Collective Behavior In Systems Biology

Author : Assaf Steinschneider
Publisher : Academic Press
Page : 260 pages
File Size : 44,8 Mb
Release : 2019-09-04
Category : Science
ISBN : 9780128173374

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Collective Behavior In Systems Biology by Assaf Steinschneider Pdf

Collective Behavior In Systems Biology: A Primer on Modeling Infrastructure offers a survey of established and emerging methods for quantifying process behavior in cellular systems. It introduces and applies mathematics and related abstract methods to processes in biological systems - why they are used, how they work, and what they mean. Emphasizing differential equations in an interdisciplinary approach, this book discusses infrastructure for kinetic modeling, technological system and control theories, optimization, and process behavior in cellular networks. The knowledge that the reader gains will be valuable for entering and keeping up with a rapidly developing discipline. Introduces basics of mathematical and abstract methods for understanding, predicting, and modifying collective behavior in cellular systems Targets biomedical professionals as well as computational specialists who are willing to take advantage of novel high-throughput data acquisition technologies

Author : Deborah M. Gordon
Publisher : Princeton University Press
Page : 184 pages
File Size : 50,9 Mb
Release : 2023-10-24
Category : Science
ISBN : 9780691232157

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The Ecology of Collective Behavior by Deborah M. Gordon Pdf

A groundbreaking new perspective on collective behavior across biological systems Collective behavior is everywhere in nature, from gene transcription and cancer cells to ant colonies and human societies. It operates without central control, using local interactions among participants to allow groups to adjust to changing conditions. The Ecology of Collective Behavior brings together ideas from evolutionary biology, network science, and dynamical systems to present an ecological approach to understanding how the interactions of individuals generate collective outcomes. Deborah Gordon argues that the starting point for explaining how collective behavior works in any natural system is to consider how it changes in relation to the changing world around it. She shows how feedback use—the means by which networks of interactions operate—and the organization of interaction networks evolve to reflect the stability and demands of the environment. Ant colonies function collectively, and the enormous diversity of species in different habitats provides opportunities to look for general ecological patterns. Through an in-depth comparison of ant species, Gordon identifies broad trends in how the diversity of collective behavior in many other collective systems reflects the dynamics of the environment. Shedding light on how individual actions give rise to group behavior, The Ecology of Collective Behavior explains the evolution of collective behavior through innovation in participant interactions, offering new insights into how collective responses function in changing conditions.

Author : The National Academies Keck Futures Initiative
Publisher : National Academies Press
Page : 142 pages
File Size : 48,7 Mb
Release : 2015-06-25
Category : Science
ISBN : 9780309373500

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Collective Behavior by The National Academies Keck Futures Initiative Pdf

Collective Behavior is the summary of the 2014 National Academies Keck Futures Initiative Conference on Collective Behavior. Participants were divided into fourteen interdisciplinary research teams. The teams spent nine hours over two days exploring diverse challenges at the interface of science, engineering, and medicine. The composition of the teams was intentionally diverse, to encourage the generation of new approaches by combining a range of different types of contributions. The teams included researchers from science, engineering, and medicine, as well as representatives from private and public funding agencies, universities, businesses, journals, and the science media. Researchers represented a wide range of experience - from postdoc to those well established in their careers - from a variety of disciplines that included science and engineering, medicine, physics, biology, economics, and behavioral science. The teams needed to address the challenge of communicating and working together from a diversity of expertise and perspectives as they attempted to solve a complicated, interdisciplinary problem in a relatively short time. This report highlights the presentations of the event and includes the team reports and pre-meeting materials.

Author : Alessandro Abate,Tatjana Petrov,Verena Wolf
Publisher : Springer Nature
Page : 387 pages
File Size : 46,8 Mb
Release : 2020-10-01
Category : Computers
ISBN : 9783030603274

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Computational Methods in Systems Biology by Alessandro Abate,Tatjana Petrov,Verena Wolf Pdf

This book constitutes the refereed proceedings of the 18th International Conference on Computational Methods in Systems Biology, CMSB 2020, held in Konstanz, Germany, in September 2020.* The 17 full papers and 5 tool papers were carefully reviewed and selected from 30 submissions. In addition 3 abstracts of invited talks and 2 tutorials have been included in this volume. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; computational approaches for synthetic biology; and case studies in systems and synthetic biology. * The conference was held virtually due to the COVID-19 pandemic.

Author : Deborah M. Gordon
Publisher : Princeton University Press
Page : 184 pages
File Size : 54,5 Mb
Release : 2023-10-24
Category : Science
ISBN : 9780691232140

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The Ecology of Collective Behavior by Deborah M. Gordon Pdf

A groundbreaking new perspective on collective behavior across biological systems Collective behavior is everywhere in nature, from gene transcription and cancer cells to ant colonies and human societies. It operates without central control, using local interactions among participants to allow groups to adjust to changing conditions. The Ecology of Collective Behavior brings together ideas from evolutionary biology, network science, and dynamical systems to present an ecological approach to understanding how the interactions of individuals generate collective outcomes. Deborah Gordon argues that the starting point for explaining how collective behavior works in any natural system is to consider how it changes in relation to the changing world around it. She shows how feedback use—the means by which networks of interactions operate—and the organization of interaction networks evolve to reflect the stability and demands of the environment. Ant colonies function collectively, and the enormous diversity of species in different habitats provides opportunities to look for general ecological patterns. Through an in-depth comparison of ant species, Gordon identifies broad trends in how the diversity of collective behavior in many other collective systems reflects the dynamics of the environment. Shedding light on how individual actions give rise to group behavior, The Ecology of Collective Behavior explains the evolution of collective behavior through innovation in participant interactions, offering new insights into how collective responses function in changing conditions.

Author : Anonim
Publisher : Editora E-papers
Page : 455 pages
File Size : 50,5 Mb
Release : 2024-06-03
Category : Electronic
ISBN : 9788587922885

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Proc. of the Third Brazilian Symp. on Mathematical and Computational Biology - v1 by Anonim Pdf

Author : Sanket Joshi
Publisher : Springer Nature
Page : 587 pages
File Size : 49,8 Mb
Release : 2024-06-03
Category : Electronic
ISBN : 9789819994625

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Systems Biology Approaches: Prevention, Diagnosis, and Understanding Mechanisms of Complex Diseases by Sanket Joshi Pdf

Author : Vikram Singh,Pawan K. Dhar
Publisher : Springer
Page : 385 pages
File Size : 43,6 Mb
Release : 2014-12-15
Category : Science
ISBN : 9789401795142

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Systems and Synthetic Biology by Vikram Singh,Pawan K. Dhar Pdf

This textbook has been conceptualized to provide a detailed description of the various aspects of Systems and Synthetic Biology, keeping the requirements of M.Sc. and Ph.D. students in mind. Also, it is hoped that this book will mentor young scientists who are willing to contribute to this area but do not know from where to begin. The book has been divided into two sections. The first section will deal with systems biology – in terms of the foundational understanding, highlighting issues in biological complexity, methods of analysis and various aspects of modelling. The second section deals with the engineering concepts, design strategies of the biological systems ranging from simple DNA/RNA fragments, switches and oscillators, molecular pathways to a complete synthetic cell will be described. Finally, the book will offer expert opinions in legal, safety, security and social issues to present a well-balanced information both for students and scientists.

Author : Fabricio Alves Barbosa da Silva,Nicolas Carels,Floriano Paes Silva Junior
Publisher : Springer
Page : 259 pages
File Size : 44,5 Mb
Release : 2018-06-21
Category : Computers
ISBN : 9783319749747

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Theoretical and Applied Aspects of Systems Biology by Fabricio Alves Barbosa da Silva,Nicolas Carels,Floriano Paes Silva Junior Pdf

This book presents the theoretical foundations of Systems Biology, as well as its application in studies on human hosts, pathogens and associated diseases. This book presents several chapters written by renowned experts in the field. Some topics discussed in depth in this book include: computational modeling of multiresistant bacteria, systems biology of cancer, systems immunology, networks in systems biology.

Author : Daskalaki, Andriani
Publisher : IGI Global
Page : 982 pages
File Size : 42,5 Mb
Release : 2008-11-30
Category : Technology & Engineering
ISBN : 9781605660776

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Handbook of Research on Systems Biology Applications in Medicine by Daskalaki, Andriani Pdf

"This book highlights the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatics, molecular, and biochemical, to address fundamental questions in complex diseases like cancer diabetes but also in ageing"--Provided by publisher.

Author : Miguel A. Aon,Valdur Saks,Uwe Schlattner
Publisher : Springer Science & Business Media
Page : 375 pages
File Size : 43,7 Mb
Release : 2013-10-22
Category : Science
ISBN : 9783642385056

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Systems Biology of Metabolic and Signaling Networks by Miguel A. Aon,Valdur Saks,Uwe Schlattner Pdf

Systems Biology represents a new paradigm aiming at a whole-organism-level understanding of biological phenomena, emphasizing interconnections and functional interrelationships rather than component parts. The study of network properties, and how they control and regulate behavior from the cellular to organism level, constitutes a main focus of Systems Biology. This book addresses from a novel perspective a major unsolved biological problem: understanding how a cell works and what goes wrong in pathology. The task undertaken by the authors is in equal parts conceptual and methodological, integrative and analytical, experimental and theoretical, qualitative and quantitative, didactic and comprehensive. Essentially, they unravel the spatio-temporal unfolding of interacting mass-energy and information networks at the cellular and organ levels, as well as its modulation through activation or repression by signaling networks to produce a certain phenotype or (patho)physiological response. Starting with the historical roots, in thirteen chapters this work explores the Systems Biology of signaling networks, cellular structures and fluxes, organ and microorganism functions. In doing so, it establishes the basis of a 21st century approach to biological complexity.

Author : Robert A. Meyers
Publisher : John Wiley & Sons
Page : 729 pages
File Size : 45,8 Mb
Release : 2012-12-05
Category : Science
ISBN : 9783527668595

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Systems Biology by Robert A. Meyers Pdf

Systems biology is a relatively new biological study field that focuses on the systematic study of complex interactions in biological systems, thus using a new perspective (integration instead of reduction) to study them. Particularly from year 2000 onwards, the term is used widely in the biosciences, and in a variety of contexts. Systems biology is the study of the interconnected aspect of molecular, cellular, tissue, whole animal and ecological processes, and comprises mathematical and mechanistic studies of dynamical, mesoscopic, open, spatiotemporally defined, nonlinear, complex systems that are far from thermodynamic equilibrium.

Author : Alberto Marin-Sanguino,Julio Vera,Rui Alves
Publisher : Frontiers Media SA
Page : 216 pages
File Size : 55,5 Mb
Release : 2019-01-11
Category : Electronic
ISBN : 9782889456833

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Foundations of Theoretical Approaches in Systems Biology by Alberto Marin-Sanguino,Julio Vera,Rui Alves Pdf

If biology in the 20th century was characterized by an explosion of new technologies and experimental methods, that of the 21st has seen an equally exuberant proliferation of mathematical and computational methods that attempt to systematize and explain the abundance of available data. As we live through the consolidation of a new paradigm where experimental data goes hand in hand with computational analysis, we contemplate the challenge of fusing these two aspects of the new biology into a consistent theoretical framework. Whether systems biology will survive as a field or be washed away by the tides of future fads will ultimately depend on its success to achieve this type of synthesis. The famous quote attributed to Kurt Lewin comes to mind: "there is nothing more practical than a good theory". This book presents a wide assortment of articles on systems biology in an attempt to capture the variety of current methods in systems biology and show how they can help to find answers to the challenges of modern biology.

Author : Mariano Vázquez,Peter V. Coveney,Hernan Edgardo Grecco,Alfons Hoekstra,Bastien Chopard
Publisher : Frontiers Media SA
Page : 449 pages
File Size : 49,8 Mb
Release : 2019-04-04
Category : Electronic
ISBN : 9782889458172

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Advanced HPC-based Computational Modeling in Biomechanics and Systems Biology by Mariano Vázquez,Peter V. Coveney,Hernan Edgardo Grecco,Alfons Hoekstra,Bastien Chopard Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Nikolaus Rajewsky,Stefan Jurga,Jan Barciszewski
Publisher : Springer
Page : 401 pages
File Size : 42,5 Mb
Release : 2018-08-29
Category : Science
ISBN : 9783319929675

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Systems Biology by Nikolaus Rajewsky,Stefan Jurga,Jan Barciszewski Pdf

Many breakthroughs in experimental devices, advanced software, as well as analytical methods for systems biology development have helped shape the way we study DNA, RNA and proteins, on the genomic, transcriptional, translational and posttranslational level. This book highlights the comprehensive topics that encompass systems biology with enormous progress in the development of genome sequencing, proteomic and metabolomic methods in designing and understanding biological systems. Topics covered in this book include fundamentals of modelling networks, circuits and pathways, spatial and multi cellular systems, image-driven systems biology, evolution, noise and decision-making in single cells, systems biology of disease and immunology, and personalized medicine. Special attention is paid to epigenomics, in particular environmental conditions that impact genetic background. The breadth of exciting new data towards discovering fundamental principles and direct application of epigenetics in agriculture is also described. The chapter “Deciphering the Universe of RNA Structures and Trans RNA-RNA Interactions of Transcriptomes in vivo - from Experimental Protocols to Computational Analyses” is available open access under a CC BY 4.0 license via link.springer.com.