Control Of Metabolic Processes

Author : Athel Cornish-Bowden,Maria Luz Cárdenas
Publisher : Springer Science & Business Media
Page : 445 pages
File Size : 49,5 Mb
Release : 2013-11-22
Category : Medical
ISBN : 9781475798562

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Control of Metabolic Processes by Athel Cornish-Bowden,Maria Luz Cárdenas Pdf

THIS BOOK collects together papers given at a NATO Advanced Research Workshop held at Il Ciocco (Lucca), Italy, from the 9th to the 15th April, 1989. It sets out to present the current state of understanding of the principles governing the way fluxes and concentrations are maintained and controlled in metabolic systems. Although this is a topic that has held the interest of biochemists for many years, it is only quite recently that the methods of analysing the kinetics of multi-enzyme pathways developed over the past two decades have come to be widely discussed or applied experimentally. Many biochemists remain sceptical that the new methods offer a real advance (except in complexity) over the landmark discoveries of the 1950s and 1960s relating to inhibition of enzymes at branch-points by the end products of metabolic pathways, and the interpretation of allosteric effects and cooperativity. Even those who have become convinced that the classical ideas provide only the starting point for understanding metabolic control have been by no means unanimous in their assess ment of the direction in which one should advance. In this book we have tried to include all of the current points of view, including the view that the classical theories tell us all that we need to know. We have not seen it as our role as editors to paper over the cracks that exist and to pretend that we can speak to the world with one voice.

Author : Naa Adamafio,Laud Okine,Jonathan Adjimani
Publisher : iUniverse
Page : 160 pages
File Size : 53,6 Mb
Release : 2005-04
Category : Science
ISBN : 9780595340675

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Integration and Control of Metabolism by Naa Adamafio,Laud Okine,Jonathan Adjimani Pdf

Fully understanding the complex process of the integration and control of metabolism in cellular organisms requires knowledge in several fundamental concepts. Drawing on nearly two decades of innovative studies, Doctors Naa Adamafio, Laud Okine, and Jonathan Adjimani specifically target the intricacies of metabolism and provide a comprehensive approach to the subject. The text is divided into three essential areas of study: Fundamentals of metabolic control--dealing with the basic concepts of metabolic control and the role played by regulatory enzymes Control of cellular metabolism--including the regulation of the metabolism of major biomolecules, such as carbohydrates, lipids, and compounds containing nitrogen The integration of metabolism--observing the methods in which various metabolic pathways within and between tissues and organs are integrated Whether you are an undergraduate student in biochemistry, a medical student in your preclinical years, or a teacher in the subject area, Integration and Control of Metabolism is a valuable medical resource.

Author : Keith N. Frayn,Rhys Evans
Publisher : John Wiley & Sons
Page : 392 pages
File Size : 48,6 Mb
Release : 2019-03-13
Category : Medical
ISBN : 9781119331445

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Human Metabolism by Keith N. Frayn,Rhys Evans Pdf

The updated bestselling guide to human metabolism and metabolic regulation The revised and comprehensively updated new edition of Human Metabolism (formerly Metabolic Regulation – A Human Perspective) offers a current and integrated review of metabolism and metabolic regulation. The authors explain difficult concepts in clear and concise terms in order to provide an accessible and essential guide to the topic. This comprehensive text covers a wide range of topics such as energy balance, body weight regulation, exercise, and how the body copes with extreme situations, and illustrates how metabolic regulation allows the human body to adapt to many different conditions. This fourth edition has been revised with a new full colour text design and helpful illustrations that illuminate the regulatory mechanisms by which all cells control the metabolic processes necessary for life. The text includes chapter summaries and additional explanatory text that help to clarify the information presented. In addition, the newly revised edition includes more content on metabolic pathways and metabolic diseases. This important resource: Is a valuable tool for scientists, practitioners and students across a broad range of health sciences including medicine, biochemistry, nutrition, dietetics, sports science and nursing Includes a full colour text filled with illustrations and additional diagrams to aid understanding Offers a companion website with additional learning and teaching resources. Written for students of medicine, biochemistry, nutrition, dietetics, sports science and nursing, Human Metabolism has been revised and updated to provide a comprehensive review of metabolism and metabolic regulation.

Author : David Fell
Publisher : Unknown
Page : 301 pages
File Size : 55,6 Mb
Release : 1997
Category : Electronic
ISBN : OCLC:1025264393

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Understanding the Control of Metabolism by David Fell Pdf

Author : Institute of Medicine,Committee on Military Nutrition Research
Publisher : National Academies Press
Page : 729 pages
File Size : 54,7 Mb
Release : 1997-09-03
Category : Medical
ISBN : 9780309174534

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Emerging Technologies for Nutrition Research by Institute of Medicine,Committee on Military Nutrition Research Pdf

The latest of a series of publications based on workshops sponsored by the Committee on Military Nutrition Research, this book's focus on emerging technologies for nutrition research arose from a concern among scientists at the U.S. Army Research Institute of Environmental Medicine that traditional nutrition research, using standard techniques, centered more on complex issues of the maintenance or enhancement of performance, and might not be sufficiently substantive either to measure changes in performance or to predict the effects on performance of stresses soldiers commonly experience in operational environments. The committee's task was to identify and evaluate new technologies to determine whether they could help resolve important issues in military nutrition research. The book contains the committee's summary and recommendations as well as individually authored chapters based on presentations at a 1995 workshop. Other chapters cover techniques of body composition assessment, tracer techniques for the study of metabolism, ambulatory techniques for the determination of energy expenditure, molecular and cellular approaches to nutrition, the assessment of immune function, and functional and behavioral measures of nutritional status.

Author : Byung Hong Kim,Geoffrey Michael Gadd
Publisher : Cambridge University Press
Page : 509 pages
File Size : 45,8 Mb
Release : 2019-05-16
Category : Medical
ISBN : 9781107171732

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Prokaryotic Metabolism and Physiology by Byung Hong Kim,Geoffrey Michael Gadd Pdf

Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 46,9 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Henry J. Vogel
Publisher : Academic Press
Page : 597 pages
File Size : 52,7 Mb
Release : 2014-05-10
Category : Science
ISBN : 9781483265544

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Metabolic Regulation by Henry J. Vogel Pdf

Metabolic Pathways, Third Edition, Volume V: Metabolic Regulation presents the regulation of metabolism in terms of the control of protein synthesis. This book discusses the significance of the control of metabolism in regard to the remarkable mechanisms involved and to the provision of an effective conceptual framework for appreciating the workings of the cell. Organized into 15 chapters, this edition begins with an overview of the numerous and diversified activities of a living cell. This text then examines the ability of living organisms to regulate the storage and mobilization of metabolizable energy. Other chapters consider the cytochrome system that represents the final common path of oxidation and coupled phosphorylation in the eukaryotic cell. This book discusses as well the profound changes that cell metabolism undergoes during differentiation. The final chapter deals with the chemical and genetic bases of the induction response in Gram-positive bacteria. This book is a valuable resource for biologists and physicians.

Author : Nicholas J. Kruger,Steven A. Hill,R. George Ratcliffe
Publisher : Springer Science & Business Media
Page : 316 pages
File Size : 50,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401148184

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Regulation of Primary Metabolic Pathways in Plants by Nicholas J. Kruger,Steven A. Hill,R. George Ratcliffe Pdf

Over the past decade, advances in molecular biology have provided the impetus for a resurgence of interest in plant metabolism. At a general level, the potential for modifying the quantity or quality of harvestable crop products through genetic manipulation has provided an agronomic rationale for seeking a greater understanding of primary plant metabolism and its regulation. Moreover, the now facile techniques for transformation of many plant species and the consequential capacity to manipulate the amounts of specific individual enzymes within specific cell types provides an exciting direct approach for studying metabolic problems. Such transgenic plants are also becoming invaluable tools in studies at the interface between metabolism and other sub-disciplines such as physiology and ecology. The interest generated in plant metabolism by these developments has also encouraged the re-introduction of more conventional biochemical techniques for metabolic analysis. Finally, in common with other areas of cell biology, the wealth of information that can be obtained at the nucleic acid level has provided the stimulus for identification and characterisation of metabolic processes in far greater detail than previously envisaged. The result of these advances it that researchers now have the confidence to address problems in plant metabolism at levels not previously attempted. This book presents the proceedings of an international conference held on 9-11 January 1997 at St Hugh's College, Oxford under the auspices of the Phytochemical Society of Europe.

Author : Keith N. Frayn,Rhys Evans
Publisher : Wiley-Blackwell
Page : 392 pages
File Size : 49,5 Mb
Release : 2019-06-10
Category : Medical
ISBN : 1119331439

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Human Metabolism by Keith N. Frayn,Rhys Evans Pdf

The updated bestselling guide to human metabolism and metabolic regulation The revised and comprehensively updated new edition of Human Metabolism (formerly Metabolic Regulation – A Human Perspective) offers a current and integrated review of metabolism and metabolic regulation. The authors explain difficult concepts in clear and concise terms in order to provide an accessible and essential guide to the topic. This comprehensive text covers a wide range of topics such as energy balance, body weight regulation, exercise, and how the body copes with extreme situations, and illustrates how metabolic regulation allows the human body to adapt to many different conditions. This fourth edition has been revised with a new full colour text design and helpful illustrations that illuminate the regulatory mechanisms by which all cells control the metabolic processes necessary for life. The text includes chapter summaries and additional explanatory text that help to clarify the information presented. In addition, the newly revised edition includes more content on metabolic pathways and metabolic diseases. This important resource: Is a valuable tool for scientists, practitioners and students across a broad range of health sciences including medicine, biochemistry, nutrition, dietetics, sports science and nursing Includes a full colour text filled with illustrations and additional diagrams to aid understanding Offers a companion website with additional learning and teaching resources. Written for students of medicine, biochemistry, nutrition, dietetics, sports science and nursing, Human Metabolism has been revised and updated to provide a comprehensive review of metabolism and metabolic regulation.

Author : Jens Nielsen
Publisher : Springer
Page : 184 pages
File Size : 52,9 Mb
Release : 2003-07-03
Category : Science
ISBN : 9783540453000

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Metabolic Engineering by Jens Nielsen Pdf

Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.

Author : Kenneth B. Storey
Publisher : John Wiley & Sons
Page : 640 pages
File Size : 48,8 Mb
Release : 2005-02-25
Category : Science
ISBN : 9780471675570

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Functional Metabolism by Kenneth B. Storey Pdf

Functional Metabolism of Cells is the first comprehensive survey of metabolism, offering an in-depth examination of metabolism and regulation of carbohydrates, lipids, and amino acids. It provides a basic background on metabolic regulation and adaptation as well as the chemical logic of metabolism, and covers the interrelationship of metabolism to life processes of the whole organism. The book lays out a structured approach to the metabolic basis of disease, including discussion of the normal pathways of metabolism, altered pathways leading to disease, and use of molecular genetics in diagnosis and treatment of disease. It also takes a unique comparative approach in which human metabolism is a reference for metabolism in microorganisms and plant design, and presents novel coverage of development and aging, and human health and animal adaptation. The final chapter reviews the past and future promise of new genetic approaches to treatment and bioinformatics. This, the most exhaustive treatment of metabolism currently available, is a useful text for advanced undergraduates and graduates in biochemistry, cell/molecular biology, and biomedicine, as well as biochemistry instructors and investigators in related fields.

Author : Sang Yup Lee,Jens Nielsen,Gregory Stephanopoulos
Publisher : John Wiley & Sons
Page : 1075 pages
File Size : 54,5 Mb
Release : 2021-06-02
Category : Science
ISBN : 9783527823451

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Metabolic Engineering by Sang Yup Lee,Jens Nielsen,Gregory Stephanopoulos Pdf

Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.

Author : Samantha Fowler,Rebecca Roush,James Wise
Publisher : Unknown
Page : 618 pages
File Size : 45,8 Mb
Release : 2018-01-07
Category : Science
ISBN : 9888407457

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Concepts of Biology by Samantha Fowler,Rebecca Roush,James Wise Pdf

Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

Author : Myron Mehlman
Publisher : Elsevier
Page : 315 pages
File Size : 54,5 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323141253

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Energy Metabolism and the Regulation of Metabolic Processes in Mitochondria by Myron Mehlman Pdf

Energy Metabolism and the Regulation of Metabolic Processes in Mitochondria contains papers presented at the 1972 symposium on metabolic regulation, held at the University of Nebraska Medical School in Omaha, Nebraska. The contributors provide alternative views and ideas in some aspects of metabolic regulation directly concerned with mitochondrial function. Separating 16 papers into chapters, this book first discusses the general aspects of control of the biological energy regulation and the kinetic and thermodynamic control of mitochondrial electron transport and energy coupling. It then covers significant topics on citric acid cycle, including its replenishment and depletion; anion transport and regulation; dynamics and substrate compartmentation; and feedback control. Other chapters examine the mechanisms of gluconeogenesis, lipogenesis, redox reaction, and phosphorylation in the mitochondria. Discussions on hormonal regulation of selected enzyme system directly related to mitochondrial function are provided in the concluding chapters. Biochemists, physiologists, pharmacologists, physicians, researchers, and all others interested in the concepts of mitochondrial function will find this book of great value.