Chemical Immunology

Author : Curtis A. Williams,Merrill W. Chase
Publisher : Academic Press
Page : 480 pages
File Size : 52,5 Mb
Release : 2014-05-12
Category : Medical
ISBN : 9781483222998

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Physical and Chemical Methods by Curtis A. Williams,Merrill W. Chase Pdf

Methods in Immunology: Volume II, Physical and Chemical Methods is a collection of papers dealing with electrophoresis, analytical ultracentrifugation, dialysis, ultrafiltration, cellulose ion exchangers, and chromatographic separation of macromolecules on porous gels. Some papers explain the applications of radioisotopes, optical analysis, and chemical analysis of proteins, carbohydrates, lipids, and nucleic acid. One paper describes the theory of electro-migration. Factors such as electrical charge or frictional coefficients govern the rate of migration of charged particles in an electric field. The differences found in their velocities can be used to separate substances or analyze them. Mobility is a characteristic property of molecules and can also be influenced by the composition of the medium or solution. Dialysis separates solvents too large to diffuse through a barrier from smaller solutes; ultrafiltration (reverse osmosis) forces solvent and solutes up to a certain critical size through the barrier by a high pressure on one side. The book notes that the membrane never becomes plugged in dialysis because of some opposite movement of the solvent. Another paper points out that the significance of radioactive tracers in immunochemistry employed to identify and label macromolecules functioning as antigens and antibodies. The collection can prove valuable to bio-chemists, cellular biologists, micro-biologists, developmental biologists, and scientists involved in immunological research.

Author : Udo R. Markert
Publisher : Karger Medical and Scientific Publishers
Page : 201 pages
File Size : 46,9 Mb
Release : 2005-01-01
Category : Medical
ISBN : 9783805579704

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Immunology of Pregnancy by Udo R. Markert Pdf

This book presents the discipline of immunology which studies a unique physiological phenomenon contradicting many of the generally established rules in the field: immunology of pregnancy. It provides a wide overview of the current research of this topic. Prominent and leading international groups contributed by reviewing the most significant findings in the field.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 44,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Kenneth B M Reid,Robert B Sim
Publisher : Royal Society of Chemistry
Page : 312 pages
File Size : 49,8 Mb
Release : 2008-09-29
Category : Medical
ISBN : 9781847558848

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Molecular Aspects of Innate and Adaptive Immunity by Kenneth B M Reid,Robert B Sim Pdf

The understanding, at the molecular level, of the interactions between innate and adaptive arms of the immune system is currently a hot topic, particularly to those interested in immunology - especially susceptibility to infectious diseases. This book provides a survey of topics, in the area of innate and adaptive immunity, which have been researched within the MRC Immunochemistry Unit, at Oxford University, over a period of forty years. The topics include: " antibody structure - for which the first Director of the Immunochemistry Unit, Professor RR Porter, was awarded a Nobel prize in 1972 " the characterization of membrane proteins on lymphoid cells - leading to the concept of these molecules belonging to an immunoglobulin super family " the proteins of the human serum complement system - one of the body's major defences against microbial infection " the human cell -surface integrins and the hyaluronan- binding proteins, which are involved in regulation of inflammation at cell surfaces and within the extracellular matrix " the family of collectin molecules - containing distinct globular carbohydrate -binding domains linked to collagen-like regions - which play important roles in innate immunity in the lungs and bloodstream by immediate recognition and clearance of microbial pathogens Each chapter in the book gives a brief historical background to a topic and then provides a survey of recent advances in the field and are written by internationally recognised renowned experts. The theme running through the chapters is that of protein structure-function relationships - including, amongst others, descriptions of quaternary structures of large oligomeric proteins, of Factor H and C1q binding to specific ligands, and of the chemistry of the mechanism of catalysis of covalent binding of activated C3 and C4 proteins to nucleophilic groups on microbial surfaces. In several chapters excellent descriptions are given with respect to how the immune system can be recruited to combat microbial infection - via proteins of both the innate and adaptive immune systems. The book also includes notable chapters which are excellent examples of the importance of how the isolation, characterisation, protein engineering and crystallisation has resulted in a full understanding of complex protein-protein interactions involved in the recognition and triggering events of important sections of the immune system: -Structure and Function of the C1 Complex - GÚrard J. Arlaud -Chemical Engineering of Therapeutic Antibodies - George T Stevenson -Leukocyte surface proteins - purification and characterisation - A. Neil Barclay -Cell Surface Integrins - Suet-Mien Tan and S.K. Alex Law This book is aimed primarily at established senior research scientists, postdoctoral research scientists and PhD students who have an interest in proteins of the immune system. However, the wide range of immunity system topics, while staying broadly within innate/adaptive immunity will also appeal to a wider audience.

Author : Matthew S. Macauley,Christoph Rademacher,Karina Valeria Mariño
Publisher : Frontiers Media SA
Page : 175 pages
File Size : 45,5 Mb
Release : 2020-07-17
Category : Electronic
ISBN : 9782889638666

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Addressing Roles for Glycans in Immunology using Chemical Biology by Matthew S. Macauley,Christoph Rademacher,Karina Valeria Mariño Pdf

Author : Curtis A. Williams
Publisher : Unknown
Page : 459 pages
File Size : 46,8 Mb
Release : 1968
Category : Immunochemistry
ISBN : OCLC:249091502

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Physical and Chemical Methods by Curtis A. Williams Pdf

Author : Anonim
Publisher : Unknown
Page : 282 pages
File Size : 41,5 Mb
Release : 2002
Category : Allergy
ISBN : IND:30000121635894

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Chemical Immunology by Anonim Pdf

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 42,7 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author : Curtis Alvin Williams,Merrill W. Chase
Publisher : Unknown
Page : 490 pages
File Size : 41,9 Mb
Release : 1968
Category : Immunity
ISBN : UOM:39015003387217

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Methods in Immunology and Immunochemistry: Physical and chemical methods by Curtis Alvin Williams,Merrill W. Chase Pdf

Author : Stanley Cohen
Publisher : Unknown
Page : 376 pages
File Size : 44,8 Mb
Release : 1986
Category : Immune response
ISBN : UCAL:B4514967

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Chemical Mediators of Inflammation and Immunity by Stanley Cohen Pdf

From the Preface: This volume deals with chemical and molecular aspects of inflammatory responses that may be induced by immunologic or nonimmunologic means. Certain purely immunologic factors such as Interleukin 2 are included because they can potentiate immune responses that have important inflammatory consequences...We have attempted to stress those mediators and those reactions that appear to play a critical role in tissue injury and repair, as well as protection against disease processes.

Author : Emanuela Corsini,Henk Van Loveren
Publisher : John Wiley & Sons
Page : 355 pages
File Size : 49,7 Mb
Release : 2014-08-06
Category : Science
ISBN : 9783527676996

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Molecular Immunotoxicology by Emanuela Corsini,Henk Van Loveren Pdf

The human immune system is constantly exposed to chemical contaminants, whether from food, water or air. Some chemicals directly elicit an immune response, while others indirectly activate or deactivate components within the immune system. Thus when tracking or predicting the effect of a chemical on the immune system, many different pathways and modes of action need to be considered. Following an introduction to the various pathways and toxicity mechanisms from a systemic perspective, the main part of this comprehensive reference surveys individual molecular mechanisms of important immunotoxicants, from PAHs to biopharmaceuticals, and from receptor-mediated toxicity to nanoparticle toxicity, using analyses based on molecular effects rather than on animal models. Taken together, the knowledge presented here provides an up-to-date overview of this hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.

Author : Elvin A. Kabat
Publisher : Elsevier
Page : 341 pages
File Size : 54,5 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483274263

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Blood Group Substances by Elvin A. Kabat Pdf

Blood Group Substances: Their Chemistry and Immunochemistry focuses on the characteristics, reactions, sources, and transformations of blood group substances. The book first offers information on human blood group factors and the methods and reagents used in testing for blood group antibodies and antigens. Topics include autoantibody formation and hemolytic anemia, panagglutinable erythrocytes, effects of temperature on hemagglutination, and effects of periodate on blood group substances. The text also ponders on the sources and purification of blood group substances. The publication examines the chemical and immunochemical characterization of blood group substances and immunochemical similarities and differences among blood group substances from various species. The text then takes a look at antibodies to blood group substances and their biological effects, including purification and concentration of blood group antibodies; studies with antibodies labeled with radioactive isotopes; and passage of antibodies through the placenta. The manuscript is a valuable reference for readers interested in blood group substances.

Author : Helen Tryphonas,Michel Fournier,Barry R. Blakley,Judit Smits,Pauline Brousseau
Publisher : CRC Press
Page : 788 pages
File Size : 44,9 Mb
Release : 2005-01-27
Category : Medical
ISBN : 9781134393992

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Investigative Immunotoxicology by Helen Tryphonas,Michel Fournier,Barry R. Blakley,Judit Smits,Pauline Brousseau Pdf

Investigative Immunotoxicology provides a critical evaluation of proposed experimental animal models and approaches, and discusses the contribution that immunotoxicity can make to the overall assessment of chemical-induced adverse health effects on humans and the ecosystem. Following a review of general concepts in immunotoxicology, the book discus

Author : Michael Potter,Noel Rose
Publisher : Springer Science & Business Media
Page : 423 pages
File Size : 45,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642852268

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Immunology of Silicones by Michael Potter,Noel Rose Pdf

This issue of Current Topics in Microbiology and Immunology records the proceedings of a Workshop on the Immunology of Sili cones held at the Natcher Conference Center, National Institutes of Health, Bethesda, Maryland, March 13 and 14, 1995. A large num ber of investigators from North America and Europe met to discuss available data on how the immune system responds to silicones and related materials. Some aspects of this field are controversial. Nonetheless, the meeting was marked by a civil and open ex change of scientific information and divergent interpretations, re flecting the traditions of scientific communication. Each invited participant was asked to submit an article sum marizing his/her presentation. Most of the papers are published as submitted, with only editorial changes to conform with the guide lines given to each contributor or revisions to clarify aspects of the paper. The papers should not be regarded as peer-reviewed publi cations. This preface will attempt to outline some of the immu nological areas of investigation relating to silicones.

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 40,7 Mb
Release : 1989
Category : Antigenic Determinants
ISBN : OCLC:22815105

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Antigenic Determinants and Immune Regulation by Anonim Pdf