Cancer Drug Design And Discovery

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Cancer Drug Discovery

Kyu-Won Kim,Jae Kyung Roh,Hee-Jun Wee,Chan Kim
Cancer Drug Discovery Book PDF

Author : Kyu-Won Kim,Jae Kyung Roh,Hee-Jun Wee,Chan Kim
Publisher : Springer
Page : 276 pages
File Size : 54,7 Mb
Release : 2016-11-14
Category : Medical
ISBN : 9789402408447

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Cancer Drug Discovery by Kyu-Won Kim,Jae Kyung Roh,Hee-Jun Wee,Chan Kim Pdf

The reader will discover a comprehensive and multifaceted overview of the history of the development of anticancer drugs deeply influenced by the cell concept of cancer and future directions for the development of new anticancer drugs. First, this book documents the scientific progress in biological science over the last 70 years and the influence this progress had in cancer research. Summaries and charts of important discoveries complete this overview. Furthermore, this book outlines the process of anticancer drug development with a focus on the characteristic drug groups of each era, related to advancements of chemistry and biological sciences. This book also provides brief mechanism of action of drugs, illustrated by comprehensive timelines and conceptual cartoons. This book finally sums up the limitations of the current anticancer drug development and seeks new directions for anticancer drug discovery, considering under the systemic view of cancer.

Cancer Drug Design and Discovery

Stephen Neidle
Cancer Drug Design and Discovery Book PDF

Author : Stephen Neidle
Publisher : Elsevier
Page : 496 pages
File Size : 46,8 Mb
Release : 2011-04-28
Category : Medical
ISBN : 0080554954

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Cancer Drug Design and Discovery by Stephen Neidle Pdf

The ultimate source of information on the design of new anticancer agents, emphasizing small molecules, this newest work covers recent notable successes resulting from the human genome and cancer genomics projects. These advances have provided information on targets involved in specific cancers that are leading to effective medicines for at least some of the common solid tumors. Unique sections explain the basic underlying principles of cancer drug development and provide a practical introduction to modern methods of drug design. Appealing to a broad audience, this is an excellent reference for translational researchers interested in cancer biology and medicine as well as students in pharmacy, pharmacology, or medicinal and biological chemistry and clinicians taking oncology options. * Covers both currently available drugs as well as those under development * Provides a clinical perspective on trials of new anticancer agents * Presents drug discovery examples through the use of case histories

Cancer Drug Design and Discovery

Stephen Neidle
Cancer Drug Design and Discovery Book PDF

Author : Stephen Neidle
Publisher : Academic Press
Page : 640 pages
File Size : 55,7 Mb
Release : 2013-09-30
Category : Medical
ISBN : 9780123972286

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Cancer Drug Design and Discovery by Stephen Neidle Pdf

Cancer Drug Design and Discovery, Second Edition is an important reference on the underlying principles for the design and subsequent development of new anticancer small molecule agents. New chapters have been added to this edition on areas of particular interest and therapeutic promise, including cancer genomics and personalized medicine, DNA-targeted agents and more. This book includes several sections on the basic and applied science of cancer drug discovery and features those drugs that are now approved for human use and are in the marketplace, as well as those that are still under development. By highlighting some of the general principles involved in taking molecules through basic science to clinical development, this book offers a complete and authoritative reference on the design and discovery of anticancer drugs for translational scientists and clinicians involved in cancer research. Provides a clinical perspective on the development of new molecularly targeted anticancer agents with the latest and most promising chemotherapeutic approaches Offers a broad view of where the field is going, what tools drug discovery is using to produce new agents and how they are evaluated in the laboratory and clinic Features 6 new chapters devoted to advances in technology and successful anticancer therapies, such as cancer genomics and personalized medicine, DNA-targeted agents, B-Raf inhibitors and more Each chapter includes extensive references to the primary and review literature, as well as to relevant web-based sources

Frontiers in Anti-Cancer Drug Discovery

Atta-ur-Rahman,M. Iqbal Choudhary
Frontiers in Anti Cancer Drug Discovery Book PDF

Author : Atta-ur-Rahman,M. Iqbal Choudhary
Publisher : Bentham Science Publishers
Page : 280 pages
File Size : 50,7 Mb
Release : 2015-05-05
Category : Medical
ISBN : 9781681080581

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Frontiers in Anti-Cancer Drug Discovery by Atta-ur-Rahman,M. Iqbal Choudhary Pdf

“Frontiers in Anti-Cancer Drug Discovery” is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The Ebook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field. The fifth volume of the series features chapters on the following topics: -Nutraceuticals and natural food products for cancer treatment -Pharmacogenomics in Anti-cancer treatment -Cancer stem cells -Potassium channel targeting for brain tumor treatment -Sorafenib in the management of hepatocellular carcinoma …and more.

Frontiers in Anti-Cancer Drug Discovery Volume 10

Atta-ur-Rahman ,M. Iqbal Choudhary
Frontiers in Anti Cancer Drug Discovery Volume 10 Book PDF

Author : Atta-ur-Rahman ,M. Iqbal Choudhary
Publisher : Bentham Science Publishers
Page : 252 pages
File Size : 54,9 Mb
Release : 2019-05-31
Category : Medical
ISBN : 9789811401916

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Frontiers in Anti-Cancer Drug Discovery Volume 10 by Atta-ur-Rahman ,M. Iqbal Choudhary Pdf

Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest advances in anti-cancer drug design and discovery. In each volume, eminent scientists contribute reviews relevant to all areas of rational drug design and drug discovery including medicinal chemistry,in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field. The tenth volume of the series features chapters covering the following topics: - Challenges in the Management of Hepatoblastoma - The Emerging Role of Monocarboxylate Transporter-1 in Cancer - In-vitro Anti-Proliferative Assays and Techniques Used in Pre-Clinical Anti-Cancer Drug Discovery - Recent Advances in the Development of Mesoporous Anti-Cancer Drug Nanocarriers - Polyphenols and Cancer - Glioblastoma Multiforme - Cutting Edge Targeting Strategies Utilizing Nanotechnology in Breast Cancer Therapy.

Frontiers in Anti-Cancer Drug Discovery

M. Iqbal Choudhary
Frontiers in Anti Cancer Drug Discovery Book PDF

Author : M. Iqbal Choudhary
Publisher : Unknown
Page : 128 pages
File Size : 52,6 Mb
Release : 2013-11-29
Category : Medical
ISBN : 1608058093

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Frontiers in Anti-Cancer Drug Discovery by M. Iqbal Choudhary Pdf

"Frontiers in Anti-Cancer Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug di

Anticancer Drug Development Guide

Beverly A. Teicher
Anticancer Drug Development Guide Book PDF

Author : Beverly A. Teicher
Publisher : Springer Science & Business Media
Page : 315 pages
File Size : 52,8 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781461581529

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Anticancer Drug Development Guide by Beverly A. Teicher Pdf

Experienced cancer researchers from pharmaceutical companies, government laboratories, and academia comprehensively review and describe the arduous process of cancer drug discovery and approval. They focus on using preclinical in vivo and in vitro methods to identify molecules of interest, detailing the targets and criteria for success in each type of testing and defining the value of the information obtained from the various tests. They also define each stage of clinical testing, explain the criteria for success, and outline the requirements for FDA approval. A companion volume by the same editor (Cancer Therapeutics: Experimental and Clinical Agents) reviews existing anticancer drugs and potential anticancer therapies. These two volumes in the Cancer Drug Discovery and Development series reveal how and why molecules become anticancer drugs and thus offer a blueprint for the present and the future of the field.

Frontiers in Anti-Cancer Drug Discovery

Atta Ur Rahman
Frontiers in Anti Cancer Drug Discovery Book PDF

Author : Atta Ur Rahman
Publisher : Unknown
Page : 328 pages
File Size : 55,8 Mb
Release : 2018-02-06
Category : Medical
ISBN : 1608058859

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Frontiers in Anti-Cancer Drug Discovery by Atta Ur Rahman Pdf

Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery, including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The book series is essential reading for all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Frontiers in Anti-Cancer Drug Discovery

Atta-ur-Rahman,M. Iqbal Choudhary
Frontiers in Anti Cancer Drug Discovery Book PDF

Author : Atta-ur-Rahman,M. Iqbal Choudhary
Publisher : Bentham Science Publishers
Page : 264 pages
File Size : 49,8 Mb
Release : 2016-11-02
Category : Medical
ISBN : 9781681082516

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Frontiers in Anti-Cancer Drug Discovery by Atta-ur-Rahman,M. Iqbal Choudhary Pdf

Frontiers in Anti-Cancer Drug Discovery is an eBook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field. The seventh volume of the series features chapters covering the following topics: - Malignant pleural mesothelioma - Colorectal cancer therapy - Drugs for treating pancreatic cancer - Adjuvant endocrine therapy for early breast cancer - Cyclin E and its potential use for liver cancer prognosis and therapy

Frontiers in Anti-Cancer Drug Discovery: Volume 12

Atta ur-Rahman,M. Iqbal Choudhary
Frontiers in Anti Cancer Drug Discovery Volume 12 Book PDF

Author : Atta ur-Rahman,M. Iqbal Choudhary
Publisher : Bentham Science Publishers
Page : 217 pages
File Size : 40,7 Mb
Release : 2021-08-09
Category : Medical
ISBN : 9789811487361

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Frontiers in Anti-Cancer Drug Discovery: Volume 12 by Atta ur-Rahman,M. Iqbal Choudhary Pdf

Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest advances in anti-cancer drug design and discovery. In each volume, eminent scientists contribute reviews relevant to all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field. This volume of the series focuses on reviews of treatments derived from natural sources (cannabinoid-based medicines and turmeric), immunotherapy, biomarkers for glioblastoma and some new drug targets for anti-cancer treatment. The reviews included in this volume are: - Cannabinoid-Based Anticancer Strategies: - The Beneficial Effects of Turmeric and Its Active Constituent in Cancer Treatment - Immunotherapy Approaches Focusing on Cancer Stem Cells - Immunotherapy for the Treatment of Hepatocellular Carcinoma - Role of Biomarkers in Developing Therapies for Glioblastoma Multiforme - Poly (ADP-ribose) Polymerases as New Drug Targets in Cancer Treatment

Principles of Anticancer Drug Development

Elizabeth Garrett-Mayer,Manuel Hidalgo,S. Gail Eckhardt,Neil J. Clendeninn
Principles of Anticancer Drug Development Book PDF

Author : Elizabeth Garrett-Mayer,Manuel Hidalgo,S. Gail Eckhardt,Neil J. Clendeninn
Publisher : Springer Science & Business Media
Page : 674 pages
File Size : 51,8 Mb
Release : 2010-12-29
Category : Medical
ISBN : 9781441973580

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Principles of Anticancer Drug Development by Elizabeth Garrett-Mayer,Manuel Hidalgo,S. Gail Eckhardt,Neil J. Clendeninn Pdf

A practical guide to the design, conduction, analysis and reporting of clinical trials with anticancer drugs.

Frontiers in Drug Design & Discovery

Atta-ur-Rahman ,M. Iqbal Choudhary
Frontiers in Drug Design Discovery Book PDF

Author : Atta-ur-Rahman ,M. Iqbal Choudhary
Publisher : Bentham Science Publishers
Page : 314 pages
File Size : 47,9 Mb
Release : 2017-08-01
Category : Medical
ISBN : 9781681083551

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Frontiers in Drug Design & Discovery by Atta-ur-Rahman ,M. Iqbal Choudhary Pdf

Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists have contributed chapters focused on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. This book series should prove to be of interest to all pharmaceutical scientists who are involved in research in drug design and discovery and who wish to keep abreast of rapid and important developments in the field.

Textbook of Drug Design and Discovery, Third Edition

Tommy Liljefors,Povl Krogsgaard-Larsen,Ulf Madsen
Textbook of Drug Design and Discovery Third Edition Book PDF

Author : Tommy Liljefors,Povl Krogsgaard-Larsen,Ulf Madsen
Publisher : CRC Press
Page : 596 pages
File Size : 41,6 Mb
Release : 2002-07-25
Category : Medical
ISBN : 0415282888

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Textbook of Drug Design and Discovery, Third Edition by Tommy Liljefors,Povl Krogsgaard-Larsen,Ulf Madsen Pdf

Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.

Frontiers in Anti-Cancer Drug Discovery: Volume 11

Atta-ur-Rahman ,Muhammad Iqbal Choudhary
Frontiers in Anti Cancer Drug Discovery Volume 11 Book PDF

Author : Atta-ur-Rahman ,Muhammad Iqbal Choudhary
Publisher : Bentham Science Publishers
Page : 163 pages
File Size : 47,9 Mb
Release : 2020-09-01
Category : Medical
ISBN : 9789811422126

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Frontiers in Anti-Cancer Drug Discovery: Volume 11 by Atta-ur-Rahman ,Muhammad Iqbal Choudhary Pdf

Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest advances in anti-cancer drug design and discovery. In each volume, eminent scientists contribute reviews relevant to all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field. The eleventh volume of the series focuses on reviews on targeted therapies and drug delivery systems. This volume covers the following topics: - PI3K/Akt/mTOR Pathway in Acute Lymphoblastic Leukemia Targeted Therapies - Polymeric Nanomedicines in Treatment of Breast Cancer: Review of Contemporary Research - Treatment of Lung Cancer in the New Era - Oral Administration of Cancer Chemotherapeutics Exploiting Self-Nanoemulsifying Drug Delivery System: Recent Progress and Application - Targeting Approaches for the Diagnosis and Treatment of Cancer.

Frontiers in Anti-Cancer Drug Discovery

Atta-ur Rahman,M. Iqbal Choudhary
Frontiers in Anti Cancer Drug Discovery Book PDF

Author : Atta-ur Rahman,M. Iqbal Choudhary
Publisher : Bentham Science Publishers
Page : 181 pages
File Size : 45,8 Mb
Release : 2017-07-06
Category : Medical
ISBN : 9781681083896

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Frontiers in Anti-Cancer Drug Discovery by Atta-ur Rahman,M. Iqbal Choudhary Pdf

Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest and the most important advances in anti-cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. Each volume is devoted to the major advances in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field. The eighth volume of the series features chapters covering the following topics: - T cells in gastrointestinal cancers - The pharmacology of adjudin – a male contraceptive with anti-cancer properties - Manipulating the tumor microenvironment - Treatment of hepatocellular carcinoma - Gold-based compounds as potential anti-cancer drug candidates - Oral nanostructure drug delivery for anti-cancer treatment