Size : 48,5 Mb
Release : 2006-12-13
Category : Science
ISBN : 9783527607501

Get Book

Lipid Rafts and Caveolae by Christopher J. Fielding Pdf

This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail. Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include: Historical background Distinct structures and functions Structural basis Signaling Viral entry and virion budding Cholesterol transport Caveolins Lipid shells Cell polarity and intracellular trafficking Cancer cells Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.

Author : Armin Kargol
Publisher : Morgan & Claypool Publishers
Page : 117 pages
File Size : 41,6 Mb
Release : 2019-03-29
Category : Science
ISBN : 9781643274102

Get Book

Introduction to Cellular Biophysics, Volume 1 by Armin Kargol Pdf

All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or entire organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What does the cell consist of? Where are its organelles? What function does each organelle fulfil? From a chemists' point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, one of the main questions is the physical movement of all these molecules between organelles within the cell, as well as their exchange with the extracellular medium. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and that in turn leads to the biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfil its function as a part of a larger organ or organism. This book is an inventory of physical transport processes occurring in cells while the second volume will be a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

Author : B. Kahan
Publisher : Springer
Page : 280 pages
File Size : 51,6 Mb
Release : 2012-11-26
Category : Science
ISBN : 1468472445

Get Book

The Cell Surface by B. Kahan Pdf

The Conference "Chemical and Immunologic Approaches to the Cell Surface" was organized as a multifaceted interaction between scientists representing various disCiplines impinging on membrane bio logy. In many instances, this broad mixture of investigators yielded quite unusual scientific associations and interesting new dimensions to old prob lems, as the workers came to appreciate the advallces, the shortcomings, and the hurdles of each area. Structural concepts of the membrane--the nature, orientation, and inter-relationship of components--are emerging primarily from work on erythrocytes. Our understanding of surface biology demands reconstruc tion from the meager, but rapidly emerging, structural information. The excitement of membrane research depends in no small part on the concept that membranes are not static crystalline structures but rather dynamic systems with variable interrelationships between mUltiple components and phases, reflecting external environmental and internal cellular events. Modulation of the membrane can be readily studied in systems where dis crete pertubation is introduced into the surface structure by stimulation with mitogens or reactions of immunoglobulins, reSUlting in wide-ranging effects. Examination of sequential changes such as patching and capping, in intact cells or in artificially reconstituted lipide, or lipide-protein, membrane systems probably represent useful iatrogeniC probes to mimic genuine in vivo biophysical phenomena related to the mobility, cooperative ly and constraint of surface components.

Author : Mohammad Ashrafuzzaman
Publisher : Springer
Page : 386 pages
File Size : 42,5 Mb
Release : 2018-04-12
Category : Science
ISBN : 9783319774657

Get Book

Nanoscale Biophysics of the Cell by Mohammad Ashrafuzzaman Pdf

Macroscopic cellular structures and functions are generally investigated using biological and biochemical approaches. But these methods are no longer adequate when one needs to penetrate deep into the small-scale structures and understand their functions. The cell is found to hold various physical structures, molecular machines, and processes that require physical and mathematical approaches to understand and indeed manipulate them. Disorders in general cellular compartments, perturbations in single molecular structures, drug distribution therein, and target specific drug-binding, etc. are mostly physical phenomena. This book will show how biophysics has revolutionized our way of addressing the science and technology of nanoscale structures of cells, and also describes the potential for manipulating the events that occur in them.

Author : Armin Kargol
Publisher : Unknown
Page : 108 pages
File Size : 44,9 Mb
Release : 2019-12-13
Category : Electronic
ISBN : 1643277588

Get Book

Introduction to Cellular Biophysics, Volume 2 by Armin Kargol Pdf

All living matter is comprised of cells, which are small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. Cells are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What the cells consist of? Where are its organelles? What function each organelle fulfils? From a chemists' point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. From a physics standpoint, however, some of the fundamental questions involve the physical movement of all these molecules between organelles within the cell, their exchange with the extracellular medium, as well as electrical phenomena resulting from such transport. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and various electrical effects, and that, in turn, leads to the biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfil its function as a part of a larger organ or organism. The first volume of this book is an inventory of physical transport processes occurring in cells, and this volume provides a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

Author : Marek Cebecauer,David Holowka
Publisher : Frontiers Media SA
Page : 150 pages
File Size : 53,5 Mb
Release : 2018-02-07
Category : Electronic
ISBN : 9782889454099

Get Book

Molecular Organization of Membranes: Where Biology Meets Biophysics by Marek Cebecauer,David Holowka Pdf

Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed of lipids and proteins influencing each other. Local membrane composition and properties define its molecular organisation and, in this way, regulate the function of all associated molecules. Therefore, studying interactions of components, biophysical properties and overall membrane dynamics provides essential information on its function in the context of cell activities. Such knowledge can contribute to biomedical fields such as pharmacology, immunology, neurobiology and many others. The goal of the Research Topic entitled ‘Molecular organisation of membranes: where biology meets biophysics’ was to provide a comprehensive platform for publishing articles, reviews and opinions focused on membrane organisation and the forces behind its heterogeneous and dynamic structure. We collected 11 works which cover topics as diverse as general membrane organisation models, membrane trafficking and signalling regulation, biogenesis of caveolae, protein-lipid interactions and the importance of membrane-associated tetraspanins networks. The prevalent theme was the existence of membrane nanodomains. To this point, new emerging technologies are presented which own the power to bring a novel insight on how membrane nanodomains are formed and maintained and what is their function. We believe that the collection of works in this Research Topic brings forward some important questions which will stimulate further research in this difficult but exciting field.