Characterization Of Pharmaceutical Nano And Microsystems

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Characterization of Pharmaceutical Nano- and Microsystems

Author : Leena Peltonen
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 55,7 Mb
Release : 2020-10-16
Category : Science
ISBN : 9781119414032

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Characterization of Pharmaceutical Nano- and Microsystems by Leena Peltonen Pdf

Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines. Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics: An introduction to the analytical tools applied to determine particle size, morphology, and shape Common chemical approaches to drug system characterization A description of solid-state characterization of drug systems Drug release and permeation studies Toxicity and safety issues The interaction of drug particles with cells Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.

Characterization of Pharmaceutical Nano- and Microsystems

Author : Leena Peltonen
Publisher : John Wiley & Sons
Page : 410 pages
File Size : 42,8 Mb
Release : 2020-12-21
Category : Science
ISBN : 9781119414049

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Characterization of Pharmaceutical Nano- and Microsystems by Leena Peltonen Pdf

Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines. Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics: An introduction to the analytical tools applied to determine particle size, morphology, and shape Common chemical approaches to drug system characterization A description of solid-state characterization of drug systems Drug release and permeation studies Toxicity and safety issues The interaction of drug particles with cells Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.

Characterization and Biology of Nanomaterials for Drug Delivery

Author : Shyam Mohapatra,Shivendu Ranjan,Nandita Dasgupta,Raghvendra Kumar,Sabu Thomas
Publisher : Elsevier
Page : 684 pages
File Size : 40,9 Mb
Release : 2018-10-05
Category : Science
ISBN : 9780128140321

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Characterization and Biology of Nanomaterials for Drug Delivery by Shyam Mohapatra,Shivendu Ranjan,Nandita Dasgupta,Raghvendra Kumar,Sabu Thomas Pdf

Characterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery describes the techniques successfully employed for the application of nanocarriers loaded with the antioxidant enzyme, catalase, and thus targeted to endothelial cells. Methods of nanocarrier synthesis, loading within various systems, and the characterization of nanocarriers for targeting activities are covered, as are their advantages, disadvantages and applications. Reflecting the interdisciplinary nature of the subject matter, this book includes contributions by experts from different fields, all with various backgrounds and expertise. It will appeal to researchers and students from different disciplines, such as materials science, technology and various biomedical fields. Enables readers from different fields to access recent research and protocols across traditional boundaries Focuses on protocols and techniques, as well as the knowledge base of the field, thus enabling those in R&D to learn about, and successfully deploy, cutting-edge techniques Explores both current and emerging classes of nanomaterials, along with their fundamentals and applications

Drug Delivery Nanoparticles Formulation and Characterization

Author : Yashwant Pathak,Deepak Thassu
Publisher : CRC Press
Page : 416 pages
File Size : 45,6 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420078053

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Drug Delivery Nanoparticles Formulation and Characterization by Yashwant Pathak,Deepak Thassu Pdf

Exploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.This comprehensive guide features:Process Analytical Techniques (PAT) used in manufacturing Na

Characterization of Nanoparticles Intended for Drug Delivery

Author : Scott E. McNeil
Publisher : Humana Press
Page : 256 pages
File Size : 50,6 Mb
Release : 2017-10-20
Category : Medical
ISBN : 1493973509

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Characterization of Nanoparticles Intended for Drug Delivery by Scott E. McNeil Pdf

This second edition volume expands on the first edition by providing up-to-date protocols to characterize nanomaterials used as drug delivery agents. The chapters in this book are divided into 5 parts and cover topics such as: advances and obstacles in nanomedicine research; methods to test sterility and endotoxin, physicochemical features, immunological effects, drug release, and in vivo efficacy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Characterization of Nanoparticles Intended for Drug Delivery, Second Edition is a valuable tool for researchers and pharmaceutical and biotechnology developers who are evaluating the clinical potential of nanomedicines in preclinical studies.>

Characterization of Micro and Nanoparticles for Biomedical Applications

Author : Ranjita Shegokar,Eliana B. Souto
Publisher : Elsevier
Page : 0 pages
File Size : 55,8 Mb
Release : 2023-08-01
Category : Science
ISBN : 9780323961394

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Characterization of Micro and Nanoparticles for Biomedical Applications by Ranjita Shegokar,Eliana B. Souto Pdf

Any generic or innovative pharmaceutical product requires to undergo an extensive characterization cycle (in-vitro, ex-vivo, cell lines based evaluation) before getting to preclinical and clinical stages and eventually to be "eligible" for marketing authorization. The expectation of "high-quality data" is essentially dependent on the analytical methodology applied for characterization. For routine products like tablets, capsules, and solutions, the regulatory guidelines, product-specific monographs, and pharmacopoeial annexures are set and are "standard of operation." In addition, GMP/ISO guidelines support industries, academicians, and contract labs to evaluate, document, and validate the routine product to get qualified. However, for nano-micro pharmaceuticals, the regulatory guidelines are still evolving and are very much dependent on the literature data and "latest draft" reports from experts and regulatory body discussions. This book aims to provide one-stop resources on all the analytical techniques used in the field of micro and nanoparticles evaluation and characterization. The chapters will bring together knowledge on current analytical methodologies, limitations, and advances in the in vitro analysis field. Characterization of Micro and Nanoparticles for Biomedical Applications is a helping guide for industry researchers, academicians, regulatory experts, and material scientists working in this field of pharmaceuticals, cosmeceuticals, nutraceuticals, agriculture, food, fragrance, and chemical industry. The equipment industry can benefit from its innovations by understanding the needs of researchers and the challenges of current techniques. Covers the entire landscape of in vitro analytical techniques applied for characterization and analysis of micro-and nanoparticles in biomedicine Examines limitations and challenges of currently used methodologies Discusses new advances in the field of micro-nano characterization

Quality Control Applications in the Pharmaceutical and Medical Device Manufacturing Industry

Author : Carrillo-Cedillo, Eugenia Gabriela,Arredondo-Soto, Karina Cecilia,Palomino-Vizcaino, Kenia,Magaña-Badilla, Héctor Alfonso
Publisher : IGI Global
Page : 298 pages
File Size : 54,7 Mb
Release : 2022-03-18
Category : Technology & Engineering
ISBN : 9781799896159

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Quality Control Applications in the Pharmaceutical and Medical Device Manufacturing Industry by Carrillo-Cedillo, Eugenia Gabriela,Arredondo-Soto, Karina Cecilia,Palomino-Vizcaino, Kenia,Magaña-Badilla, Héctor Alfonso Pdf

Quality control in pharmaceutical products and medical devices is vital for users as failing to comply with national and international regulations can lead to accidents that could easily be avoided. For this reason, manufacturing a quality medical product will support patient safety. Microbiologists working in both the pharmaceutical and medical device industries face considerable challenges in keeping abreast of the myriad microbiological references available to them and the continuously evolving regulatory requirements. Quality Control Applications in the Pharmaceutical and Medical Device Manufacturing Industry presents the importance of quality control in pharmaceutical products and medical devices, which must have very high-quality standards to not cause problems to the health of patients. It reinforces and updates the knowledge of analytical, instrumental, and biological methods to demonstrate the correct quality control and good manufacturing practice for pharmaceutical products and medical devices. Covering topics such as pharmaceutical nano systems, machine learning, and software validation, this book is an essential resource for managers, engineers, supervisors, pharmacists, chemists, academicians, and researchers.

Nanoparticle Therapeutics

Author : Prashant Kesharwani,Kamalinder K. Singh
Publisher : Academic Press
Page : 674 pages
File Size : 51,6 Mb
Release : 2021-11-06
Category : Technology & Engineering
ISBN : 9780128209189

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Nanoparticle Therapeutics by Prashant Kesharwani,Kamalinder K. Singh Pdf

Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states. This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful. Brings together the novel applications of nanotechnology in biological fields Explores perspectives on technologies through highly organized tables, illustrative figures and flow charts Addresses key multidisciplinary challenges faced by nanotechnologists to foster collaboration among biologists, chemists, physicists, engineers and clinicians

Advances in Nanotechnology-Based Drug Delivery Systems

Author : Anupam Das Talukdar,Satyajit Dey Sarker,Jayanta Kumar Patra
Publisher : Elsevier
Page : 672 pages
File Size : 42,9 Mb
Release : 2022-06-06
Category : Technology & Engineering
ISBN : 9780323904148

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Advances in Nanotechnology-Based Drug Delivery Systems by Anupam Das Talukdar,Satyajit Dey Sarker,Jayanta Kumar Patra Pdf

Advances in Nanotechnology-Based Drug Delivery Systems covers the core concepts and latest research regarding the use of nanoscale materials for the development and application of drug delivery systems. The book introduces the reader to nanotechnology in drug delivery, covering the synthesis, encapsulation techniques, characterization and key properties of nanoscale drug delivery systems. Later chapters review the broad range of target applications, including site-specific delivery of drugs for cardiovascular disease, cancer, bacterial infection, bone regeneration. and much more. This book helps translate advanced research into a clinical setting, analyzing the toxicity and health and safety challenges associated with utilizing nanotechnology in biomedicine. This will be a useful reference for those interested in nano-sized drug delivery in biomedicine, including academics and researchers in materials science, biomedical engineering, pharmaceutical science and related disciplines. Provides a clear introduction to nanotechnology in drug delivery, covering key principles, synthesis, characterization and unique properties of nanoscale materials for drug delivery systems“/li> Discusses preclinical, clinical and patented nano-drug delivery systems, enabling the reader to grasp the current state-of-the-art and market Covers a broad range of targets for nanoscale drug delivery systems, such as in neurological disorders, oral disease, renal disease, cancer, skin protection, and much more

Nanomaterials for Clinical Applications

Author : Costas Demetzos,Natassa Pippa
Publisher : Elsevier
Page : 322 pages
File Size : 49,9 Mb
Release : 2020-02-14
Category : Technology & Engineering
ISBN : 9780128168769

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Nanomaterials for Clinical Applications by Costas Demetzos,Natassa Pippa Pdf

Nanomaterials in Clinical Medicine: Case Studies in Nanomedicines focuses on the nanomaterials that can be formulated as drug delivery vehicles, such as liposomes, micelles, nanoemulsions and nanogels. Their physicochemical, morphological, thermo-dynamical and nanotoxicological properties are analyzed with respect to the design and development of drug delivery nanosystems for the encapsulation of an active pharmaceutical ingredient and its controlled release. Each chapter covers basic properties, the nanosystem (e.g., liposomes), the added value in drug delivery and targeting, and future perspectives. Case studies and examples of how nanomaterials are being used in clinical medicine, including marketed liposomal medicines and medical utility and regimens are also included. Particular attention is given to new nanocarriers, such as elastic liposomes, lipid polymeric hybrid nanoparticles, organogel, nanofibers carbon nanomaterials, quantum dots and inorganic nanoparticles. This book is an important information source for those wanting to increase their understanding of what major nanomaterials are being used to create more effective drug delivery systems. Summarizes the major nanomaterials used in clinical medicine, explaining how their properties make them suitable for this purpose Explains how nanomaterials are used to create increasingly efficient drug delivery vehicles Includes real-life examples, demonstrating how nanomaterials are being used in medical practice

Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 696 pages
File Size : 53,9 Mb
Release : 2017-12-11
Category : Science
ISBN : 9780128136300

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Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology by Alexandru Mihai Grumezescu Pdf

Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology focuses on the fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. In particular, the following aspects of nanoparticle preparation methods are discussed: the need for less toxic reagents, simplification of the procedure to allow economic scale-up, and optimization to improve yield and entrapment efficiency. Written by a diverse range of international researchers, the chapters examine characterization and manufacturing of nanomaterials for pharmaceutical applications. Regulatory and policy aspects are also discussed. This book is a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about how nanomaterials can best be utilized. Shows how nanomanufacturing techniques can help to create more effective, cheaper pharmaceutical products Explores how nanofabrication techniques developed in the lab have been translated to commercial applications in recent years Explains safety and regulatory aspects of the use of nanomanufacturing processes in the pharmaceutical industry

Pharmaceutical Nanotechnology, 2 Volumes

Author : Jean Cornier,Andrew Owen,Arno Kwade,Marcel Van de Voorde
Publisher : John Wiley & Sons
Page : 804 pages
File Size : 42,9 Mb
Release : 2017-06-19
Category : Technology & Engineering
ISBN : 9783527340545

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Pharmaceutical Nanotechnology, 2 Volumes by Jean Cornier,Andrew Owen,Arno Kwade,Marcel Van de Voorde Pdf

With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book. Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!

Pharmaceutical Nanotechnology

Author : Volkmar Weissig,Tamer Elbayoumi
Publisher : Humana
Page : 398 pages
File Size : 45,8 Mb
Release : 2020-08-14
Category : Medical
ISBN : 1493995189

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Pharmaceutical Nanotechnology by Volkmar Weissig,Tamer Elbayoumi Pdf

This volume details protocols on formulation, surface modification, characterization, and application of a variety of pharmaceutical nanocarriers such as micelles, nanoparticles, dendrimers, carbon dots, polymersomes, and others. Chapters are targeted toward investigators working in academic and industrial laboratories conducting research in the broad field of pharmaceutical sciences, with an emphasis on drug delivery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Pharmaceutical Nanotechnology: Basic Protocols aims to be a source of inspiration to all investigators who are interested in the potential of the merger of nanotechnology with pharmaceutical sciences.

Nanoparticles

Author : Maneesha Pande,Ashok N. Bhaskarwar
Publisher : Momentum Press
Page : 224 pages
File Size : 41,5 Mb
Release : 2016-01-13
Category : Technology & Engineering
ISBN : 9781606506318

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Nanoparticles by Maneesha Pande,Ashok N. Bhaskarwar Pdf

Nanotechnology and nanoparticles have emerged as an important tool towards improving cancer therapeutics and diagnostics. Recognizing the indispensable role of nanoparticles, specifically in targeted delivery of chemotherapeutic and other anti-cancer agents to tumors, this book provides a comprehensive account of the different methods used for the preparation of nanoparticles, including the mechanism behind each method, for a beginner in the field. The authors describe he commonly used methods of physical post-synthesis characterization, as well as the toxicity aspects of nanoparticles, particularly the effect of nanoparticles on different systems of the human body. Appreciating the interdisciplinary nature of nanotechnology applications in cancer drug delivery, a brief description of the genesis and growth of a tumor has also been included in the book.

Nanomedicine in Drug Delivery

Author : Arun Kumar,Heidi M. Mansour,Adam Friedman,Eric R. Blough
Publisher : CRC Press
Page : 465 pages
File Size : 43,5 Mb
Release : 2013-06-05
Category : Medical
ISBN : 9781466506169

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Nanomedicine in Drug Delivery by Arun Kumar,Heidi M. Mansour,Adam Friedman,Eric R. Blough Pdf

There is a clear need for innovative technologies to improve the delivery of therapeutic and diagnostic agents in the body. Recent breakthroughs in nanomedicine are now making it possible to deliver drugs and therapeutic proteins to local areas of disease or tumors to maximize clinical benefit while limiting unwanted side effects. Nanomedicine in Drug Delivery gives an overview of aspects of nanomedicine to help readers design and develop novel drug delivery systems and devices that build on nanoscale technologies. Featuring contributions by leading researchers from around the world, the book examines: The integration of nanoparticles with therapeutic agents The synthesis and characterization of nanoencapsulated drug particles Targeted pulmonary nanomedicine delivery using inhalation aerosols The use of biological systems—bacteria, cells, viruses, and virus-like particles—as carriers to deliver nanoparticles Nanodermatology and the role of nanotechnology in the diagnosis and treatment of skin disease Nanoparticles for the delivery of small molecules, such as for gene and vaccine delivery The use of nanotechnologies to modulate and modify wound healing Nanoparticles in bioimaging, including magnetic resonance, computed tomography, and molecular imaging Nanoparticles to enhance the efficiency of existing anticancer drugs The development of nanoparticle formulations Nanoparticles for ocular drug delivery Nanoparticle toxicity, including routes of exposure and mechanisms of toxicity The use of animal and cellular models in nanoparticles safety studies With its practical focus on the design, synthesis, and application of nanomedicine in drug delivery, this book is a valuable resource for clinical researchers and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner. It explores a wide range of promising approaches for the diagnosis and treatment of diseases using cutting-edge nanotechnologies.