Bioresorbable Polymers For Biomedical Applications

Author : Giuseppe Perale,Jöns Hilborn
Publisher : Woodhead Publishing
Page : 628 pages
File Size : 49,6 Mb
Release : 2016-08-24
Category : Technology & Engineering
ISBN : 9780081002667

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Bioresorbable Polymers for Biomedical Applications by Giuseppe Perale,Jöns Hilborn Pdf

Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine provides readers with an overview of bioresorbable polymeric materials in the biomedical field. A useful resource for materials scientists in industry and academia, offering information on the fundamentals and considerations, synthesis and processing, and the clinical and R and D applications of bioresorbable polymers for biomedical applications. Focuses on biomedical applications of bioresorbable polymers Features a comprehensive range of topics including fundamentals, synthesis, processing, and applications Provides balanced coverage of the field with contributions from academia and industry Includes clinical and R and D applications of bioresorbable polymers for biomedical applications

Author : Declan Devine
Publisher : Walter de Gruyter GmbH & Co KG
Page : 241 pages
File Size : 44,9 Mb
Release : 2019-04-15
Category : Medical
ISBN : 9783110640663

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Bioresorbable Polymers by Declan Devine Pdf

Bioresorbable implants can be processed via conventional polymer processing methods such as extrusion, injection and compressing moulding, solvent spinning or casting. This book addresses issues and highlights recent advances in the use of biodegradable polymers. It is intended for researchers utilizing biodegradable polymers in areas from tissue engineering to controlled release of active pharmaceuticals, as well as industrial processors.

Author : Declan M Devine
Publisher : Smithers Rapra
Page : 254 pages
File Size : 41,9 Mb
Release : 2017-04-10
Category : Science
ISBN : 9781911088097

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Bioresorbable Polymers and their Biomedical Applications by Declan M Devine Pdf

Bioresorbable or biodegradable polymers are commonly used in various biomedical applications. The application of bioresorbable polymers in the biomedical sector has been widely exploited by immobilising suturing thread with an analgesic or antibacterial drugs, and the development of bioresorbable vascular scaffolds, wound-healing and intravenous drug-delivery devices. Furthermore, biodegradable polymers have been investigated as a replacement for metallic orthopaedic devices due to their precise control of material composition and microstructure. These polymers are eliminated from the body via dissolution, assimilation and excretion through metabolic pathways. The hydrolysing process breaks down the polymer into smaller units and its degradation products are excreted by means of the citric acid cycle or by direct renal excretion with no residual side effects.Processing of bioresorbable implants can be achieved via conventional polymer processing methods such as extrusion, injection and compressing moulding, solvent spinning or casting. However, special consideration must be given when processing these materials because heat can cause a reduction in molecular weight due to the hydrolysing of bonds. In addition, overheating can depolymerise the polymer and, as a result, monomers can have a plasticising effect on the polymer. Recently, alternative approaches utilising rapid prototyping and micro-/nanofabrication processes have been employed.This book addresses these issues and highlights recent advances in the biomedical field that have being enabled by the use of biodegradable polymers. This book is designed as a reference guide for academic researchers utilising biodegradable polymers in a range of areas from tissue engineering to controlled release of active pharmaceuticals, through to industry-based processors of biodegradable polymers.

Author : Declan Devine
Publisher : Walter de Gruyter GmbH & Co KG
Page : 152 pages
File Size : 40,7 Mb
Release : 2019-04-15
Category : Medical
ISBN : 9783110640571

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Bioresorbable Polymers by Declan Devine Pdf

Bioresorbable implants can be processed via conventional polymer processing methods such as extrusion, injection and compressing moulding, solvent spinning or casting. This book addresses issues and highlights recent advances in the use of biodegradable polymers. It is intended for researchers utilizing biodegradable polymers in areas from tissue engineering to controlled release of active pharmaceuticals, as well as industrial processors.

Author : Rui L. Reis,Nuno M. Neves,Joao F. Mano,Manuela E. Gomes,Alexandra P. Marques,Helena S. Azevedo
Publisher : Elsevier
Page : 832 pages
File Size : 41,8 Mb
Release : 2008-08-15
Category : Technology & Engineering
ISBN : 9781845694814

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Natural-Based Polymers for Biomedical Applications by Rui L. Reis,Nuno M. Neves,Joao F. Mano,Manuela E. Gomes,Alexandra P. Marques,Helena S. Azevedo Pdf

Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering. The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility. Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. Examines the sources, processing and properties of natural based polymers for biomedical applications Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine

Author : Mike Jenkins
Publisher : Elsevier
Page : 236 pages
File Size : 41,8 Mb
Release : 2007-08-06
Category : Technology & Engineering
ISBN : 9781845693640

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Biomedical Polymers by Mike Jenkins Pdf

Given the rapid development and use of biomaterials, it is becoming increasingly important to understand the structure, processing and properties of biomedical polymers and their medical applications. With its distinguished editor and team of international contributors, Biomedical Polymers reviews the latest research on this important group of biomaterials. The book discusses natural, synthetic, biodegradable and non bio-degradable polymers and their applications. Chapters review polymeric scaffolds for tissue engineering and drug delivery systems, the use of polymers in cell encapsulation, their role as replacement materials for heart valves and arteries, and their applications in joint replacement. The book also discusses the use of polymers in biosensor applications. Biomedical polymers is an essential reference for scientists and all those concerned with the development and use of this important group of biomaterials Reviews the latest research in this important group of biomaterials Discusses natural, synthetic, biodegradable and non-biodegradable polymers and their applications Examines the use of biomedical polymers in such areas as drug delivery systems and cell encapsulation

Author : Deepak Verma,Manunya Okhawilai,Kheng-Lim Goh,Seeram Ramakrishna,Pooria Pasbakhsh,Mohit Sharma
Publisher : Elsevier
Page : 538 pages
File Size : 47,5 Mb
Release : 2023-12-01
Category : Technology & Engineering
ISBN : 9780443189166

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Bioresorbable Polymers and their Composites by Deepak Verma,Manunya Okhawilai,Kheng-Lim Goh,Seeram Ramakrishna,Pooria Pasbakhsh,Mohit Sharma Pdf

Bioresorbable Polymers and their Composites: Characterization and Fundamental Processing for Pharmaceutical and Medical Device Development provides a holistic view of these unique materials and their usage in a range of biomedical applications. The book is evenly divided between fundamentals, processing methods and modeling approaches, and includes detailed coverage of a variety of applications, such as drug delivery, medical devices and wound healing. Key aspects including biocompatibility, biodegradability and toxicology are also thoroughly covered, enabling the reader to be fully informed when fabricating and utilizing their selected bioresorbable polymer. This book is an interdisciplinary and important reference for researchers in the fields of materials science, biomedical engineering, pharmaceutical science and regenerative medicine, as well as R&D groups in the development of medical devices. Introduces the reader to various processing and modeling techniques for bioresorbable polymers, including electrospinning, molecular and finite element modeling Covers a range of key bioresorbable composites, such as PCL, PLA/PLLA and PHA/PHB/PHBV Explores a wide selection of biomedical applications of bioresorbable polymers, from tissue engineering and stents, to biosensors and medical devices/implants

Author : Xiang Cheng Zhang
Publisher : Woodhead Publishing
Page : 476 pages
File Size : 54,7 Mb
Release : 2016-09-22
Category : Medical
ISBN : 9780081003930

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Science and Principles of Biodegradable and Bioresorbable Medical Polymers by Xiang Cheng Zhang Pdf

Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers. Provides a practical guide to the fundamentals, synthesis, and processing of bioresorbable polymers in medicine Contains comprehensive coverage of material properties, including unique insights into modeling degradation Written by an eclectic mix of international authors with experience in academia and industry

Author : Tatiana G. Volova,Yuri S. Vinnik,Ekaterina I. Shishatskaya,Nadejda M. Markelova,Gennady E. Zaikov
Publisher : CRC Press
Page : 396 pages
File Size : 44,9 Mb
Release : 2017-04-21
Category : Medical
ISBN : 9781315341811

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Natural-Based Polymers for Biomedical Applications by Tatiana G. Volova,Yuri S. Vinnik,Ekaterina I. Shishatskaya,Nadejda M. Markelova,Gennady E. Zaikov Pdf

This new book presents the authors’ biomedical studies of natural degradable biopolymers (polyhydroxyalkanoates [PHAs]) and discusses the demand for medical-grade materials and modern trends, focusing on the present status and future potential of PHAs. The authors present and summarize their most important results and findings obtained during the last few years in experimental studies and clinical trials of PHAs at the Institute of Biophysics Siberian Branch of Russian Academy of Science.

Author : Severian Dumitriu
Publisher : CRC Press
Page : 1192 pages
File Size : 46,7 Mb
Release : 2001-11-29
Category : Science
ISBN : 0203904672

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Polymeric Biomaterials, Revised and Expanded by Severian Dumitriu Pdf

Offering nearly 7000 references-3900 more than the first edition-Polymeric Biomaterials, Second Edition is an up-to-the-minute source for plastics and biomedical engineers, polymer scientists, biochemists, molecular biologists, macromolecular chemists, pharmacists, cardiovascular and plastic surgeons, and graduate and medical students in these disciplines. Completely revised and updated, it includes coverage of genetic engineering, synthesis of biodegradable polymers, hydrogels, and mucoadhesive polymers, as well as polymers for dermacosmetic treatments, burn and wound dressings, orthopedic surgery, artificial joints, vascular prostheses, and in blood contacting systems.

Author : Liqun Yang,Jianshe Hu,Shuai Jiang,Hongli Mao,Himansu Sekhar Nanda
Publisher : Frontiers Media SA
Page : 140 pages
File Size : 43,8 Mb
Release : 2022-07-13
Category : Science
ISBN : 9782889765713

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Biodegradable Polymers for Biomedical Applications by Liqun Yang,Jianshe Hu,Shuai Jiang,Hongli Mao,Himansu Sekhar Nanda Pdf

Author : Sangamesh G. Kum bar,Cato Laurencin,Meng Deng
Publisher : Newnes
Page : 421 pages
File Size : 40,5 Mb
Release : 2014-01-21
Category : Technology & Engineering
ISBN : 9780123972903

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Natural and Synthetic Biomedical Polymers by Sangamesh G. Kum bar,Cato Laurencin,Meng Deng Pdf

Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future

Author : Abraham J. Domb,Neeraj Kumar
Publisher : John Wiley & Sons
Page : 594 pages
File Size : 50,5 Mb
Release : 2011-05-12
Category : Technology & Engineering
ISBN : 9781118015803

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Biodegradable Polymers in Clinical Use and Clinical Development by Abraham J. Domb,Neeraj Kumar Pdf

This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.

Author : Stoyko Fakirov
Publisher : John Wiley & Sons
Page : 368 pages
File Size : 53,8 Mb
Release : 2015-04-06
Category : Technology & Engineering
ISBN : 9783527656974

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Biodegradable Polyesters by Stoyko Fakirov Pdf

Collating otherwise hard-to-get and recently acquired knowledge in one work, this is a comprehensive reference on the synthesis, properties, characterization, and applications of this eco-friendly class of plastics. A group of internationally renowned researchers offer their first-hand experience and knowledge, dealing exclusively with those biodegradable polyesters that have become increasingly important over the past two decades due to environmental concerns on the one hand and newly-devised applications in the biomedical field on the other. The result is an unparalleled overview for the industrial chemist and materials scientist, as well as for developers and researchers in industry and academia alike.

Author : Zheng Zhang,Ophir Ortiz,Ritu Goyal,Joachim Kohn
Publisher : Elsevier Inc. Chapters
Page : 368 pages
File Size : 40,7 Mb
Release : 2013-12-05
Category : Technology & Engineering
ISBN : 9780128076750

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Handbook of Polymer Applications in Medicine and Medical Devices by Zheng Zhang,Ophir Ortiz,Ritu Goyal,Joachim Kohn Pdf

The design and development of tissue-engineered products has benefited from many years of clinical utilization of a wide range of biodegradable polymers. Newly developed biodegradable polymers and modifications of previously developed biodegradable polymers have enhanced the tools available for creating clinically important tissue-engineering applications. Insights gained from studies of cell-matrix interactions, cell-cell signaling, and organization of cellular components, are placing increased demands on medical implants to interact with the patient’s tissue in a more biologically appropriate fashion. Whereas in the twentieth century biocompatibility was largely equated with eliciting no harmful response, the biomaterials of the twenty first century will have to elicit tissue responses that support healing or regeneration of the patient’s own tissue. This chapter surveys the universe of those biodegradable polymers that may be useful in the development of medical implants and tissue-engineered products. Here, we distinguish between biologically derived polymers and synthetic polymers. The materials are described in terms of their chemical composition, breakdown products, mechanism of breakdown, mechanical properties, and clinical limitations. Also discussed are product design considerations in processing of biomaterials into a final form (e.g., gel, membrane, matrix) that will effect the desired tissue response.