Dieseases Of The Wistar Rat

Author : Mary J Tucker
Publisher : CRC Press
Page : 269 pages
File Size : 43,7 Mb
Release : 1997-05-21
Category : Medical
ISBN : 9780748405213

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Dieseases of the Wistar Rat by Mary J Tucker Pdf

This text provides a complete account of this particular rat strain. The book includes extensive data on reproductive indices, congenital abnormalities, growth, clinical signs, mortality, organ weights and chemical pathology. The data are derived from around 9000 control animals used in toxicology studies of two weeks to two years duration, completed between 1960 and 1992, and include 24 two-year studies and one life-span study of a 51 month duration. These extended periods of study have shown that many diseases are seen more frequently in later years.; Diseases are dealt with by body system and include clinical signs, macroscopic features and histopathology illustrations of the important or unusual diseases. Incidence levels are provided for all diseases and these are compared with published data for other rat strains.

Author : Henry J. Baker,James Russell Lindsey,Steven H. Weisbroth
Publisher : Unknown
Page : 464 pages
File Size : 54,6 Mb
Release : 1979
Category : Medical
ISBN : 0120749017

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The Laboratory Rat by Henry J. Baker,James Russell Lindsey,Steven H. Weisbroth Pdf

Author : Mark A. Suckow,Steven H. Weisbroth,Craig L. Franklin
Publisher : Elsevier
Page : 928 pages
File Size : 40,5 Mb
Release : 2005-12-20
Category : Science
ISBN : 9780080454320

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The Laboratory Rat by Mark A. Suckow,Steven H. Weisbroth,Craig L. Franklin Pdf

The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research. At least 50% new information than first edition Includes topics on rat genetics and genomics, occupational health, and experimental models The premier source of information on the laboratory rat

Author : National Research Council,Board on Agriculture,Committee on Animal Nutrition,Subcommittee on Laboratory Animal Nutrition
Publisher : National Academies Press
Page : 188 pages
File Size : 42,6 Mb
Release : 1995-02-01
Category : Science
ISBN : 9780309051262

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Nutrient Requirements of Laboratory Animals, by National Research Council,Board on Agriculture,Committee on Animal Nutrition,Subcommittee on Laboratory Animal Nutrition Pdf

In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.

Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals
Publisher : National Academies Press
Page : 246 pages
File Size : 47,6 Mb
Release : 2011-01-27
Category : Science
ISBN : 9780309154000

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Guide for the Care and Use of Laboratory Animals by National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals Pdf

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Author : Marie Kubiak
Publisher : John Wiley & Sons
Page : 524 pages
File Size : 41,6 Mb
Release : 2020-08-24
Category : Medical
ISBN : 9781119389958

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Handbook of Exotic Pet Medicine by Marie Kubiak Pdf

Easy-to-use, comprehensive reference covering the less common species encountered in general veterinary practice Handbook of Exotic Pet Medicine provides easy-to-access, detailed information on a wide variety of exotic species that can be encountered in general veterinary practice. Offering excellent coverage of topics such as basic techniques, preventative health measures, and a formulary for each species, each chapter uses the same easy-to-follow format so that users can find information quickly while working in the clinic. Presented in full colour, with over 400 photographs, the book gives small animal practitioners the confidence to handle and treat more familiar pets such as budgerigars, African grey parrots, bearded dragons, corn snakes, tortoises, pygmy hedgehogs, hamsters and rats. Other species that may be presented less frequently including skunks, marmosets, sugar gliders, koi carp, chameleons and terrapins are also covered in detail to enable clinicians to quickly access relevant information. Provides comprehensive coverage of many exotic pet species that veterinarians may encounter in general practice situations Presents evidence-based discussions of topics including biological parameters, husbandry, clinical evaluation, hospitalization requirements, common medical and surgical conditions, radiographic imaging, and more The Handbook of Exotic Pet Medicine is an ideal one-stop reference for the busy general practitioner seeing the occasional exotic animal, veterinary surgeons with an established exotic animal caseload, veterinary students and veterinary nurses wishing to further their knowledge.

Author : Andrew W. Suttie,Joel R. Leininger,Alys E. Bradley
Publisher : Academic Press
Page : 748 pages
File Size : 51,7 Mb
Release : 2017-12-18
Category : Medical
ISBN : 9780123914897

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Boorman's Pathology of the Rat by Andrew W. Suttie,Joel R. Leininger,Alys E. Bradley Pdf

Boorman’s Pathology of the Rat: Reference and Atlas, Second Edition, continues its history as the most comprehensive pathology reference on rat strains for researchers across science and medicine using rat models in the laboratory. It offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry. In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. With updated references and photographs, as well as coverage of all rat strains, this book is not only the standard in the field, but also an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to the promulgation of meaningful regulations. Contains full, four color photographs from the NTP archive and database and coverage of all rat strains Provides an organ-by-organ and system-by-system approach that presents standard diagnostic criteria and basic content on histology and histological changes Includes comprehensive and detailed background incidence data Presents detailed descriptive content regarding changes in rat models during research

Author : Elizabeth Fiona McInnes
Publisher : Elsevier Health Sciences
Page : 256 pages
File Size : 55,8 Mb
Release : 2011-10-24
Category : Medical
ISBN : 9780702049248

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Background Lesions in Laboratory Animals E-Book by Elizabeth Fiona McInnes Pdf

Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas. over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals a chapter on common artifacts that may be observed in histological glass slides extensive references to each lesion described aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies

Author : Jose V. Castell,Maria Jose Gmez-Lechn
Publisher : Elsevier
Page : 483 pages
File Size : 54,5 Mb
Release : 1996-10-04
Category : Medical
ISBN : 9780080534602

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In Vitro Methods in Pharmaceutical Research by Jose V. Castell,Maria Jose Gmez-Lechn Pdf

In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available. It is a welcome addition to the literature at a time when interest is growing in cellular in vitro models for toxicology and pharmacology studies. Meets the continuing demand for information in this field Compares In Vitro techniques with other methods Describes cell-culture methods used to investigate toxicity in cells derived from different organs Includes contributions by leading experts in the field

Author : Burek
Publisher : CRC Press
Page : 240 pages
File Size : 48,5 Mb
Release : 2018-01-10
Category : Medical
ISBN : 9781351092333

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Pathology Of Aging Rats by Burek Pdf

This study presents age-associated pathologic findings in aging rats that had been maintained under similar well-controlled laboratory conditions. The aim of the study was to evaluate two rat strains and their F1, hybrid.

Author : Mark A. Suckow,Kay Stewart
Publisher : Academic Press
Page : 286 pages
File Size : 41,9 Mb
Release : 2016-11-16
Category : Medical
ISBN : 9780128023662

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Principles of Animal Research for Graduate and Undergraduate Students by Mark A. Suckow,Kay Stewart Pdf

Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all aspects of the research experience, including the research and development of a thesis, model selection, experimental design, IACUC protocol preparation, and animal husbandry and technical procedural needs, the book is a necessary addition to every student, technician, and researcher’s education. Provides background material for students to understand the broader backdrop against which animal research is undertaken Includes ethical and regulatory information Covers commonly used animal models and the process to choose a model for biomedical research

Author : Milton Jay Greenman,Fannie Louise Duhring
Publisher : Unknown
Page : 140 pages
File Size : 47,8 Mb
Release : 1931
Category : Rats
ISBN : WISC:89043233329

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Breeding and Care of the Albino Rat for Research Purposes by Milton Jay Greenman,Fannie Louise Duhring Pdf

Author : Thomas Carlyle Jones,Ulrich Mohr,Ronald Duncan Hunt
Publisher : Springer Science & Business Media
Page : 994 pages
File Size : 46,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642725500

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Genital System by Thomas Carlyle Jones,Ulrich Mohr,Ronald Duncan Hunt Pdf

The International Life Sciences Institute (ILSI) was estab lished to stimulate and support scientific research and edu cational programs in nutrition, toxicology, and food safe ty; and to encourage cooperation in these programs among scientists from universities, industry, and government in order to facilitate the resolution of health and safety issues. The officers and trustees of ILSI believe that questions re garding health and safety are best resolved when govern ment and industry rely on scientific investigations, analy ses, and reviews by independent experts. This process is furthered by the examination and discussion of issues on an international basis. ILSI is pleased to sponsor this set of monographs on the pathology of laboratory animals. This project collectively brings together the most comprehensive information on non-neoplastic and neoplastic lesions that occur in com monly used laboratory animals. The international compo sition of the authors, editors, and editorial board who have contributed to these monographs strengthens our expecta tions that understanding and cooperation will be strength ened worldwide through this series.

Author : Trenton R Schoeb,Kathryn A Eaton
Publisher : Academic Press
Page : 428 pages
File Size : 47,7 Mb
Release : 2017-08-11
Category : Medical
ISBN : 9780128045831

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Gnotobiotics by Trenton R Schoeb,Kathryn A Eaton Pdf

Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource. Reviews and defines gnotobiotic animal species Analyzes microbiota in numerous contexts Presents detailed coverage of the protocols and operation of a gnotobiotic facility

Author : Xijun Wang,Aihua Zhang,Hui Sun
Publisher : Academic Press
Page : 378 pages
File Size : 51,6 Mb
Release : 2016-12-27
Category : Medical
ISBN : 9780128111482

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Serum Pharmacochemistry of Traditional Chinese Medicine by Xijun Wang,Aihua Zhang,Hui Sun Pdf

Serum Pharmacochemistry of Traditional Chinese Medicine: Technologies, Strategies and Applications provides a valuable and indispensable guide on the latest methods, research advances, and applications in this area. Chapters offer cutting-edge information on pharmacokinetics and pharmacodynamics, analytical chemistry, traditional medicine, natural products, bioinformatics, new technologies, therapeutic applications, and more. For researchers and students in academia and industry, this book provides a hands-on description of experimental techniques, along with beneficial guidelines to help advance research in the fields of Traditional Chinese Medicine and drug development. Provides a valuable guide for practitioners of serum pharmacochemistry of Traditional Chinese Medicine, along with insights to its current use and future applications Edited and written by leading scientists at the forefront of this research Presents well written chapters that include an introduction, description of the method, and identification of chemical constituents, with applications and references to the latest research and literature