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Challenges in Pediatric Kidney Transplantation by Katherine E. Twombley Pdf
This book provides a comprehensive overview of the unique challenges inherent in pediatric kidney transplantation. The text reviews the problems faced during each stage of the kidney transplantation process, including the occurrence of infections during the pre-transplant stage, surgical challenges during the actual transplantation, and medication issues during the post-transplant stage. The book also features high-yield case presentations of typical pediatric transplant scenarios, from the pre-transplant management of a child with CAKUT to the evaluation and treatment of antibody mediated rejection in children. Written by experts in the field, Challenges in Pediatric Kidney Transplantation: A Practical Guide is a valuable resource for clinicians, practitioners, and trainees who manage or are interested in this challenging group of patients.
Pediatric Renal Transplantation by Leonard Curtis Hymes Pdf
The role of immunosuppression is essential to maintain the integrity of a renal transplant by preventing acute rejection. Among adult patients with solid organ transplants, standard immunosuppression does not vary among the major transplant centres in the USA and Europe, and consists of corticosteroids, calcineurin inhibitors and mycophenolic acid. However, children with renal transplants are more susceptible than adults to suffer adverse events related to this standard protocol, including short stature, nephrotoxicity, lymph proliferative disease and infections. For this reason, paediatric nephrologists have explored alternatives to standard immunosuppression while still maintaining acceptable graft outcomes. This book will explore this theme, which will include several chapters that present alternative immunosuppression protocol, in addition to other chapters that address challenging and controversial issues in paediatric renal transplantation. The first three chapters will describe immunosuppression protocols which may have specific benefits in children with renal allografts compared to standard regimens in adults. This includes the use of steroid-avoidance, which obviates many of the problems associated with corticosteroid use in children especially short stature and obesity. Secondly, the mTOR inhibitor Sirolimus is thoroughly discussed, including the potential benefits of this agent because of its lack of nephrotoxicity and possible anti-neoplastic properties. Lastly, induction therapy with Alemtuzumab is described, including recent studies that suggest that this agent may have definite benefits in children compared to standard induction with anti-thymocyte globulin.
Kidney Transplantation by Massimiliano Veroux,Pierfrancesco Veroux Pdf
This e-book is an overview of recent advances in the realm of kidney transplantation. The volume discusses developments in surgical procedures while presenting a perspective on possibilities for kidney transplant research in the future. The e-book is a c
Author : Amir H. Tejani,Richard N. Fine Publisher : Wiley-Liss Page : 576 pages File Size : 43,5 Mb Release : 1994-08-16 Category : Medical ISBN : UOM:39015032714456
Pediatric Renal Transplantation by Amir H. Tejani,Richard N. Fine Pdf
A detailed, contributed reference offering broad coverage of renal transplantation in children. Diagnosis, the patient's medical management, operative methods, surgical and medical complications, donor selection, immunosuppression, late effects on growth and development and psychosocial factors are among the topics discussed. Features a chapter on how to set up and manage a pediatric renal transplant program.
Challenges and Controversies in Kidney Transplantation by Sandip Kapur Pdf
Challenges and Controversies in Kidney Transplantation highlights the most up-to-date strategies for successfully managing high-risk kidney transplant recipients, as well as detailed, innovative strategies to increase transplant opportunities for patients requiring kidney transplantation. The book is divided into two major sections; firstly, Maximizing Transplant Opportunities, and second, Considerations for Unique/High Risk Patient Populations focusing on management of select patient populations, such as children, the elderly, HIV, Hepatitis C positive patents, highly sensitized patients, and patients who develop post-transplant polyomavirus nephropathy. Surgical topics include Laparoendoscopic Single Site and Robotic Donor Nephrectomy as minimally invasive surgical procedures to increase living donation, and the use of Paediatric Donor Kidneys in deceased donor kidney transplantation. In addition, Challenges and Controversies in Kidney Transplantation also features discussion on the most difficult clinical management issues confronting Kidney Transplantation today, making it a relevant and essential reference for nephrologists, neurologists and residents. Key Points Concise and comprehensive guide to problems associated with kidney transplantation Full colour illustrations Authored by Sandip Kapur, Professor of Surgery at Weill Medical College – Cornell University, USA
This fifth edition of KIDNEY TRANSPLANTATION remains the most comprehensive and definitive text on all aspects of renal transplantation as well as the psychological and ethical issues involved. Almost every chapter has been revised or rewritten by new authors, to incorporate the most essential and up-to-date information.
Author : Stephen P. Dunn,Abigail E. Martin Publisher : Springer Page : 0 pages File Size : 49,8 Mb Release : 2016-02-14 Category : Medical ISBN : 3319072838
Solid Organ Transplantation in Infants and Children by Stephen P. Dunn,Abigail E. Martin Pdf
A new textbook of transplantation for infants and children is needed that is at least a first effort at achieving standard work in this field. Solid Organ Transplantation in Infants and Children provides a broad view of the current practice of solid organ transplantation in pediatric patients. It focuses on best practice and measureable outcomes whenever possible. It provides direct guidance for standard work in this broad and young field of clinical work. It portrays the regulatory environment in which this work occurs and the specific program requirements for each clinical program. Organized in two volumes, the first volume is devoted to the pediatric patient and their particular needs or concerns. This volume also contains information on the regulatory environment and pediatric program specific requirements. The second volume is devoted to the standard work in each solid organ transplanted. These volumes will be very useful for every practicing pediatric transplant program in the United States and Canada and much of the developed world. By reading these volumes, the reader will gain a firm understanding and practical knowledge of standard work in solid organ transplantation and the regulatory environment and requirements of programs to do that work.
Pediatric Kidney Disease by Franz Schaefer,Larry A. Greenbaum Pdf
The extensively revised third edition of this text offers an in-depth practical guide to clinical conditions encountered in pediatric nephrology. Extensively updated disease-specific chapters offer detailed coverage of relevant basic science, diagnostic work-up, laboratory evaluation methods, appropriate management options and potential complications. Topics covered include disorders of renal development, glomerular disorders, the kidney and systemic disease, renal tubular disorders, tubulointerstitial disease, urinary tract disorders, acute kidney injury, chronic kidney disease, dialysis, kidney transplantation and hypertension. Information is also provided on important related issues, including the genetic origins of diseases, the role of complement in the pathogenesis of kidney disease, and pharmacological aspects related to the kidney. Pediatric Kidney Disease comprehensively reviews a range of clinical conditions encountered in pediatric nephrology, assisting the reader to develop their skills and improve their clinical decision-making. It is a vital resource for trainees and practicing clinicians alike and a useful reference for those preparing for pediatric nephrology board examinations.
Kidney Transplantation by Peter Morris,Stuart J. Knechtle Pdf
Updated to reflect today’s practice guidelines, the new edition of this comprehensive text remains the definitive resource on all aspects of renal transplantation, including immunological, pathological, psychological and ethical considerations. It examines evaluation, management, and procurement of living and deceased donor kidneys, the selection of suitable recipients, interpretation of graft dysfunction, and expected survival based upon a large database of information. There are comprehensive chapters on pediatric renal transplantation and on renal transplantation in the developing world. Extensive tables and figures and comprehensive lists of references with each chapter enhance its value to the transplant team. A multidisciplinary approach from internationally renowned contributors from around the world-many new to this edition-offers practice-applicable guidance for all members of the transplant team, with coverage encompassing applied science, clinical information, and surgical procedures. This 6th edition remains the balanced reference you need to stay apprised of issues important to successful kidney transplantation. Provides a comprehensive description of surgical techniques, immunosuppressive methods, outcomes, risks, and medical considerations related to kidney transplantation, both in adults and children, in one convenient reference. Presents more than 335 superb illustrations-50 in full color-that demonstrate key concepts and nuances of techniques. Features a multidisciplinary approach from contributors from around the world-many new to this edition-offers practice-applicable guidance for all members of the transplant team, with coverage encompassing applied science, clinical information, and surgical procedures. Offers evidence-based decision making advice in renal transplantation-supported by a wealth of data in chapters written by internationally recognized experts-to help you make the most informed clinical decisions. Offers new tables and figures as well as revised and updated chapters that report new data and present current practice guidelines. Features a new chapter on transplantation in the sensitized patient to assist you with transplant cases that present unique challenges. Describes the latest preclinical and clinical immunosuppressive strategies, to help you see the link between clinical issues and the basic sciences. Offers tissue typing methodology updates, equipping you with the newest methods of assessing immune responses to the kidney. Features a new chapter on chronic allograft nephropathy.
Ethical Issues in Pediatric Organ Transplantation by Rebecca A. Greenberg,Aviva M. Goldberg,David Rodríguez-Arias Pdf
This book offers a theoretical and practical overview of the specific ethical and legal issues in pediatric organ transplantation. Written by a team of leading experts, Ethical Issues in Pediatric Organ Transplantation addresses those difficult ethical questions concerning clinical, organizational, legal and policy issues including donor, recipient and allocation issues. Challenging topics, including children as donors, donation after cardiac death, misattributed paternity, familial conflicts of interest, developmental disability as a listing criteria, small bowel transplant, and considerations in navigating the media are discussed. It serves as a fundamental handbook and resource for pediatricians, transplant health care professionals, trainees, graduate students, scholars, practitioners of bioethics and health policy makers.
Richard N. Fine,Steven A. Webber,William E. Harmon,Deirdre A. Kelly,Kim M. Olthoff
Author : Richard N. Fine,Steven A. Webber,William E. Harmon,Deirdre A. Kelly,Kim M. Olthoff Publisher : John Wiley & Sons Page : 488 pages File Size : 52,8 Mb Release : 2009-04-08 Category : Medical ISBN : 9781444312737
Pediatric Solid Organ Transplantation by Richard N. Fine,Steven A. Webber,William E. Harmon,Deirdre A. Kelly,Kim M. Olthoff Pdf
Pediatric Solid Organ Transplantation is acomprehensive and succinct text on all aspects of pediatric solidorgan transplantation. It provides a ready source of reference, toboth the basic science and organ specific surgical technique andafter care. This second edition has been extensively updated inlight of recent developments in this rapidly advancing area. The only textbook devoted to the field of pediatrictransplantation A definitive reference for all those interested in improvingthe care and quality of life of children undergoing solid organtransplantation Section on immunosuppression has been expanded by four chaptersto include sections on; - mechanisms of action - therapies for the sensitized patient - post-transplant lymphoproliferative disorders - organ toxicities of immunosuppressive therapy A new section has been added on the many topics related toquality of life that effect survivors of pediatrictransplantation International editorial and contributor team represents a widegeographical range and contains both recognized leaders andemerging experts Whether you are an established sub-specialist in pediatrictransplantation, a transplant surgeon, or a pediatric specialist ina related area, this book will answer all your questions about careof the pediatric patient before, during, and aftertransplantation.
Kidney Transplantation, Bioengineering, and Regeneration by Giuseppe Orlando,Giuseppe Remuzzi,David F. Williams Pdf
Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney. Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function
