Combating Fungal Infections

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Combating Fungal Infections

Iqbal Ahmad,Mohammad Owais,Mohammed Shahid,Farrukh Aqil
Combating Fungal Infections Book PDF

Author : Iqbal Ahmad,Mohammad Owais,Mohammed Shahid,Farrukh Aqil
Publisher : Springer Science & Business Media
Page : 549 pages
File Size : 42,6 Mb
Release : 2010-08-03
Category : Medical
ISBN : 9783642121739

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Combating Fungal Infections by Iqbal Ahmad,Mohammad Owais,Mohammed Shahid,Farrukh Aqil Pdf

Fungi are eukaryotic microorganisms that are closely related to humans at cellular level. Human fungal pathogens belong to various classes of fungi, mainly zygo- cetes, ascomycetes, basidiomycetes, and deuteromycetes. In recent years, fungal infections have dramatically increased as a result of improved diagnosis, high frequency of catheterization, instrumentation, etc. However, the main cause remains the increasing number of immunosuppressed patients, mostly because of HIV infection and indiscriminate usage of antineoplastic and immunosuppressive agents, broad-spectrum antibiotics and prosthetic devices, and grafts in clinical settings. Presently available means of combating fungal infections are still weak and clumsy compared to control of bacterial infection. The present scenario of antifungal therapy is still based on two classes of antifungal drugs (polyenes and azoles). These drugs are effective in many cases, but display toxicity and limited spectrum of ef?cacy. The recent trend towards emergence of drug-resistant isolates in the clinic is an additional problem. In recent years, a few new antifungal drugs have entered the clinics, but they are expected to undergo same fate as the older antifungal drugs. The application of fungal genomics offers an unparalleled opportunity to develop novel antifungal drugs. However, it is too early to expect any novel drugs, as the antifungal drug discovery program is in the stage of infancy. Interestingly, several novel antifungal drug targets have been identi?ed and validated.

Antifungal Therapy

Mahmoud Ghannoum,John R. Perfect
Antifungal Therapy Book PDF

Author : Mahmoud Ghannoum,John R. Perfect
Publisher : CRC Press
Page : 484 pages
File Size : 43,6 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9780849387869

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Antifungal Therapy by Mahmoud Ghannoum,John R. Perfect Pdf

A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a c

Pocket Guide to Fungal Infection

Malcolm D. Richardson,Elizabeth M. Johnson
Pocket Guide to Fungal Infection Book PDF

Author : Malcolm D. Richardson,Elizabeth M. Johnson
Publisher : John Wiley & Sons
Page : 192 pages
File Size : 52,8 Mb
Release : 2008-05-12
Category : Medical
ISBN : 9781405173117

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Pocket Guide to Fungal Infection by Malcolm D. Richardson,Elizabeth M. Johnson Pdf

The Pocket Guide to Fungal Infection presents, in a convenient and practical format, the major features of fungal infections in humans, providing visual information for each pathogen and the infections they cause. The second edition has been extensively revised. In each chapter the clinical manifestations and management sections have been revised and updated to include recently developed antifungal drugs. New sections include; Emerging yeast and filamentous fungal pathogens Antifungal susceptibility testing Antifungal assays Molecular methods in medical mycology Mycological aspects of the indoor environment. Medical Mycology lends itself to illustration and as such there are over 40 additional images in this edition. Recent references have been added and the list of online resources has been updated. This Guide presents a succinct account of the clinical manifestations, laboratory diagnosis and management of fungal infections world-wide. It is an ideal publication for those who encounter fungal infections as part of their everyday practice, including medical microbiologists, infectious disease specialists, dermatologists and general practitioners.

Vulvovaginal Candidosis

Werner Mendling
Vulvovaginal Candidosis Book PDF

Author : Werner Mendling
Publisher : Springer Science & Business Media
Page : 179 pages
File Size : 49,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642833120

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Vulvovaginal Candidosis by Werner Mendling Pdf

Fungal infections in the female play an increasingly large role in everyday gynecological practice. This is the first book to deal comprehensively with vulvovaginal candidosis. Following an introduction outlining the incidence of yeasts in man, genital colonization in the female sex, yeast in pregnancy and neonatal mycoses, there is a description of the modes of infection and the known host reactions, as well as of the symptoms for diagnosis and therapy. Some 150 color illustrations depict all known facultative pathogenetic candida species and other potentially pathogenetic yeasts in pure culture and under the microscope. Clinical examples help explain the diagnosis and differential diagnosis. The volume provides the physician with handy, concise and practice-oriented guidelines to correct diagnosis and effective treatment of yeasts in the female patient.

Immunology of Fungal Infections

Gordon D. Brown,Mihai G. Netea
Immunology of Fungal Infections Book PDF

Author : Gordon D. Brown,Mihai G. Netea
Publisher : Springer
Page : 492 pages
File Size : 48,6 Mb
Release : 2009-09-03
Category : Medical
ISBN : 9048111307

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Immunology of Fungal Infections by Gordon D. Brown,Mihai G. Netea Pdf

This text covers all aspects of the immunology of fungal infection. Beyond the basics, coverage includes recent developments in innate and adaptive immunological mechanisms involved in the host response to fungal infection. The volume’s topical sections provide an immunological perspective on the cells, soluble factors and receptors involved in recognising and combating fungal infections. Discussion includes descriptions of immunity to specific pathogens, immune-escape mechanisms used by fungi, and therapeutic strategies.

Diagnosis and Treatment of Fungal Infections

Duane R. Hospenthal,Michael G. Rinaldi,Thomas J. Walsh
Diagnosis and Treatment of Fungal Infections Book PDF

Author : Duane R. Hospenthal,Michael G. Rinaldi,Thomas J. Walsh
Publisher : Springer Nature
Page : 426 pages
File Size : 41,6 Mb
Release : 2023-09-14
Category : Medical
ISBN : 9783031358036

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Diagnosis and Treatment of Fungal Infections by Duane R. Hospenthal,Michael G. Rinaldi,Thomas J. Walsh Pdf

Diagnosis and Treatment of Fungal Infections, 3rd Edition contains the latest research and clinical evidence on fungal infections in humans. Updated again by globally recognized experts, this concise text is divided into sections dedicated to the patient approach, laboratory and radiological diagnosis, systemic antifungal agents, mycoses, and instructive cases. It is a concise but comprehensive resource for use in conjunction with patient care duties and in teaching. It is the perfect guide for hospital-based primary care physicians, oncologists, critical care specialists, and infectious disease fellows with limited training or experience in the identification and management of fungal infections.

Recent Trends in Antifungal Agents and Antifungal Therapy

Amit Basak,Ranadhir Chakraborty,Santi M. Mandal
Recent Trends in Antifungal Agents and Antifungal Therapy Book PDF

Author : Amit Basak,Ranadhir Chakraborty,Santi M. Mandal
Publisher : Springer
Page : 250 pages
File Size : 41,5 Mb
Release : 2016-09-21
Category : Science
ISBN : 9788132227823

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Recent Trends in Antifungal Agents and Antifungal Therapy by Amit Basak,Ranadhir Chakraborty,Santi M. Mandal Pdf

Fungal infections have taken a new spectrum due to the increased incidence of multi-drug resistant fungal pathogens. Freedom of choice for drugs to treat fungal infections is also narrow because of lesser probability of discovering drugs that would bypass affecting human cells and target fungal cells producing fewer side effects in patients. An approach has gained prominence in research is to look for bioactive antifungal compounds from natural to synthetic sources. It is necessary to discover new classes of antifungals to control the recent emergence of multi-drug resistant fungal infections. This book proposed a details top to bottom outline of antifungal compounds derived naturally or synthetically. The details of their modifications or synthetic analogues have been described, helpful to understand the structure-activity relationship which leads to new compound development in antifungal chemotherapy. Each chapter begins with a comprehensive, top-bottom in-depth discussion of antifungal agents with updated bibliographic references. This compendium will serve as a companion not only for Scientists, Researchers, and Professors, Medical Practitioners but also a valuable reference text for the university students.

Antifungal Drug Discovery: New Theories and New Therapies

Anonim
Antifungal Drug Discovery New Theories and New Therapies Book PDF

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 53,9 Mb
Release : 2016
Category : Electronic
ISBN : OCLC:1368432798

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Antifungal Drug Discovery: New Theories and New Therapies by Anonim Pdf

Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the cells. Therefore, only a handful of antifungal agents are currently available to treat the myriad of fungal infections. Moreover, rising antifungal resistance and host-related adverse reactions have limited the antifungal arsenal against fungal pathogens. In this research topic, we tried to update the theoretical aspects pertaining to the antifungal drug discovery i.e. proposed novel mechanisms, new drug targets and pathways. In addition, invited authors explored the new antifungal drugs derived from natural and synthetic sources which are currently under development. Contributors were encouraged to bring new insight into the antifungal drug discovery. We hope the reader may arrive at a general consensus on the possible strategies to combat ever increasing ubiquitous fungal infection in this new century.

Antifungal Drug Discovery: New Theories and New Therapies

Chaminda Jayampath Seneviratne,Edvaldo Antonio Ribeiro Rosa
Antifungal Drug Discovery New Theories and New Therapies Book PDF

Author : Chaminda Jayampath Seneviratne,Edvaldo Antonio Ribeiro Rosa
Publisher : Frontiers Media SA
Page : 138 pages
File Size : 40,8 Mb
Release : 2016-09-13
Category : Microbiology
ISBN : 9782889199501

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Antifungal Drug Discovery: New Theories and New Therapies by Chaminda Jayampath Seneviratne,Edvaldo Antonio Ribeiro Rosa Pdf

Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the cells. Therefore, only a handful of antifungal agents are currently available to treat the myriad of fungal infections. Moreover, rising antifungal resistance and host-related adverse reactions have limited the antifungal arsenal against fungal pathogens. In this research topic, we tried to update the theoretical aspects pertaining to the antifungal drug discovery i.e. proposed novel mechanisms, new drug targets and pathways. In addition, invited authors explored the new antifungal drugs derived from natural and synthetic sources which are currently under development. Contributors were encouraged to bring new insight into the antifungal drug discovery. We hope the reader may arrive at a general consensus on the possible strategies to combat ever increasing ubiquitous fungal infection in this new century.

The EBMT Handbook

Nicolaus Kröger,Mohamad Mohty,Carlo Dufour
The EBMT Handbook Book PDF

Author : Nicolaus Kröger,Mohamad Mohty,Carlo Dufour
Publisher : Unknown
Page : 688 pages
File Size : 47,9 Mb
Release : 2020-10-08
Category : Medical
ISBN : 1013273672

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The EBMT Handbook by Nicolaus Kröger,Mohamad Mohty,Carlo Dufour Pdf

This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Oxford Textbook of Medical Mycology

Christopher C. Kibbler,Richard Barton,Neil A. R. Gow,Susan Howell,Donna M. MacCallum,Rohini J. Manuel
Oxford Textbook of Medical Mycology Book PDF

Author : Christopher C. Kibbler,Richard Barton,Neil A. R. Gow,Susan Howell,Donna M. MacCallum,Rohini J. Manuel
Publisher : Oxford University Press
Page : 401 pages
File Size : 47,5 Mb
Release : 2017-12-14
Category : Medical
ISBN : 9780198755388

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Oxford Textbook of Medical Mycology by Christopher C. Kibbler,Richard Barton,Neil A. R. Gow,Susan Howell,Donna M. MacCallum,Rohini J. Manuel Pdf

The Oxford Textbook of Medical Mycology is a comprehensive reference text which brings together the science and medicine of human fungal disease. Written by a leading group of international authors to bring a global expertise, it is divided into sections that deal with the principles of mycology, the organisms, a systems based approach to management, fungal disease in specific patient groups, diagnosis, and treatment. The detailed clinical chapters take account of recent international guidelines on the management of fungal disease. With chapters covering recent developments in taxonomy, fungal genetics and other 'omics', epidemiology, pathogenesis, and immunology, this textbook is well suited to aid both scientists and clinicians. The extensive illustrations, tables, and in-depth coverage of topics, including discussion of the non-infective aspects of allergic and toxin mediated fungal disease, are designed to aid the understanding of mechanisms and pathology, and extend the usual approach to fungal disease. This textbook is essential reading for microbiologists, research scientists, infectious diseases clinicians, respiratory physicians, and those managing immunocompromised patients. Part of the Oxford Textbook in Infectious Disease and Microbiology series, it is also a useful companion text for students and trainees looking to supplement mycology courses and microbiology training.

Medicinal Plants

Bassam Hassan
Medicinal Plants Book PDF

Author : Bassam Hassan
Publisher : BoD – Books on Demand
Page : 194 pages
File Size : 53,8 Mb
Release : 2020-03-25
Category : Medical
ISBN : 9781789858877

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Medicinal Plants by Bassam Hassan Pdf

This book is focused on clarifying the anticancer effects (i.e., apoptotic, antiproliferative, antimetastatic, antiangiogenic) and mechanisms of most of the medicinal plants found in the world against solid and/or hematological cancers.

Cutaneous Fungal Infections

B. Elewski
Cutaneous Fungal Infections Book PDF

Author : B. Elewski
Publisher : Wiley-Blackwell
Page : 400 pages
File Size : 43,5 Mb
Release : 1998-03-13
Category : Medical
ISBN : 0865425272

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Cutaneous Fungal Infections by B. Elewski Pdf

With greater occurance of fungal infections of the skin, especially in immuno compromised patients, the attention paid to this topic has increased in recent years. The second edition of Cutaneous Fungal Infections answers the need for more information on skin infections and the many new easy-to-use, effective drugs on the market today.

Clotrimazole

Oliss Brown
Clotrimazole Book PDF

Author : Oliss Brown
Publisher : Createspace Independent Publishing Platform
Page : 46 pages
File Size : 43,6 Mb
Release : 2018-08-13
Category : Electronic
ISBN : 1725145790

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Clotrimazole by Oliss Brown Pdf

Treatment of fungal infection, skin infection, Virginal Yeast infection Clotrimazole is known to be an anti-fungal drug that treats various fungi infections like oral thrush, virginal yeast infection, ringworm. It also helps to treat various diseases such as cancer, anti-inflammatory effect in patient, sickle cell. A limiting factor in oral clotrimazole therapy is the high incidence of GIT disturbances and neurological reactions. Clotrimazole is known to be an antifungal drug that helps to treat yeast infections of different kind. It also has different uses in over the counter medicine (OCT). It is used to also treat vagina yeast infection, it can be found in single ingredient topical skin fungus medicines, likewise this medicine called clotrimazole can as well be found in single ingredient vagina yeast infection products. Clotrimazole belongs to the family of drugs called antifungals. It is used to deal with fungal infections of the pores and skin (ringworm, athlete's foot, and jock itch) and nails. It is also used to treat "solar fungus" GRAB YOUR COPY NOW

Diagnosis of Fungal Infections

Johan Maertens,Kieren A. Marr
Diagnosis of Fungal Infections Book PDF

Author : Johan Maertens,Kieren A. Marr
Publisher : CRC Press
Page : 425 pages
File Size : 46,8 Mb
Release : 2007-08-29
Category : Medical
ISBN : 9781420017182

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Diagnosis of Fungal Infections by Johan Maertens,Kieren A. Marr Pdf

Analyzing a key cause of infectious morbidity in immunosuppressed and immunocompromised patients, this source spans the most recent strategies to improve and expedite the diagnosis, identification, and treatment of fungal infections. With authoritative contributions from experienced clinicians in the field, this reference tracks developments in ima