Drug Interactions

Author : Ashraf Mozayani,Lionel Raymon
Publisher : Springer Science & Business Media
Page : 662 pages
File Size : 50,9 Mb
Release : 2003-10-15
Category : Medical
ISBN : 9781592596546

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Handbook of Drug Interactions by Ashraf Mozayani,Lionel Raymon Pdf

A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.

Author : A. David Rodrigues
Publisher : CRC Press
Page : 769 pages
File Size : 51,9 Mb
Release : 2019-01-03
Category : Medical
ISBN : 9780849375941

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Drug-Drug Interactions by A. David Rodrigues Pdf

Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives.Thoroughly updated, this second edition reflects the significant advances and includes extensive new material on:key interplay between transporters and enzymes

Author : Gary H. Wynn,Jessica R. Oesterheld,Kelly L. Cozza,Scott C. Armstrong
Publisher : American Psychiatric Pub
Page : 608 pages
File Size : 41,6 Mb
Release : 2009-06-03
Category : Medical
ISBN : 9781585628926

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Clinical Manual of Drug Interaction Principles for Medical Practice by Gary H. Wynn,Jessica R. Oesterheld,Kelly L. Cozza,Scott C. Armstrong Pdf

Drug interactions have become a significant iatrogenic complication, with as many as 5% of hospitalizations and 7,000 deaths annually attributable to drug-drug interactions in the United States. There are several reasons these numbers have increased. First, many new medications have been brought to market in recent years. Second, advances in medical care have resulted in increased longevity and more elderly patients than ever before -- patients who are more likely to be following polypharmacy regimens. Population patterns in the U.S. have amplified this trend, with aging baby boomers swelling the patient pool and demanding treatment with medications advertised on television and in print. Fortunately, drug interactions can be prevented with access to current, comprehensive, reliable information, and the Clinical Manual of Drug Interaction Principles for Medical Practice provides just that in a user-friendly format psychiatry clinicians (including residents and nurses) and forensics experts will find indispensable. With this new edition, the book has evolved from "Concise Guide" to "Clinical Manual" and offers the expanded coverage and features healthcare providers need to keep up with this critical field. The book is well organized, with major sections on metabolism; cytochrome P450 enzymes; drug interactions by medical specialty; and practical matters, such as the medicolegal implications of drug-drug interactions and how to retrieve and review the literature. In the section on P450 enzymes, each chapter addresses what the individual enzyme does and where, its polymorphisms, and drugs that inhibit or induce activity. Each chapter also includes extensive references and study cases to help the reader understand and contextualize the information. A number of additional features enhance the book's scope and utility: The book boasts the very latest information in the area of drug metabolism, transport, and interaction. The chapter on P-glycoprotein (a drug transporter) was expanded from the last edition to include a broader array of transport mechanisms. The highest ethical standard was adhered to in the development of this volume, which was not supported in any way by pharmaceutical makers or distributors. All eight contributors to this excellent resource are experts in the fields they have addressed, and clinicians can trust that the information contained in the Manual reflects the very latest research. This exceptionally practical manual is essential to maintaining the highest standard of care.

Author : Francis J. Brinker
Publisher : Unknown
Page : 272 pages
File Size : 50,6 Mb
Release : 1998
Category : Drug interactions
ISBN : UOM:39015047500312

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Herb Contraindications and Drug Interactions by Francis J. Brinker Pdf

Author : Mitchell Bebel Stargrove,Jonathan Treasure,Dwight L. McKee
Publisher : Elsevier Health Sciences
Page : 961 pages
File Size : 52,8 Mb
Release : 2007-12-06
Category : Medical
ISBN : 9780323029643

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Herb, Nutrient, and Drug Interactions by Mitchell Bebel Stargrove,Jonathan Treasure,Dwight L. McKee Pdf

Presenting detailed, evidence-based coverage of the most commonly encountered therapeutic agents in modern clinical practice, this resource is designed to help you safely and effectively integrate herbal, nutrient, and drug therapy for your patients or clients. Combining pharmaceuticals with herbs or supplements may complement or interfere with a drug's therapeutic action or may increase adverse effects. Additionally, drug-induced depletion of nutrients can occur. Comprehensive clinical data, quick-reference features, and the insight and expertise of trusted authorities help you gain a confident understanding of how herbal remedies and nutritional supplements interact with pharmaceuticals and develop safe, individualized treatment strategies for your patients. More than 60 comprehensive monographs of herb-drug and nutrient-drug interactions cover the most commonly used herbs and nutrients in health-related practice and help you coordinate safe, reliable therapy. Each herb and nutrient monograph features summary tables and concise, practical suggestions that provide quick and easy reference and complement the systematic review and in-depth analysis. References included on the bound-in CD provide high-quality, evidence-based support. Unique icons throughout the text differentiate interactions, evidence, and clinical significance. Up-to-date information keeps you current with the latest developments in pharmacology, nutrition, phytotherapy, biochemistry, genomics, oncology, hematology, naturopathic medicine, Chinese medicine, and other fields. A diverse team of authoritative experts lends valuable, trans-disciplinary insight.

Author : World Health Organization. Department of Mental Health and Substance Abuse,World Health Organization
Publisher : World Health Organization
Page : 133 pages
File Size : 51,7 Mb
Release : 2009
Category : Medical
ISBN : 9789241547543

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Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence by World Health Organization. Department of Mental Health and Substance Abuse,World Health Organization Pdf

"These guidelines were produced by the World Health Organization (WHO), Department of Mental Health and Substance Abuse, in collaboration with the United Nations Office on Drugs and Crime (UNODC) a Guidelines Development Group of technical experts, and in consultation with the International Narcotics Control Board (INCB) secretariat and other WHO departments. WHO also wishes to acknowledge the financial contribution of UNODC and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to this project. " - p. iv

Author : Centers for Disease Control and Prevention CDC
Publisher : Oxford University Press
Page : 672 pages
File Size : 51,6 Mb
Release : 2017-04-17
Category : Medical
ISBN : 9780190628635

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CDC Yellow Book 2018: Health Information for International Travel by Centers for Disease Control and Prevention CDC Pdf

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Author : Catherine Marcucci,Michael P. Hutchens,Erica D. Wittwer,Toby N. Weingarten,Juraj Sprung,Wayne T. Nicholson,Kirk Lalwani,David G. Metro,Randal O. Dull,Christopher E. Swide,F. Jacob Seagull,Jeffrey R. Kirsch,Neil B. Sandson
Publisher : Springer
Page : 1016 pages
File Size : 41,8 Mb
Release : 2015-09-15
Category : Medical
ISBN : 9781461474951

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A Case Approach to Perioperative Drug-Drug Interactions by Catherine Marcucci,Michael P. Hutchens,Erica D. Wittwer,Toby N. Weingarten,Juraj Sprung,Wayne T. Nicholson,Kirk Lalwani,David G. Metro,Randal O. Dull,Christopher E. Swide,F. Jacob Seagull,Jeffrey R. Kirsch,Neil B. Sandson Pdf

The occurrence of deleterious or even fatal drug-drug interactions (DDIs) in the perioperative period is no longer a theoretical concern but a harrowing reality. A Case Approach to Perioperative Drug-Drug Interactions addresses the complex realm of pharmacokinetic drug interactions in an easy-to-read volume that functions as both a comprehensive clinical reference and a casebook. The book presents a summary of the core concepts of drug interactions; an organized, annotated presentation of the drug interactions most relevant to the perioperative clinician; and approximately 200 case scenarios that highlight specific drug interactions. This book fills a real void in the clinical literature and is invaluable to anesthesiologists and surgeons, as well as trainees in both specialties; intensive care staff, including physicians, physician’s assistants, and nurses; and nurse practitioners who staff preoperative evaluation clinics.

Author : Kelly Anne Meckling
Publisher : CRC Press
Page : 352 pages
File Size : 47,6 Mb
Release : 2006-06-23
Category : Medical
ISBN : 9781420019131

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Nutrient-Drug Interactions by Kelly Anne Meckling Pdf

Current research has given us a more complete understanding of how the chemicals in foods and herbs interact with natural and synthetic drugs. In some cases a single food or supplement can profoundly increase or decrease the toxicity and/or efficacy of a single drug. Although it is standard practice to examine the effects of food consumption on the

Author : Patrick F. D'Arcy,James C. McElnay,Peter G. Welling
Publisher : Springer Science & Business Media
Page : 363 pages
File Size : 40,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642610158

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Mechanisms of Drug Interactions by Patrick F. D'Arcy,James C. McElnay,Peter G. Welling Pdf

Over the years a number of excellent books have classified and detailed drug drug interactions into their respective categories, e.g. interactions at plasma protein binding sites; those altering intestinal absorption or bioavailability; those involving hepatic metabolising enzymes; those involving competition or antagonism for receptor sites, and drug interactions modifying excretory mechanisms. Such books have presented extensive tables of interactions and their management. Although of considerable value to clinicians, such publica tions have not, however, been so expressive about the individual mechanisms that underlie these interactions. It is within this sphere of "mechanisms" that this present volume specialises. It deals with mechanisms of in vitro and in vivo, drug-drug, drug food and drug-herbals interactions and those that cause drugs to interfere with diagnostic laboratory tests. We believe that an explanation of the mechanisms of such interactions will enable practitioners to understand more fully the nature of the interactions and thus enable them to manage better their clinical outcome. If mechanisms of interactions are better understood, then it may be pos sible for the researcher to develop meaningful animal/biochemical/tissue cul ture or physicochemical models to which new molecules could be exposed during their development stages. The present position, which largely relies on patients experiencing adverse interactions before they can be established or documented, can hardly be regarded as satisfactory. This present volume is classified into two major parts; firstly, pharmacoki netic drug interactions and, secondly, pharmacodynamic drug interactions.

Author : Beverly McCabe-Sellers,Eric H. Frankel,Jonathan J. Wolfe
Publisher : CRC Press
Page : 937 pages
File Size : 53,6 Mb
Release : 2003-04-29
Category : Medical
ISBN : 9781135504571

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Handbook of Food-Drug Interactions by Beverly McCabe-Sellers,Eric H. Frankel,Jonathan J. Wolfe Pdf

With contributions from the fields of pharmacy, dietetics, and medicine, Handbook of Food-Drug Interactions serves as an interdisciplinary guide to the prevention and correction of negative food-drug interactions. Rather than simply list potential food-drug interactions, this book provides explanations and gives specific recommendations based on th

Author : Domenic A. Ciraulo
Publisher : Lippincott Williams & Wilkins
Page : 474 pages
File Size : 41,5 Mb
Release : 2006
Category : Medical
ISBN : 0781748178

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Drug Interactions in Psychiatry by Domenic A. Ciraulo Pdf

Thoroughly updated for its Third Edition, this handbook provides complete, current, and easily accessible information on how psychotropic drugs interact with one another and with compounds used to treat non-psychiatric medical conditions. The book is organized for rapid reference, includes numerous tables, and offers guidelines for managing adverse effects. The Third Edition includes an adverse drug effects table in the appendix section, tables on receptor binding and dosing, and the latest information on drugs of abuse and chemical dependence. This edition also includes drug-food interactions for each drug category and interactions of psychotropic drugs with HIV medications.

Author : Joe Graedon,Teresa Graedon
Publisher : Macmillan
Page : 532 pages
File Size : 55,6 Mb
Release : 1999-02-15
Category : Family & Relationships
ISBN : 0312968264

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Dangerous Drug Interactions by Joe Graedon,Teresa Graedon Pdf

In straightforward text, and with dozens of easy-to-read, easy-to-understand charts and tables, the authors cut through drug company fine print to give consumers vital information on the prescription drugs and over-the-counter remedies that react in deadly ways--with each other, foods, vitamins, minerals, herbs, and with alcohol. Martin's Press.

Author : Karen Baxter
Publisher : Unknown
Page : 1792 pages
File Size : 46,7 Mb
Release : 2010
Category : Medical
ISBN : 0853699143

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Stockley's Drug Interactions by Karen Baxter Pdf

Stockley's Drug Interactions, now fully revised and revalidated, remains the world's most comprehensive and authoritative reference book on drug interactions and provides the busy healthcare professional with quick and easy access to clinically relevant, evaluated and evidence-based information on drug interactions. Contains detailed yet concise monographs: covers interactions between therapeutic drugs, proprietary medicines, herbal medicines, foods, drinks, pesticides and drugs of abuse; based on published sources and fully referenced; provides comprehensive details of the clinical evidence for the interactions under discussion, an assessment of their clinical importance and gives clear guidance on how to manage the interaction in practice; contains over 3,400 monographs; New drugs launched in the last two years added - including drugs such as fesoterodine, several monoclonal antibodies, new antidiabetics (e.g. sitagliptin) new antineoplastics (e.g. dasatinib) and new immunosuppressants (e.g. temsirolimus); updated information on seasonal flu vaccines and antivirals, including all available information on possible interactions with concurrent medication; increased commentary on the involvement of newer mechanisms in drug interactions, such as drug transporter proteins, and other genetic factors that affect the ability of individuals to metabolise medicines.

Author : Honghui Zhou,Bernd Meibohm
Publisher : John Wiley & Sons
Page : 272 pages
File Size : 42,8 Mb
Release : 2013-05-10
Category : Medical
ISBN : 9781118630211

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Drug-Drug Interactions for Therapeutic Biologics by Honghui Zhou,Bernd Meibohm Pdf

Strategize, plan, and execute comprehensive drug-drug interaction assessments for therapeutic biologics Offering both theory and practical guidance, this book fully explores drug-drug interaction assessments for therapeutic biologics during the drug development process. It draws together and analyzes all the latest findings and practices in order to present our current understanding of the topic and point the way to new research. Case studies and examples, coupled with expert advice, enable readers to better understand the complex mechanisms of biologic drug-drug interactions. Drug-Drug Interactions for Therapeutic Biologics features contributions from leading international experts in all areas of therapeutic biologics drug development and drug-drug interactions. The authors' contributions reflect a thorough review and analysis of the literature as well as their own firsthand laboratory experience. Coverage includes such essential topics as: Drug-drug interaction risks in combination with small molecules and other biologics Pharmacokinetic and pharmacodynamic drug-drug interactions In vitro methods for drug-drug interaction assessment and prediction Risk-based strategies for evaluating biologic drug-drug interactions Strategies to minimize drug-drug interaction risk and mitigate toxic interactions Key regulations governing drug-drug interaction assessments for therapeutic biologics. Drug-Drug Interactions for Therapeutic Biologics is recommended for pharmaceutical and biotechnology scientists, clinical pharmacologists, medicinal chemists, and toxicologists. By enabling these readers to understand how therapeutic biologics may interact with other drugs, the book will help them develop safer, more effective therapeutic biologics.