Defects Of Secretion In Cystic Fibrosis

Author : Carsten Schultz
Publisher : Springer Science & Business Media
Page : 185 pages
File Size : 49,7 Mb
Release : 2007-07-13
Category : Medical
ISBN : 9780387232508

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Defects of Secretion in Cystic Fibrosis by Carsten Schultz Pdf

Defects in Secretion of Cystic Fibrosis presents an overview on current research from leading experts in North America and Europe. This update on cystic fibrosis provides in depth original work as well as review material on many of the relevant physiological and molecular topics in the field. Subjects covered include the interplay of the various epithelial ion channels, the underlying intracellular signal transduction, mucus secretion, and novel approaches to develop drugs against cystic fibrosis. This book brings together physicians, physiologists, and other scientists involved in basic research, from molecular biology to drug design and introduces novel investigative and therapeutic aspects of secretion disorders relevant in cystic fibrosis and related diseases. This book will be of interest to Molecular biologists, physiologists, scientists working in pharmaceutical research and drug developement, physicians and researchers in Cystic fibrosis and related diseases.

Author : Venkataramana K Sidhaye,Michael Koval
Publisher : Academic Press
Page : 276 pages
File Size : 55,9 Mb
Release : 2017-03-09
Category : Medical
ISBN : 9780128038819

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Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease by Venkataramana K Sidhaye,Michael Koval Pdf

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences

Author : Simon Hart,Mike Greenstone
Publisher : Springer
Page : 367 pages
File Size : 47,6 Mb
Release : 2018-09-04
Category : Medical
ISBN : 9783319941271

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Foundations of Respiratory Medicine by Simon Hart,Mike Greenstone Pdf

This book meets the need for a resource that covers the core knowledge required to pass the SCE exam, which includes the broad field of respiratory medicine. This book is also highly applicable to core medical trainees sitting their MRCP examinations. The format is ideal for effective exam revision with individual chapters covering the key points of each condition in sufficient (but not excessive) detail. Examples of imaging (CXR, CT, PET-CT) are utilised to illustrate cases and descriptions of modern respiratory intervention such as the EBUS/EUS-guided sampling and medical thoracoscopy is included in this essential exam resource.

Author : Anonim
Publisher : Unknown
Page : 6 pages
File Size : 51,8 Mb
Release : 1995
Category : Cystic fibrosis
ISBN : UCSD:31822021857024

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Facts about Cystic Fibrosis by Anonim Pdf

Author : Richard K. Albert,Stephen G. Spiro,James R. Jett
Publisher : Elsevier Health Sciences
Page : 1031 pages
File Size : 44,9 Mb
Release : 2008-04-16
Category : Medical
ISBN : 9780323070942

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Clinical Respiratory Medicine by Richard K. Albert,Stephen G. Spiro,James R. Jett Pdf

This comprehensive clinical textbook examines all aspects of respiratory medicine. The editors take a practical approach to the diagnosis and management of patients with the full range of pulmonary disorders, making this your ideal source for reference in clinical practice. Fully revised, this essential volume includes new chapters on PET imaging, implications of genetic research, oxygen therapy, and rehabilitation. Now an Expert Consult title, it comes with access to the complete contents of the book online, including all of the book’s images, downloadable for use in presentations. Provides complete clinical coverage so you can Better manage and treat patients with pulmonary disease. Uses templated, clinical chapters for consistent, concise, essential information. Includes coverage that reflects the way you practice medicine today with critical information relevant to everyday practice. Utilizes diagnostic algorithms to help you find critical information and at a glance. Includes new chapters on PET imaging, implications of genetic research, oxygen therapy, and rehabilitation to keep you up to date. Includes access to the complete contents of the book online, including all of the book’s images, downloadable for use in presentations.

Author : Ross W. Shepherd,Geoffrey J. Cleghorn
Publisher : CRC Press
Page : 192 pages
File Size : 44,8 Mb
Release : 1989-09-30
Category : Medical
ISBN : 0849369541

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Cystic Fibrosis by Ross W. Shepherd,Geoffrey J. Cleghorn Pdf

This comprehensive text focuses on the nature of malnutrition in Cystic Fibrosis (CF), its manage-ment and prevention, and on the interrelated topic of gastroin-testinal manifestations of CF, many of which have only recently been characterized and defined. This valuable book serves as a basis for subsequent research and the institution of programs to reverse or prevent nutritional and gastrointestinal manifesta-tion. It is a welcome new text for direct-care givers of CF pa-tients, particularly physicians, gastroenterologists, and nutri-tionists as well as researchers.

Author : Stefano Guandalini,Anil Dhawan,David Branski
Publisher : Springer
Page : 889 pages
File Size : 51,9 Mb
Release : 2015-09-30
Category : Medical
ISBN : 9783319171692

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Textbook of Pediatric Gastroenterology, Hepatology and Nutrition by Stefano Guandalini,Anil Dhawan,David Branski Pdf

This textbook provides a comprehensive and state-of-the-art overview of the major issues specific to the field of pediatric gastroenterology, hepatology, and nutrition. The first part of the book, Gastroenterology and Nutrition, presents in a systematic way the overall scope of issues encountered by children (newborn to teenagers) suffering from disorders of the gastrointestinal tract, pancreas and/or presenting nutritional issues. These chapters are structured in logical sections to facilitate consultation and include major topics ranging from congenital disorders to gastrointestinal problems of the newborn, infectious diseases of the gastrointestinal tract, and approach to nutritional problems in the various pediatric ages. The second part of the book, Hepatology, is articulated in a series of chapters which present a comprehensive review of congenital and acquired disorders of the biliary tract and liver. This section also includes a critical analysis of available diagnostic and therapeutic procedures and future perspectives. Written by experts in the field, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition: A Comprehensive Guide to Practice constitutes a much needed, innovative resource combining updated, reliable and comprehensive information with agile consultation for a streamlined approach to the care of children with such disorders.

Author : Edward C.C. Wong,Dennis J. Dietzen,Michael J. Bennett,Shannon Haymond
Publisher : Academic Press
Page : 1172 pages
File Size : 47,8 Mb
Release : 2021-05-13
Category : Science
ISBN : 9780128179635

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Biochemical and Molecular Basis of Pediatric Disease by Edward C.C. Wong,Dennis J. Dietzen,Michael J. Bennett,Shannon Haymond Pdf

Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases. Provides a fully-updated resource with more color illustrations Focuses on the biochemical and molecular basis of disease as well as the analytical techniques Defines important differences in the pathophysiology of diseases, comparing childhood with adult

Author : Maitham Khajah
Publisher : BoD – Books on Demand
Page : 182 pages
File Size : 51,9 Mb
Release : 2017-06-07
Category : Medical
ISBN : 9789535131953

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Role of Neutrophils in Disease Pathogenesis by Maitham Khajah Pdf

This book highlights the important role of neutrophils in health as well as in the pathogenesis of various diseases. Section 1 provides a general background information regarding the mechanisms and various triggers of neutrophil extracellular traps (NETs) formation and their role in various infectious and noninfectious diseases (such as postinjury inflammation). Section 2 provides recent evidence regarding the role of neutrophils in the pathogenesis as well as a therapeutic target for selected disease conditions such as periodontal diseases, rheumatoid arthritis, and cystic fibrosis. Section 3 describes the anti-inflammatory properties of neutrophils with focus regarding their role in graft versus host disease. This book provides a wider picture with regard to the importance of this immune cell type in various diseases with focus on one of its recently discovered properties, NETs. Therapeutic targets aimed to modulate neutrophil functions might provide novel approaches in the treatment of various diseases of infectious and noninfectious origin.

Author : Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri
Publisher : Cambridge University Press
Page : 995 pages
File Size : 51,7 Mb
Release : 2007-05-07
Category : Medical
ISBN : 9781139464031

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Liver Disease in Children by Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri Pdf

Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

Author : Clemente J. Britto,Jennifer L. Taylor-Cousar
Publisher : Elsevier Health Sciences
Page : 281 pages
File Size : 54,9 Mb
Release : 2022-11-09
Category : Medical
ISBN : 9780323849623

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Advances in Cystic Fibrosis, An Issue of Clinics in Chest Medicine, E-Book by Clemente J. Britto,Jennifer L. Taylor-Cousar Pdf

In this issue of Clinics in Chest Medicine, guest editors Drs. Clemente J. Britto and Jennifer L. Taylor-Cousar bring their considerable expertise to Advances in Cystic Fibrosis. Top experts in the field cover key topics such as genetics of cystic fibrosis (CF): clinical implications; innate and adaptive immunity in CF; novel applications of biomarkers and personalized medicine to define the spectrum of CF; emerging approaches to understand CF pathogenesis; and more. Contains 18 relevant, practice-oriented topics including novel approaches to multidrug resistant infections in CF; clinical outcomes of highly-effective modulator therapy; nontuberculous mycobacterial infections in CF; management of mental health in CF; sexual and reproductive health in CF; nutritional management in CF; transitions of care in CF; and more. Provides in-depth clinical reviews on advances in cystic fibrosis, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author : Kevin L. Kirk,David C. Dawson
Publisher : Springer Science & Business Media
Page : 236 pages
File Size : 54,6 Mb
Release : 2003-10-31
Category : Science
ISBN : 0306478374

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The Cystic Fibrosis Transmembrane Conductance Regulator by Kevin L. Kirk,David C. Dawson Pdf

The CFTR chloride channel is one of the most well studied transport proteins in biology. Yet there remain many mysteries about the functional properties and biological roles of this ABC transporter. The Cystic Fibrosis Transmembrane Conductance Regulator addresses a select series of `hot' topics that relate to the function of CFTR, and the links between CFTR dysfunction and human disease (i.e., cystic fibrosis). The timeliness of these topics distinguishes this collection from previous volumes of this type. Given the general interest in CFTR, this collection will appeal to a broad readership with interests in CFTR, cystic fibrosis, ion channels and ABC transporters.

Author : Richard B. Moss
Publisher : Springer Science & Business Media
Page : 258 pages
File Size : 52,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461204756

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Cystic Fibrosis by Richard B. Moss Pdf

This work is concerned with Cystic Fibrosis (CF), the most common fatal genetic disease in the Caucasian population. The decade of the 1980s was one of spectacular progress in understanding the genetic and molecu lar basis of CF. The research breakthroughs of the decade began with the first fundamental insights, published in 1981-1983, into the basic cellular pathophysiology of CF with demonstrations of altered ion transport in spe cialized exocrine epithelial tissues (1-3). Research progress shifted into a triumph of "reverse genetics," using restriction-fragment-Iength polymor phism DNA technology (4), with the localization of the CF gene to a region of chromosome 7 (5-7). Understanding, accelerated by an explOSion of in vitro methodologies for epithelial cell culture and transformation, allowed and physiological studies (8-11); these focused, controlled biochemical with increasing precision, on the molecular pathology of distal steps in the regulatory pathways for epithelial ion transport (12-19). Finally, the "end of the beginning" occurred in late 1989 with one of the great achievements of molecular genetics, the isolation and cloning of the CF gene (20). As a result, we now have a CF gene product, the cystic fibrosis transmembrane regulator (CFfR), possessing predicted amino acid sequence, suggested tertiary structure, and possible transmembrane transport function (21). These amazing developments have set the stage for the next round of advances, which surely will include: 1.

Author : Margaret Hodson,Andrew Bush,Duncan Geddes
Publisher : CRC Press
Page : 523 pages
File Size : 51,6 Mb
Release : 2012-12-11
Category : Medical
ISBN : 9781444113693

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Cystic Fibrosis, Third Edition by Margaret Hodson,Andrew Bush,Duncan Geddes Pdf

This international and authoritative work, which brings together current knowledge in the field of cystic fibrosis, has become established in previous editions as a leading reference in the field. The third edition continues to provide everything that the clinician or allied health professional treating patients with cystic fibrosis will need in a single manageable volume. Thoroughly revised and updated throughout, it reflects the significant advances that have been made in the field since the second edition published in 2000. Cystic Fibrosis evaluates in detail the basic science that underlies the disease and its progression, putting it into a clinical context. Diagnostic and clinical aspects are covered in depth, as are monitoring the condition and the importance of multi-disciplinary care, reflected in the sections into which the new edition has been sub-divided to improve accessibility. Future developments, including novel therapies, are covered in a concluding section. The clinical areas have been much expanded, with the introduction of separate chapters covering sleep, lung mechanics and the work of breathing, upper airway disease, insulin deficiency and diabetes, bone disease, and sexual and reproductive issues. A new section on monitoring discusses the use of databases to improve patient care, and covers monitoring in different age groups, exercise testing and the outcomes of clinical trials in these areas. Separate chapters are devoted to paramedical issues, including nursing, physiotherapy, psychology, and palliative and spiritual care. Throughout, the emphasis is on providing an up-to-date and balanced review of both the clinical and basic sciences aspects of the subject, and to reflect the multi-disciplinary nature of the cystic fibrosis care team. Drawing on the expertise of a team of international specialists from a variety of backgrounds, the third edition of Cystic Fibrosiswill continue to find a broad readership among respiratory physicians, paediatricians, specialist nurses and other health professionals working with patients with cystic fibrosis.

Author : Prashant Mohite,Anna Reed,André Simon
Publisher : BoD – Books on Demand
Page : 126 pages
File Size : 40,7 Mb
Release : 2021-06-09
Category : Medical
ISBN : 9781838810733

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Cystic Fibrosis by Prashant Mohite,Anna Reed,André Simon Pdf

Cystic fibrosis, a genetic disorder in children and young adults, is a multisystemic disease that mainly affects the lungs. Advances and improvements in the diagnosis and management of this condition have led to increased overall and symptom-free survival in cystic fibrosis patients. This book examines recent advances in the field and presents an evidence-based approach to the management of cystic fibrosis.