Computational Methods In Molecular Biology

Author : S.L. Salzberg,D.B. Searls,S. Kasif
Publisher : Elsevier
Page : 368 pages
File Size : 47,7 Mb
Release : 1998-06-19
Category : Computers
ISBN : 0080860931

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Computational Methods in Molecular Biology by S.L. Salzberg,D.B. Searls,S. Kasif Pdf

Computational biology is a rapidly expanding field, and the number and variety of computational methods used for DNA and protein sequence analysis is growing every day. These algorithms are extremely valuable to biotechnology companies and to researchers and teachers in universities. This book explains the latest computer technology for analyzing DNA, RNA, and protein sequences. Clear and easy to follow, designed specifically for the non-computer scientist, it will help biologists make better choices on which algorithm to use. New techniques and demonstrations are elucidated, as are state-of-the-art problems, and more advanced material on the latest algorithms. The primary audience for this volume are molecular biologists working either in biotechnology companies or academic research environments, individual researchers and the institutions they work for, and students. Any biologist who relies on computers should want this book. A secondary audience will be computer scientists developing techniques with applications in biology. An excellent reference for leading techniques, it will also help introduce computer scientists to the biology problems. This is an outstanding work which will be ideal for the increasing number of scientists moving into computational biology.

Author : Anonim
Publisher : Unknown
Page : 371 pages
File Size : 45,7 Mb
Release : 1998
Category : Molecular biology
ISBN : 0444803033

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Computational Methods in Molecular Biology by Anonim Pdf

Author : Mario Andrea Marchisio
Publisher : Humana
Page : 255 pages
File Size : 49,6 Mb
Release : 2021-11-27
Category : Science
ISBN : 107160824X

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Computational Methods in Synthetic Biology by Mario Andrea Marchisio Pdf

This second edition book provides complete coverage of the computational approaches currently used in Synthetic Biology. New chapters detail computational methods and algorithms for the design of bio-components, insight on CAD programs, analysis techniques, and distributed systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Computational Methods in Synthetic Biology, Second Edition aims to feature a broad overview of the research areas that can be met in the area of in silico Synthetic Biology.

Author : Bernhard Schölkopf,Koji Tsuda,Jean-Philippe Vert
Publisher : MIT Press
Page : 428 pages
File Size : 43,8 Mb
Release : 2004
Category : Computers
ISBN : 0262195097

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Kernel Methods in Computational Biology by Bernhard Schölkopf,Koji Tsuda,Jean-Philippe Vert Pdf

A detailed overview of current research in kernel methods and their application to computational biology.

Author : Tao Jiang,Ying Xu,Michael Q. Zhang
Publisher : MIT Press
Page : 570 pages
File Size : 44,9 Mb
Release : 2002
Category : Computers
ISBN : 0262100924

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Current Topics in Computational Molecular Biology by Tao Jiang,Ying Xu,Michael Q. Zhang Pdf

A survey of current topics in computational molecular biology. Computational molecular biology, or bioinformatics, draws on the disciplines of biology, mathematics, statistics, physics, chemistry, computer science, and engineering. It provides the computational support for functional genomics, which links the behavior of cells, organisms, and populations to the information encoded in the genomes, as well as for structural genomics. At the heart of all large-scale and high-throughput biotechnologies, it has a growing impact on health and medicine. This survey of computational molecular biology covers traditional topics such as protein structure modeling and sequence alignment, and more recent ones such as expression data analysis and comparative genomics. It combines algorithmic, statistical, database, and AI-based methods for studying biological problems. The book also contains an introductory chapter, as well as one on general statistical modeling and computational techniques in molecular biology. Each chapter presents a self-contained review of a specific subject. Not for sale in China, including Hong Kong.

Author : Guo-Cheng Yuan
Publisher : Humana Press
Page : 271 pages
File Size : 51,8 Mb
Release : 2019-02-14
Category : Science
ISBN : 149399056X

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Computational Methods for Single-Cell Data Analysis by Guo-Cheng Yuan Pdf

This detailed book provides state-of-art computational approaches to further explore the exciting opportunities presented by single-cell technologies. Chapters each detail a computational toolbox aimed to overcome a specific challenge in single-cell analysis, such as data normalization, rare cell-type identification, and spatial transcriptomics analysis, all with a focus on hands-on implementation of computational methods for analyzing experimental data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Methods for Single-Cell Data Analysis aims to cover a wide range of tasks and serves as a vital handbook for single-cell data analysis.

Author : Mourad Elloumi,Costas Iliopoulos,Jason T. L. Wang,Albert Y. Zomaya
Publisher : John Wiley & Sons
Page : 654 pages
File Size : 50,8 Mb
Release : 2015-12-29
Category : Technology & Engineering
ISBN : 9781118893685

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Pattern Recognition in Computational Molecular Biology by Mourad Elloumi,Costas Iliopoulos,Jason T. L. Wang,Albert Y. Zomaya Pdf

A comprehensive overview of high-performance pattern recognition techniques and approaches to Computational Molecular Biology This book surveys the developments of techniques and approaches on pattern recognition related to Computational Molecular Biology. Providing a broad coverage of the field, the authors cover fundamental and technical information on these techniques and approaches, as well as discussing their related problems. The text consists of twenty nine chapters, organized into seven parts: Pattern Recognition in Sequences, Pattern Recognition in Secondary Structures, Pattern Recognition in Tertiary Structures, Pattern Recognition in Quaternary Structures, Pattern Recognition in Microarrays, Pattern Recognition in Phylogenetic Trees, and Pattern Recognition in Biological Networks. Surveys the development of techniques and approaches on pattern recognition in biomolecular data Discusses pattern recognition in primary, secondary, tertiary and quaternary structures, as well as microarrays, phylogenetic trees and biological networks Includes case studies and examples to further illustrate the concepts discussed in the book Pattern Recognition in Computational Molecular Biology: Techniques and Approaches is a reference for practitioners and professional researches in Computer Science, Life Science, and Mathematics. This book also serves as a supplementary reading for graduate students and young researches interested in Computational Molecular Biology.

Author : Adam Liwo
Publisher : Springer
Page : 851 pages
File Size : 45,7 Mb
Release : 2018-12-19
Category : Technology & Engineering
ISBN : 9783319958439

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Computational Methods to Study the Structure and Dynamics of Biomolecules and Biomolecular Processes by Adam Liwo Pdf

This book provides a comprehensive overview of modern computer-based techniques for analyzing the structure, properties and dynamics of biomolecules and biomolecular processes. It is organized in four main parts; the first one deals with methodology of molecular simulations; the second one with applications of molecular simulations; the third one introduces bioinformatics methods and the use of experimental information in molecular simulations; the last part reports on selected applications of molecular quantum mechanics. This second edition has been thoroughly revised and updated to include the latest progresses made in the respective field of research.

Author : Paul Harrison
Publisher : John Wiley & Sons
Page : 230 pages
File Size : 43,9 Mb
Release : 2001-11-28
Category : Science
ISBN : 0471495638

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Computational Methods in Physics, Chemistry and Biology by Paul Harrison Pdf

Eine gut verständliche Einführung in moderne naturwissenschaftliche Rechenmethoden! Nur geringe physikalische Vorkenntnisse voraussetzend, vermittelt der Autor Grundlagen und komplexere Ansätze anhand vieler Beispiele und ausgesprochen praxisnaher Übungsaufgaben. Besprochen werden alle Rechenmethoden, die im Grundstudium erlernt werden sollen, hinsichtlich ihrer Leistungsfähigkeit und ihrer Anwendungsgebiete.

Author : Quentin Vanhaelen
Publisher : Humana
Page : 0 pages
File Size : 43,5 Mb
Release : 2022-12-24
Category : Science
ISBN : 1071617699

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Computational Methods for Estimating the Kinetic Parameters of Biological Systems by Quentin Vanhaelen Pdf

This detailed book provides an overview of various classes of computational techniques, including machine learning techniques, commonly used for evaluating kinetic parameters of biological systems. Focusing on three distinct situations, the volume covers the prediction of the kinetics of enzymatic reactions, the prediction of the kinetics of protein-protein or protein-ligand interactions (binding rates, dissociation rates, binding affinities), and the prediction of relatively large set of kinetic rates of reactions usually found in quantitative models of large biological networks. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of expert implementation advice that leads to successful results. Authoritative and practical, Computational Methods for Estimating the Kinetic Parameters of Biological Systems will be of great interest for researchers working through the challenge of identifying the best type of algorithm and who would like to use or develop a computational method for the estimation of kinetic parameters.

Author : Jason McDermott
Publisher : Humana
Page : 622 pages
File Size : 50,9 Mb
Release : 2009-04
Category : Computers
ISBN : UOM:39015075653454

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Computational Systems Biology by Jason McDermott Pdf

The recent confluence of high throughput methodology for biological data gathering, genome-scale sequencing, and computational processing power has driven a reinvention and expansion of the way we identify, infer, model, and store relationships between molecules, pathways, and cells in living organisms. In Computational Systems Biology, expert investigators contribute chapters which bring together biological data and computational and/or mathematical models of the data to aid researchers striving to create a system that provides both predictive and mechanistic information for a model organism. The volume is organized into five major sections involving network components, network inference, network dynamics, function and evolutionary system biology, and computational infrastructure for systems biology. As a volume of the highly successful Methods in Molecular BiologyTM series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Comprehensive and up-to-date, Computational Systems Biology serves to motivate and inspire all those who wish to develop a complete description of a biological system.

Author : Torsten Schwede
Publisher : World Scientific
Page : 790 pages
File Size : 42,7 Mb
Release : 2008
Category : Science
ISBN : 9789812778789

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Computational Structural Biology by Torsten Schwede Pdf

This is a comprehensive introduction to Landau-Lifshitz equations and Landau-Lifshitz-Maxwell equations, beginning with the work by Yulin Zhou and Boling Guo in the early 1980s and including most of the work done by this Chinese group led by Zhou and Guo since. The book focuses on aspects such as the existence of weak solutions in multi dimensions, existence and uniqueness of smooth solutions in one dimension, relations with harmonic map heat flows, partial regularity and long time behaviors. The book is a valuable reference book for those who are interested in partial differential equations, geometric analysis and mathematical physics. It may also be used as an advanced textbook by graduate students in these fields.

Author : Tobias Sikosek
Publisher : Humana
Page : 0 pages
File Size : 52,8 Mb
Release : 2018-10-09
Category : Science
ISBN : 1493987356

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Computational Methods in Protein Evolution by Tobias Sikosek Pdf

This volume presents a diverse collection of methodologies used to study various problems at the protein sequence and structure level. The chapters in this book look at issues ranging from broad concepts like protein space to specifics like antibody modeling. Topics include point mutations, gene duplication, de novo emergence of new genes, pairwise correlated mutations, ancestral protein reconstruction, homology modelling, protein stability and dynamics, and protein-protein interactions. The book also covers a wide range of computational approaches, including sequence and structure alignments, phylogenies, physics-based and mathematical approaches, machine learning, and more. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and prerequisites, step-by-step, readily reproducible computational protocols (using command line or graphical user interfaces, sometimes including computer code), and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Computational Methods in Protein Evolution is a valuable resource that offers useful workflows and techniques that will help both novice and expert researchers working with proteins computationally.

Author : Srinivas Aluru
Publisher : CRC Press
Page : 1108 pages
File Size : 42,7 Mb
Release : 2005-12-21
Category : Computers
ISBN : 9781420036275

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Handbook of Computational Molecular Biology by Srinivas Aluru Pdf

The enormous complexity of biological systems at the molecular level must be answered with powerful computational methods. Computational biology is a young field, but has seen rapid growth and advancement over the past few decades. Surveying the progress made in this multidisciplinary field, the Handbook of Computational Molecular Biology of

Author : Ralf Blossey
Publisher : CRC Press
Page : 276 pages
File Size : 46,8 Mb
Release : 2006-05-25
Category : Computers
ISBN : 9781420010787

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Computational Biology by Ralf Blossey Pdf

Quantitative methods have a particular knack for improving any field they touch. For biology, computational techniques have led to enormous strides in our understanding of biological systems, but there is still vast territory to cover. Statistical physics especially holds great potential for elucidating the structural-functional relationships in bi