Cells

Author : Thomas D. Pollard,William C. Earnshaw,Jennifer Lippincott-Schwartz,Graham Johnson
Publisher : Elsevier Health Sciences
Page : 908 pages
File Size : 40,8 Mb
Release : 2016-11-01
Category : Science
ISBN : 9780323400022

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Cell Biology E-Book by Thomas D. Pollard,William C. Earnshaw,Jennifer Lippincott-Schwartz,Graham Johnson Pdf

The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today’s students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time. Clearly written format incorporates rich illustrations, diagrams, and charts. Uses real examples to illustrate key cell biology concepts. Includes beneficial cell physiology coverage. Clinically oriented text relates cell biology to pathophysiology and medicine. Takes a mechanistic approach to molecular processes. Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing. Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation. Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing. Includes hundreds of new and updated diagrams and micrographs, plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 55,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
Page : 496 pages
File Size : 43,9 Mb
Release : 2022-10-25
Category : Medical
ISBN : 9781982117375

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The Song of the Cell by Siddhartha Mukherjee Pdf

Winner of the 2023 PROSE Award for Excellence in Biological and Life Sciences and the 2023 Chautauqua Prize! Named a New York Times Notable Book and a Best Book of the Year by The Economist, Oprah Daily, BookPage, Book Riot, the New York Public Library, and more! In The Song of the Cell, the extraordinary author of the Pulitzer Prize–winning The Emperor of All Maladies and the #1 New York Times bestseller The Gene “blends cutting-edge research, impeccable scholarship, intrepid reporting, and gorgeous prose into an encyclopedic study that reads like a literary page-turner” (Oprah Daily). Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christened them “cells.” The discovery of cells—and the reframing of the human body as a cellular ecosystem—announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer’s dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumonia—all could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies. Filled with writing so vivid, lucid, and suspenseful that complex science becomes thrilling, The Song of the Cell tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. Told in six parts, and laced with Mukherjee’s own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimate—a masterpiece on what it means to be human. “In an account both lyrical and capacious, Mukherjee takes us through an evolution of human understanding: from the seventeenth-century discovery that humans are made up of cells to our cutting-edge technologies for manipulating and deploying cells for therapeutic purposes” (The New Yorker).

Author : Eric Wong
Publisher : Axolotl Academic Publishing
Page : 283 pages
File Size : 40,7 Mb
Release : 2009
Category : Biology
ISBN : 9780985226114

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Cells: Molecules and Mechanisms by Eric Wong Pdf

"Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.

Author : Lewis Thomas
Publisher : Penguin
Page : 160 pages
File Size : 41,7 Mb
Release : 1978-02-23
Category : Science
ISBN : 9781101667057

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The Lives of a Cell by Lewis Thomas Pdf

Elegant, suggestive, and clarifying, Lewis Thomas's profoundly humane vision explores the world around us and examines the complex interdependence of all things. Extending beyond the usual limitations of biological science and into a vast and wondrous world of hidden relationships, this provocative book explores in personal, poetic essays to topics such as computers, germs, language, music, death, insects, and medicine. Lewis Thomas writes, "Once you have become permanently startled, as I am, by the realization that we are a social species, you tend to keep an eye out for the pieces of evidence that this is, by and large, good for us."

Author : Paul Trainor
Publisher : Academic Press
Page : 488 pages
File Size : 55,9 Mb
Release : 2013-11-23
Category : Science
ISBN : 9780124045866

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Neural Crest Cells by Paul Trainor Pdf

Neural Crest Cells: Evolution, Development and Disease summarizes discoveries of historical significance and provides in-depth, current analyses of the evolution of neural crest cells, their contribution to embryo development, and their roles in disease. In addition, prospects for tissue engineering, repair and regeneration are covered, offering a timely synthesis of the current knowledge in neural crest cell research. A comprehensive resource on neural crest cells for researchers studying cell biology, developmental biology, stem cells and neurobiology, Neural Crest Cells: Evolution, Development and Disease provides foundational information needed for students , practicing physicians and dentists treating patients with craniofacial defects. BMA Medical Book Awards 2014 - Highly Commended,Basic and Clinical Sciences,2014, British Medical Association Provides timely, comprehensive synthesis of the current knowledge of neural crest cells Covers the evolution and development of neural crest cells Includes content on applications for tissue engineering, repair and regeneration

Author : Christine Mummery,Anja van de Stolpe,Bernard Roelen,Hans Clevers
Publisher : Academic Press
Page : 448 pages
File Size : 43,5 Mb
Release : 2014-05-23
Category : Science
ISBN : 9780124115675

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Stem Cells by Christine Mummery,Anja van de Stolpe,Bernard Roelen,Hans Clevers Pdf

The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice

Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Publisher : National Academies Press
Page : 112 pages
File Size : 49,9 Mb
Release : 2002-01-25
Category : Science
ISBN : 9780309170420

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Stem Cells and the Future of Regenerative Medicine by Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research Pdf

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Author : Tasuku Honjo,Michael Reth,Andreas Radbruch,Frederick Alt
Publisher : Elsevier
Page : 600 pages
File Size : 44,8 Mb
Release : 2014-10-09
Category : Science
ISBN : 9780123984906

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Molecular Biology of B Cells by Tasuku Honjo,Michael Reth,Andreas Radbruch,Frederick Alt Pdf

Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. Covers signaling mechanisms regulating B cell differentiation Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab Contains studies on B cell tumors from various stages of B lymphocytes Offers an integrated view of all aspects of B cells to produce a normal immune response

Author : Michael T. Lotze,Angus W. Thomson
Publisher : Academic Press
Page : 660 pages
File Size : 53,9 Mb
Release : 2009-11-12
Category : Medical
ISBN : 0080919294

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Natural Killer Cells by Michael T. Lotze,Angus W. Thomson Pdf

Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses. The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body. The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine. Provides a broad, detailed coverage of the biology and interactions of NK cells for students, fellows, scientists, and practitioners Includes figures, histologic sections, and illustrations of the ontogeny of NK cells

Author : Huiping Liu,Justin Durla Lathia
Publisher : Elsevier
Page : 542 pages
File Size : 47,8 Mb
Release : 2016-08-16
Category : Science
ISBN : 9780128039342

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Cancer Stem Cells by Huiping Liu,Justin Durla Lathia Pdf

Cancer Stem Cells: Targeting the Roots of Cancer, Seeds of Metastasis, and Sources of Therapy Resistance introduces the basic concepts and advanced understanding of cancer stem cells, covering general overviews, organ-specific identifications, and their characteristic mechanisms. The book also explores innovative therapeutic strategies in preclinical and clinical trials to target cancer stem cells, remove the roots of cancer, eliminate the seeds of metastasis, overcome the resistance of therapies, and contribute to the eradication of cancer. The book includes contributions from leading, worldwide experts in the field, helping readers embrace new hope in their quest to eradicate cancer with emerging clinical trials on treating cancer stem cells in combination with other therapies. Provides an authoritative and complete overview of cancer stem cells Includes comprehensive coverage of current therapeutic strategies targeting cancer stem cells Deepens a reader’s technical expertise in cancer stem cell biology

Author : Rebecca Skloot
Publisher : Crown
Page : 386 pages
File Size : 44,7 Mb
Release : 2010-02-02
Category : Science
ISBN : 9780307589385

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The Immortal Life of Henrietta Lacks by Rebecca Skloot Pdf

#1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

Author : Rogers
Publisher : Academic Press
Page : 256 pages
File Size : 44,6 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780080984100

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Cells and Tissues by Rogers Pdf

Cells and Tissues: An Introduction to Histology and Cell Biology begins by explaining why histology should be studied. Some chapters follow on the techniques for studying cells and tissues, the anatomy of the cell, the epithelia, the connective tissues, and the blood. This book also covers topics on the immunity against foreign material; contractility, specifically at how it is brought about and at how the system changes in a stationary cell; and harnessing of contraction to produce movement. This text also looks into the communication systems within cells, the life and death of cells, and the histological sections of small intestine. The responses of the body to injury in the processes of inflammation and repair are also explored. This book will be useful to students starting in histology, though it does assume some elementary knowledge of biochemistry and of the structure of the mammalian body.

Author : David H. Boal
Publisher : Cambridge University Press
Page : 623 pages
File Size : 40,5 Mb
Release : 2012-01-19
Category : Science
ISBN : 9780521113762

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Mechanics of the Cell by David H. Boal Pdf

New edition exploring the mechanical features of biological cells for advanced undergraduate and graduate students in physics and biomedical engineering.

Author : Ron Milo,Rob Phillips
Publisher : Garland Science
Page : 400 pages
File Size : 43,7 Mb
Release : 2015-12-07
Category : Science
ISBN : 9781317230694

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Cell Biology by the Numbers by Ron Milo,Rob Phillips Pdf

A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid