Determination And Production Of An Optimal Neutron Energy Spectrum For Boron Neutron Capture Therapy

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Spectral Tailoring for Boron Neutron Capture Therapy

Author : Victor Alexander Nievaart
Publisher : IOS Press
Page : 144 pages
File Size : 48,5 Mb
Release : 2007
Category : Medical
ISBN : 1586037625

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Spectral Tailoring for Boron Neutron Capture Therapy by Victor Alexander Nievaart Pdf

Since the first clinical trials on Boron Neutron Capture Therapy in the 1950s, BNCT research has been mainly focussed on the treatment of (deep-seated) brain tumours, in particular, glioblastoma multiforme. Promising work to treat other cancers at other locations and even other diseases are in progress. Therefore, the chemists, medical doctors, physicists and biologists involved in BNCT are not only continuing to investigate and improve the (brain) clinical results, but are also investigating the new applications in BNCT. The work presented in this thesis is in the field of physics and deals, from three different viewpoints, with obtaining the optimal source neutron energy to optimise BNCT. The optimal source neutron energy is defined such as to obtain as many as possible (n, a)-absorptions due to 10B in the tumours and as low as possible total neutron dose in the healthy tissues and organs at risk

Neutron Beam Design, Development, and Performance for Neutron Capture Therapy

Author : Otto K. Harling,John a. Bernard,Robert C. Zamenhof
Publisher : Springer Science & Business Media
Page : 340 pages
File Size : 40,8 Mb
Release : 2013-03-08
Category : Medical
ISBN : 9781468458022

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Neutron Beam Design, Development, and Performance for Neutron Capture Therapy by Otto K. Harling,John a. Bernard,Robert C. Zamenhof Pdf

For this Workshop, the organizers have attempted to invite experts from all known centers which are engaged in neutron beam development for neutron capture therapy. The Workshop was designed around a series of nineteen invited papers which dealt with neutron source design and development and beam characterization and performance. Emphasis was placed on epithermal beams because they offer clinical advantages and are more challenging to implement than thermal beams. Fission reactor sources were the basis for the majority of the papers; however three papers dealt with accelerator neutron sources. An additional three invited papers provided a summary of clinical results of Ncr therapy in Japan between 1968 and 1989 and overviews of clinical considerations for neutron capture therapy and of the status of tumor targeting chemical agents for Ncr. Five contributed poster papers dealing with NCT beam design and performance were also presented. A rapporteurs' paper was prepared after the Workshop to attempt to summarize the major aspects, issues, and conclusions which resulted from this Workshop. Many people contributed to both the smooth functioning of the Workshop and to the preparation of these proceedings. Special thanks are reserved for Ms. Dorothy K.

Neutron Generators for Analytical Purposes

Author : International Atomic Energy Agency
Publisher : IAEA Radiation Technology Repo
Page : 145 pages
File Size : 51,7 Mb
Release : 2012
Category : Science
ISBN : 9201251106

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Neutron Generators for Analytical Purposes by International Atomic Energy Agency Pdf

This publication addresses recent developments in neutron generator (NG) technology. It presents information on compact instruments with high neutron yield to be used for neutron activation analysis (NAA) and prompt gamma neutron activation analysis in combination with high count rate spectrometers. Traditional NGs have been shown to be effective for applications including borehole logging, homeland security, nuclear medicine and the on-line analysis of aluminium, coal and cement. Pulsed fast thermal neutron analysis, as well as tagged and timed neutron analysis, are additional techniques which can be applied using NG. Furthermore, NG can effectively be used for elemental analysis and is also effective for analysis of hidden materials by neutron radiography. Useful guidelines for developing NG based research laboratories are also provided in this publication.

Neutron Capture Therapy

Author : Wolfgang A.G. Sauerwein,Andrea Wittig,Raymond Moss,Yoshinobu Nakagawa
Publisher : Springer Science & Business Media
Page : 545 pages
File Size : 45,8 Mb
Release : 2012-11-05
Category : Medical
ISBN : 9783642313349

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Neutron Capture Therapy by Wolfgang A.G. Sauerwein,Andrea Wittig,Raymond Moss,Yoshinobu Nakagawa Pdf

Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter, which in principle allows for tumor cell-selective high-LET particle radiotherapy. This book provides a comprehensive summary of the progress made in NCT in recent years. Individual sections cover all important aspects, including neutron sources, boron chemistry, drugs for NCT, dosimetry, and radiation biology. The use of NCT in a variety of malignancies and also some non-malignant diseases is extensively discussed. NCT is clearly shown to be a promising modality at the threshold of wider clinical application. All of the chapters are written by experienced specialists in language that will be readily understood by all participating disciplines.

Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine

Author : H. Zaidi,G Sgouros
Publisher : CRC Press
Page : 441 pages
File Size : 53,7 Mb
Release : 2002-09-01
Category : Medical
ISBN : 9781000687682

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Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine by H. Zaidi,G Sgouros Pdf

Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine examines the applications of Monte Carlo (MC) calculations in therapeutic nuclear medicine, from basic principles to computer implementations of software packages and their applications in radiation dosimetry and treatment planning. With chapters written by recognized authorit

Neutrons in Research and Industry

Author : George Vourvopoulos
Publisher : SPIE-International Society for Optical Engineering
Page : 666 pages
File Size : 51,9 Mb
Release : 1997
Category : Science
ISBN : UOM:39015041077929

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Neutrons in Research and Industry by George Vourvopoulos Pdf

Dissertation Abstracts International

Author : Anonim
Publisher : Unknown
Page : 886 pages
File Size : 44,5 Mb
Release : 2006
Category : Dissertations, Academic
ISBN : STANFORD:36105123430030

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Dissertation Abstracts International by Anonim Pdf

Nuclear Science Abstracts

Author : Anonim
Publisher : Unknown
Page : 852 pages
File Size : 51,7 Mb
Release : 1974
Category : Nuclear energy
ISBN : UOM:39015023546214

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Nuclear Science Abstracts by Anonim Pdf

Energy Research Abstracts

Author : Anonim
Publisher : Unknown
Page : 490 pages
File Size : 49,8 Mb
Release : 1993
Category : Power resources
ISBN : PSU:000052606168

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Energy Research Abstracts by Anonim Pdf

Intense Neutron Sources

Author : U.S. Atomic Energy Commission
Publisher : Unknown
Page : 856 pages
File Size : 48,9 Mb
Release : 1966
Category : Neutron sources
ISBN : UOM:39015086510404

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Intense Neutron Sources by U.S. Atomic Energy Commission Pdf

Cumulated Index Medicus

Author : Anonim
Publisher : Unknown
Page : 1808 pages
File Size : 46,9 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864948

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Cumulated Index Medicus by Anonim Pdf

Research Reactor Application for Materials Under High Neutron Fluence

Author : Anonim
Publisher : Unknown
Page : 185 pages
File Size : 44,6 Mb
Release : 2011
Category : Sewage
ISBN : OCLC:1132100388

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Research Reactor Application for Materials Under High Neutron Fluence by Anonim Pdf

"This publication presents the proceedings of a technical meeting on research reactor application for materials under high neutron fluence. The overall objective of the meeting was to enhance research reactor utilization in Member States for practical applications such as isotope production, neutron radiography, neutron beam research, and material characterization and testing consistent with the reactor's research function. In addition, the meeting participants focused on the specific applications of research reactors in irradiation of materials at high neutron fluence, as well as integration issues. The publication will serve as a tool to maintain existing knowledge available in Member States and is expected to contribute to the initiation and development of new research programmes related to the testing of structural materials needed for innovative reactor systems"--Publisher's description.

Boron Neutron Capture Therapy

Author : Detlef Gabel,Raymond Moss
Publisher : Springer Science & Business Media
Page : 274 pages
File Size : 41,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461534082

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Boron Neutron Capture Therapy by Detlef Gabel,Raymond Moss Pdf

The European Collaboration on Boron Neutron Capture Therapy (BNCT), conceived in 1987 and successful in 1989 in gaining financial support as a Concerted Action through the Medical and Health Research Programme of the Commission ofthe European Communities (CEC) in Brussels, considered it an opportune moment to hold its annual Plenary Meeting on 18-20 Septem ber 1991 as an International Workshop entitled "Towards Clinical Trials of Glioma with BNCT". The background to this consideration was influenced by the world-wide resurgence ofinterest in NCT over the last 2 decades and by the exemplifica tions at the Fourth International Symposium on Neutron Capture Therapy for Cancer held in Sydney in December 1990, where it was strongly indicated that within the next 2 years clinical trials would be started both in Europe and the United States. In particular at the High Flux Reactor of the Joint Research Centre of the CEC at Petten in The Netherlands, an epithermal neutron beam designed and installed in the summer of 1990 recently became operable at full reactor power. An extensive series ofexperiments, including the nuclear and radiobiological characterisation of the beam and a healthy tissue tolerance study on canines has started and has the aim to define the preconditions for clinical trials onpatients with Grade III/IV glioma. However, as with any other new therapy modality, it must be demon strated that BNCT is safe for the patient and has a reasonable chance of being an effective therapy.

Handbook of Radioactivity Analysis

Author : Michael F. L'Annunziata
Publisher : Academic Press
Page : 1110 pages
File Size : 45,5 Mb
Release : 2020-03-03
Category : Science
ISBN : 9780128143988

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Handbook of Radioactivity Analysis by Michael F. L'Annunziata Pdf

Handbook of Radioactivity Analysis: Radiation Physics and Detectors, Volume One, and Radioanalytical Applications, Volume Two, Fourth Edition, is an authoritative reference on the principles, practical techniques and procedures for the accurate measurement of radioactivity - everything from the very low levels encountered in the environment, to higher levels measured in radioisotope research, clinical laboratories, biological sciences, radionuclide standardization, nuclear medicine, nuclear power, and fuel cycle facilities, and in the implementation of nuclear forensic analysis and nuclear safeguards. It includes sample preparation techniques for all types of matrices found in the environment, including soil, water, air, plant matter and animal tissue, and surface swipes. Users will find a detailed discussion of our current understanding of the atomic nucleus, nuclear stability and decay, nuclear radiation, and the interaction of radiation with matter relating to the best methods for radionuclide detection and measurement. Spans two volumes, Radiation Physics and Detectors and Radioanalytical Applications Includes a much-expanded treatment of calculations required in the measurement of radionuclide decay, energy of decay, nuclear reactions, radiation attenuation, nuclear recoil, cosmic radiation, and synchrotron radiation Includes the latest advances in liquid and solid scintillation analysis, alpha- and gamma spectrometry, mass spectrometric analysis, gas ionization and nuclear track analysis, and neutron detection and measurement Covers high-sample-throughput microplate techniques and multi-detector assay methods