Cerebral Circulation And Metabolism

Author : Marilyn J. Cipolla
Publisher : Biota Publishing
Page : 82 pages
File Size : 52,8 Mb
Release : 2016-07-28
Category : Medical
ISBN : 9781615047239

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The Cerebral Circulation by Marilyn J. Cipolla Pdf

This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

Author : Lars Edvinsson,E. T. MacKenzie,James McCulloch
Publisher : Raven Press (ID)
Page : 710 pages
File Size : 42,7 Mb
Release : 1993
Category : Medical
ISBN : UOM:39015029553230

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Cerebral Blood Flow and Metabolism by Lars Edvinsson,E. T. MacKenzie,James McCulloch Pdf

This text aims to provide the reader with a complete understanding of the anatomical, physiological and pharmacological bases of the cerebral circulation, its regulation in health and disease and the pathophysiological disturbances occurring in cerebrovascular disorders.

Author : T.W. Langfitt,L.C.Jr. McHenry,M. Reivich,H. Wollman
Publisher : Springer Science & Business Media
Page : 565 pages
File Size : 46,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642658143

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Cerebral Circulation and Metabolism by T.W. Langfitt,L.C.Jr. McHenry,M. Reivich,H. Wollman Pdf

This volume contains the papers presented at cluded are the concluding remarks made by the the Sixth International Symposium on Cerebral chairman of each session. The last session con Blood Flow held in Philadelphia on June 6-9, tains discussions of several topics which were felt to be of sufficient importance and interest to 1973. Since the first meeting on cerebral blood flow, held in Lund in 1964, the number of par warrant extended consideration. These con ticipants in these symposia has steadily increased cerned the questions of neurogenic control of until at this meeting it was necessary to conduct the cerebral circulation, the role of failure of simultaneous sessions. The interest and effort reperfusion in cerebral ischemia, and a discus sion of invasive and noninvasive methods of directed toward problems concerned with cere bral circulation and metabolism, as well as the CBF determination. Owing to the large number increasing sophistication applied to these prob of papers included in this book and the interests lems, are amply demonstrated in this book. of rapid publication, it was not possible to in A wide variety of topics was discussed at the clude the discussions of each paper. The orga symposium with major emphasis on the basic nizers regret the necessity of this decision but aspects of the control of cerebral circulation and wish to thank the many participants who con metabolism.

Author : Alexander Murray Harper,Sheila Jennett
Publisher : Manchester University Press
Page : 132 pages
File Size : 55,9 Mb
Release : 1990
Category : Brain
ISBN : 0719028930

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Cerebral Blood Flow and Metabolism by Alexander Murray Harper,Sheila Jennett Pdf

An outgrowth of a 1987 teaching seminar at the U. of Glasgow, designed to update physiologists--particularly those in teaching positions--on the recent developments in the relation of cerebral blood flow to metabolism. The five papers might also be useful directly to graduate medical students. Distributed in the US by St. Martin's Press. Annotation copyrighted by Book News, Inc., Portland, OR

Author : Payne Stephen John
Publisher : World Scientific
Page : 468 pages
File Size : 40,5 Mb
Release : 2017-10-06
Category : Medical
ISBN : 9789813220584

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Cerebral Blood Flow And Metabolism: A Quantitative Approach by Payne Stephen John Pdf

This book describes the way in which the human brain is supplied with blood and how the brain uses this to provide nutrients, primarily oxygen and glucose, to brain cells in order to maintain healthy brain function. In particular, it focuses on the quantitative nature of blood flow and metabolism. The book covers models of blood flow and metabolism and how these can be measured using a variety of imaging and non-imaging techniques. It also examines how cerebral blood flow is controlled in response to a wide variety of challenges and how it changes with normal physiological variation and in response to a large number of pathological conditions, including stroke and dementia. As the first substantial book for over ten years in a fast-changing field, it highlights how the subject has progressed in the last couple of decades. It tackles the subject in a quantitative way, underlining its importance in both technical and clinical fields. Audiences with a technical or clinical background, especially researchers and postgraduate students in biomedical engineering or medicine, will find this a valuable read. Contents: Physiology of Blood Flow and MetabolismModels of Blood Flow and MetabolismGlobal Control of Blood FlowLocal Control of PerfusionExternally-based MeasurementsInternally-based MeasurementsGlobal Changes in Cerebral Blood Flow and MetabolismLocal Changes in Cerebral Blood Flow and MetabolismConclusions Readership: Researchers and postgraduate students in biomedical engineering and medicine. Keywords: Brain;Haemodynamics;Vascular;Neurovascular;Autoregulation;Brain imagingReview: Key Features: Focus on quantitative measurements and models, and their application in clinical practiceCoverage aimed at both technical and clinical audienceUp-to-date coverage of a very broad field, with no recent equivalent text

Author : A. Hartmann,S. Hoyer
Publisher : Springer Science & Business Media
Page : 631 pages
File Size : 40,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642700545

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Cerebral Blood Flow and Metabolism Measurement by A. Hartmann,S. Hoyer Pdf

At the present time several techniques are available for studying quantitatively global and regional blood flow and metabolism of the human brain. How ever, many scientists working in the clinical and research field who would like to use these tools for their investigations may be less familiar with the indi cations and limitations of the individual methods. The rapid development of both modern imaging techniques and new tracers may have led to some con fusion in answering the question as to which method is appropriate to solve the diagnostic problem of an individuum with brain disease. Scepticism and ignorance as to the methods to be used as tools in differential diagnosis of brain disorders may have prevented their widespread introduction into clinical practice. Thus, the significance of circulatory and metabolic parameters involved in the majority of diseases of the central nervous system may have been overlooked. The contributions compiled in this book describe in detail the individual techniques, outline their indications and limitations and deal in particular with newer methods such as the atraumatic 133Xe technique, stable xenon tomogra phy, three-dimensional techniques such as 133Xe single photon emission tomog raphy and N-isopropyl-P23-iodoamphetamine. Positron emission tomography studies provide information on function and metabolism, particularly that of oxygen and glucose, in regional brain areas of interest. Nuclear magnetic reso nance may be a promising method for studying metabolic parameters; however, accurate circulation measurements can not be performed at present.

Author : Alexander Murray Harper
Publisher : Unknown
Page : 604 pages
File Size : 40,6 Mb
Release : 1975
Category : Medical
ISBN : UOM:39015003803650

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Blood Flow and Metabolism in the Brain by Alexander Murray Harper Pdf

Author : M. J. Purves
Publisher : CUP Archive
Page : 448 pages
File Size : 41,7 Mb
Release : 1972-05-25
Category : Medical
ISBN : 0521083001

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The Physiology of the Cerebral Circulation by M. J. Purves Pdf

Author : Pan-Dong Ryu,Joseph C. LaManna,David K. Harrison,Sang-Suk Lee
Publisher : Springer Nature
Page : 431 pages
File Size : 49,5 Mb
Release : 2019-12-31
Category : Medical
ISBN : 9783030344610

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Oxygen Transport to Tissue XLI by Pan-Dong Ryu,Joseph C. LaManna,David K. Harrison,Sang-Suk Lee Pdf

This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medicine. The book is composed of the following 6 parts: Brain Oxygenation and Function, Tumor Oxygenation and Metabolism, Muscle Oxygenation and Sports Medicine, Cell Metabolism and Tissue Oxygenation, Methodology of O2 Measurements, and Special Topics. The articles in this book have been presented at the 46th annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2018) held in Seoul, Republic of Korea, from July 1 to July 5, 2018. Academics, clinical and industry researchers, engineers, as well as graduate students who are interested in oxygen transport to tissue will find this book a great reference and a useful learning resource.

Author : Georg E. Cold
Publisher : Springer Science & Business Media
Page : 74 pages
File Size : 49,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709191019

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Cerebral Blood Flow in Acute Head Injury by Georg E. Cold Pdf

During the last decade a multitude of studies concerning the dynamic changes in cerebral blood flow (CBF), cerebral metabolic rate of oxygen (CMRO2), and intracranial pressure (ICP) in the acute phase after head injury have been published. These studies have been supplemented with studies of cerebral autoregulation, CO2 reactivity and barbiturate reactivity. Other investigations include studies of cerebrospinal fluid pH, bicarbonate, lactate and pyruvate. In this book experimental and clinical studies of the dynamic changes in CBF, CMRO2, CO2 reactivity and barbiturate reactivity are reviewed. The author's own clinical studies of the dynamic changes in CBF and cerebral metabolism are summarized and discussed, and the therapeutical implication as regards the use of artificial hyperventilation, sedation with barbiturate and mannitol treatment are discussed.

Author : Anish Bhardwaj,Marek A. Mirski,John A. Ulatowski
Publisher : Springer Science & Business Media
Page : 337 pages
File Size : 42,5 Mb
Release : 2004-05-25
Category : Medical
ISBN : 9781592597727

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Handbook of Neurocritical Care by Anish Bhardwaj,Marek A. Mirski,John A. Ulatowski Pdf

Neurocritical care as a subspecialty has grown rapidly over the last 20 years with the advent of newer monitoring and diagnostic techniques and therapeutic modalities in a variety of brain and spinal cord injury paradigms. This handbook will serve as a quick reference guide to all health care providers in a neurocritical care setting. Since time is of the essence in the rapid diagnosis and timely therapeutic interventions for these patients, this book provides an algorithmic approach to making a clinical diagnosis using ancillary investigations to confirm the diagnosis and provide appropriate management of acute neurologic diseases. Tables and illustrations help provide a quick and easy bedside reference and give a practical approach to the management of these patients.

Author : Janet V. Passonneau
Publisher : Unknown
Page : 440 pages
File Size : 51,5 Mb
Release : 1980
Category : Brain
ISBN : UOM:39015000256910

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Cerebral Metabolism and Neural Function by Janet V. Passonneau Pdf

Author : Jorge Cervós-Navarro,Emmanuel Fritschka
Publisher : Raven Press (ID)
Page : 510 pages
File Size : 53,6 Mb
Release : 1981
Category : Brain
ISBN : UCAL:B4513764

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Cerebral Microcirculation and Metabolism by Jorge Cervós-Navarro,Emmanuel Fritschka Pdf

Author : Andreas W. Unterberg,Gerd-Helge Schneider,Wolfgang R. Lanksch
Publisher : Springer Science & Business Media
Page : 364 pages
File Size : 53,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709193020

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Monitoring of Cerebral Blood Flow and Metabolism in Intensive Care by Andreas W. Unterberg,Gerd-Helge Schneider,Wolfgang R. Lanksch Pdf

Until recently, monitoring of cerebral blood flow and metabolism was an unattained goal. Determination of cerebral blood flow was limited to intermittent measurements and particularly difficult to perform in critically ill patients. Meanwhile there are techniques available, however, to monitor cerebral blood flow and cerebral oxygenation, both globally and regionally. Therefore we thought it worthwhile to discuss these new continuous techniques and to compare them with well-known techniques which discontinuously measure CBF. For that purpose, an international workshop with some leading experts in the field was held in October 1992 in Berlin. The workshop consisted of about 20 lectures, either reviews on a special topic, or latest results. These contributions were given by invitation and were extensively discussed. Unfortunately it is impossible to reproduce the discussions. On the other hand, all speakers delivered a manuscript promptly after the meeting so that we were able to edit them within a short time. Since monitoring of cerebral blood flow in intensive care is a rapidly growing and changing topic, the written contributions should be quickly available. Authors, editors and publishers have tried to come close to this ideal. As editors we would like to thank the authors and the publishers who enabled us to come out with this volume of the proceedings as early as possible.

Author : Matthew E. Cross,Emma V. E. Plunkett
Publisher : Cambridge University Press
Page : 439 pages
File Size : 40,9 Mb
Release : 2014-03-06
Category : Medical
ISBN : 9781107615885

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Physics, Pharmacology and Physiology for Anaesthetists by Matthew E. Cross,Emma V. E. Plunkett Pdf

A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams.