Design And Analysis Of Experiments And Observational Studies Using R

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Design and Analysis of Experiments and Observational Studies using R

Author : Nathan Taback
Publisher : CRC Press
Page : 329 pages
File Size : 48,9 Mb
Release : 2022-03-10
Category : Mathematics
ISBN : 9781000554199

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Design and Analysis of Experiments and Observational Studies using R by Nathan Taback Pdf

Introduction to Design and Analysis of Scientific Studies exposes undergraduate and graduate students to the foundations of classical experimental design and observational studies through a modern framework - The Rubin Causal Model. A causal inference framework is important in design, data collection and analysis since it provides a framework for investigators to readily evaluate study limitations and draw appropriate conclusions. R is used to implement designs and analyse the data collected. Features: Classical experimental design with an emphasis on computation using tidyverse packages in R. Applications of experimental design to clinical trials, A/B testing, and other modern examples. Discussion of the link between classical experimental design and causal inference. The role of randomization in experimental design and sampling in the big data era. Exercises with solutions. Instructor slides in RMarkdown, a new R package will be developed to be used with book, and a bookdown version of the book will be freely available. The proposed book will emphasize ethics, communication and decision making as part of design, data analysis, and statistical thinking.

Design and Analysis of Experiments with R

Author : John Lawson
Publisher : CRC Press
Page : 629 pages
File Size : 54,8 Mb
Release : 2014-12-17
Category : Mathematics
ISBN : 9781498728485

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Design and Analysis of Experiments with R by John Lawson Pdf

Design and Analysis of Experiments with R presents a unified treatment of experimental designs and design concepts commonly used in practice. It connects the objectives of research to the type of experimental design required, describes the process of creating the design and collecting the data, shows how to perform the proper analysis of the data,

Design and Analysis of Experiments and Observational Studies using R

Author : Nathan Taback
Publisher : CRC Press
Page : 293 pages
File Size : 50,6 Mb
Release : 2022-03-10
Category : Mathematics
ISBN : 9781000554175

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Design and Analysis of Experiments and Observational Studies using R by Nathan Taback Pdf

Introduction to Design and Analysis of Scientific Studies exposes undergraduate and graduate students to the foundations of classical experimental design and observational studies through a modern framework - The Rubin Causal Model. A causal inference framework is important in design, data collection and analysis since it provides a framework for investigators to readily evaluate study limitations and draw appropriate conclusions. R is used to implement designs and analyse the data collected. Features: Classical experimental design with an emphasis on computation using tidyverse packages in R. Applications of experimental design to clinical trials, A/B testing, and other modern examples. Discussion of the link between classical experimental design and causal inference. The role of randomization in experimental design and sampling in the big data era. Exercises with solutions. Instructor slides in RMarkdown, a new R package will be developed to be used with book, and a bookdown version of the book will be freely available. The proposed book will emphasize ethics, communication and decision making as part of design, data analysis, and statistical thinking.

Design of Observational Studies

Author : Paul R. Rosenbaum
Publisher : Springer Nature
Page : 552 pages
File Size : 41,8 Mb
Release : 2020-07-13
Category : Mathematics
ISBN : 9783030464059

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Design of Observational Studies by Paul R. Rosenbaum Pdf

This second edition of Design of Observational Studies is both an introduction to statistical inference in observational studies and a detailed discussion of the principles that guide the design of observational studies. An observational study is an empiric investigation of effects caused by treatments when randomized experimentation is unethical or infeasible. Observational studies are common in most fields that study the effects of treatments on people, including medicine, economics, epidemiology, education, psychology, political science and sociology. The quality and strength of evidence provided by an observational study is determined largely by its design. Design of Observational Studies is organized into five parts. Chapters 2, 3, and 5 of Part I cover concisely many of the ideas discussed in Rosenbaum’s Observational Studies (also published by Springer) but in a less technical fashion. Part II discusses the practical aspects of using propensity scores and other tools to create a matched comparison that balances many covariates, and includes an updated chapter on matching in R. In Part III, the concept of design sensitivity is used to appraise the relative ability of competing designs to distinguish treatment effects from biases due to unmeasured covariates. Part IV is new to this edition; it discusses evidence factors and the computerized construction of more than one comparison group. Part V discusses planning the analysis of an observational study, with particular reference to Sir Ronald Fisher’s striking advice for observational studies: "make your theories elaborate." This new edition features updated exploration of causal influence, with four new chapters, a new R package DOS2 designed as a companion for the book, and discussion of several of the latest matching packages for R. In particular, DOS2 allows readers to reproduce many analyses from Design of Observational Studies.

Design of Observational Studies

Author : Paul R. Rosenbaum
Publisher : Springer Science & Business Media
Page : 382 pages
File Size : 47,9 Mb
Release : 2009-10-22
Category : Mathematics
ISBN : 9781441912138

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Design of Observational Studies by Paul R. Rosenbaum Pdf

An observational study is an empiric investigation of effects caused by treatments when randomized experimentation is unethical or infeasible. Observational studies are common in most fields that study the effects of treatments on people, including medicine, economics, epidemiology, education, psychology, political science and sociology. The quality and strength of evidence provided by an observational study is determined largely by its design. Design of Observational Studies is both an introduction to statistical inference in observational studies and a detailed discussion of the principles that guide the design of observational studies. Design of Observational Studies is divided into four parts. Chapters 2, 3, and 5 of Part I cover concisely, in about one hundred pages, many of the ideas discussed in Rosenbaum’s Observational Studies (also published by Springer) but in a less technical fashion. Part II discusses the practical aspects of using propensity scores and other tools to create a matched comparison that balances many covariates. Part II includes a chapter on matching in R. In Part III, the concept of design sensitivity is used to appraise the relative ability of competing designs to distinguish treatment effects from biases due to unmeasured covariates. Part IV discusses planning the analysis of an observational study, with particular reference to Sir Ronald Fisher’s striking advice for observational studies, "make your theories elaborate." The second edition of his book, Observational Studies, was published by Springer in 2002.

A First Course in Design and Analysis of Experiments

Author : Gary W. Oehlert
Publisher : W. H. Freeman
Page : 600 pages
File Size : 45,6 Mb
Release : 2000-01-19
Category : Mathematics
ISBN : 0716735105

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A First Course in Design and Analysis of Experiments by Gary W. Oehlert Pdf

Oehlert's text is suitable for either a service course for non-statistics graduate students or for statistics majors. Unlike most texts for the one-term grad/upper level course on experimental design, Oehlert's new book offers a superb balance of both analysis and design, presenting three practical themes to students: • when to use various designs • how to analyze the results • how to recognize various design options Also, unlike other older texts, the book is fully oriented toward the use of statistical software in analyzing experiments.

Design and Analysis of Experiments, Volume 1

Author : Klaus Hinkelmann,Oscar Kempthorne
Publisher : John Wiley & Sons
Page : 640 pages
File Size : 54,5 Mb
Release : 2007-12-04
Category : Mathematics
ISBN : 9780470191743

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Design and Analysis of Experiments, Volume 1 by Klaus Hinkelmann,Oscar Kempthorne Pdf

This user-friendly new edition reflects a modern and accessible approach to experimental design and analysis Design and Analysis of Experiments, Volume 1, Second Edition provides a general introduction to the philosophy, theory, and practice of designing scientific comparative experiments and also details the intricacies that are often encountered throughout the design and analysis processes. With the addition of extensive numerical examples and expanded treatment of key concepts, this book further addresses the needs of practitioners and successfully provides a solid understanding of the relationship between the quality of experimental design and the validity of conclusions. This Second Edition continues to provide the theoretical basis of the principles of experimental design in conjunction with the statistical framework within which to apply the fundamental concepts. The difference between experimental studies and observational studies is addressed, along with a discussion of the various components of experimental design: the error-control design, the treatment design, and the observation design. A series of error-control designs are presented based on fundamental design principles, such as randomization, local control (blocking), the Latin square principle, the split-unit principle, and the notion of factorial treatment structure. This book also emphasizes the practical aspects of designing and analyzing experiments and features: Increased coverage of the practical aspects of designing and analyzing experiments, complete with the steps needed to plan and construct an experiment A case study that explores the various types of interaction between both treatment and blocking factors, and numerical and graphical techniques are provided to analyze and interpret these interactions Discussion of the important distinctions between two types of blocking factors and their role in the process of drawing statistical inferences from an experiment A new chapter devoted entirely to repeated measures, highlighting its relationship to split-plot and split-block designs Numerical examples using SAS® to illustrate the analyses of data from various designs and to construct factorial designs that relate the results to the theoretical derivations Design and Analysis of Experiments, Volume 1, Second Edition is an ideal textbook for first-year graduate courses in experimental design and also serves as a practical, hands-on reference for statisticians and researchers across a wide array of subject areas, including biological sciences, engineering, medicine, pharmacology, psychology, and business.

Design and Analysis of Experiments

Author : Douglas C. Montgomery
Publisher : Wiley
Page : 0 pages
File Size : 51,7 Mb
Release : 2005
Category : Experimental design
ISBN : 0471661597

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Design and Analysis of Experiments by Douglas C. Montgomery Pdf

This bestselling professional reference has helped over 100,000 engineers and scientists with the success of their experiments. The new edition includes more software examples taken from the three most dominant programs in the field: Minitab, JMP, and SAS. Additional material has also been added in several chapters, including new developments in robust design and factorial designs. New examples and exercises are also presented to illustrate the use of designed experiments in service and transactional organizations. Engineers will be able to apply this information to improve the quality and efficiency of working systems.

Design and Analysis of Experiments in the Health Sciences

Author : Gerald van Belle,Kathleen F. Kerr
Publisher : John Wiley & Sons
Page : 256 pages
File Size : 53,6 Mb
Release : 2012-07-24
Category : Mathematics
ISBN : 9780470127278

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Design and Analysis of Experiments in the Health Sciences by Gerald van Belle,Kathleen F. Kerr Pdf

An accessible and practical approach to the design and analysis of experiments in the health sciences Design and Analysis of Experiments in the Health Sciences provides a balanced presentation of design and analysis issues relating to data in the health sciences and emphasizes new research areas, the crucial topic of clinical trials, and state-of-the- art applications. Advancing the idea that design drives analysis and analysis reveals the design, the book clearly explains how to apply design and analysis principles in animal, human, and laboratory experiments while illustrating topics with applications and examples from randomized clinical trials and the modern topic of microarrays. The authors outline the following five types of designs that form the basis of most experimental structures: Completely randomized designs Randomized block designs Factorial designs Multilevel experiments Repeated measures designs A related website features a wealth of data sets that are used throughout the book, allowing readers to work hands-on with the material. In addition, an extensive bibliography outlines additional resources for further study of the presented topics. Requiring only a basic background in statistics, Design and Analysis of Experiments in the Health Sciences is an excellent book for introductory courses on experimental design and analysis at the graduate level. The book also serves as a valuable resource for researchers in medicine, dentistry, nursing, epidemiology, statistical genetics, and public health.

The Design and Analysis of Computer Experiments

Author : Thomas J. Santner,Brian J. Williams,William I. Notz
Publisher : Springer
Page : 436 pages
File Size : 41,5 Mb
Release : 2019-01-08
Category : Mathematics
ISBN : 9781493988471

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The Design and Analysis of Computer Experiments by Thomas J. Santner,Brian J. Williams,William I. Notz Pdf

This book describes methods for designing and analyzing experiments that are conducted using a computer code, a computer experiment, and, when possible, a physical experiment. Computer experiments continue to increase in popularity as surrogates for and adjuncts to physical experiments. Since the publication of the first edition, there have been many methodological advances and software developments to implement these new methodologies. The computer experiments literature has emphasized the construction of algorithms for various data analysis tasks (design construction, prediction, sensitivity analysis, calibration among others), and the development of web-based repositories of designs for immediate application. While it is written at a level that is accessible to readers with Masters-level training in Statistics, the book is written in sufficient detail to be useful for practitioners and researchers. New to this revised and expanded edition: • An expanded presentation of basic material on computer experiments and Gaussian processes with additional simulations and examples • A new comparison of plug-in prediction methodologies for real-valued simulator output • An enlarged discussion of space-filling designs including Latin Hypercube designs (LHDs), near-orthogonal designs, and nonrectangular regions • A chapter length description of process-based designs for optimization, to improve good overall fit, quantile estimation, and Pareto optimization • A new chapter describing graphical and numerical sensitivity analysis tools • Substantial new material on calibration-based prediction and inference for calibration parameters • Lists of software that can be used to fit models discussed in the book to aid practitioners

The Theory of the Design of Experiments

Author : D.R. Cox,Nancy Reid
Publisher : CRC Press
Page : 337 pages
File Size : 50,7 Mb
Release : 2000-06-06
Category : Mathematics
ISBN : 9781420035834

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The Theory of the Design of Experiments by D.R. Cox,Nancy Reid Pdf

Why study the theory of experiment design? Although it can be useful to know about special designs for specific purposes, experience suggests that a particular design can rarely be used directly. It needs adaptation to accommodate the circumstances of the experiment. Successful designs depend upon adapting general theoretical principles to the spec

Experiments in Public Management Research

Author : Oliver James,Sebastian R. Jilke,Gregg G. Van Ryzin
Publisher : Cambridge University Press
Page : 549 pages
File Size : 40,9 Mb
Release : 2017-07-27
Category : Business & Economics
ISBN : 9781107162051

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Experiments in Public Management Research by Oliver James,Sebastian R. Jilke,Gregg G. Van Ryzin Pdf

An overview of experimental research and methods in public management, and their impact on theory, research practices and substantive knowledge.

Designing Online Experiments for the Social Sciences

Author : Giuseppe Veltri
Publisher : SAGE Publications Limited
Page : 152 pages
File Size : 53,5 Mb
Release : 2023-04-13
Category : Social Science
ISBN : 9781529788822

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Designing Online Experiments for the Social Sciences by Giuseppe Veltri Pdf

This book guides you through designing and implementing an online experiment in social science research in a clear and straightforward manner. At an approachable pace, it covers foundational principles of good experimental design before setting out best practice for how to design and conduct web experiments, taking into account the specific methodological challenges of working online with digital tools. The book: Offers practical advice for approaching every stage of the research process Breaks real-world examples into easy to follow steps Focuses on how to make good decisions and choose the right design for your research project This pragmatic guide helps beginner researchers get started with online experiments confidently. It is supported by online resources such as case studies which allow you to see the concepts in practice, and weblinks to tools and resources to aid you.

Observational Studies

Author : Paul R. Rosenbaum
Publisher : Springer Science & Business Media
Page : 244 pages
File Size : 47,8 Mb
Release : 2013-06-29
Category : Mathematics
ISBN : 9781475724431

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Observational Studies by Paul R. Rosenbaum Pdf

An observational study is an empirical investigation of the effects of treatments, policies, or exposures. It differes from an experiment in that the investigator cannot control the assignments of treatments to subjects. Scientists across a wide range of disciplines undertake such studies, and the aim of this book is to provide a sound statistical account of the principles and methods for the design and analysis of observational studies. Readers are assumed to have a working knowledge of basic probability and statistics, but otherwise the account is reasonably self-contained. Throughout there are extended discussions of actual observational studies to illustrate the ideas discussed. These are drawn from topics as diverse as smoking and lung cancer, lead in children, nuclear weapons testing, and placement programs for students. As a result, many researchers involved in observational studes will find this an invaluable companion to their work.

Optimal Experimental Design with R

Author : Dieter Rasch,Jurgen Pilz,L.R. Verdooren,Albrecht Gebhardt
Publisher : CRC Press
Page : 345 pages
File Size : 52,6 Mb
Release : 2011-05-18
Category : Mathematics
ISBN : 9781439816981

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Optimal Experimental Design with R by Dieter Rasch,Jurgen Pilz,L.R. Verdooren,Albrecht Gebhardt Pdf

Experimental design is often overlooked in the literature of applied and mathematical statistics: statistics is taught and understood as merely a collection of methods for analyzing data. Consequently, experimenters seldom think about optimal design, including prerequisites such as the necessary sample size needed for a precise answer for an experi