Core Shell Nanostructures For Drug Delivery And Theranostics

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Core-Shell Nanostructures for Drug Delivery and Theranostics

Author : Maria Focarete,Anna Tampieri
Publisher : Woodhead Publishing
Page : 466 pages
File Size : 55,6 Mb
Release : 2018-06-29
Category : Technology & Engineering
ISBN : 9780081021996

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Core-Shell Nanostructures for Drug Delivery and Theranostics by Maria Focarete,Anna Tampieri Pdf

Core-Shell Nanostructures for Drug Delivery and Theranostics: Challenges, Strategies and Prospects for Novel Carrier Systems contains valuable chapters that deal with the fundamentals of nanotechnology for drug delivery, recent developments and research in core-shell nanoparticles for drug-delivery and theranostic applications, and the potential and applications of core-shell nanofiber. This book is a highly valuable resource for scientists interested in the design and development of innovative drug delivery systems, researchers and graduate/postdoctoral students engaged in biomaterials for drug delivery, and R&D managers in the biomaterials and pharmaceutical industry. Focuses on core-shell nanoparticles and nanofiber for innovative applications, including cancer therapy, controlled release and multi-drug release Considers future prospects and potential new applications of core-shell nanostructures for drug delivery and theranostics Explains the principles and essential concepts of nanotechnology for drug delivery systems

Design of Nanostructures for Theranostics Applications

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 692 pages
File Size : 42,9 Mb
Release : 2018-01-15
Category : Science
ISBN : 9780128136706

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Design of Nanostructures for Theranostics Applications by Alexandru Mihai Grumezescu Pdf

Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry. Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders Assesses the pros and cons of using different nanomaterials for different types of treatment

Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics

Author : Ravichandran Manisekaran
Publisher : Springer
Page : 168 pages
File Size : 49,6 Mb
Release : 2017-10-30
Category : Technology & Engineering
ISBN : 9783319676098

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Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics by Ravichandran Manisekaran Pdf

This thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles.

Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering

Author : Ashutosh Tiwari,Atul Tiwari
Publisher : John Wiley & Sons
Page : 633 pages
File Size : 52,9 Mb
Release : 2013-02-19
Category : Science
ISBN : 9781118644744

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Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering by Ashutosh Tiwari,Atul Tiwari Pdf

This comprehensive volume provides the reader valuable insight into the major areas of biomedical nanomaterials, advanced nanomedicine, nanotheragnostics, and cutting-edge nanoscaffolds. The ability to control the structure of materials allows scientists to accomplish what once appeared impossible before the advent of nanotechnology. It is now possible to generate nanoscopic self-assembled and self-destructive robots for effective utilization in therapeutics, diagnostics, and biomedical implants. Nanoscopic therapeutic systems incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities and they have emerged as the next generation of multifarious nanomedicine to improve the therapeutic outcome including chemo and translational therapy. Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering comprises fifteen chapters authored by senior scientists, and is one of the first books to cover nanotheragnostics, which is the new developmental edge of nanomedicine combining both diagnostic and therapeutic elements at the nano level. This large multidisciplinary reference work has four main parts: biomedical nanomaterials; advanced nanomedicine; nanotheragnostics; and nanoscaffolds technology. This groundbreaking volume also covers: Multifunctional polymeric nanostructures for therapy and diagnosis Metalla-assemblies acting as drug carriers Nanomaterials for management of lung disorders and drug delivery Responsive polymer-inorganic hybrid nanogels for optical sensing, imaging, and drug delivery Core/shell nanoparticles for drug delivery and diagnosis Theranostic nanoparticles for cancer imaging and therapy Magnetic nanoparticles in tissue regeneration Core-sheath fibers for regenerative medicine

Nanostructures for Drug Delivery

Author : Ecaterina Andronescu,Alexandru Mihai Grumezescu
Publisher : Elsevier
Page : 1024 pages
File Size : 48,6 Mb
Release : 2017-03-24
Category : Medical
ISBN : 9780323461498

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Nanostructures for Drug Delivery by Ecaterina Andronescu,Alexandru Mihai Grumezescu Pdf

Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms. Demonstrates how nanostructures are successfully employed in drug delivery stems and as drug delivery agents, allowing biomaterials scientists and biochemists to create more effective drug delivery systems Offers an overview of recent research into the use of nanostructures in drug delivery techniques in a cogent, synthesized way, allowing readers to quickly familiarize themselves with this area Includes examples of how the application of nanostructures have improved the efficiency of drug delivery systems, showing medical scientists how they are beneficial

Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery

Author : Mahdi Karimi,Parham Sahandi Zangabad,Amir Ghasemi,Michael R Hamblin
Publisher : Morgan & Claypool Publishers
Page : 108 pages
File Size : 47,9 Mb
Release : 2015-12-01
Category : Science
ISBN : 9781681740102

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Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery by Mahdi Karimi,Parham Sahandi Zangabad,Amir Ghasemi,Michael R Hamblin Pdf

The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo, this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to externally applied stimuli that usually involve application of physical energy. This physical energy can be applied from outside the body and can either cause cargo release, or can activate the nanostructure to be cytotoxic, or both. The stimuli covered include light of various wavelengths (ultraviolet, visible or infrared), temperature (increased or decreased), magnetic fields (used to externally manipulate nanostructures and to activate them), ultrasound, and electrical and mechanical forces. Finally we discuss the issue of nanotoxicology and the future scope of the field.

Electrospun Polymeric Nanofibers

Author : R. Jayakumar
Publisher : Springer Nature
Page : 468 pages
File Size : 43,5 Mb
Release : 2023-04-27
Category : Technology & Engineering
ISBN : 9783031314032

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Electrospun Polymeric Nanofibers by R. Jayakumar Pdf

This volume deals with the various fabrication techniques, surface functionalization and biomedical applications of polymeric fibers possessing different scale and structure. It provides an overview of fabrication techniques such as Co-axial, Centrifugal, Melt and Yarning to procure multiscale, tubular and layered fibrous scaffold employed for biomedical applications. The chapters in this volume discusse the surface/chemical functionalization of fibers which enhance the biological properties of the fibrous scaffolds as well as the development of hybrid, layered and external stimuli-responsive fibrous scaffolds that hold potential application in biosensor and other biomedical fields. In addition, recent advances and applications of polymeric multiscale fibers in tissue engineering, regenerative medicine and drug delivery are presented. The potential use of fibrous scaffolds in bone, neural, tendon/ligament and cardiac tissue engineering, nanofibers as an antimicrobial wound dressing, employed in cancer theragnostics and in the treatment of skin/periodontal infections are discussed. The volume provides expert knowledge on the fabrication techniques, development of different scale and hybrid structure fibers, surface functionalization, layered and external stimuli responsive fibrous scaffolds. It will be beneficial to material/biomaterials scientists, bioengineering and biotechnologists by providing a better understanding on the subject of the innovative applications of fibrous scaffolds in drug delivery, tissue engineering, wound dressings and regenerative medicine.

Smart Nanovesicles for Drug Targeting and Delivery

Author : Maria Carafa,Carlotta Marianecci
Publisher : MDPI
Page : 198 pages
File Size : 52,8 Mb
Release : 2019-05-20
Category : Medical
ISBN : 9783038978947

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Smart Nanovesicles for Drug Targeting and Delivery by Maria Carafa,Carlotta Marianecci Pdf

We can use the short text on the SI page for the description, or you make slight modifications on it. The description/summary is only for promotion (flyer, distribution channels), and will not be included in the book You can use the short text on the SI page for the description Nanovesicles are highly-promising systems for the delivery and/or targeting of drugs, biomolecules and contrast agents. Despite the fact that initial studies in this area were performed on phospholipid vesicles, there is an ever-increasing interest in the use of other molecules to obtain smart vesicular carriers focusing on strategies for targeted delivery. These systems can be obtained using newly synthesized smart molecules, or by intelligent design of opportune carriers to achieve specific delivery to the site of action. The drug/contrast agent-containing vesicles need to be directed to precise locations within the body to obtain desired magnitude and duration of the therapeutic or diagnostic effect. This spatial control in the delivery might open new avenues to modulate drug activity while avoiding side-effects and to optimize contrast agent properties while avoiding a broad distribution in the organism. However, delivering and targeting active substances into specific tissues and cells is still a challenge in designing novel therapeutic approaches against untreatable disorders, such as tumors and degenerative diseases.

Electrospun Materials and Their Allied Applications

Author : Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri
Publisher : John Wiley & Sons
Page : 544 pages
File Size : 53,9 Mb
Release : 2020-05-27
Category : Technology & Engineering
ISBN : 9781119654865

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Electrospun Materials and Their Allied Applications by Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri Pdf

The aim of this book is to explore the history, fundamentals, manufacturing processes, optimization parameters, and applications of electrospun materials. The book includes various types of electrospun materials such as antimicrobial, smart, bioinspired systems. It focuses on the many application areas for electrospun materials such as energy storage and harvesting, catalysis, biomedical including gene delivery and tissue engineering, separation, adsorption and water treatment technologies, packaging. The book emphasizes the enhanced sustainable properties of electrospun materials, with the challenges and future developments being discussed in detail. The chapters are written by top-class researchers and experts from throughout the world.

Nanoscience

Author : P John Thomas,Neerish Revaprasadu
Publisher : Royal Society of Chemistry
Page : 282 pages
File Size : 55,6 Mb
Release : 2017-08-08
Category : Technology & Engineering
ISBN : 9781788012492

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Nanoscience by P John Thomas,Neerish Revaprasadu Pdf

The field of nanoscience continues to grow at an impressive rate and, with such a vast landscape of material, careful distillation of the most important discoveries will help researchers find the key information they require. Nanoscience Volume 4 provides a critical and comprehensive assessment of the most recent research and opinion from across the globe. Coverage includes diverse topics such as 2D nanomaterials, quantum dot solar cells and core nanoparticles for drug delivery applications. Anyone practising in any nano-allied field, or wishing to enter the nano-world will benefit from this resource, presenting the current thought and applications of nanoscience.

Nanoscience in Medicine Vol. 1

Author : Hemant Kumar Daima,Navya PN,Shivendu Ranjan,Nandita Dasgupta,Eric Lichtfouse
Publisher : Springer Nature
Page : 503 pages
File Size : 44,7 Mb
Release : 2020-01-10
Category : Medical
ISBN : 9783030292072

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Nanoscience in Medicine Vol. 1 by Hemant Kumar Daima,Navya PN,Shivendu Ranjan,Nandita Dasgupta,Eric Lichtfouse Pdf

This book takes a systematic approach to address the gaps relating to nanomedicine and bring together fragmented knowledge on the advances on nanomaterials and their biomedical applicability. In particular, it demonstrates an exclusive compilation of state of the art research with a focus on fundamental concepts, current trends, limitations, and future directions of nanomedicine.

Materials for Biomedical Engineering: Bioactive Materials for Antimicrobial, Anticancer, and Gene Therapy

Author : Alexandru Grumezescu,Alina-Maria Holban
Publisher : Elsevier
Page : 466 pages
File Size : 52,9 Mb
Release : 2019-06-28
Category : Medical
ISBN : 9780128184363

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Materials for Biomedical Engineering: Bioactive Materials for Antimicrobial, Anticancer, and Gene Therapy by Alexandru Grumezescu,Alina-Maria Holban Pdf

Materials for Biomedical Engineering: Bioactive Materials for Antimicrobial, Anticancer, and Gene Therapy offers an up-to-date perspective on recent research findings regarding the application and use of these materials for disease treatment and prevention. Various types of currently investigated bioactive materials, including therapeutic nanostructures and antimicrobial hydrogels are discussed, as are their properties, impact and future role in therapeutic applications. The book will be extremely useful for new researchers who want to explore more information on the use of bioactive materials or for more experienced researchers who are interested in new trends and specific applications. Provides knowledge on the range of bioactive materials available, enabling the reader to make optimal materials selection decisions Contains detailed information on current and proposed applications of the latest bioactive materials to empower readers to design innovative products and processes Presents a strong emphasis on chemistry and the physico-chemical characterization of these materials and their application in antimicrobial, anticancer and gene therapy

Nanoparticle Drug Delivery Systems for Cancer Treatment

Author : Hala Gali-Muhtasib,Racha Chouaib
Publisher : CRC Press
Page : 179 pages
File Size : 49,9 Mb
Release : 2020-02-19
Category : Medical
ISBN : 9781000681413

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Nanoparticle Drug Delivery Systems for Cancer Treatment by Hala Gali-Muhtasib,Racha Chouaib Pdf

In recent years, nanoparticles—bionanomaterials with specific physicochemical properties—have gained a great deal of scientific interest owing to their unique structure. Nanoparticle-based drugs are now widely regarded as a safer, more precise, and more effective mode of cancer therapy, considering their ability to enhance drug bioavailability, improve site-specific drug delivery, and protect nontarget tissues from toxic therapeutic drugs. This book compiles and details cutting-edge research in nanomedicine from an interdisciplinary team of international cancer researchers who are currently revolutionizing drug delivery techniques through the development of nanomedicines and nanotheranostics. Edited by Hala Gali-Muhtasib and Racha Chouaib, two prominent cancer researchers, this book will appeal to anyone involved in nanotechnology, cancer therapy, or drug delivery research.

New Insights into Glioblastoma

Author : Carla Vitorino,Carmen Balana,Célia Cabral
Publisher : Elsevier
Page : 788 pages
File Size : 45,8 Mb
Release : 2023-05-17
Category : Science
ISBN : 9780323999427

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New Insights into Glioblastoma by Carla Vitorino,Carmen Balana,Célia Cabral Pdf

New Insights into Glioblastoma: Diagnosis, Therapeutics and Theranostics provides a compendium of recent diagnostic and therapeutic advances in GBM, encompassing a pipeline of compounds and (bio) nanotechnology strategies that have stood out with potential increased antitumoral activity and capability to cross the blood-brain barrier. Issues and challenges related to their translation into the clinical practice and their contribution to the increase in survival rates and well-being of patients are addressed. This is a valuable resource for graduate students, oncologists, cancer researchers and members of the biomedical field who need to learn more on recent developments on the management of glioblastoma. The book is split in three parts: Diagnosis, focusing on biomarkers and techniques such PET/MRI, infrared thermography, and deep neural networks; Therapeutics, discussing new chemical entities, as natural products and repurposed drugs, and new formulation approaches, as nanotechnology-based and microRNA approaches; and Theranostics, explaining the role of omics, system-based approaches, and glioblastoma microenvironment. Provides guidance towards recent advances of new chemical entities and delivery strategies targeted to glioblastoma Includes overviews to help readers apply information in their research Encompasses summarizing diagrams and real-world examples to facilitate comprehension and enhance the applicability of the content

A Comprehensive Guide to Nanoparticles in Medicine

Author : Rituparna Acharya
Publisher : Bentham Science Publishers
Page : 199 pages
File Size : 45,7 Mb
Release : 2021-06-28
Category : Medical
ISBN : 9781681088365

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A Comprehensive Guide to Nanoparticles in Medicine by Rituparna Acharya Pdf

This handbook explains the application of nanoparticles in medical diagnosis and treatment. It is a ready reference on the subject, starting with the introduction to nanoparticles and progressing to synthetic procedures for nanotherapeutics, human disease diagnosis and nanocarrier-based drug delivery. The book also covers information about specific nanoparticle conjugates, in which nanoparticles are combined with drugs or nucleic acid strands (DNA, siRNAs, shRNAs, miRNAs) as well as topics of relevant to this field such as immunotherapy and vaccination development strategies. Each chapter also provides references for further reading. A Comprehensive Guide to Nanoparticles in Medicine is an ideal resource for scholars in medicine, pharmacology and technology who require an understanding to some basic facets of nanoparticles.