Cannabis And The Developing Brain

Author : Miriam Melis,Olivier J Manzoni
Publisher : Academic Press
Page : 362 pages
File Size : 46,7 Mb
Release : 2022-08-18
Category : Psychology
ISBN : 9780128236413

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Cannabis and the Developing Brain by Miriam Melis,Olivier J Manzoni Pdf

Marijuana is the most commonly used psychotropic drug in the United States, after alcohol. With the legalization and decriminalization of cannabis, momentum continues to build and propelled by the reduction of stigma associated to its consumption, there is growing concern regarding the long-term impact on brain function and behavior. Cannabis and the Developing Brain aims to provide comprehensive research on the effects of cannabis during neurodevelopment stages (i.e., perinatal and adolescent ages). This book introduces readers to vivo neural circuits, molecular and cellular mechanisms affected by cannabis exposure during three different temporal windows of brain vulnerability. Second, it offers a unique insight to shared neurobiological features of cannabinoid exposure during different developmental periods. Lastly, Cannabis and the Developing Brain determines the adverse impact of developmental cannabinoid exposure on specific cognition, emotion and behaviors. Reviews exposure effects on different areas and circuits of the brain Identifies effects of exposure at prenatal, perinatal, infant, and adolescent ages Includes cannabis interaction with known genetic and environmental risk factors Contains neurodevelopment and neuropsychiatric disorders associated with cannabis exposure

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda
Publisher : National Academies Press
Page : 487 pages
File Size : 55,7 Mb
Release : 2017-03-31
Category : Science
ISBN : 9780309453073

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The Health Effects of Cannabis and Cannabinoids by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda Pdf

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Author : Timmen Cermak
Publisher : Cambridge University Press
Page : 257 pages
File Size : 41,8 Mb
Release : 2020-04-02
Category : Medical
ISBN : 9781108735735

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A Psychiatrist's View of Marijuana by Timmen Cermak Pdf

An essential guide covering the scientific knowledge and communication skills required to deliver objective patient advice about marijuana use.

Author : David Castle,Robin Murray
Publisher : Cambridge University Press
Page : 238 pages
File Size : 47,6 Mb
Release : 2004-05-27
Category : Medical
ISBN : 1139451650

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Marijuana and Madness by David Castle,Robin Murray Pdf

This book provides a comprehensive overview of the psychiatry and neuroscience of Cannabis sativa (marijuana), with particular emphasis on psychotic disorders. It outlines developments in our understanding of the human cannabinoid system, and links this knowledge to clinical and epidemiological facts about the impact of cannabis on mental health. Clinically focused chapters review not only the direct psychomimetic properties of cannabis, but also the impact consumption has on the courses of evolving or established mental illness such as schizophrenia. A number of controversial issues are critically explored, including whether a discrete 'cannabis psychosis' exists, and whether cannabis can actually cause schizophrenia. Effects of cannabis on mood, notably depression, are reviewed, as are its effects on cognition. This book will be of interest to all members of the mental health team, as well as to neuroscientists and those involved in drug and alcohol research.

Author : Institute of Medicine,Janet Joy,Alison Mack
Publisher : National Academies Press
Page : 216 pages
File Size : 53,7 Mb
Release : 2000-12-30
Category : Medical
ISBN : 9780309065313

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Marijuana As Medicine? by Institute of Medicine,Janet Joy,Alison Mack Pdf

Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.

Author : Don Cahalan,Ira H. Cisin,Helen M. Crossley
Publisher : Unknown
Page : 296 pages
File Size : 47,9 Mb
Release : 1969
Category : Social Science
ISBN : UOM:39015010658600

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American Drinking Practices by Don Cahalan,Ira H. Cisin,Helen M. Crossley Pdf

Author : Institute of Medicine
Publisher : National Academies Press
Page : 288 pages
File Size : 50,8 Mb
Release : 1999-07-10
Category : Medical
ISBN : 9780309071550

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Marijuana and Medicine by Institute of Medicine Pdf

The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€"the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers.

Author : British Medical Association
Publisher : CRC Press
Page : 164 pages
File Size : 45,7 Mb
Release : 1997-11-18
Category : Medical
ISBN : 9057023180

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Therapeutic Uses of Cannabis by British Medical Association Pdf

At the last Annual Representative Meeting of the British Medical Association a motion was passed that `certain additional cannabinoids should be legalized for wider medicinal use.'' This report supports this landmark statement by reviewing the scientific evidence for the therapeutic use of cannabinoids and sets the agenda for change. It will be welcomed by those who believe that cannabinoids can be used in medical treatment. The report discusses in a clear and readable form the use and adverse effects of the drug for nausea, multiple sclerosis, pain, epilepsy, glaucoma, and asthma.

Author : Roger Roffman,Robert S. Stephens
Publisher : Cambridge University Press
Page : 357 pages
File Size : 47,6 Mb
Release : 2006-02-23
Category : Medical
ISBN : 9781139449557

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Cannabis Dependence by Roger Roffman,Robert S. Stephens Pdf

Cannabis dependence is controversial. Does it occur or is it a myth put forth by those who oppose legalisation? What are the signs of cannabis dependence? How many people are affected? What are the health and behavioural risks of becoming cannabis-dependent? What counselling approaches have been tested with adults and adolescents, and how effective are they? What are the arguments for legalisation, regulation or prohibition? Looking back and toward the future, what do we know and what do we need to learn? This state-of-the-science review sets out to answer all those questions, beginning with an historical examination and moving into diagnosis, classification, epidemiology, public health, policy, issues relating to regulation and prohibition, and evidence-based interventions.

Author : Everhealth Publishing
Publisher : Zander Pearce
Page : 38 pages
File Size : 46,6 Mb
Release : 2023-11-28
Category : Self-Help
ISBN : 9798890082527

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Cannabis Influence On Adolescent And Young Adult Brain Function - Based On The Teachings Of Dr. Andrew Huberman by Everhealth Publishing Pdf

CANNABIS INFLUENCE ON ADOLESCENT AND YOUNG ADULT BRAIN FUNCTION - THE IMPACT OF MARIJUANA USE ON DEVELOPING MINDS BASED ON THE TEACHINGS OF DR. ANDREW HUBERMAN Are you ready to take charge of your health and transform your life? Are you curious about the benefits of "CANNABIS INFLUENCE ON ADOLESCENT AND YOUNG ADULT BRAIN FUNCTION" and how it can enhance your overall well-being? Wondering if it's the missing piece in your quest for a healthier life? Our book explores every aspect of "CANNABIS INFLUENCE ON ADOLESCENT AND YOUNG ADULT BRAIN FUNCTION" providing you with a comprehensive understanding of its potential to improve your health. Discover the secrets behind this remarkable supplement, and unlock its power to transform your life. BOOK CONTENT: Introduction to Cannabis Legalization Positive Effects vs. Negative Effects of Cannabis Distinction in Cannabis Use Ages Impact on Brain Development Reference to Lancet Psychiatry Study Findings from Lancet Psychiatry Study Concerns about Increasing THC Potency Call to Reduce Cannabis Use in Adolescents and Teens Prevalence of Cannabis Use in Young Adults Misconceptions about Cannabis The Risk of Young People Adopting Cannabis Use ABOUT THIS BOOK: This book is based on the teachings of Dr. Andrew Huberman. It has been expanded for better understanding. Everyone is dedicated to his scientific research, findings, and experimentation. It has been created to provide more people with access to his work and to help individuals lead healthier lives. ABOUT HIS TEACHINGS: Andrew Huberman, the renowned neuroscientist, delves into several recurring themes in his work. Central to his research is neural plasticity, the brain's remarkable ability to adapt and rewire itself. He explores how vision and respiration influence brain states, shedding light on fear, focus, and overall mental well-being. A strong advocate for the power of nutrition and lifestyle, Huberman emphasizes their impact on physiological metrics, stress mitigation, and improved sleep. ABOUT DR. ANDREW HUBERMAN: Dr. Andrew Huberman, born in 1976, is a distinguished neuroscientist. As a tenured professor at Stanford School of Medicine, he has made significant contributions to brain science and neural plasticity research. His renowned Huberman Lab podcast and work in vision science have made complex neuroscience accessible and garnered global recognition.

Author : Samer N. Narouze
Publisher : Springer Nature
Page : 339 pages
File Size : 55,6 Mb
Release : 2021-07-01
Category : Medical
ISBN : 9783030691868

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Cannabinoids and Pain by Samer N. Narouze Pdf

This book presents a well-balanced view of the potential medical use of cannabinoids in pain. It comprehensively covers the current challenges with medical cannabis utilization and provides recommendations for research and future directions. Organized into nine sections, the book begins with an introduction to medical cannabis, including its history, regulations, and the general attitudes of pain physicians on cannabis. Section two explores the biological effects of marijuana via the endocannabinoid system and its complex structure of receptors and enzymes. Sections three, four, and five then delve further into pharmacology and the mechanisms of action applicable to cannabinoids in managing pain. Timely and socially conscious, section six examines the benefits of substituting opioids with cannabinoids for preoperative management. Echoing the book's well-rounded content, sections seven and eight consider the challenges with medical cannabis, including safety and quality control, brain development risks, vaping hazards, and withdrawal. The book then closes with a look at the future of cannabis in medical research. Thoroughly and equitably composed, Cannabinoids and Pain is an invaluable resource for primary care physicians, pain and palliative care physicians, and oncologists.

Author : Frances E. Jensen,Amy Ellis Nutt
Publisher : Harper Collins
Page : 303 pages
File Size : 51,8 Mb
Release : 2015-01-06
Category : Psychology
ISBN : 9780062067869

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The Teenage Brain by Frances E. Jensen,Amy Ellis Nutt Pdf

A New York Times Bestseller Renowned neurologist Dr. Frances E. Jensen offers a revolutionary look at the brains of teenagers, dispelling myths and offering practical advice for teens, parents and teachers. Dr. Frances E. Jensen is chair of the department of neurology in the Perelman School of Medicine at the University of Pennsylvania. As a mother, teacher, researcher, clinician, and frequent lecturer to parents and teens, she is in a unique position to explain to readers the workings of the teen brain. In The Teenage Brain, Dr. Jensen brings to readers the astonishing findings that previously remained buried in academic journals. The root myth scientists believed for years was that the adolescent brain was essentially an adult one, only with fewer miles on it. Over the last decade, however, the scientific community has learned that the teen years encompass vitally important stages of brain development. Samples of some of the most recent findings include: Teens are better learners than adults because their brain cells more readily "build" memories. But this heightened adaptability can be hijacked by addiction, and the adolescent brain can become addicted more strongly and for a longer duration than the adult brain. Studies show that girls' brains are a full two years more mature than boys' brains in the mid-teens, possibly explaining differences seen in the classroom and in social behavior. Adolescents may not be as resilient to the effects of drugs as we thought. Recent experimental and human studies show that the occasional use of marijuana, for instance, can cause lingering memory problems even days after smoking, and that long-term use of pot impacts later adulthood IQ. Multi-tasking causes divided attention and has been shown to reduce learning ability in the teenage brain. Multi-tasking also has some addictive qualities, which may result in habitual short attention in teenagers. Emotionally stressful situations may impact the adolescent more than it would affect the adult: stress can have permanent effects on mental health and can to lead to higher risk of developing neuropsychiatric disorders such as depression. Dr. Jensen gathers what we’ve discovered about adolescent brain function, wiring, and capacity and explains the science in the contexts of everyday learning and multitasking, stress and memory, sleep, addiction, and decision-making. In this groundbreaking yet accessible book, these findings also yield practical suggestions that will help adults and teenagers negotiate the mysterious world of adolescent development.

Author : Judith Grisel
Publisher : Anchor
Page : 258 pages
File Size : 55,7 Mb
Release : 2020-01-14
Category : Psychology
ISBN : 9780525434900

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Never Enough by Judith Grisel Pdf

A NEW YORK TIMES BESTSELLER From a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction. Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice. With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities. Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.

Author : Emmanuel S Onaivi,Takayuki Sugiura,Vincenzo Di Marzo
Publisher : CRC Press
Page : 592 pages
File Size : 53,9 Mb
Release : 2005-11-01
Category : Science
ISBN : 1420023640

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Endocannabinoids by Emmanuel S Onaivi,Takayuki Sugiura,Vincenzo Di Marzo Pdf

Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana, and the finding of endogenous cannabinoids, which also activate the receptors, have transformed cannabinoid research into mainstream science with significant implications in human health and disease Endocannabinoids: The Brain and Body’s Marijuana and Beyond documentsadvances in the discovery and functioning of naturally occurring marijuana-like substances in human biology. It explores recent findings that point to the existence of an endocannabinoid physiological control system (EPCS) that directly impacts human development, health, and disease. While cannabinoid effects on the brain have received the greatest attention throughout the literature, this work looks at research on the endogenous cannabinoid system’s association across all of human physiology, including the immune, endocrine, and reproductive systems. With thoroughly researched and exceptionally insightful contributions from more than three-dozen top-flight researchers representing a cross-section of disciplines from molecular biology, genetics, and neurology to gynecology, physiology, and pharmacology, this work explores a range of topics as wide as the human body is complex. These topics include the EPCS’s relation to cell development and regulation, CNS function, immune function modulation, reproduction, and digestion, as well as its function in mental illness, neurodegenerative diseases, and cancer. The final section in the book considers the significance of endogenous cannabinoids found in some of the simplest multicellular organisms in the animal kingdom, as well as in mammalian cells at the earliest stages of development, all of which suggests that they play a fundamental role in human biology. Enocannabinoids: The Brain and Body’s Marijuana and Beyond explores areas that few books have ventured into, providing cutting-edge information that will ultimately help us better understand human biology at the systemic and perhaps even cellular level, as well as lead to the development of a whole new range of medications.

Author : Marco Colizzi,Sagnik Bhattacharyya
Publisher : MDPI
Page : 204 pages
File Size : 52,6 Mb
Release : 2021-02-05
Category : Science
ISBN : 9783039439959

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Cannabis by Marco Colizzi,Sagnik Bhattacharyya Pdf

Over the years, there has been increasing interest into the public health impact of cannabis use, especially by young adults. This follows the evidence of a growing prevalence of regular cannabis use worldwide, with approximately 200 million users. Recreational cannabis use, especially a frequent use of products with high levels of its main psychoactive ingredient delta-9-tetrahydrocannabinol (Δ 9-THC), can cause dependence and have transient and long-lasting detrimental mental health effects, also negatively impacting cognitive processing and brain function and metabolism. In regular users, the development of tolerance to some of the effects of cannabis, especially the pleasurable ones, may lead to progressively heavier use in order to obtain the same effects in terms of their intensity, with higher health risks. However, the Cannabis Sativa plant contains different chemicals with different potential effects. In this regard, cannabidiol has gained interest because of its potential therapeutic properties, in line with evidence that CBD and Δ9-THC may exhibit opposite effects at the cannabinoid receptor type 1 (CB1), Δ9-THC being a partial agonist and CBD an antagonist/inverse agonist. Different cannabinoids may modulate human brain function and behavior in different ways, with different risk–benefit profiles.