Chiral Analysis

Author : Kenneth W. Busch,Marianna A. Busch
Publisher : Elsevier
Page : 720 pages
File Size : 40,7 Mb
Release : 2011-10-13
Category : Science
ISBN : 0080469280

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Chiral Analysis by Kenneth W. Busch,Marianna A. Busch Pdf

Chiral Analysis covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals. The target audience is scientific professionals with an undergraduate background in chemistry or a related discipline, specifically organic chemists, researchers in drug discovery, pharmaceutical researchers involved with process analysis or combinatorial libraries, and graduate students in chemistry. Chapters have been written with the nonspecialist in mind so as to be self-contained. * Broad coverage - spectroscopic and separation methods covered in a single volume * Up-to-date and detailed review of the various techniques available and/or under development in this field * Contributions from leading experts in the field

Author : P.L. Polavarapu
Publisher : Elsevier
Page : 824 pages
File Size : 51,7 Mb
Release : 2018-05-30
Category : Science
ISBN : 9780444640284

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Chiral Analysis by P.L. Polavarapu Pdf

Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, Second Edition covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised second edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers. Another topic, chirality in extraterrestrial life, has not been discussed in any other book and is important for understanding the origin of life. Offers the only book to cover both spectroscopic and separation methods in a single volume Provides an up-to-date and detailed review of the various techniques available, including new techniques that have emerged since the first edition Includes contributions from a range of leading experts in the field, now edited by award-winning chirality researcher Prasad Polavarapu

Author : Teresa Kowalska,Joseph Sherma
Publisher : CRC Press
Page : 437 pages
File Size : 51,5 Mb
Release : 2007-06-22
Category : Medical
ISBN : 9780849343964

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Thin Layer Chromatography in Chiral Separations and Analysis by Teresa Kowalska,Joseph Sherma Pdf

Thin layer chromatography (TLC) is well suited for performing enantioseparations for research as well as larger-scale applications. A fast, inexpensive, and versatile separation technique, there are many practical considerations that contribute to its effectiveness. Thin Layer Chromatography in Chiral Separations and Analysis is the first bo

Author : Peter Schreier,Alexander Bernreuther,Manfred Huffer
Publisher : Walter de Gruyter
Page : 353 pages
File Size : 51,8 Mb
Release : 2011-06-01
Category : Science
ISBN : 9783110867855

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Analysis of Chiral Organic Molecules by Peter Schreier,Alexander Bernreuther,Manfred Huffer Pdf

Author : Thomas E. Beesley,Raymond P. W. Scott
Publisher : John Wiley & Sons
Page : 526 pages
File Size : 48,8 Mb
Release : 1999-01-26
Category : Science
ISBN : 0471974277

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Chiral Chromatography by Thomas E. Beesley,Raymond P. W. Scott Pdf

Eine Ergänzung anderer, in der Reihe Separation Sciences bereits erschienener Titel. Viel Theorie und zahlreiche Anwendungsbeispiele für die Praxis der chiralen HPLC- und GC-Trennung machen dieses top-aktuelle Buch zu einer unverzichtbaren Informationsquelle für jeden Neueinsteiger auf diesem Gebiet. (11/98)

Author : R. Kallenborn,H. Hühnerfuss
Publisher : Springer Science & Business Media
Page : 232 pages
File Size : 41,5 Mb
Release : 2001-01-18
Category : Science
ISBN : 3540664238

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Chiral Environmental Pollutants by R. Kallenborn,H. Hühnerfuss Pdf

This monograph contains a survey on the role of chirality in ecotoxicological processes. The focus is on environmental trace analysis. Areas such as toxicology, ecotoxicology, synthetic chemistry, biology, and physics are also covered in detail in order to explain the different properties of enantiomers in environmental samples. This monograph delivers a comprehensive survey for environmental trace analysts, analytical chemists, ecotoxicologists, food scientists and experienced lab workers.

Author : Imran Ali,Hassan Y. Aboul-Enein
Publisher : John Wiley & Sons
Page : 368 pages
File Size : 55,6 Mb
Release : 2005-07-15
Category : Science
ISBN : 9780470867815

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Chiral Pollutants by Imran Ali,Hassan Y. Aboul-Enein Pdf

Today, among the various chiral discrimination methods, chromatography and capillary electrophoresis techniques have become powerful tools in environmental analysis. Therefore, there is a need to describe the art of the determination of the chiral pollutants in the environmental matrices. This book provides the complete information on the types of the chiral pollutants, their toxicities and methods of determination by chromatography and capillary electrophoresis.

Author : Bezhan Chankvetadze
Publisher : John Wiley & Sons
Page : 586 pages
File Size : 48,9 Mb
Release : 1997-12-29
Category : Science
ISBN : 0471974153

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Capillary Electrophoresis in Chiral Analysis by Bezhan Chankvetadze Pdf

Das weltweite Interesse an der Trennung von Enantiomeren, Spiegelbildern ein und derselben chemischen Verbindung, nimmt zu, da diese Formen beispielsweise verschiedene physiologische Wirkungen hervorrufen können. Eine hochaktuelle Technik der Stofftrennung in diesem Zusammenhang ist die Kapillarelektrophorese, die hier von den theoretischen Grundlagen bis hin zu analytischen Details und Anbieterlisten ausführlich beschrieben wird.

Author : Teresa Kowalska,Joseph Sherma
Publisher : CRC Press
Page : 436 pages
File Size : 43,5 Mb
Release : 2007-06-22
Category : Medical
ISBN : 9781000654318

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Thin Layer Chromatography in Chiral Separations and Analysis by Teresa Kowalska,Joseph Sherma Pdf

Thin layer chromatography (TLC) is well suited for performing enantioseparations for research as well as larger-scale applications. A fast, inexpensive, and versatile separation technique, there are many practical considerations that contribute to its effectiveness. Thin Layer Chromatography in Chiral Separations and Analysis is the first bo

Author : G. Subramanian
Publisher : Wiley-VCH
Page : 376 pages
File Size : 40,6 Mb
Release : 2001
Category : Science
ISBN : UOM:39015053518059

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Chiral Separation Techniques by G. Subramanian Pdf

This is a completely revised and updated sequel to 'A Practical Approach to Chiral Separations by Liquid Chromatography' by the same editor. The scope has been extended to further chiral separation techniques like electrophoresis, membrane separations, or biological assays. More emphasis is put on preparative separation techniques. From reviews of the previous edition: 'A team of experts from academic and industrial laboratories throughout the world have compiled their findings and experience to make this book an exceptionally timely and unique contribution to the field' European Journal of Drug Metabolism 'The dense mass of information contained in this book will make it a valuable resource ...' Chemical Engineering Research '... this is a worthwhile addition to the expanding chiral literature and the book should be of value to those working in this field' The Analyst

Author : Peter Mikuš
Publisher : BoD – Books on Demand
Page : 211 pages
File Size : 44,5 Mb
Release : 2012-08-29
Category : Medical
ISBN : 9789535106579

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Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis by Peter Mikuš Pdf

The scientific monograph by the author Peter Mikus entitled "Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis" provides a comprehensive view on the advanced capillary electrophoresis techniques aimed to current chiral bioanalysis. The advances in the chiral electrophoresis analytical approaches are divided and theoretically described in three sections involving (i) advanced chiral separations for the optimization of chiral resolution (separation mechanisms; electrophoresis techniques in capillary and microchip format; electrophoretic modes such as ITP, CZE/EKC, CEC; chiral additives / pseudophases / phases), (ii) advanced sample preparation for the on-line preconcentration, sample clean-up and analyte derivatization (implementation of electrophoretic effects such as stacking; non-electrophoretic effects such as SPE, chromatography, dialysis; combinations of these effects; multidimensional CE systems; instrumental schemes), (iii) advanced combinations of detection and electrophoresis for the optimization in qualitative and quantitative evaluation (the most important universal as well as selective detection approaches such as absorption and fluorescence spectrophotometry, electrochemical detection, mass spectrometry vs. (i) and/or (ii)). Real analytical potential (benefits and limitations) of these advanced analytical approaches is emphasized by selected performance parameters of the methods and illustrated by many current practical applications including chiral analyses of drugs, their (bio)degradation products and biomarkers in pharmaceutical and biological matrices. The author wishes the readers many inspirations in the creation of new innovative approaches in the field of advanced chiral electrophoresis techniques with the aim to overcome capabilities of the current analytical techniques.

Author : Satinder Ahuja
Publisher : John Wiley & Sons
Page : 474 pages
File Size : 51,5 Mb
Release : 2011-03-31
Category : Science
ISBN : 9781118097755

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Chiral Separation Methods for Pharmaceutical and Biotechnological Products by Satinder Ahuja Pdf

Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.

Author : Alain Berthod
Publisher : Springer Science & Business Media
Page : 337 pages
File Size : 52,6 Mb
Release : 2010-06-16
Category : Science
ISBN : 9783642124457

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Chiral Recognition in Separation Methods by Alain Berthod Pdf

What drives a scientist to edit a book on a speci c scienti c subject such as chiral mechanisms in separation methods? Until December 2005, the journal Analytical Chemistry of the American Chemical Society (Washington, DC) had an A-page section that was dedicated to simple and clear presentations of the most recent te- niques or the state of the art in a particular eld or topic. The “A-page” section was prepared for a broad audience of chemists including industrial professionals, s- dents as well as academics looking for information outside their eld of expertise. 1 Daniel W. Armstrong, one of the editors of this journal and a twenty-year+ long friend, invited me to present my view on chiral recognition mechanisms in a simple and clear way in an “A-page” article. In 2006, the “A-page” section was maintained as the rst articles at the beginning of each rst bi-monthly issue but the pagination was no longer page distinguished from the regular research articles published by the journal. During the time between the invitation and the submission, the A-page section was integrated into the rest of the journal and the article appeared as (2006) Anal Chem (78):2093–2099.

Author : Maria Elizabeth Tiritan,Madalena Pinto ,Carla Sofia Garcia Fernandes
Publisher : MDPI
Page : 346 pages
File Size : 50,9 Mb
Release : 2020-11-13
Category : Technology & Engineering
ISBN : 9783039362387

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Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition by Maria Elizabeth Tiritan,Madalena Pinto ,Carla Sofia Garcia Fernandes Pdf

This book includes both fundamental studies and applications in a multidisciplinary research field involving a high diversity of chiral compounds, including commercial substances with industrial applications, pharmaceuticals, and new chiral compounds with promising biological activities.

Author : Ganapathy Subramanian
Publisher : John Wiley & Sons
Page : 641 pages
File Size : 41,9 Mb
Release : 2008-01-08
Category : Science
ISBN : 9783527611720

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Chiral Separation Techniques by Ganapathy Subramanian Pdf

Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.