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Based on extensive participant observation research, a life-history model is presented to explain why very few of those who come into contact with narcotics become problematic consumers; that is make drugs one of the most central elements in their lives. The model covers four stages in the deviant career; two preceding and two subsequent to the individual's narcotics debut. Prohibition and harm reduction as models for intervention are presented, and the implications for drug policy of the life-history model are discussed.
Author : Edward D. Zanders Publisher : Springer Science & Business Media Page : 396 pages File Size : 55,6 Mb Release : 2011-07-08 Category : Medical ISBN : 9781441999023
The Science and Business of Drug Discovery by Edward D. Zanders Pdf
The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the nineteen chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has been written to guide the reader towards the most appropriate information sources, including those listed in the two appendices. The following topics are covered: Different types of drugs: from small molecules to stem cells Background to chemistry of small and large molecules Historical background to drug discovery, pharmacology and biotechnology The drug discovery pipeline: from target discovery to marketed medicine Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology transfer executives, recruiters and pharmaceutical translators.
Demystifying Opioid Conversion Calculations by Mary Lynn McPherson Pdf
Have you ever wondered if you calculated your patient’s dosage correctly? Against a backdrop of the growing scrutiny of appropriate dosages, this textbook takes a fresh, new approach to helping health professionals strengthen care to and possibly save the lives of patients living with pain. This easy-to-understand and often humorous book is the most comprehensive to-date on opioid calculations for pain management and palliative care. It carefully walks clinicians through a five-step process for performing opioid conversion calculations in the real-world situations they often see. The book has case examples, simple charts and tables, and practice problems throughout on topics such as:· difficult conversions for methadone, fentanyl, PCA, and neuraxial opioid therapy· conversions between routes and dosage formulations of the same opioids and different opioids· titrating opioid dosages up and down to include dosage change and timing· calculating doses for rescue opioid therapy Written by pain management expert Dr. Mary Lynn McPherson, the book gives helpful tips that practitioners should incorporate into their practices. It is a must for clinicians at all levels: hospice and palliative care physicians, physician’s assistants, nurses, nurse practitioners, and pharmacists. Clinicians will come away with more confidence in doing the calculations, and higher service levels from the improvement in care.
A creature of Jewish mythology, a golem is an animated being made by man from clay and water who knows neither his own strength nor the extent of his ignorance. Like science and technology, the subjects of Harry Collins and Trevor Pinch's previous volumes, medicine is also a golem, and this Dr. Golem should not be blamed for its mistakes - they ...
Searching for the ultimate stimulant? Something you can have on the bus in the morning or in the ambient comfort of your own home? The latest User's Guide - a totally natural and controlled experience - is just what you've been looking for. It contains everything you always wanted to know about drugs but were afraid to ask: The history of recreational drugs, a catalogue of natural highs and pharmaceuticals, the physiological effects, drugs and religion, drugs and the law, drug customs from around the world, trafficking drugs, drugs in literature, film and art, famous drug takers, drug slang, urban myths, drug legends and horror stories, quotations, tales of outrageous behaviour and a kilo of curious facts and figures. Did you know that- --Scientists have found traces of marijuana among Shakespeare's personal effects--Victorian prime minister Lord Rosebery would snort cocaine to help pep up his public speaking
Communicating about Alcohol and Other Drugs by Elaine Bratic Arkin Pdf
Summarizes knowledge about the characteristics, knowledge, attitudes, and practices of certain audiences of children who are at a higher risk for drug and alcohol abuse. Also discusses channels, sources, materials and messages and offers ideas for reaching these groups. Chapters cover the general category of youth from high-risk environments, looking specifically at Black and Hispanic/Latino children, and influences on them such as parents and primary care physicians. Includes case studies, messages and materials review process, and intermediary organizations.
In 2000, the U.S. passed a major aid package that was going to help Colombia do it all: cut drug trafficking, defeat leftist guerrillas, support peace, and build democracy. More than 80% of the assistance, however, was military aid, at a time when the Colombian security forces were linked to abusive, drug-trafficking paramilitary forces. Drugs, Thugs, and Diplomats examines the U.S. policymaking process in the design, implementation, and consequences of Plan Colombia, as the aid package came to be known. Winifred Tate explores the rhetoric and practice of foreign policy by the U.S. State Department, the Pentagon, Congress, and the U.S. military Southern Command. Tate's ethnography uncovers how policymakers' utopian visions and emotional entanglements play a profound role in their efforts to orchestrate and impose social transformation abroad. She argues that U.S. officials' zero tolerance for illegal drugs provided the ideological architecture for the subsequent militarization of domestic drug policy abroad. The U.S. also ignored Colombian state complicity with paramilitary brutality, presenting them as evidence of an absent state and the authentic expression of a frustrated middle class. For rural residents of Colombia living under paramilitary dominion, these denials circulated as a form of state terror. Tate's analysis examines how oppositional activists and the policy's targets—civilians and local state officials in southern Colombia—attempted to shape aid design and delivery, revealing the process and effects of human rights policymaking.
The Role of Community-Mindedness in the Self-Regulation of Drug Cultures by Anke Stallwitz Pdf
This book analyzes heroin users and the drug subculture on the Shetland Islands, an area known for its geographical remoteness, rural character and relative wealth. It fills the scientific gap created by the conventional research in heroin research, which is usually conducted in urban areas and relies on treatment and prison populations. Based on qualitative, in-depth interviews with twenty-four heroin users, this book depicts and analyzes the nature and historical development of the local heroin scene. It illustrates the features and internal structures of the subculture, and it examines the manner in which both are influenced by the location-specific geographical, cultural and socio-economic conditions. It thus reveals complex causal associations that are hard to recognize in urban environments. Complete with a list of references used and recommendations for future research, this book is a vital tool for progressive and pragmatic approaches to policy, intervention and research in the field of illicit drug use.
The anthology is designed as a starting point for academic debate about illegal drugs. The 25 reprinted articles cover reducing harm and reduction, law enforcement, supply reduction, the European Union's drug policies, and terrorism and drugs. Each appends suggested topics for debate. They are not i
Take as Directed by Rhonda Church,Neil MacKinnon Pdf
A detailed account of how to navigate Canada's health care system'especially in relation to medication safety'this is a firsthand description of the inner workings of the nation's doctor's offices, pharmacies, hospitals, and more. This definitive resource outlines the current situation; identifies key safety and efficacy issues; proposes a means for helping patients each step of the way; and offers information on programs, tools, and techniques available to them.
“Hart’s argument that we need to drastically revise our current view of illegal drugs is both powerful and timely . . . when it comes to the legacy of this country’s war on drugs, we should all share his outrage.” —The New York Times Book Review From one of the world's foremost experts on the subject, a powerful argument that the greatest damage from drugs flows from their being illegal, and a hopeful reckoning with the possibility of their use as part of a responsible and happy life Dr. Carl L. Hart, Ziff Professor at Columbia University and former chair of the Department of Psychology, is one of the world's preeminent experts on the effects of so-called recreational drugs on the human mind and body. Dr. Hart is open about the fact that he uses drugs himself, in a happy balance with the rest of his full and productive life as a researcher and professor, husband, father, and friend. In Drug Use for Grown-Ups, he draws on decades of research and his own personal experience to argue definitively that the criminalization and demonization of drug use--not drugs themselves--have been a tremendous scourge on America, not least in reinforcing this country's enduring structural racism. Dr. Hart did not always have this view. He came of age in one of Miami's most troubled neighborhoods at a time when many ills were being laid at the door of crack cocaine. His initial work as a researcher was aimed at proving that drug use caused bad outcomes. But one problem kept cropping up: the evidence from his research did not support his hypothesis. From inside the massively well-funded research arm of the American war on drugs, he saw how the facts did not support the ideology. The truth was dismissed and distorted in order to keep fear and outrage stoked, the funds rolling in, and Black and brown bodies behind bars. Drug Use for Grown-Ups will be controversial, to be sure: the propaganda war, Dr. Hart argues, has been tremendously effective. Imagine if the only subject of any discussion about driving automobiles was fatal car crashes. Drug Use for Grown-Ups offers a radically different vision: when used responsibly, drugs can enrich and enhance our lives. We have a long way to go, but the vital conversation this book will generate is an extraordinarily important step.
The Science and Business of Drug Discovery by Edward D. Zanders Pdf
The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the twenty chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has been written to guide the reader towards the most appropriate information sources, including those listed in the two appendices. The following topics are covered: Different types of drugs: from small molecules to stem cells Background to chemistry of small and large molecules Historical background to drug discovery, pharmacology and biotechnology The drug discovery pipeline: from target discovery to marketed medicine Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology transfer executives, recruiters and pharmaceutical translators
Demystifying Drug Dosing in Obese Patients by Brandon R Shank,Zimmerman E David Pdf
With Demystifying Drug Dosing in Obese Patients, that resource you need is here, delivering: Fully-referenced dosing recommendations for specific drugs Dedicated chapters on antimicrobial dosing, anticoagulants and antiplatelets, antiepileptics, analgesics, antineoplastic medicines, and more Guidance on immunosuppression and medication absorption in bariatric surgery Tips for adult, pediatric, ambulatory, acute, and critical care Pharmacokinetic parameters in obese patients
Demystifying Drug Dosing in Renal Dysfunction by Branden D. Nemecek Pdf
Chronic kidney disease affects approximately 30 million adults in the United States. Demystifying Drug Dosing in Renal Dysfunction supports your clinical decision process with guidance on dosage adjustments and monitoring in renal dysfunction for medications, subpopulations, and renal replacement modalities. This time-saving resource provides helpful tips and support for a range of clinical situations, including: Antiepileptics, Cardiovascular disease, Co-morbidities associated with chronic kidney disease, Critical illness, Infectious diseases, Oncology, Pain management, Pediatrics, Psychiatry, Therapeutic plasma exchange, Transplantation Book jacket.
