Contributions Of Physiology To The Understanding Of Diabetes

Author : Gaston R. Zahnd,Claes B. Wollheim
Publisher : Springer Science & Business Media
Page : 185 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642604751

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Contributions of Physiology to the Understanding of Diabetes by Gaston R. Zahnd,Claes B. Wollheim Pdf

Recent developments in research on diabetes mellitus embrace basic disciplines such as physiology, biochemistry, morphology and evolving sub-specialities. Fundamental studies on the heterogeneous diabetic syndrome are oriented towards regulatory principles of cell metabolism, genetic control mechanisms of insulin biosynthesis and secretion, as well as autoimmune events implicated in selective destruction of pancreatic ß-cell. In parallel, efforts are made for a better understanding of normal versus impaired biological actions, both of insulin and insulin-like growth factor I, and the translocation process of glucose transporters in insulin-responsive target cells.

Author : Samy I. McFarlane,George L. Bakris
Publisher : Springer Science & Business Media
Page : 196 pages
File Size : 55,9 Mb
Release : 2012-10-19
Category : Medical
ISBN : 9781603273572

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Diabetes and Hypertension by Samy I. McFarlane,George L. Bakris Pdf

Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.

Author : Mark A. Sperling
Publisher : Unknown
Page : 0 pages
File Size : 48,9 Mb
Release : 2005
Category : Children
ISBN : 141602753X

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Diabetes Mellitus in Children by Mark A. Sperling Pdf

Author : Philip Cryer
Publisher : American Diabetes Association
Page : 194 pages
File Size : 41,9 Mb
Release : 2016-07-12
Category : Medical
ISBN : 9781580406499

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Hypoglycemia in Diabetes by Philip Cryer Pdf

Intended for diabetes researchers and medical professionals who work closely with patients with diabetes, this newly updated and expanded edition provides new perspectives and direct insight into the causes and consequences of this serious medical condition from one of the foremost experts in the field. Using the latest scientific and medical developments and trends, readers will learn how to identify, prevent, and treat this challenging phenomenon within the parameters of the diabetes care regimen.

Author : Michael Bliss
Publisher : University of Toronto Press
Page : 320 pages
File Size : 47,6 Mb
Release : 2017-06-22
Category : Medical
ISBN : 9781487516741

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The Discovery of Insulin by Michael Bliss Pdf

The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.

Author : V. Jörgens,M. Porta
Publisher : Karger Medical and Scientific Publishers
Page : 318 pages
File Size : 43,6 Mb
Release : 2020-08-06
Category : Medical
ISBN : 9783318067347

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Unveiling Diabetes - Historical Milestones in Diabetology by V. Jörgens,M. Porta Pdf

A history of diabetology told by renowned contributors, many have themselves already become a part of diabetes history. A must-have for every diabetologist! Diabetologists, diabetes educators, and many interested readers will appreciate this book. What is more, countless celebrations are planned for the 100th anniversary of the discovery of insulin: this book provides numerous illustrations, accounts of personal experiences, and critical remarks on the history of diabetology – in addition to the history of insulin. It spans an arc from antiquity to the work of Claude Bernard, Paul Langerhans, Josef von Mering, Apollinaire Bouchardat, Oskar Minkowski, E.P. Joslin, and F.M. Allen. The history of insulin is presented from the perspective of diabetologists from Scotland, Spain, Germany, and Poland. The history of oral antidiabetics is told by Harald Lebovitz, and the chapter about glitazones by Edwin Gale reads like a spy novel! Pierre Lefèbvre describes the work of the diabetologist Jean Pirart and the history of glucagon. Sir George Alberti has provided a chapter about the therapy of ketoacidosis, to which he himself made groundbreaking contributions. Nephropathy is presented by Hans-Henrik Parving, and Eva Kohner, Ronald Klein and Barbara E.K. Klein have contributed a chapter on retinopathy. Other contemporary topics such diabetes in pregnancy, diabetes technology, psychosocial aspects of diabetes, and the history of the EASD and ADA are also included in this book.

Author : Beatrice Morio,Luc Penicaud,Michel Rigoulet
Publisher : Academic Press
Page : 460 pages
File Size : 40,9 Mb
Release : 2019-04-26
Category : Science
ISBN : 9780128117521

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Mitochondria in Obesity and Type 2 Diabetes by Beatrice Morio,Luc Penicaud,Michel Rigoulet Pdf

Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers. Synthesizes actual knowledge on mitochondrial function Provides an integrated vision of each tissue in the etiology of obesity and type 2 diabetes Identifies the interactive networks that involve alteration in mitochondrial mass and function in disease progression Highlights the role played by mitochondria in the prevention and treatment of obesity and type 2 diabetes

Author : Anil Gupta
Publisher : Elsevier
Page : 321 pages
File Size : 54,7 Mb
Release : 2021-11-17
Category : Medical
ISBN : 9780128203798

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Understanding Insulin and Insulin Resistance by Anil Gupta Pdf

Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance. The design is systematic and meticulous, portraying topics in a flow from simple to complex. This resource is intended for a broad audience spanning across biochemistry, medicine, dentistry, academia, physicians, and research scholars. It extends the approach to biochemistry, physiology, metabolism of insulin along with the coverage of pathophysiology of insulin resistance, its effects on the body tissues, and its analysis on insulin resistance syndrome.

Author : Jonathan C. K. Wells
Publisher : Cambridge University Press
Page : 625 pages
File Size : 51,5 Mb
Release : 2016-07-21
Category : Business & Economics
ISBN : 9781107009479

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The Metabolic Ghetto by Jonathan C. K. Wells Pdf

A multidisciplinary analysis of the role of nutrition in generating hierarchical societies and cultivating a global epidemic of chronic diseases.

Author : Michitoshi Inoue,Masatsugu Hori,Shoichi Imai,Robert M. Berne
Publisher : Springer Science & Business Media
Page : 330 pages
File Size : 47,8 Mb
Release : 2013-11-09
Category : Medical
ISBN : 9784431683674

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Regulation of Coronary Blood Flow by Michitoshi Inoue,Masatsugu Hori,Shoichi Imai,Robert M. Berne Pdf

Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

Author : Arleen Marcia Tuchman
Publisher : Yale University Press
Page : 287 pages
File Size : 46,5 Mb
Release : 2020-08-05
Category : Health & Fitness
ISBN : 9780300228991

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Diabetes by Arleen Marcia Tuchman Pdf

Who gets diabetes and why? An in-depth examination of diabetes in the context of race, public health, class, and heredity Who is considered most at risk for diabetes, and why? In this thorough, engaging book, historian Arleen Tuchman examines and critiques how these questions have been answered by both the public and medical communities for over a century in the United States. Beginning in the late nineteenth century, Tuchman describes how at different times Jews, middle-class whites, American Indians, African Americans, and Hispanic Americans have been labeled most at risk for developing diabetes, and that such claims have reflected and perpetuated troubling assumptions about race, ethnicity, and class. She describes how diabetes underwent a mid-century transformation in the public's eye from being a disease of wealth and "civilization" to one of poverty and "primitive" populations. In tracing this cultural history, Tuchman argues that shifting understandings of diabetes reveal just as much about scientific and medical beliefs as they do about the cultural, racial, and economic milieus of their time.

Author : Boris Draznin
Publisher : American Diabetes Association
Page : 232 pages
File Size : 47,6 Mb
Release : 2016-05-20
Category : Medical
ISBN : 9781580406574

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Managing Diabetes and Hyperglycemia in the Hospital Setting by Boris Draznin Pdf

As the number of patients with diabetes increases annually, it is not surprising that the number of patients with diabetes who are admitted to the hospital also increases. Once in the hospital, patients with diabetes or hyperglycemia may be admitted to the Intensive Care Unit, require urgent or elective surgery, enteral or parenteral nutrition, intravenous insulin infusion, or therapies that significantly impact glycemic control (e.g., steroids). Because many clinical outcomes are influenced by the degree of glycemic control, knowledge of the best practices in inpatient diabetes management is extremely important. The field of inpatient management of diabetes and hyperglycemia has grown substantially in the last several years. This body of knowledge is summarized in this book, so it can reach the audience of hospitalists, endocrinologists, nurses and other team members who take care of hospitalized patients with diabetes and hyperglycemia.

Author : Jahangir Moini
Publisher : Elsevier
Page : 210 pages
File Size : 50,6 Mb
Release : 2019-03-19
Category : Medical
ISBN : 9780128173251

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Epidemiology of Diabetes by Jahangir Moini Pdf

Epidemiology of Diabetes addresses the patterns, risk factors and prevention tactics for the epidemic of diabetes in the US population. Diabetes is a costly and common disease that needs serious attention and awareness. Diabetes causes devastating consequences, such as neuropathy, retinopathy, nephropathy and vasculopathy. This succinct reference focuses on current data and research on diabetes, and is essential reading for diabetes care providers, as well as health care decision-makers. The Centers for Disease Control and Prevention has reported that more than 100 million US adults are living with diabetes or prediabetes, hence this is a timely resource on the topic. Serves as a starting point for medical professionals who are addressing the patterns, risk factors, prevention and treatment of the epidemic of diabetes in the US population Discusses the epidemic and prevalence of diabetes in the United States, covering the disability, burden and mortality of diabetes Covers the epidemiology of nutrition and diet, addressing carbohydrates and fiber, fats, protein, alcohol and nutritional intervention

Author : Richard I. G. Holt,Clive Cockram,Allan Flyvbjerg,Barry J. Goldstein
Publisher : John Wiley & Sons
Page : 1104 pages
File Size : 47,8 Mb
Release : 2017-03-06
Category : Medical
ISBN : 9781118912027

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Textbook of Diabetes by Richard I. G. Holt,Clive Cockram,Allan Flyvbjerg,Barry J. Goldstein Pdf

Now in its fifth edition, the Textbook of Diabetes has established itself as the modern, well-illustrated, international guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the Textbook hosts an unrivalled blend of clinical and scientific content. Highly-experienced editors from across the globe assemble an outstanding set of international contributors who provide insight on new developments in diabetes care and information on the latest treatment modalities used around the world. The fifth edition features an array of brand new chapters, on topics including: Ischaemic Heart Disease Glucagon in Islet Regulation Microbiome and Diabetes Diabetes and Non-Alcoholic Fatty Liver Disease Diabetes and Cancer End of Life Care in Diabetes as well as a new section on Psychosocial aspects of diabetes. In addition, all existing chapters are fully revised with the very latest developments, including the most recent guidelines from the ADA, EASD, DUK and NICE. Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates Via the companion website, readers can access a host of additional online materials such as: 200 interactive MCQ's to allow readers to self-assess their clinical knowledge every figure from the book, available to download into presentations fully searchable chapter pdfs Once again, Textbook of Diabetes provides endocrinologists and diabetologists with a fresh, comprehensive and multi-media clinical resource to consult time and time again.

Author : Lawrence H. Lash,Dean P. Jones
Publisher : Elsevier
Page : 527 pages
File Size : 48,5 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483218618

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Mitochondrial Dysfunction by Lawrence H. Lash,Dean P. Jones Pdf

Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.