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Author : Anonim
Publisher : Unknown
Page : 668 pages
File Size : 50,9 Mb
Release : 1976
Category : Kallikrein
ISBN : UCAL:B4988318
Author : Anonim
Publisher : Unknown
Page : 666 pages
File Size : 51,6 Mb
Release : 1976*
Category : Electronic
ISBN : STANFORD:24500194650
Author : John J. Pisano,Karl Frank Austen
Publisher : Unknown
Page : 612 pages
File Size : 49,7 Mb
Release : 1977
Category : Kallikrein
ISBN : OCLC:1051315683
Author : Anonim
Publisher : Unknown
Page : 612 pages
File Size : 44,8 Mb
Release : 1975
Category : Electronic
ISBN : OCLC:499485993
Author : Stephen G. Farmer
Publisher : Academic Press
Page : 371 pages
File Size : 55,9 Mb
Release : 1997-04-01
Category : Medical
ISBN : 9780080542522
Bradykinin is a type of plasma hormone that causes blood vessels to dilate, resulting in a drop in blood pressure, the contraction of muscles in the lungs, intestines, and uterus, and pain. The Kinin System reviews the molecular biology of the kinins through their roles in a complex array of inflammatory conditions such as asthma, GI disease, cardiovascular complaints and examines the future therapeutic opportunities. From the prepublication reviews:"A delicious masterpiece."--Chef's DigestThe Kinin System is a comprehensive, timely book covering all aspects of the kinin system from its disocvery to the pathophysiology, pharmacology, and molecular biology of the mechanisms regulating kinin production to kinin receptors in health and disease. The authors take a refreshingly different view of the kinin system than previous books on the subject. Several chapters contain new information on the gene expression, regulation, and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the role of kinins in pain angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinits, myocardial ischemia, and other diseases. * * Offers new information on kinin reception, regulation of gene expression of receptors, and kinin-generating proteins.* Provides a distinctly immunopharmacological approach to the kinin system.* Reviews of the role of kinins in disease and inlcudes data from human studies.* Includes information that is fully up-to-date and comprehensive.
Author : K. Abe
Publisher : Springer
Page : 692 pages
File Size : 44,7 Mb
Release : 1989-09-01
Category : Medical
ISBN : 0306432080
The physiological and pathological significance of the kallikrein-kinin system was recently explored extensively, resulting in a rapid accumulation of information regarding their potential importance. This publication provides an integrated picture of the latest information on the kallikrein kinin system. It contains contributions from morphologists, geneticists, biochemists, pharmacologists, physiologists, and clinicians. The Fifth International Kinin Congress (Nov. 29-Dec. 3, 1987) provided a forum for the exchange of information and ideas on the kallikrein-kinin system. The participation of more than 350 scientists from 23 countries reflects the widespread interest and international scope of research activity in the physiological and pathological functions of the kallikrein-kinin system. A total of 275 papers including posters were presented, attesting to the unquestioned success of this Congress. These proceedings, in two volumes, contain the collective studies presented, studies of high scientific standard that provoked stimulating and fruitful discussions. Also included in these volumes are the two plenary lectures presented by Dr. H.A. Margolius (USA) and Dr. S. Nakanishi (Japan). During the last decade our knowledge of the role of the kallikrein kinin system in health and disease has been greatly advanced by the develop ment of antagonists to bradykinin and the introduction to clinical practice of converting enzyme inhibitors. Symposia on converting enzyme and on recent advances in research on the kallikrein-kinin system are included in the proceedings.
Author : John J. Pisano,Karl Frank Austen
Publisher : Unknown
Page : 652 pages
File Size : 48,5 Mb
Release : 1977
Category : Kallikrein
ISBN : PURD:32754081178455
The diversity and significance of recent research on the kallikrein-kinin system provided the impetus for this international conference, the purpose of which was the assessment of our knowledge and the development of a base from which to plan future research. Through the generous support of the Fogarty International Center and of the National Heart, Lung, and Blood Institute, the Organizing Committee was able to bring together authorities in virtually every aspect of kinin research. The kallikrein-kinin field was divided into three major areas: A) Characterization and assays of components of the kallikrein-kinin systems; B) Interacting systems: Fibrinolysis, complement, coagulation, and prostaglandins; and C) Physiological, pathological, and clinical significance. Invited experts were instructed to present concise critical reviews along with any new data. Time was a)so provided for discussants to present relevant comments and data. Selected discussions accompany the keynote reports, and these comprise the short chapters.
Author : Alton Meister
Publisher : John Wiley & Sons
Page : 462 pages
File Size : 46,7 Mb
Release : 2009-09-15
Category : Science
ISBN : 9780470124437
Advances in Enzymology and Related Areas of Molecular Biology is a seminal series in the field of biochemistry, offering researchers access to authoritative reviews of the latest discoveries in all areas of enzymology and molecular biology. These landmark volumes date back to 1941, providing an unrivaled view of the historical development of enzymology. The series offers researchers the latest understanding of enzymes, their mechanisms, reactions and evolution, roles in complex biological process, and their application in both the laboratory and industry. Each volume in the series features contributions by leading pioneers and investigators in the field from around the world. All articles are carefully edited to ensure thoroughness, quality, and readability. With its wide range of topics and long historical pedigree, Advances in Enzymology and Related Areas of Molecular Biology can be used not only by students and researchers in molecular biology, biochemistry, and enzymology, but also by any scientist interested in the discovery of an enzyme, its properties, and its applications.
Author : Anonim
Publisher : Springer Science & Business Media
Page : 829 pages
File Size : 42,8 Mb
Release : 2013-11-27
Category : Medical
ISBN : 9783642673016
Volume XXV of the Handbook of Experimental Pharmacology series entitled "Bradykinin, Kallidin, and Kallikrein" was published in 1970. My aim in editing this volume of the series is not to replace, but to update the 1970 edition. During the decade preceding the publication of Vol. XXV, the existence of kinins and kallikreins gained acceptance, the protein components of the system were purified and characterized and the peptides were synthesized. Even after these accomplish ments, interest in the subject has not abated, but has increased substantially. We have learned a great deal about the role that components of the kallikrein-kinin system play in other systems and about the immensely complex and intricate inter actions in blood. Directly or indirectly, kallikrein and kinins affect the coagulation of blood, the activation of complement, and the generation of angiotensin. Kinins release or modulate the actions of other agents, including prostaglandins, histamine, and catecholamines. Inhibitors of kallikrein or kininase II are employed, for example, in extracorporeal circulation or in hypertension. Kallikrein, kinins, and kininases, present in urine, were described first in 1925 and 1954, but have been ignored for decades. These substances are now studied extensively because of their possible role in blood pressure regulation. The evidence that kinins have a metabolic function is also increasing. The abundance of active components of the system in genital organs suggests a role in the fertilization process. The book is organized into chapters which bear upon these issues.
Author : National Heart, Lung, and Blood Institute. Hypertension Task Force
Publisher : Unknown
Page : 196 pages
File Size : 51,5 Mb
Release : 1979
Category : Electronic
ISBN : UOM:39015062439362
Author : National Heart, Lung, and Blood Institute. Hypertension Task Force
Publisher : Unknown
Page : 196 pages
File Size : 48,9 Mb
Release : 1979
Category : Hypertension
ISBN : MINN:30000010684979
Abstract: The current state of hypertension research is reviewed, focusing on 12 special hypertension concerns and covering each concern with the following: an evaluation of the current literature, recommendations for future research, and a comprehensive list of references. Volume 1, written for the public, examines hypertension as both a public health and a research problem, and Volume 2, written for the biomedical community, explores general recommendations, and summaries of scientific reports are covered in volumes 3 through 9.
Author : Gert L. Haberland,Ulla Hamberg
Publisher : Elsevier
Page : 294 pages
File Size : 46,8 Mb
Release : 2016-06-06
Category : Medical
ISBN : 9781483159096
Current Concepts in Kinin Research contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held in Paris on July 22, 1978. The book is organized into four parts. Part I explains the functions and mechanisms of the kinin system. Part II focuses on kallikreins and the methods of their determination. Part III describes the intrinsic blood clotting and plasma kinin formation. The last part deals with the characterization of plasma kininogens.
Author : Rodger L. Bick
Publisher : Lippincott Williams & Wilkins
Page : 472 pages
File Size : 43,6 Mb
Release : 2002
Category : Medical
ISBN : 0397516908
Written for a multidisciplinary audience, this revision presents current data on antithrombotic therapy including warfarins and heparin, delivers practical techniques for diagnosing and treating bleeding and clotting disorders, and includes all topics necessary for board review. This practical text covers disorders of thrombosis and hemostasis in a logical and sequential manner: etiology, pathophysiology, clinical and laboratory diagnosis, and management. Also included are diagnostic tests for deep venous thrombosis, three new clotting defects, hereditary disorders and defects, liver and renal diseases, cardiovascular events, and problems in obstetrical/gynecological patients. A Brandon-Hill recommended title.
Author : Rodger L. Bick
Publisher : CRC Press
Page : 220 pages
File Size : 54,6 Mb
Release : 2019-06-04
Category : Medical
ISBN : 9780429557385
Published in 1983: This monograph represents a complete discussion of disseminated intravascular coagulation and related syndromes. Special interest if places upon relating DIC and associated syndromes to all areas of medical specialty where it is commonly seen.
Author : National Institutes of Health (U.S.)
Publisher : Unknown
Page : 364 pages
File Size : 50,7 Mb
Release : 1978
Category : Biochemistry
ISBN : UOM:39015082380273
Each issue lists papers published during the preceding year.