Cancer Associated Viruses

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Viruses and Human Cancer

Mei Hwei Chang,Kuan-Teh Jeang
Viruses and Human Cancer Book PDF

Author : Mei Hwei Chang,Kuan-Teh Jeang
Publisher : Springer Science & Business Media
Page : 293 pages
File Size : 46,5 Mb
Release : 2013-09-06
Category : Medical
ISBN : 9783642389658

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Viruses and Human Cancer by Mei Hwei Chang,Kuan-Teh Jeang Pdf

Research on oncogenic viruses and related human cancers has advanced rapidly in the past decade. Most articles, however, focus on a specific oncogenic virus and cancer. There is consequently a need for a comprehensive, up-to-date monograph that offers broad and integrated knowledge. Viruses and Human Cancer – From Basic Science to Clinical Prevention is designed to meet this need by providing an advanced overview on the basic and clinical aspects of oncogenic viruses and the human cancers that they cause. Virology, virus-induced inflammation and tissue injuries, oncogenic mechanisms, epidemiology, and current and emerging preventive and therapeutic strategies are all discussed in detail. In addition, the book covers the individual aspects of seven oncogenic viruses, i.e., hepatitis B virus, hepatitis C virus, human papilloma virus, Epstein-Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes virus, and Merkel cell polyomavirus, and the related human cancers.

Cancer Associated Viruses

Erle S. Robertson
Cancer Associated Viruses Book PDF

Author : Erle S. Robertson
Publisher : Springer Science & Business Media
Page : 869 pages
File Size : 54,5 Mb
Release : 2012-02-14
Category : Medical
ISBN : 9781461400165

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Cancer Associated Viruses by Erle S. Robertson Pdf

The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.

Cancer-Causing Viruses and Their Inhibitors

Satya Prakash Gupta
Cancer Causing Viruses and Their Inhibitors Book PDF

Author : Satya Prakash Gupta
Publisher : CRC Press
Page : 516 pages
File Size : 43,8 Mb
Release : 2014-05-16
Category : Medical
ISBN : 9780429586064

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Cancer-Causing Viruses and Their Inhibitors by Satya Prakash Gupta Pdf

Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who di

Cancer Associated Viruses

Erle S. Robertson
Cancer Associated Viruses Book PDF

Author : Erle S. Robertson
Publisher : Springer
Page : 866 pages
File Size : 52,8 Mb
Release : 2012-02-14
Category : Medical
ISBN : 1461400171

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Cancer Associated Viruses by Erle S. Robertson Pdf

The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.

HIV/AIDS-Associated Viral Oncogenesis

Craig Meyers
HIV AIDS Associated Viral Oncogenesis Book PDF

Author : Craig Meyers
Publisher : Springer
Page : 250 pages
File Size : 41,9 Mb
Release : 2018-12-06
Category : Medical
ISBN : 9783030035020

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HIV/AIDS-Associated Viral Oncogenesis by Craig Meyers Pdf

One of the most important aspects of AIDS is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. This book specifically addresses viral-induced human cancers associated with AIDS and observed in the AIDS population. It addresses the specific treatment required in this special population and the molecular biology of the causative viral agents.

Viruses, Evolution and Cancer Basic Considerations

Edouard Kurstak
Viruses Evolution and Cancer Basic Considerations Book PDF

Author : Edouard Kurstak
Publisher : Elsevier
Page : 847 pages
File Size : 55,6 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323142298

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Viruses, Evolution and Cancer Basic Considerations by Edouard Kurstak Pdf

Viruses, Evolution and Cancer: Basic Considerations focuses on comparative biology and evolutionary aspects of DNA and RNA oncogenic viruses. Organized into seven parts, this book begins with a discussion on the host-cell-virus relationships. Some chapters follow that discuss the comparative aspects of DNA and RNA oncogenic viruses. This work also elucidates the effects of oncogenic viruses on cell surface metabolism. Other chapters explore the comparative viral oncology, comparative immunology of oncogenic viruses, and evolution of viruses. This book will be an invaluable material both to those concerned in the scientific and medical problems of cancer and will benefit all who are interested in virology and oncology.

Human Herpesviruses

Ann Arvin,Gabriella Campadelli-Fiume,Edward Mocarski,Patrick S. Moore,Bernard Roizman,Richard Whitley,Koichi Yamanishi
Human Herpesviruses Book PDF

Author : Ann Arvin,Gabriella Campadelli-Fiume,Edward Mocarski,Patrick S. Moore,Bernard Roizman,Richard Whitley,Koichi Yamanishi
Publisher : Cambridge University Press
Page : 1325 pages
File Size : 45,7 Mb
Release : 2007-08-16
Category : Medical
ISBN : 9781139461641

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Human Herpesviruses by Ann Arvin,Gabriella Campadelli-Fiume,Edward Mocarski,Patrick S. Moore,Bernard Roizman,Richard Whitley,Koichi Yamanishi Pdf

This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Cancer Virus

Dorothy H. Crawford,Alan Rickinson,Ingólfur Johannessen
Cancer Virus Book PDF

Author : Dorothy H. Crawford,Alan Rickinson,Ingólfur Johannessen
Publisher : Oxford University Press
Page : 219 pages
File Size : 46,8 Mb
Release : 2014-02
Category : Health & Fitness
ISBN : 9780199653119

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Cancer Virus by Dorothy H. Crawford,Alan Rickinson,Ingólfur Johannessen Pdf

Relates the story of the discovery of the Epstein-Barr virus in 1964 and how scientists are gradually coming to understand it, and considers why the virus causes apparently unrelated diseases in different populations.

Mechanisms of DNA Tumor Virus Transformation

Leonard J. Rosenthal
Mechanisms of DNA Tumor Virus Transformation Book PDF

Author : Leonard J. Rosenthal
Publisher : Karger Medical and Scientific Publishers
Page : 171 pages
File Size : 50,9 Mb
Release : 2001-01-01
Category : Medical
ISBN : 9783805572477

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Mechanisms of DNA Tumor Virus Transformation by Leonard J. Rosenthal Pdf

Approximately 15% of human cancer incidence can be attributed to virus infection, i.e. viruses represent the second most important risk factor (after tobacco consumption) for cancer development in humans. Today, five virus types are known to be involved in causing human cancer: papillomaviruses, retroviruses, herpesviruses, hepadnaviruses, and flaviviruses. This volume provides a comprehensive review of a number of DNA tumor viruses. Leading experts in the field of tumor virology discuss up-to-date information, focusing on the transforming genes of DNA tumor viruses, the mechanisms of transformation and the in vitro methodology used for their identification and characterization. In vitro studies have revealed several common mechanisms of viral transformation. Presented in a clear and concise manner, this book will be of value to students as well as researchers in the fields of general biology, molecular biology, cell biology and microbiology.

A Contagious Cause

Robin Wolfe Scheffler
A Contagious Cause Book PDF

Author : Robin Wolfe Scheffler
Publisher : University of Chicago Press
Page : 391 pages
File Size : 44,9 Mb
Release : 2019-06-15
Category : Medical
ISBN : 9780226628370

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A Contagious Cause by Robin Wolfe Scheffler Pdf

Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer “germ,” inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. ​ A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.

The Epstein-Barr Virus

M. A. Epstein,B. G. Achong
The Epstein Barr Virus Book PDF

Author : M. A. Epstein,B. G. Achong
Publisher : Springer Science & Business Media
Page : 467 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642672361

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The Epstein-Barr Virus by M. A. Epstein,B. G. Achong Pdf

The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.

Cancer Gene Therapy

David T. Curiel,Joanne T. Douglas
Cancer Gene Therapy Book PDF

Author : David T. Curiel,Joanne T. Douglas
Publisher : Springer Science & Business Media
Page : 490 pages
File Size : 52,6 Mb
Release : 2007-11-03
Category : Medical
ISBN : 9781592597857

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Cancer Gene Therapy by David T. Curiel,Joanne T. Douglas Pdf

A complete introduction and guide to the latest developments in cancer gene therapy-from bench to bedside. The authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and the targeting of the nonmalignant stromal cells that support their growth. They also thoroughly examine the advantages and limitations of the different therapies and detail strategies to overcome obstacles to their clinical implementation. Topics of special interest include vector-targeting techniques, the lessons learned to date from clinical trials of cancer gene therapy, and the regulatory guidelines for future trials. Noninvasive techniques to monitor the extent of gene transfer and disease regression during the course of treatment are also discussed.

Viral Oncology

Kamel Khalili,Kuan-Teh Jeang
Viral Oncology Book PDF

Author : Kamel Khalili,Kuan-Teh Jeang
Publisher : John Wiley & Sons
Page : 510 pages
File Size : 42,6 Mb
Release : 2010-08-03
Category : Medical
ISBN : 9780470930564

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Viral Oncology by Kamel Khalili,Kuan-Teh Jeang Pdf

Clinical oncologists and researchers now have a comprehensive single source of current information on cancer viruses obtained from bench and bedside. This important refernce allows further development of translational approaches for the effective treatment of patients with virus-associated malignancies. The book contains 25 chapters covering basic and clinical aspects of viruses, including HPV, HBV, HCV, polyomaviruses, Kaposi’s associated viruses, retroviruses (including HIV-1 associated malignancies), and EBV. Several chapters are devoted to basic science of oncogenic viruses for the study of their pathogenesis, drug development, and employment of viral vectors for vaccine and gene therapy. Clinical materials are embedded within chapters, and there are also complementary, clinically based chapters describing natural courses and treatments.

Holland-Frei Cancer Medicine

Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Holland Frei Cancer Medicine Book PDF

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 40,6 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

DNA Tumor Viruses

Giuseppe Barbanti-Brodano,Mauro Bendinelli,Herman Friedman
DNA Tumor Viruses Book PDF

Author : Giuseppe Barbanti-Brodano,Mauro Bendinelli,Herman Friedman
Publisher : Springer Science & Business Media
Page : 440 pages
File Size : 55,8 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781489911001

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DNA Tumor Viruses by Giuseppe Barbanti-Brodano,Mauro Bendinelli,Herman Friedman Pdf

DNA tumor viruses have long been useful experimental models of carcinogenesis and have elucidated several important mechanisms of cell transformation. Re search in recent years has shown that human tumors have a multifactorial nature and that some DNA tumor viruses may playa key role in their etiology. The aim of this book is to assess our knowledge of DNA tumor viruses by reviewing animal models, mechanisms of transformation, association with human tumors, and possi bilities of prevention and control by vaccination. Animal models of tumor virology have contributed significantly to our under standing of the epidemiology and pathogenesis of virus-induced tumors. Bovine papillomaviruses induce papillomas in the intestine of cattle. The papillomas undergo a transition to carcinomas in cows feeding on bracken fern, which pro duces a toxin with radiomimetic and immunosuppressive functions. This example of cooperation between a virus and chemical carcinogens parallels the cooperative role of human papillomaviruses (HPVs) and herpes simplex virus type 2 (HSV-2) with environmental carcinogens in the pathogenesis of cervical cancer. Likewise, hepatocarcinomas appearing in woodchucks chronically infected by woodchuck hepatitis virus (WIN) provide strong support for the relationship between hepatitis B virus (HBV) infection and human hepatocellular carcinoma. Also, the fact that WIN DNA integrates closely to cellular oncogenes suggests a possible molecular mechanism for the tumorigenesis induced by HBV.