Carbohydrate Active Enzymes

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Carbohydrate-Active Enzymes

Stefano Benini
Carbohydrate Active Enzymes Book PDF

Author : Stefano Benini
Publisher : MDPI
Page : 408 pages
File Size : 50,6 Mb
Release : 2020-06-18
Category : Science
ISBN : 9783039360901

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Carbohydrate-Active Enzymes by Stefano Benini Pdf

Carbohydrate-active enzymes are responsible for both biosynthesis and the breakdown of carbohydrates and glycoconjugates. They are involved in many metabolic pathways; in the biosynthesis and degradation of various biomolecules, such as bacterial exopolysaccharides, starch, cellulose and lignin; and in the glycosylation of proteins and lipids. Carbohydrate-active enzymes are classified into glycoside hydrolases, glycosyltransferases, polysaccharide lyases, carbohydrate esterases, and enzymes with auxiliary activities (CAZy database, www.cazy.org). Glycosyltransferases synthesize a huge variety of complex carbohydrates with different degrees of polymerization, moieties and branching. On the other hand, complex carbohydrate breakdown is carried out by glycoside hydrolases, polysaccharide lyases and carbohydrate esterases. Their interesting reactions have attracted the attention of researchers across scientific fields, ranging from basic research to biotechnology. Interest in carbohydrate-active enzymes is due not only to their ability to build and degrade biopolymers—which is highly relevant in biotechnology—but also because they are involved in bacterial biofilm formation, and in glycosylation of proteins and lipids, with important health implications. This book gathers new research results and reviews to broaden our understanding of carbohydrate-active enzymes, their mutants and their reaction products at the molecular level.

Carbohydrate-Active Enzymes

K.-H. Park
Carbohydrate Active Enzymes Book PDF

Author : K.-H. Park
Publisher : Elsevier
Page : 312 pages
File Size : 55,8 Mb
Release : 2008-09-23
Category : Technology & Engineering
ISBN : 9781845695750

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Carbohydrate-Active Enzymes by K.-H. Park Pdf

Recent advances in biochemistry and biotechnology have enabled significant progress in basic research on carbohydrate-active enzymes and advances in their effective application. The mechanism of catalytic reaction of carbohydrate-active enzymes is not fully understood, though, as they often show unusual substrate specificity and modes of action. This comprehensive collection summarises some of the most important research in the field of carbohydrate-active enzymes, focusing on the enzymatic reaction mechanism, structure-function relationship and role in the living organism The book is based on papers presented in the 2008 Agricultural Biotechnology Symposium Carbohydrate-active enzymes: structure, function and applications held on September 26th-27th 2008 in Seoul National University, Korea. This symposium was organized by the Center for Agricultural Biomaterials, Seoul National University, Korea, which has organized symposia on agricultural biotechnology annually since 1990. Many important results on new types of carbohydrate-active enzymes and their applications have been reported at these meetings. Papers in Part one of this collection focus on structure-function relationships of carbohydrate-active enzymes. Papers in Part two discuss functions and applications of carbohydrate-active enzymes, such as enzymes for grain processing and glycosidases and their mutants as useful tools for glycoside synthesis. With its distinguished editor and international team of contributors, Carbohydrate-active enzymes: structure, function and applications is an essential reference for research scientists, post-graduate students and those in the food industry with an interest in enzymes. Summarises some of the most important research in the field of carbohydrate-active enzymes Covers topics ranging from enzyme classification and structural elucidation to applications of enzymes in food processing and other industries

Carbohydrate-Active Enzymes

Stefano Benini
Carbohydrate Active Enzymes Book PDF

Author : Stefano Benini
Publisher : Unknown
Page : 408 pages
File Size : 53,7 Mb
Release : 2020
Category : Electronic
ISBN : 3039360914

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Carbohydrate-Active Enzymes by Stefano Benini Pdf

Carbohydrate-active enzymes are responsible for both biosynthesis and the breakdown of carbohydrates and glycoconjugates. They are involved in many metabolic pathways; in the biosynthesis and degradation of various biomolecules, such as bacterial exopolysaccharides, starch, cellulose and lignin; and in the glycosylation of proteins and lipids. Carbohydrate-active enzymes are classified into glycoside hydrolases, glycosyltransferases, polysaccharide lyases, carbohydrate esterases, and enzymes with auxiliary activities (CAZy database, www.cazy.org). Glycosyltransferases synthesize a huge variety of complex carbohydrates with different degrees of polymerization, moieties and branching. On the other hand, complex carbohydrate breakdown is carried out by glycoside hydrolases, polysaccharide lyases and carbohydrate esterases. Their interesting reactions have attracted the attention of researchers across scientific fields, ranging from basic research to biotechnology. Interest in carbohydrate-active enzymes is due not only to their ability to build and degrade biopolymers--which is highly relevant in biotechnology--but also because they are involved in bacterial biofilm formation, and in glycosylation of proteins and lipids, with important health implications. This book gathers new research results and reviews to broaden our understanding of carbohydrate-active enzymes, their mutants and their reaction products at the molecular level.

Enzymatic Technologies for Marine Polysaccharides

Antonio Trincone
Enzymatic Technologies for Marine Polysaccharides Book PDF

Author : Antonio Trincone
Publisher : CRC Press
Page : 527 pages
File Size : 52,9 Mb
Release : 2019-04-08
Category : Medical
ISBN : 9780429608438

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Enzymatic Technologies for Marine Polysaccharides by Antonio Trincone Pdf

The bioactivity potential of marine polysaccharides has long been considered an underexploited aspect. These molecules found in seaweed, microalgae, bacteria, and animal fish (shellfish, mollusks, etc.) and the derived oligosaccharides need to be explored thoroughly with an interdisciplinary approach. They are an extraordinary source of chemical diversity, and the literature highlights many applicative fields, including the food industry, cosmetics, biomedicine, agriculture, environmental protection, wastewater management, etc. More recently, a new challenge has emerged: the exploitation of marine biomass as the source of sustainable energy to participate in the future replacement of fossil resources. Enzymatic Technologies for Marine Polysaccharides provides insight into the recent research developments of marine polysaccharides and their current and potential applications. The first section of the book explores the diversity of marine polysaccharides from various angles, including a description of the chemical complexity and current applications and new perspectives in food, pharmaceutical, cosmetics, and biomaterials offered by recent research. Efficient valorization of the marine polysaccharide biomass requires a rigorous analysis of the polysaccharides structure and their biological properties. The second section of the book concerns the development of extraction techniques and the improvement of the methods aimed at the characterization of their structure and function. Finally, the third and last section of the book articulates the enzymatic technologies from the discovery of novel enzymes to their production pipelines related to the fields of biorefinery, food, pharmaceutics, and other fine chemicals. Presents the latest research in marine oligosaccharides and polysaccharides Written by world-class researchers in marine enzyme technology Discusses the latest developments in extraction methods Presents a detailed overview of enzymatic routes for modification, production, and synthesis of marine oligosaccharides Contains extensive references at the end of each chapter to enhance further study

Carbohydrate Bioengineering

S.B. Petersen,B. Svensson,S. Pedersen
Carbohydrate Bioengineering Book PDF

Author : S.B. Petersen,B. Svensson,S. Pedersen
Publisher : Elsevier
Page : 385 pages
File Size : 47,7 Mb
Release : 1995-12-08
Category : Technology & Engineering
ISBN : 9780080528519

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Carbohydrate Bioengineering by S.B. Petersen,B. Svensson,S. Pedersen Pdf

The Carbohydrate Bioengineering Meeting held in Elsinore, Denmark, April 23-26, 1995, gathered 230 scientists, mostly from Europe, with interest in carbohydrate analysis and structure; carbohydrates in medicine and glycopathology; structure, function, application, and protein engineering of carbohydrate active enzymes; oligo- and polysaccharides of industrial interest; and production of carbohydrate containing new materials. The first chapters address glycoconjugates as modulatory and recognition molecules, structure determination using NMR and mass spectrometry, and microdialysis-chip enzyme-based sensors. Active site mutations coupled with crystal structures and synthetic substrate analogue interactions as well as new three-dimensional structures and binding domains for biotechnological applications are included in the chapters. Carbohydrate active enzymes turned out to be a predominant topic. The rapid development in glycobiology and glycotechnology has resulted in an enormous increase in our knowledge on the structure conversion, and application of carbohydrates in industry and medicine.

Chitin and Chitosan

Lambertus A. M. van den Broek,Carmen G. Boeriu
Chitin and Chitosan Book PDF

Author : Lambertus A. M. van den Broek,Carmen G. Boeriu
Publisher : John Wiley & Sons
Page : 534 pages
File Size : 42,6 Mb
Release : 2020-01-21
Category : Science
ISBN : 9781119450436

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Chitin and Chitosan by Lambertus A. M. van den Broek,Carmen G. Boeriu Pdf

Offers a comprehensive guide to the isolation, properties and applications of chitin and chitosan Chitin and Chitosan: Properties and Applications presents a comprehensive review of the isolation, properties and applications of chitin and chitosan. These promising biomaterials have the potential to be broadly applied and there is a growing market for these biopolymers in areas such as medical and pharmaceutical, packaging, agricultural, textile, cosmetics, nanoparticles and more. The authors – noted experts in the field – explore the isolation, characterization and the physical and chemical properties of chitin and chitosan. They also examine their properties such as hydrogels, immunomodulation and biotechnology, antimicrobial activity and chemical enzymatic modifications. The book offers an analysis of the myriad medical and pharmaceutical applications as well as a review of applications in other areas. In addition, the authors discuss regulations, markets and perspectives for the use of chitin and chitosan. This important book: Offers a thorough review of the isolation, properties and applications of chitin and chitosan. Contains information on the wide-ranging applications and growing market demand for chitin and chitosan Includes a discussion of current regulations and the outlook for the future Written for Researchers in academia and industry who are working in the fields of chitin and chitosan, Chitin and Chitosan: Properties and Applications offers a review of these promising biomaterials that have great potential due to their material properties and biological functionalities.

A Practical Guide to Using Glycomics Databases

Kiyoko F. Aoki-Kinoshita
A Practical Guide to Using Glycomics Databases Book PDF

Author : Kiyoko F. Aoki-Kinoshita
Publisher : Springer
Page : 0 pages
File Size : 46,8 Mb
Release : 2018-07-07
Category : Science
ISBN : 4431567909

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A Practical Guide to Using Glycomics Databases by Kiyoko F. Aoki-Kinoshita Pdf

This book provides glycoscientists with a handbook of useful databases that can be applied to glycoscience research. Although many databases are now publicly available, one of the hurdles for their users is the learning curve required to effectively utilize those databases. Therefore, this book not only describes the existing databases, but also provides tips on how to obtain the target data. That is, because many databases provide a variety of data that could be obtained from different perspectives, each chapter provides users with potential biological questions that can be answered by a particular database and step-by-step instructions, with figures, on how to obtain that data. Troubleshooting tips are also provided to aid users encountering problems that can be predicted when using these databases. Moreover, contact information for each database is provided in case unexpected issues arise.

Protein-Carbohydrate Interactions

D. Wade Abbott,Alicia Lammerts van Bueren
Protein Carbohydrate Interactions Book PDF

Author : D. Wade Abbott,Alicia Lammerts van Bueren
Publisher : Humana Press
Page : 311 pages
File Size : 43,8 Mb
Release : 2017-05-02
Category : Science
ISBN : 149396898X

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Protein-Carbohydrate Interactions by D. Wade Abbott,Alicia Lammerts van Bueren Pdf

This volume is a wide-ranging tool for studying protein-carbohydrate interactions that extend from traditional biochemical methods to state-of-the-art techniques. This book focuses on four different research themes: Part I describes methods for screening and quantifying CAZyme activity; Part II contains methods for investigating the interactions between proteins and carbohydrate ligands; Part III discusses methods for the visualization of carbohydrates and protein-carbohydrate complexes; and Part IV focuses on structural and “omic” approaches for studying systems of CAZymes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Protein-Carbohydrate Interactions: Methods and Protocols is a valuable resource to the glycomics research community. In this continuously advancing field, the methods in this book highlight the biology of glycomics, thus driving biotechnological innovation and solutions for human health and sustainable resources within the emerging green community.

Handbook of Industrial Biocatalysis

Ching T. Hou
Handbook of Industrial Biocatalysis Book PDF

Author : Ching T. Hou
Publisher : CRC Press
Page : 616 pages
File Size : 50,5 Mb
Release : 2005-06-09
Category : Science
ISBN : 9781420027969

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Handbook of Industrial Biocatalysis by Ching T. Hou Pdf

Until now, no comprehensive handbook on industrial biocatalysis has been available. Soliciting chapters on virtually every aspect of biocatalysis from international experts most actively researching the field, the Handbook of Industrial Biocatalysis fills this need. The handbook is divided into three sections based on types of substrates. T

Carbohydrate Bioengineering

Tuula T. Teeri
Carbohydrate Bioengineering Book PDF

Author : Tuula T. Teeri
Publisher : Royal Society of Chemistry
Page : 210 pages
File Size : 49,5 Mb
Release : 2002
Category : Medical
ISBN : 085404826X

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Carbohydrate Bioengineering by Tuula T. Teeri Pdf

Carbohydrate bioengineering is a rapidly expanding field with many applications in medicine and industry. Presenting state-of-the-art research, Carbohydrate Bioengineering: Interdisciplinary Approaches brings together international experts on many different aspects of this burgeoning topic. Coverage includes: the engineering of glycosidases for constructive purposes; structure-function studies and protein engineering of carbohydrate-active enzymes; chemo-enzymatic carbohydrate synthesis; and trends emerging from comprehensive work on genomes and glycomes. This timely publication will be welcomed by all those needing access to the latest research in the field, including practitioners in the medicinal, chemical, food and pharmaceutical areas.

Enzymes for Carbohydrate Engineering

K.-H. Park,J.F. Robyt,Y-D. Choi
Enzymes for Carbohydrate Engineering Book PDF

Author : K.-H. Park,J.F. Robyt,Y-D. Choi
Publisher : Elsevier
Page : 214 pages
File Size : 44,5 Mb
Release : 1996-08-06
Category : Science
ISBN : 0080544592

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Enzymes for Carbohydrate Engineering by K.-H. Park,J.F. Robyt,Y-D. Choi Pdf

This book describes the recent developments in enzymology in carbohydrate engineering based on modern sciences and technology, collected from recent symposia on agricultural biotechnology. It builds a bridge between basic knowledge and biotechnology in the field of carbohydrate chemistry and enzymology. The fundamental research and application of carbohydrate enzymes to agricultural biotechnology, concentrating on the structures and biochemical properties of various enzymes, and their production and application in plant and food is extensively described. This book will provide the reader with the most up-to-date information on development of enzymology in carbohydrate engineering.

Carbohydrate Bioengineering

Tuula T Teeri,B Svensson,H J Gilbert,T Feizi
Carbohydrate Bioengineering Book PDF

Author : Tuula T Teeri,B Svensson,H J Gilbert,T Feizi
Publisher : Royal Society of Chemistry
Page : 208 pages
File Size : 48,8 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847550323

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Carbohydrate Bioengineering by Tuula T Teeri,B Svensson,H J Gilbert,T Feizi Pdf

Carbohydrate bioengineering is a rapidly expanding field with many applications in medicine and industry. Presenting state-of-the-art research, Carbohydrate Bioengineering: Interdisciplinary Approaches brings together international experts on many different aspects of this burgeoning topic. Coverage includes: the engineering of glycosidases for constructive purposes; structure-function studies and protein engineering of carbohydrate-active enzymes; chemo-enzymatic carbohydrate synthesis; and trends emerging from comprehensive work on genomes and glycomes. This timely publication will be welcomed by all those needing access to the latest research in the field, including practitioners in the medicinal, chemical, food and pharmaceutical areas.

Bioinformatics for Glycobiology and Glycomics

Claus-Wilhelm von der Lieth,Thomas Luetteke,Martin Frank
Bioinformatics for Glycobiology and Glycomics Book PDF

Author : Claus-Wilhelm von der Lieth,Thomas Luetteke,Martin Frank
Publisher : John Wiley & Sons
Page : 494 pages
File Size : 49,8 Mb
Release : 2009-10-01
Category : Medical
ISBN : 0470029609

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Bioinformatics for Glycobiology and Glycomics by Claus-Wilhelm von der Lieth,Thomas Luetteke,Martin Frank Pdf

This book is the first to be dedicated to the bioinformatics of carbohydrates and glycoproteins. It provides an introduction to this emerging field of science both for the experimentalist working in glycobiology and glycomics, and also for the computer scientist looking for background information for the development of highly sophisticated algorithmic approaches. The book provides an overview of the state-of-the-art in the field, with reviews on databases, and the tools in use for analysis, interpretation, and prediction of the structures of complex carbohydrates, and demonstrates the value of bioinformatics for glycobiology. The availability of comprehensive databases and corresponding bioinformatics tools, to access and analyse the large amounts of experimental data relating to the structure of carbohydrates, will be a prerequisite for the success of the large-scale glycomics projects that aim to decipher new, so far unknown, biological functions of glycans. Efficient bioinformatics descriptions and tools can considerably enhance the efficiency of glycomics research, in terms of data quality, analysis and experimental costs. For a complete understanding of the molecular processes in which carbohydrates are involved, such as protein–carbohydrate interactions and the impact of glycosylation on protein function, knowledge of the 3D structure of the carbohydrate, the protein–carbohydrate complex, or the glycoprotein is often indispensable. This book provides a thorough introduction into methods used for conformational analysis of carbohydrates. Key features: Describes bioinformatic approaches to handle carbohydrate-active enzymes and glycosylation. Provides an overview on bioinformatics tools that facilitate analysis of carbohydrate structures. Gives introduction into molecular modelling of carbohydrate 3D structure and carbohydrates contained in the Protein Databank. Assumes only a basic knowledge of biology and bioinformatics.

Functional Proteomics

Xing Wang,Matthew Kuruc
Functional Proteomics Book PDF

Author : Xing Wang,Matthew Kuruc
Publisher : Humana Press
Page : 477 pages
File Size : 40,8 Mb
Release : 2018-10-01
Category : Science
ISBN : 1493988131

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Functional Proteomics by Xing Wang,Matthew Kuruc Pdf

This book seeks to fill in the current technology gap with a specific collection of technologies developed for the study of protein function at a proteome scale. Chapters explore topics from protein functions to other aspects of protein analysis, especially in post-translational modification, as most proteomes use this mechanism in some capacity to carry out their unique role in cellular regulation. By comparing functional proteomes, this presents a bridge to other levels of system biology research including genomics and metabolomics in order to provide readers with a relatively complete picture for how one might study the biological system of their interest. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Functional Proteomics: Methods and Protocols collects these novel technologies in the hope that new frontiers in biological research will be created, important drug targets can be identified, and clinically validated biomarkers and diagnostic tests can be further developed.

The Exocrine Pancreas

Stephen Pandol
The Exocrine Pancreas Book PDF

Author : Stephen Pandol
Publisher : Morgan & Claypool Publishers
Page : 66 pages
File Size : 54,5 Mb
Release : 2011
Category : Medical
ISBN : 9781615041381

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The Exocrine Pancreas by Stephen Pandol Pdf

The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.