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Author : Konrad Emil Bloch
Publisher : Unknown
Page : 261 pages
File Size : 50,8 Mb
Release : 1994
Category : Biochemistry
ISBN : OCLC:1040012122
Author : Konrad Bloch
Publisher : Yale University Press
Page : 280 pages
File Size : 52,7 Mb
Release : 1994-01-01
Category : Science
ISBN : 0300070551
In this fascinating book, the Nobel Prize-winning scientist Konrad Bloch muses on various aspects of biochemistry, explaining the chemical basis for many biological phenomena. Drawing on his own experiences as well as on colorful anecdotes about the work of other scientists, Bloch presents a new way of looking at the world and a revealing glimpse into the ways that scientific discoveries are made and problems are solved. Bloch begins with a charming essay on why--despite the fact that peroxide had not yet been invented--there are so many blonde women in Italian Renaissance paintings. He then considers, among other topics, some important biochemical processes that were discovered because of contamination; the importance of trial and error in biochemical research; the explanation of lactose intolerance in adults and practices for avoiding it; why the choice of animal models is important for medical research (and how the author injected himself with extracts of the tubercle bacilli to study the pathology of tuberculosis); and why the exotic nine-banded armadillo has unique potential for use in many areas of medical and biological investigations. He concludes with thoughts on biochemistry's origin and future.
Author : Albert Rothenberg
Publisher : Oxford University Press, USA
Page : 249 pages
File Size : 42,7 Mb
Release : 2015
Category : Psychology
ISBN : 9780199988792
This is the first empirical investigation of scientific creativity based on research interviews with living Nobel laureates in physics, chemistry, and physiology or medicine, whose formulations are compared to those of a control group of engineering faculty members. Findings were that three cognitive creative processes described herein - janusian, homospatial, and sep-con articulation - as well as strong motivation, passion, and other accompanying emotions, were responsible for creative breakthroughs leading to outstanding scientific discoveries in the Nobel laureate group.
Author : Reginald H. Garrett
Publisher : Cengage Learning Canada Inc
Page : 128 pages
File Size : 54,5 Mb
Release : 2015-05-11
Category : Science
ISBN : 9780176726737
Biochemistry 1st Canadian edition guides students through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world from a unique Canadian context. Biochemistry is a living science that touches every aspect of our lives and this book ensures students are made aware of the significance and interdisciplinary nature of this subject; questions posed at the beginning of each chapter and new “Why it Matters” boxes grab interest and tap into students inner ‘scientist’ answering why and how topics are relevant and important, “Human Biochemistry” features highlight how biochemistry affects our bodies, as well as “Critical Developments” sections focus on various types of drug design. Highlighting the most current research topics such as mRNA turnover and microRNA, as well as Canadian researchers and institutions, the 1st Canadian edition of Biochemistry will help students master the concepts of biochemistry and gain new insight into this dynamic science.
Author : Antony Mackinlay
Publisher : Xlibris Corporation
Page : 188 pages
File Size : 41,9 Mb
Release : 2022-10-26
Category : Science
ISBN : 9781669832249
Languages are like organisms, they do not appear by spontaneous creation, they evolve, and so it is with the particular terminology of biochemistry which, as I document here, largely derives from Latin and Ancient Greek root words. In the early part of the 19th century, when chemistry had shaken off the shackles of alchemy, new elements, new compounds, new techniques were discovered that needed names. It was the classical languages, Greek and Latin, to which these early scientists turned. As chemical approaches were applied to biology, much molecular terminology has also derived from these languages. In this book the common technical terms encountered in biochemistry and related subjects are defined and their derivation from root words in Latin and Ancient Greek explained.
Author : Nick Lane
Publisher : W. W. Norton & Company
Page : 275 pages
File Size : 52,8 Mb
Release : 2022-07-12
Category : Science
ISBN : 9780393651492
From the renowned biochemist and author of The Vital Question, an illuminating inquiry into the Krebs cycle and the origins of life. “Nick Lane’s exploration of the building blocks that underlie life’s big fundamental questions—the origin of life itself, aging, and disease—have shaped my thinking since I first came across his work. He is one of my favorite science writers.”—Bill Gates What brings the Earth to life, and our own lives to an end? For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight —how the same simple chemistry gives rise to life and causes our demise. Lane is among the vanguard of researchers asking why the Krebs cycle, the “perfect circle” at the heart of metabolism, remains so elusive more than eighty years after its discovery. Transformer is Lane’s voyage, as a biochemist, to find the inner meaning of the Krebs cycle—and its reverse—why it is still spinning at the heart of life and death today. Lane reveals the beautiful, violent world within our cells, where hydrogen atoms are stripped from the carbon skeletons of food and fed to the ravenous beast of oxygen. Yet this same cycle, spinning in reverse, also created the chemical building blocks that enabled the emergence of life on our planet. Now it does both. How can the same pathway create and destroy? What might our study of the Krebs cycle teach us about the mysteries of aging and the hardest problem of all, consciousness? Transformer unites the story of our planet with the story of our cells—what makes us the way we are, and how it connects us to the origin of life. Enlivened by Lane’s talent for distilling and humanizing complex research, Transformer offers an essential read for anyone fascinated by biology’s great mysteries. Life is at root a chemical phenomenon: this is its deep logic.
Author : Julian Chela-Flores,François Raulin
Publisher : Springer Science & Business Media
Page : 377 pages
File Size : 43,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401150569
Leading researchers in the area of the origin, evolution and distribution of life in the universe contributed to Exobiology: Matter, Energy, and Information in the Origin and Evolution of Life in the Universe. This volume provides a review of this interdisciplinary field. In 50 chapters many aspects that contribute to exobiology are reviewed by 90 authors. These include: historical perspective of biological evolution; cultural aspects of exobiology, cosmic, chemical and biological evolution, molecular biology, geochronology, biogeochemistry, biogeology, and planetology. Some of the current missions are discussed. Other subjects in the frontier of exobiology are reviewed, such as the search for planets outside the solar system, and the possible manifestation of intelligence in those new potential environments. The SETI research effort is well represented in this general overview of exobiology. This book is the proceedings of the Fifth Trieste Conference on Chemical Evolution that took place in September 1997. The volume is dedicated to the memory of Nobel Laureate Abdus Salam who suggested the initiation of the Trieste conferences on chemical evolution and the origin of life. Audience: Graduate students and researchers in the many areas of basic, earth, and life sciences that contribute to the study of chemical evolution and the origin, evolution and distribution of life in the universe.
Author : Anonim
Publisher : Yale University Press
Page : 814 pages
File Size : 46,7 Mb
Release : 2024-06-11
Category : Biochemistry
ISBN : 0300153597
In this book a distinguished scientist-historian offers a critical account of how biochemistry and molecular biology emerged as major scientific disciplines from the interplay of chemical and biological ideas and practice. Joseph S. Fruton traces the historical development of these disciplines from antiquity to the present time, examines their institutional settings, and discusses their impact on medical, pharmaceutical, and agricultural practice.
Author : Muriel Gargaud,Purificación López-Garcìa,Hervé Martin
Publisher : Cambridge University Press
Page : 547 pages
File Size : 55,8 Mb
Release : 2011-01-06
Category : Science
ISBN : 9781139494595
Devoted to exploring questions about the origin and evolution of life in our Universe, this highly interdisciplinary book brings together a broad array of scientists. Thirty chapters assembled in eight major sections convey the knowledge accumulated and the richness of the debates generated by this challenging theme. The text explores the latest research on the conditions and processes that led to the emergence of life on Earth and, by extension, perhaps on other planetary bodies. Diverse sources of knowledge are integrated, from astronomical and geophysical data, to the role of water, the origin of minimal life properties and the oldest traces of biological activity on our planet. This text will not only appeal to graduate students but to the large body of scientists interested in the challenges presented by the origin of life, its evolution, and its possible existence beyond Earth.
Author : Ellen Tremper
Publisher : University of Virginia Press
Page : 308 pages
File Size : 52,6 Mb
Release : 2006
Category : Literary Criticism
ISBN : 0813925215
Have you ever wondered why there are so many "dumb blonde" jokes--always about women? Or how Ivanhoe's childhood love, the"flaxen Saxon" Rowena, morphed into Marilyn Monroe? Between that season in 1847 when readers encountered Becky Sharp playing the vengeful Clytemnestra--about to plunge a dagger into Agamemnon--and the sunny moment in 1932 when moviegoers watched Clark Gable plunge Jean Harlow's platinum-tressed head into a rain barrel, the playing field for women and men had leveled considerably. But how did the fairy-tale blonde, that placid, pliant girl, become the "tomato upstair," as Monroe styled herself in The Seven Year Itch? In I'm No Angel: The Blonde in Fiction and Film, Ellen Tremper shows how, at its roots, the image of the blonde was remodeled by women writers in the nineteenth century and actors in the twentieth to keep pace with the changes in real women's lives. As she demonstrates, through these novels and performances, fair hair and its traditional attributes--patience, pliancy, endurance, and innocence--suffered a deliberate alienation, which both reflected and enhanced women's personal and social freedoms essential to the evolution of modernity. From fiction to film, the active, desiring, and sometimes difficult women who disobeyed, manipulated, and thwarted their fellow characters mimicked and furthered women's growing power in the world. The author concludes with an overview of the various roles of the blonde in film from the 1960s to the present and speculates about the possible end of blond dominance. An engaging and lively read, I'm No Angel will appeal to a general audience interested in literary and cinematic representations of the blonde, as well as to scholars in Victorian, women's, and film studies.
Author : Chemical Heritage Foundation
Publisher : Chemical Heritage Foundation
Page : 28 pages
File Size : 43,8 Mb
Release : 1997
Category : Reference
ISBN : 0941901181
An introductory guide that is designed particularly for teachers and their students, but is useful in many other contexts. This new edition lists reference works; histories of science and technology; histories of the chemical sciences and industries including company histories; autobiographies and biographies; edited classical texts; and journals.
Author : Jie Jack Li
Publisher : OUP USA
Page : 220 pages
File Size : 50,8 Mb
Release : 2009-04-03
Category : Medical
ISBN : 9780195323573
Prologue. 1. Cholesterol. 2. Genesis of Statins. 3. Merck's Triumph. 4. Discovery of Lipitor. 5. Development of Lipitor. 6. To Market, To Market. 7. Baycol, Crestor, and Drugs beyond Statins. 8. Reflections. Appendix. Trademarks of the Drugs. Bibliography and Notes. Index.
Author : Eugene H. Cordes
Publisher : Oxford University Press
Page : 280 pages
File Size : 50,5 Mb
Release : 2020-04-20
Category : Science
ISBN : 9780190080471
The discovery of novel drugs that fill unmet medical needs is important for the health and well-being of people everywhere. However, the general public knows too little about the pathways through which basic research discoveries are translated into products that protect or restore human health. In the second edition of Hallelujah Moments, Eugene H. Cordes reveals the processes and pitfalls on the route from the laboratory bench to the bedside. These are adventure stories in which wit and grit created several of the most important drugs in human medicine. This new edition adds four new tales of drug discovery: for therapy of cancer, hepatitis C, HIV/AIDS, and for weight control. The stories emphasize the integration of basic research in academe and applied research in the pharmaceutical industry and introduce the key scientists. In each case, success resulted from imagination, risk-taking, problem solving, and perseverance. Cordes shares his firsthand knowledge of the drug-discovery world, having spent a long and distinguished career in both academic and industrial settings. The eleven drug discovery tales take the reader from concept to clinic for some of the most important drugs in human health including the statins, ACE inhibitors, antibiotics, avermectins, Januvia, and Taxol. These stories offer exciting insights into the fascinating world of drug discovery.
Author : Joseph D. Robinson
Publisher : Oxford University Press
Page : 469 pages
File Size : 41,9 Mb
Release : 2001-05-17
Category : Medical
ISBN : 9780198031451
Synaptic transmission plays a central role in the nervous system as the mechanism that allows for chemical and electrical communication between cells and thus connects discrete elements into the functioning whole. This is a broad account of anatomical, biochemical, embryological, medical, pathological, pharmacological, and physiological studies on synaptic transmission during the hundred years beginning in 1890. During this century, the process of synaptic transmission came to be recognized not only as the most fundamental neurophysiological process, but also as a seat of pathological changes, and as the predominant site of action for drugs used to treat a wide range of psychiatric and neurological disorders. At the same time, research from these various disciplines was transformed into a new and unifying field, neuroscience. The course of these investigations reveals ingenious experiments, powerful new techniques, and imaginative insights. The author describes broadly who did what, when, where, and how (and, in cases where it is apparent, why) and uses experimental results and interpretations to display the evolutionary course to our current understanding of how nerve cells communicate: the basic principle of neural functioning. The book will be of interest to basic and clinical neuroscientists, pharmacologists, and physiologists, to historians and philosophers of the life sciences and medicine, and to their respective students.
Author : Ole G. Mouritsen
Publisher : Springer Science & Business Media
Page : 276 pages
File Size : 49,8 Mb
Release : 2006-03-30
Category : Science
ISBN : 9783540270768
Presents a multi-disciplinary perspective on the physics of life and the particular role played by lipids and the lipid-bilayer component of cell membranes. Emphasizes the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Shows how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nano-technology and biomedicine are also described.