Caenorhabditis Elegans

Author : Donald L. Riddle
Publisher : Firefly Books
Page : 1252 pages
File Size : 45,7 Mb
Release : 1997
Category : Medical
ISBN : 0879695323

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C. Elegans II by Donald L. Riddle Pdf

Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR

Author : William Barry Wood
Publisher : Unknown
Page : 694 pages
File Size : 40,6 Mb
Release : 1988
Category : Science
ISBN : UOM:39015049386132

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The Nematode Caenorhabditis Elegans by William Barry Wood Pdf

Author : Jerry J. Buccafusco
Publisher : CRC Press
Page : 341 pages
File Size : 51,7 Mb
Release : 2000-08-29
Category : Medical
ISBN : 9781420041811

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Methods of Behavior Analysis in Neuroscience by Jerry J. Buccafusco Pdf

Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 50,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Kevin Strange
Publisher : Springer Science & Business Media
Page : 292 pages
File Size : 48,8 Mb
Release : 2008-02-05
Category : Medical
ISBN : 9781597451512

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C. elegans by Kevin Strange Pdf

Molecular biology has driven a powerful reductionist, or “molecule-c- tric,” approach to biological research in the last half of the 20th century. Red- tionism is the attempt to explain complex phenomena by defining the functional properties of the individual components of the system. Bloom (1) has referred to the post-genome sequencing era as the end of “naïve reductionism. ” Red- tionist methods will continue to be an essential element of all biological research efforts, but “naïve reductionism,” the belief that reductionism alone can lead to a complete understanding of living organisms, is not tenable. Organisms are clearly much more than the sum of their parts, and the behavior of complex physiological processes cannot be understood simply by knowing how the parts work in isolation. Systems biology has emerged in the wake of genome sequencing as the s- cessor to reductionism (2–5). The “systems” of systems biology are defined over a wide span of complexity ranging from two macromolecules that interact to carry out a specific task to whole organisms. Systems biology is integrative and seeks to understand and predict the behavior or “emergent” properties of complex, multicomponent biological processes. A systems-level characteri- tion of a biological process addresses the following three main questions: (1) What are the parts of the system (i. e.

Author : Anna Menini
Publisher : CRC Press
Page : 448 pages
File Size : 46,5 Mb
Release : 2009-11-24
Category : Science
ISBN : 1420071998

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The Neurobiology of Olfaction by Anna Menini Pdf

Comprehensive Overview of Advances in Olfaction The common belief is that human smell perception is much reduced compared with other mammals, so that whatever abilities are uncovered and investigated in animal research would have little significance for humans. However, new evidence from a variety of sources indicates this traditional view is likely overly simplistic. The Neurobiology of Olfaction provides a thorough analysis of the state-of-the-science in olfactory knowledge and research, reflecting the growing interest in the field. Authors from some of the most respected laboratories in the world explore various aspects of olfaction, including genetics, behavior, olfactory systems, odorant receptors, odor coding, and cortical activity. Until recently, almost all animal research in olfaction was carried out on orthonasal olfaction (inhalation). It is only in recent years, especially in human flavor research, that evidence has begun to be obtained regarding the importance of retronasal olfaction (exhalation). These studies are beginning to demonstrate that retronasal smell plays a large role to play in human behavior. Highlighting common principles among various species – including humans, insects, Xenopus laevis (African frog), and Caenorhabditis elegans (nematodes) – this highly interdisciplinary book contains chapters about the most recent discoveries in odor coding from the olfactory epithelium to cortical centers. It also covers neurogenesis in the olfactory epithelium and olfactory bulb. Each subject-specific chapter is written by a top researcher in the field and provides an extensive list of reviews and original articles for students and scientists interested in further readings.

Author : Tim Schedl
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 49,8 Mb
Release : 2012-08-09
Category : Medical
ISBN : 9781461440154

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Germ Cell Development in C. elegans by Tim Schedl Pdf

Germ cells in sexually reproducing metazoa, through the germline lineage, are the route by which genetic material and cytoplasmic constituents are passed from one generation to the next in the continuum of life. Chapters in this book review germ cell development in the model organism Caenorhabditis elegans, discussing the biology, the genetics and the molecular mechanisms for various processes, as well as drawing comparisons with other organisms. Processes discussed include specification of germ cell fate, meiosis, gametogenesis, environmental/ physiological controls, epigenetics and translational control, fertilization and the oocyte-to-embryo transition. This book thus provides a comprehensive picture of the germline lineage and the continuum of life for the worm.

Author : David Biron,Gal Haspel
Publisher : Humana
Page : 0 pages
File Size : 50,7 Mb
Release : 2015-10-02
Category : Medical
ISBN : 1493928414

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C. elegans by David Biron,Gal Haspel Pdf

The aim of this volume is to provide a step-by-step guide for implementing a selection of novel techniques in the lab. Each protocol in this volume is presented as a standalone chapter, specifically geared towards addressing practical needs without presuming prior knowledge of the technique at hand. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, C. elegans: Methods and Applications, Second Edition aims to ensure successful results in the further study of this dynamic field.

Author : W.P. de Voogt
Publisher : Springer
Page : 196 pages
File Size : 49,7 Mb
Release : 2015-11-27
Category : Science
ISBN : 9783319235738

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Reviews of Environmental Contamination and Toxicology Volume 237 by W.P. de Voogt Pdf

Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

Author : Itamar Glazer,David I. Shapiro-Ilan,Paul W. Sternberg
Publisher : Cab International
Page : 0 pages
File Size : 54,6 Mb
Release : 2022
Category : Biological models
ISBN : 1789248817

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Nematodes as Model Organisms by Itamar Glazer,David I. Shapiro-Ilan,Paul W. Sternberg Pdf

"Nematodes, especially Caenorhabditis elegans have been used as a model for research in molecular biology since the 1960's. This is a much-needed update on research on fundamental processes in areas such as genetics, developmental biology, nutrition, toxicology, ecology, pharmacology and medicine"--

Author : Ian A. Hope
Publisher : OUP Oxford
Page : 306 pages
File Size : 47,6 Mb
Release : 1999-12-09
Category : Science
ISBN : 9780191591983

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C. elegans by Ian A. Hope Pdf

Caenorhabditis Elegans has been a popular model organism for biological research for over thirty years and has been used to investigate many aspects of animal development, for example apoptosis, the Hox genes, signal transduction pathways, and the development of the nervous system. It has recently taken on new importance with the publication of the entire genome sequence in 1998. The first chapter gives all the basic information on C. elegans required to use it: it's natural history, anatomy, life cycle, development, and evolution. Information on how to obtain, grow, and maintain C. elegans for use as a model system is given in Chapter 4. Chapters 2 and 3 describe the genome project and show how to use genome sequence information by searching the database for homologues using different search methods and then how to analyse the search data. The next chapter gives the essential practical details of transformation and common uses for the technique. Chapter 6 covers reverse genetics and describes strategies for gene inactivation that are known to work in C elegans: epigenetic inactivation and mutational germ line inactivation. Chapter 7 is designed to help the user analyse phenotype by microscopy and includes Normaski, fluorescence, 4-dimensional, and electron microscopy. Techniques for studying the neurobiology of C. elegans are given in chapter 8. Chapter 9 describes the three commonly used approaches for studying gene expression and Chapter 10 deals with the common methods of molecular biology essential for gene characterization. C. elegans is not the ideal organism for biochemical studies, but chapter 11 describes several procedures for producing biochemically useful quantities of pure tissues. The final chapter is about conventional genetics and details the standard procedures for selfing and crossing; mutagenesis and mutant screening; characterization of mutants; gene mapping; temperature-shift experiments and mosaic analysis. Caenorhabditis Elegans: A Practical Approach will therefore provide all the background information necessary for use of C. elegans as a model system.

Author : Kenneth Söderhäll
Publisher : Springer Science & Business Media
Page : 338 pages
File Size : 55,6 Mb
Release : 2011-06-28
Category : Medical
ISBN : 9781441980595

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Invertebrate Immunity by Kenneth Söderhäll Pdf

It can be seen that the insects are the still attracting most research and researchers. However, an increasing interest is emerging to study new invertebrate groups, especially those where the genome is known. Even though Drosophila has been and still is an excellent model for immune studies, it is now clear that there are great differences between immune responses in Drosophila and that of several other invertebrates, which indeed calls for more research on other invertebrates

Author : Henry F. Epstein,Diane C. Shakes
Publisher : Academic Press
Page : 687 pages
File Size : 42,8 Mb
Release : 1995
Category : Caenorhabditis elegans
ISBN : 9780125641494

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Caenorhabditis Elegans by Henry F. Epstein,Diane C. Shakes Pdf

The first of its kind, this laboratory handbook emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. Four primary sections--Genetic and Culture Methods, Neurobiology, Cell and Molecular Biology, and Genomics and Informatics--reflect the cross-disciplinary nature of C. elegans research. Because C. elegans is a simple and malleable organism with a small genome and few cell types, it provides an elegant demonstr.

Author : V.E.A. Russo,D.J. Cove,L.G. Edgar,R. Jaenisch,F. Salamini
Publisher : Springer Science & Business Media
Page : 551 pages
File Size : 51,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642598289

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Development by V.E.A. Russo,D.J. Cove,L.G. Edgar,R. Jaenisch,F. Salamini Pdf

Studies of organisms have led to a greatly improved understanding of the genetic mechanisms underlying developmental processes, and the epigenetic and environmental influences on these processes. This second edition reviews these three levels and their relative importance to give the reader a clear picture of one of the most exciting areas of current biological research.

Author : Hitoshi Sawada,Naokazu Inoue,Megumi Iwano
Publisher : Springer
Page : 463 pages
File Size : 49,7 Mb
Release : 2014-02-07
Category : Science
ISBN : 9784431545897

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Sexual Reproduction in Animals and Plants by Hitoshi Sawada,Naokazu Inoue,Megumi Iwano Pdf

This book contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews recent progress in almost all fields of plant and animal fertilization. It was recently reported that the self-sterile mechanism of a hermaphroditic marine invertebrate (ascidian) is very similar to the self-incompatibility system in flowering plants. It was also found that a male factor expressed in the sperm cells of flowering plants is involved in gamete fusion not only of plants but also of animals and parasites. These discoveries have led to the consideration that the core mechanisms or factors involved in sexual reproduction may be shared by animals, plants and unicellular organisms. This valuable book is highly useful for reproductive biologists as well as for biological scientists outside this field in understanding the current progress of reproductive biology.