Bone Cancer

Author : Dominique Heymann
Publisher : Elsevier
Page : 736 pages
File Size : 45,9 Mb
Release : 2014-09-04
Category : Medical
ISBN : 9780124167285

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Bone Cancer by Dominique Heymann Pdf

Bone Cancer, Second Edition comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Second Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with key chapters from the first edition, and offers numerous new chapters describing the new concepts of bone cancer biology and therapy, for both primary bone tumors as well as bone metastases. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases – from bench to bedside: development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases. Presents a comprehensive, translational source for all aspects of primary bone cancer and bone metastases in one reference work Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays

Author : Dominique Heymann
Publisher : Academic Press
Page : 472 pages
File Size : 50,7 Mb
Release : 2010
Category : Juvenile Nonfiction
ISBN : 012374895X

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Bone Cancer by Dominique Heymann Pdf

Clear presentation by bone biologists of the cellular and molecular mechanisms underlying bone tumors and bone cancer metastasis as well as the genomic and proteomic assays used in detecting cancer within given organ systems Clear presentation by oncologists and radiologists of how histopathology, imaging, and pain monitoring can lead to new therapeutic approaches Benefit Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of bone cancer issues, as opposed to searching through thousands of journal articles.-

Author : Dominique Heymann
Publisher : Academic Press
Page : 1080 pages
File Size : 52,9 Mb
Release : 2021-09-23
Category : Medical
ISBN : 9780323899901

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Bone Cancer by Dominique Heymann Pdf

Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside, Third Edition comprehensively investigates key discoveries in the field of bone biology. New aspects of bone cancer biology are treated in new chapters covering exosomes, autophagy, and metabolism. These have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Third Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with 40% new material. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases. This revision opens the door to myeloma with two short chapters dedicated to this bone-associated disease. Covers the broad field of bone sarcomas and bone metastases from basic research to clinical approaches Presents comprehensive and translational overview of biological and clinical aspects of bone cancers, discussing pathophysiology from genetic and molecular levels using the most recent evidence Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays

Author : WHO Classification of Tumours Editorial Board
Publisher : WHO Classification of Tumours
Page : 0 pages
File Size : 42,5 Mb
Release : 2020
Category : Medical
ISBN : 9283245024

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Soft Tissue and Bone Tumours by WHO Classification of Tumours Editorial Board Pdf

PLEASE NOTE: Text has been accidentally deleted from page 54 of this book. Please refer to the corrigenda (PDF file) posted on the Stylus Publishing web site or email [email protected] for an updated, printable page. ****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** Soft Tissue and Bone Tumours is the third volume in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. This volume will be of particular interest to pathologists, oncologists, surgeons, and epidemiologists who manage or research soft tissue and bone tumours. Sections are included on all recognized neoplasms of the soft tissue and bone, as well as on genetic tumour syndromes affecting these sites. Since the previous edition, there have been changes based on recent molecular and genetic information, with impact on clinical practice.

Author : R. Lor Randall
Publisher : Springer
Page : 368 pages
File Size : 51,6 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781461456629

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Metastatic Bone Disease by R. Lor Randall Pdf

Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and bio targeting. The heart of the book presents oncological approaches (supportive, radiation and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text and redefine an integrated approach to patient care. Taken together, Metastatic Bone Disease is an excellent resource for orthopedic surgeons and cancer specialists alike.

Author : Frederick L, Greene,David L. Page,Irvin D. Fleming,April G. Fritz,Charles M. Balch,Daniel G. Haller,Monica Morrow
Publisher : Springer Science & Business Media
Page : 386 pages
File Size : 47,9 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781475736564

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AJCC Cancer Staging Manual by Frederick L, Greene,David L. Page,Irvin D. Fleming,April G. Fritz,Charles M. Balch,Daniel G. Haller,Monica Morrow Pdf

The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms.

Author : Friedhelm Raue
Publisher : Springer Science & Business Media
Page : 211 pages
File Size : 40,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642850738

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Hypercalcemia of Malignancy by Friedhelm Raue Pdf

Hypercalcemia is the most common life-threatening metabolic disorder associated with cancer. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. With a better understanding of the pathophysiology of this condition and the development of new potent drugs, capable of inhibiting bone resorption, especially bisphosphonates, the clinician will be more successful in correcting hypercalcemia in the great majority of patients.

Author : Heather Hasan
Publisher : The Rosen Publishing Group, Inc
Page : 66 pages
File Size : 50,9 Mb
Release : 2009-01-15
Category : Juvenile Nonfiction
ISBN : 9781435850101

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Bone Cancer by Heather Hasan Pdf

A discussion of bone cancer and treatments for it.

Author : Tamra B. Orr
Publisher : The Rosen Publishing Group, Inc
Page : 74 pages
File Size : 45,5 Mb
Release : 2007-08-15
Category : Juvenile Nonfiction
ISBN : 140421934X

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Frequently Asked Questions About Bone Cancer by Tamra B. Orr Pdf

Describes how bone cancer is detected, diagnosed, and treated.

Author : Martin M. Malawer,Paul H. Sugarbaker
Publisher : Springer Science & Business Media
Page : 626 pages
File Size : 51,8 Mb
Release : 2007-05-08
Category : Medical
ISBN : 9780306484070

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Musculoskeletal Cancer Surgery by Martin M. Malawer,Paul H. Sugarbaker Pdf

Steven A. Rosenberg, MD In the past two decades significant progress has quality of life. The use of local radiation therapy has occurred, in the management of patients with mus- had a profound impact on the ability to achieve local loskeletal cancers, that has improved both the survival control. Cooperation between surgeons and radiation and the quality of life of afflicted patients. Changes in therapists often results in the tailoring of surgical p- the management of these patients have mirrored cedures to maximize the combined application of these trends in the entire field of oncology. two effective treatment modalities. Although impact on The most significant change has been improvement overall survival has not been demonstrated due to the in the surgical techniques for the resection of musculo- addition of radiation therapy, important advances in skeletal cancers based on a detailed understanding of improving the quality of life of patients receiving this the anatomic features of each particular tumor site, as combined-modality treatment have been evident. well as an appreciation of the natural biology that affects A third change impacting on the survival of patients the local spread of these tumors. The current volume of with musculoskeletal cancers has been the aggressive Musculoskeletal Cancer Surgery: Treatment of Sarcomas and resection of metastatic deposits.

Author : Per-Ulf Tunn
Publisher : Springer Science & Business Media
Page : 372 pages
File Size : 44,5 Mb
Release : 2008-12-28
Category : Medical
ISBN : 9783540779605

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Treatment of Bone and Soft Tissue Sarcomas by Per-Ulf Tunn Pdf

Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.

Author : R. Coleman,R. D. Rubens
Publisher : Parthenon Publishing
Page : 83 pages
File Size : 51,9 Mb
Release : 1992-06
Category : Bone and bones
ISBN : 1850704414

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Metastatic Bone Disease by R. Coleman,R. D. Rubens Pdf

Author : Marion Woodman
Publisher : Penguin
Page : 276 pages
File Size : 45,5 Mb
Release : 2001-12-01
Category : Health & Fitness
ISBN : 0140196285

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Bone by Marion Woodman Pdf

On November 7, 1993, Marion Woodman was diagnosed with uterine cancer. Here, in journal form, is the story of her illness, her healing process, and her acceptance of life and death. Breathtakingly honest about the factors she feels contributed to her cancer, Woodman also explains how she drew upon every resource-physical and spiritual-available to her to come to terms with her illness. Dreams and imagery, self-reflection and body work, and both traditional and alternative medicine play distinctive roles in Woodman's recovery. Her personal treasury of art, photographs, and quotations-from Dickinson to Blake to Rumi-embellish this unique chronicle of a very personal journey toward transformation.

Author : Dominique Heymann
Publisher : Academic Press
Page : 504 pages
File Size : 44,6 Mb
Release : 2009-08-20
Category : Medical
ISBN : 0080953883

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Bone Cancer by Dominique Heymann Pdf

The epidemiological and clinical importance of bone metastasis has long been recognized, but the past decade has seen an explosion in the fields of bone biology and bone cancer research. This period of time has been marked by a number of key discoveries that have led to the opening up of entirely new areas for investigation as well as new therapies which combine surgery and biological therapeutic approaches. Bone is a common site of cancer metastases - cancer cells commonly develop in bone and spread to other organ systems through the bloodstream. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on a patient's quality of life and are a main cause of patient mortality. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for the medical and cancer research communities. This book provides, all in one resource, the most recent data on bone cancer development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases. Feature Presents a comprehensive, translational source for all aspects of bone cancer in one reference work Bone cancer experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches. Clear presentation by bone biologists of the cellular and molecular mechanisms underlying bone tumors and bone cancer metastasis as well as the genomic and proteomic assays used in detecting cancer within given organ systems Clear presentation by oncologists and radiologists of how histopathology, imaging, and pain monitoring can lead to new therapeutic approaches Benefit Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of bone cancer issues, as opposed to searching through thousands of journal articles. Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system Correct diagnosis (and therefore correct treatment) of cancer depends on a strong understanding of the molecular basis for the disease – both oncologists and radiologists will benefit Bone biologists will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic and proteomic assays

Author : Minati Bisoyi
Publisher : Unknown
Page : 198 pages
File Size : 45,6 Mb
Release : 2019-07-12
Category : Electronic
ISBN : 1080127348

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Bone Cancer by Minati Bisoyi Pdf

Bone cancer is a harmful tumor of the bone that crushes ordinary bone cells. Essential bone malignancy is uncommon. The dominant part of individuals who have cancer in their bones have an auxiliary bone tumor. This implies the disease in their bones create from the spread, otherwise called a metastasis, from another cancer which grew somewhere else in their body. Bone malignancy alludes to the cases in which the disease begins in the bone cells and does exclude tumors that have spread to the bones. Optional or metastatic bone tumor can be appropriately alluded to as a carcinoma in light of where it initially emerged. Essential bone diseases are called sarcomas. Bone tumor is most normal in kids and young people. It is less basic in more established grown-ups. There are a few unique kinds of bone malignancy, and they can happen in any of the bones. Kinds of Bone Cancer -Osteosarcoma is the most widely recognized sort of bone tumor. It is most normal in guys between 10-25 years old, however it can likewise happen in more seasoned grown-ups. The in all likelihood areas for creating osteosarcoma are in the long bones of the arms and legs close to the development locales of the knees and shoulders. This is regularly an extremely forceful tumor, and it can spread (metastasize) to the lungs. -Ewing's sarcoma is an exceptionally forceful bone tumor. It is more typical in more youthful youngsters between 4-15 years of age. It is more typical in young men and once in a while found in those more than 30 years old. It is most ordinarily found in the center parts of the long bones in the arms and legs. It can likewise spread to the lungs and other body tissues. -Chondrosarcoma is the second most basic bone cancer. Rather than the beforehand portrayed tumors, chondrosarcoma creates from the ligament cells, not from the bone cells themselves. The pelvis and the hip and shoulder bones are most normally influenced. It is most basic in individuals more than 40 years old. It can likewise spread to the lungs and lymphatic framework. -Malignant stringy histiocytoma (MFH) is an uncommon kind of tumor which more regularly emerges from delicate tissues than from bone. When it emerges in bone, it is dealt with as if it was an osteosarcoma. It is most basic in individuals 50-60 years of age. It is most regular in the arms and legs, and is more typical in guys. -Fibrosarcoma is an uncommon delicate tissue tumor that most normally happens around the knee. It for the most part influences individuals 35-55 years of age and is more typical in guys. -Chordoma is an extremely uncommon tumor ordinarily found in individuals more than 30 years of age. It is most regularly found in either the lower or upper closures of the spinal segment.