Chemical Carcinogenesis And Mutagenesis I

Author : Anonim
Publisher : Springer
Page : 604 pages
File Size : 53,5 Mb
Release : 2011-12-21
Category : Medical
ISBN : 3642747760

Get Book

Chemical Carcinogenesis and Mutagenesis I by Anonim Pdf

I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin Madison. I immediately started to work with the carcinogenic aminoazo dyes un der the direction of Professor CARL BAUMANN. In 1942 I joined a fellow graduate student, ELIZABE1H CAVERT, in marriage and we soon commenced a joyous part nership in research on chemical carcinogenesis at the McArdle Laboratory for Cancer Research in the University of Wisconsin Medical School in Madison. This collaboration lasted 45 years. I am very grateful that this volume is dedi cated to the memory of Elizabeth. The important and varied topics that are reviewed here attest to the continued growth of the fields of chemical car cinogenesis and mutagenesis, including their recent and fruitful union with viral oncology. I feel very optimistic about the application of knowledge in these fields to the eventual solution of numerous problems, including the detection and estimation of the risks to humans of environmental chemical carcinogens and re lated factors.

Author : Anonim
Publisher : Springer Science & Business Media
Page : 617 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642747755

Get Book

Chemical Carcinogenesis and Mutagenesis I by Anonim Pdf

I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin Madison. I immediately started to work with the carcinogenic aminoazo dyes un der the direction of Professor CARL BAUMANN. In 1942 I joined a fellow graduate student, ELIZABE1H CAVERT, in marriage and we soon commenced a joyous part nership in research on chemical carcinogenesis at the McArdle Laboratory for Cancer Research in the University of Wisconsin Medical School in Madison. This collaboration lasted 45 years. I am very grateful that this volume is dedi cated to the memory of Elizabeth. The important and varied topics that are reviewed here attest to the continued growth of the fields of chemical car cinogenesis and mutagenesis, including their recent and fruitful union with viral oncology. I feel very optimistic about the application of knowledge in these fields to the eventual solution of numerous problems, including the detection and estimation of the risks to humans of environmental chemical carcinogens and re lated factors.

Author : Colin S. Cooper,Philip L. Grover
Publisher : Springer Science & Business Media
Page : 482 pages
File Size : 48,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642747786

Get Book

Chemical Carcinogenesis and Mutagenesis II by Colin S. Cooper,Philip L. Grover Pdf

I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin Madison. I immediately started to work with the carcinogenic aminoazo dyes un der the direction of Professor CARL BAUMANN. In 1942 I joined a fellow graduate student, ELIZABETH CA VERT, in marriage and we soon commenced a joyous part nership in research on chemical carcinogenesis at the McArdle Laboratory for Cancer Research in the University of Wisconsin Medical School in Madison. This collaboration lasted 45 years. I am very grateful that this volume is dedi cated to the memory of Elizabeth. The important and varied topics that are reviewed here attest to the continued growth of the fields of chemical car cinogenesis and mutagenesis, including their recent and fruitful union with viral oncology. I feel very optimistic about the application of knowledge in these fields to the eventual solution of numerous problems, including the detection and estimation of the risks to humans of environmental chemical carcinogens and re lated factors.

Author : F. A. Beland,Colin S. Cooper,P. L. Grover
Publisher : Unknown
Page : 128 pages
File Size : 44,8 Mb
Release : 1990
Category : Electronic
ISBN : OCLC:834640090

Get Book

Chemical carcinogenesis and mutagenesis by F. A. Beland,Colin S. Cooper,P. L. Grover Pdf

Author : J. F. Douglas
Publisher : Springer Science & Business Media
Page : 339 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461251644

Get Book

Carcinogenesis and Mutagenesis Testing by J. F. Douglas Pdf

Cancer has become the most critical health problem in the United States. It is expected that 25% of the people will develop this dread disease, and many of these will die from the malady. The causes of cancer are varied, but the best estimate available is that 70--90% arise from environmental factors. These statistics have triggered widespread governmental action along two lines: (l) An effort to identify those chemicals and conditions that give rise to malignant processes has been mounted by the Carcino genesis Testing Program, the National Cancer Program, and subse quently, the National Toxicology Program. (2) Regulatory laws have been enacted that are administered by agencies such as TSCA, FIFRA, EPA, FDA, OSHA, and so on, whose mission is to minimize public ex posure to carcinogens. Since direct verification that specific chemicals induce cancer in hu of unanticipated expo mans is necessarily limited to known incidences sure and is therefore rare, most chemicals are identified as carcinogens only by laboratory experiments. At present, the only accepted procedure is long-term animal bioassay, and not only are these studies expensive and time-consuming, but current worldwide resources permit the evalua tion of only 300-400 chemicals per year, a miniscule amount compared to what is available in the commercial world: 30,000 existing chemicals, with approximately 700 new such materials being introduced every year.

Author : C. S. Cooper
Publisher : Unknown
Page : 467 pages
File Size : 49,7 Mb
Release : 1990
Category : Electronic
ISBN : OCLC:37010525

Get Book

Chemical Carcinogenesis and Mutagenesis Ii by C. S. Cooper Pdf

Author : Frederick A. Beland
Publisher : Unknown
Page : 0 pages
File Size : 55,7 Mb
Release : 1990
Category : Carcinogenesis
ISBN : 0387511830

Get Book

Chemical Carcinogenesis and Mutagenesis by Frederick A. Beland Pdf

Author : Beatrice Singer,D. Grunberger
Publisher : Springer Science & Business Media
Page : 352 pages
File Size : 50,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461337720

Get Book

Molecular Biology of Mutagens and Carcinogens by Beatrice Singer,D. Grunberger Pdf

This book originated in numerous Gordon Research Conferences and many other meetings of scientists working in chemistry, biophysics, biochemistry, and biology related to mutagenesis and carcinogenesis. It seemed the appro priate time to sit back and summarize the results of several decades of research in laboratories in different countries. We are very grateful to the Rockefeller Foundation for inviting us to formulate and begin writing the book at the Center for International Studies in Bellagio, Italy, where we were Resident Scholars. We are fortunate to have had the assistance of so many colleagues around the world who cheerfully sent original data, figures, and preprints and lis tened patiently to us as we worked out the various conflicting ideas in this fast-moving. field. The names of these scientists are found within the tables, figures, and references. There is one person whose contributions we especially wish to acknowl edge. Professor Heinz Fraenkel-Conrat was present at the inception of this book and throughout the writing encouraged and criticized in apprOximately equal proportion. Finally, his editing and amalgamation of our two styles gave us great comfort. B.S. D.G.

Author : Lawrence Fishbein
Publisher : Unknown
Page : 324 pages
File Size : 41,7 Mb
Release : 1977
Category : Carcinogens
ISBN : UCAL:C3090804

Get Book

Potential Industrial Carcinogens and Mutagens by Lawrence Fishbein Pdf

Author : Trevor M. Penning
Publisher : Springer Science & Business Media
Page : 447 pages
File Size : 54,6 Mb
Release : 2011-03-03
Category : Medical
ISBN : 9781617379956

Get Book

Chemical Carcinogenesis by Trevor M. Penning Pdf

This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.

Author : Anonim
Publisher : Springer
Page : 604 pages
File Size : 54,9 Mb
Release : 1989-11-27
Category : Medical
ISBN : 3540511822

Get Book

Chemical Carcinogenesis and Mutagenesis I by Anonim Pdf

I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin Madison. I immediately started to work with the carcinogenic aminoazo dyes un der the direction of Professor CARL BAUMANN. In 1942 I joined a fellow graduate student, ELIZABE1H CAVERT, in marriage and we soon commenced a joyous part nership in research on chemical carcinogenesis at the McArdle Laboratory for Cancer Research in the University of Wisconsin Medical School in Madison. This collaboration lasted 45 years. I am very grateful that this volume is dedi cated to the memory of Elizabeth. The important and varied topics that are reviewed here attest to the continued growth of the fields of chemical car cinogenesis and mutagenesis, including their recent and fruitful union with viral oncology. I feel very optimistic about the application of knowledge in these fields to the eventual solution of numerous problems, including the detection and estimation of the risks to humans of environmental chemical carcinogens and re lated factors.

Author : Ashis K. Basu, Takehiko Nohmi
Publisher : MDPI
Page : 275 pages
File Size : 44,6 Mb
Release : 2018-08-27
Category : Electronic
ISBN : 9783038971290

Get Book

Chemically-Induced DNA Damage, Mutagenesis, and Cancer by Ashis K. Basu, Takehiko Nohmi Pdf

This book is a printed edition of the Special Issue " Chemically-Induced DNA Damage, Mutagenesis, and Cancer" that was published in IJMS

Author : Philip L. Grover
Publisher : CRC Press
Page : 344 pages
File Size : 47,7 Mb
Release : 2019-06-04
Category : Medical
ISBN : 9780429536298

Get Book

Chemical Carcinogens & Dna by Philip L. Grover Pdf

First published in 1979, Chemical Carcinogenesis and DNA is an essential guide to the relationship between mutagens, carcinogens and our own genetic makeup. Covering a range of associated topics, this volume provides information that would prove most beneficial for practitioners of medicine and students alike.

Author : A. Kappas
Publisher : Springer Science & Business Media
Page : 276 pages
File Size : 42,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461538080

Get Book

Mechanisms of Environmental Mutagenesis-Carcinogenesis by A. Kappas Pdf

The 19th annual meeting of the European Environmental Mutagen Society was held in Rhodes, Greece, from October 21st to 26th, 1989. The programme was chosen to explore what is currently known about the mechanisms of mutagenesis and carcinogenesis, induced by environmental agents, and the questions regarding the relationship of these two processes. Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy. Researchers from allover the world contributed to the programme of the meeting with posters and oral presentations, providing a variety of new data and interesting scientific approaches. A number of outstanding scientists were invited to present the results of their work. It is only their presenta tions which are included in this book, covering the following topics: Mutations and carcinogenesis; mechanisms of chemical ly-induced genetic effects on molecular, chromosomal and cell division level; adaptability and repair mechanisms; chemical carcinogenesis and oncogenes; structure and metabolism of mutagens-carcinogens; biomonitoring and epidemiology of humans exposed to environmental mutagens-carcinogens. For the sake of evaluating and controlling the mutagenic and carcinogenic potential of our environment it is indispens able to understand the mechanisms and processes by which chemicals act on the genetic material, causing either heredi tary disease or cancer. The pUblication of these proceedings will hopefully contribute to this task.

Author : Frederick J. De Serr,A. Hollaender
Publisher : Springer Science & Business Media
Page : 495 pages
File Size : 52,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781461330721

Get Book

Chemical Mutagens by Frederick J. De Serr,A. Hollaender Pdf