Dupuytren Disease And Related Diseases The Cutting Edge

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Dupuytren Disease and Related Diseases - The Cutting Edge

Author : Paul M. N. Werker,Joseph Dias,Charles Eaton,Bert Reichert,Wolfgang Wach
Publisher : Springer
Page : 450 pages
File Size : 42,9 Mb
Release : 2016-09-07
Category : Medical
ISBN : 9783319321998

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Dupuytren Disease and Related Diseases - The Cutting Edge by Paul M. N. Werker,Joseph Dias,Charles Eaton,Bert Reichert,Wolfgang Wach Pdf

In this book, leading international experts showcase the latest advances in research into Dupuytren disease and its clinical management. The coverage spans all relevant specialties, including cell biology, biomechanics, genomics, surgery, pharmacotherapy, and radiotherapy. The opening sections address epidemiology, cellular and extracellular events, and genetics. Treatment by means of collagenase injection, percutaneous needle fasciotomy, and other surgical and minimally invasive approaches is then extensively discussed. Comparative studies of different approaches are reviewed, and aspects of patient assessment, examined. The prevention and treatment of disease recurrences are also addressed. Further sections consider related conditions, other treatment options, and future pathways for research. This book should be read by all who treat or conduct research into Dupuytren disease. It is based on presentations delivered at the 2015 International Conference on Dupuytren Disease, held in Groningen, the Netherlands, which was designed to promote a coordinated global response to the disease involving patients, scientists, and clinicians.

Dupuytren’s Disease and Related Hyperproliferative Disorders

Author : Charles Eaton,M. Heinrich Seegenschmiedt,Ardeshir Bayat,Giulio Gabbiani,Paul M. N. Werker,Wolfgang Wach
Publisher : Springer Science & Business Media
Page : 462 pages
File Size : 51,9 Mb
Release : 2012-01-19
Category : Medical
ISBN : 9783642226960

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Dupuytren’s Disease and Related Hyperproliferative Disorders by Charles Eaton,M. Heinrich Seegenschmiedt,Ardeshir Bayat,Giulio Gabbiani,Paul M. N. Werker,Wolfgang Wach Pdf

This book is based on results of the 2010 International Symposium on Dupuytren's disease held in Miami, Florida, but it also includes new data and additional chapters. It is hoped that it will raise awareness of this underestimated condition and promote cooperative efforts to work towards a cure. Up to date information is provided on the epidemiology, biology, and pathology of the disease. The principles and specifics of treatment are explored in detail. The indications for and techniques of radiotherapy, minimally invasive treatments and open surgery are fully explained. The role of physical therapy is considered as well as the care of relapse and complications. The treatment of Ledderhose’s disease and Peyronie’s disease is also discussed. This book provides invaluable information for hand surgeons, podiatrists, orthopedists, radiation therapy specialists and general practitioners. It will help to foster an interdisciplinary approach to the understanding and management of this debilitating disorder.

Dupuytren's Disease

Author : Lawrence C. Hurst,Marie A. Badalamente,David Edward Komatsu
Publisher : Elsevier
Page : 0 pages
File Size : 50,5 Mb
Release : 2023-07
Category : Medical
ISBN : 0443114870

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Dupuytren's Disease by Lawrence C. Hurst,Marie A. Badalamente,David Edward Komatsu Pdf

Dupuytren's Disease: A Scientific Review offers consolidated, up-to-date coverage of both the basic normal (nonpathologic) science and cutting-edge science of this progressive disorder. Drs. Lawrence C. Hurst, Marie A. Badalamente, and David Edward Komatsu break down the complex topic of Dupuytren's contracture into its basic scientific components. Hand surgeons, plastic surgeons, and orthopaedic surgeons will find this unique, concise title to be especially helpful in their practices. Includes chapters on prevalence of Dupuytren's disease, normal genetics and the genetic abnormalities associated with Dupuytren's disease, and collagen and collagen synthesis in healthy fascia and Dupuytren's disease. Provides numerous illustrations throughout. Contains an in-depth bibliography and a useful, complete glossary of related terms. Consolidates today's available information on Dupuytren's science into a single, convenient resource.

Dupuytren's Disease - E-BOOK

Author : Lawrence C. Hurst,Marie A. Badalamente,David Edward Komatsu
Publisher : Elsevier Health Sciences
Page : 144 pages
File Size : 53,7 Mb
Release : 2023-06-02
Category : Medical
ISBN : 9780443114885

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Dupuytren's Disease - E-BOOK by Lawrence C. Hurst,Marie A. Badalamente,David Edward Komatsu Pdf

Dupuytren's Disease: A Scientific Review offers consolidated, up-to-date coverage of both the basic normal (nonpathologic) science and cutting-edge science of this progressive disorder. Drs. Lawrence C. Hurst, Marie A. Badalamente, and David Edward Komatsu break down the complex topic of Dupuytren’s contracture into its basic scientific components. Hand surgeons, plastic surgeons, and orthopaedic surgeons will find this unique, concise title to be especially helpful in their practices. Includes chapters on prevalence of Dupuytren's disease, normal genetics and the genetic abnormalities associated with Dupuytren's disease, and collagen and collagen synthesis in healthy fascia and Dupuytren's disease. Provides numerous illustrations throughout. Contains an in-depth bibliography and a useful, complete glossary of related terms. Consolidates today's available information on Dupuytren’s science into a single, convenient resource.

Collagenase in Dupuytren Disease

Author : Giorgio Pajardi,Marie A. Badalamente,Lawrence C. Hurst
Publisher : Springer
Page : 142 pages
File Size : 48,6 Mb
Release : 2018-07-23
Category : Medical
ISBN : 9783319658223

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Collagenase in Dupuytren Disease by Giorgio Pajardi,Marie A. Badalamente,Lawrence C. Hurst Pdf

This book offers detailed guidance on the use of collagenase, or enzymatic fasciotomy, as a nonsurgical treatment for Dupuytren’s contracture and explains its role in relation to the other forms of treatment, including open fasciectomy, needle aponeurotomy, and lipofilling. Clear guidance is provided on technique, current indications, and off-label usage. With the help of tips and tricks from leading experts, the reader will learn how to personalize the procedure to meet the needs of individual patients. Advice is also provided on all aspects of rehabilitation, which is a key determinant of treatment outcome. Collagenase treatment of Dupuytren’s disease has the benefits of low invasiveness and rapid patient recovery and achieves reasonable recurrence-free periods. It is especially valuable in patients with rapid recurrence following surgery. In documenting and appraising every aspect of its use, this book will be of value for all who treat patients with Dupuytren’s disease, including hand surgeons, orthopedists, plastic surgeons, physiatrists, and physiotherapists.

Dupuytren Disease, An Issue of Hand Clinics E-Book

Author : Steven Haase,Kevin C. Chung
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 45,5 Mb
Release : 2018-07-20
Category : Medical
ISBN : 9780323613897

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Dupuytren Disease, An Issue of Hand Clinics E-Book by Steven Haase,Kevin C. Chung Pdf

This issue of Hand Clinics, guest edited by Dr. Steve Haase, as well as the series’ consulting editor Dr. Kevin Chung, will cover a number of key aspects of Dupuytren Disease. Topics discussed within the issue include, but are not limited to: Risk Factors, Disease Associations, and Dupuytren Diathesis, Pathologic Anatomy in Dupuytren Disease, Needle Aponeurotomy for Dupuytren Disease, Development of Collagenase Treatment for Dupuytren Disease, Collagenase Injection for Dupuytren Disease, Alternative and Adjunctive Treatments for Dupuytren Disease, Comparative Outcomes of Dupuytren Disease Treatment, Complications of Dupuytren Disease Treatment, The Role of Hand Therapy in Dupuytren Disease, Treatment of Recurrent Dupuytren Disease, and Advances in Minimally Invasive Treatment of Dupuytren Disease.

Atlas of Essential Orthopaedic Procedures, Second Edition

Author : Evan Flatow,Alexis C. Colvin
Publisher : Lippincott Williams & Wilkins
Page : 1008 pages
File Size : 52,9 Mb
Release : 2019-07-11
Category : Medical
ISBN : 9781975124878

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Atlas of Essential Orthopaedic Procedures, Second Edition by Evan Flatow,Alexis C. Colvin Pdf

Covering more than 100 fundamental orthopaedic techniques, Atlas of Essential Orthopaedic Procedures, 2nd edition offers a highly illustrated, step-by-step guide to the wide variety of conditions you’re most likely to see in practice. The easy-to-follow format begins with patient selection, walks you through a detailed, step-by-step description of the procedure, and concludes with the author’s surgical pearls—all heavily illustrated with radiographs, intraoperative photographs, and line drawings for optimal visualization of the procedure. This technique-focused reference is an essential resource for busy orthopaedic surgeons and a must-have reference for orthopaedic residency.

Tips and Tricks in Plastic Surgery

Author : Seth R. Thaller,Zubin J. Panthaki
Publisher : Springer Nature
Page : 818 pages
File Size : 40,8 Mb
Release : 2021-12-01
Category : Medical
ISBN : 9783030780289

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Tips and Tricks in Plastic Surgery by Seth R. Thaller,Zubin J. Panthaki Pdf

The book covers the most innovative, contemporary, and common plastic surgery procedures, and aims to improve both reconstructive and aesthetic surgical results while decreasing the incidence of complications. In doing so, patient satisfaction, quality of care, and safety are enhanced. The text provides a wealth of knowledge seeking to enhance results, reduce morbidity, and ensure patient satisfaction. The book consists of five parts, running the gamut of Aesthetic Surgery, Reconstructive Procedures, Pediatric and Craniomaxillofacial Surgery, Adjunctive Procedures, and finally Hand and Upper Extremity. Written by experts in the field, each chapter describes tips and tricks through clear technical details, medical illustrations and, in some chapters, detailed videos. Tips and Tricks in Plastic Surgery serves as a valuable resource for clinicians, professionals and practitioners, as well as medical students on rotation.

Radiation and the Immune System: Current Knowledge and Future Perspectives

Author : Katalin Lumniczky,Serge M. Candéias,Udo S. Gaipl,Benjamin Frey
Publisher : Frontiers Media SA
Page : 283 pages
File Size : 44,5 Mb
Release : 2018-05-03
Category : Electronic
ISBN : 9782889454747

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Radiation and the Immune System: Current Knowledge and Future Perspectives by Katalin Lumniczky,Serge M. Candéias,Udo S. Gaipl,Benjamin Frey Pdf

For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.

Green's Operative Hand Surgery

Author : Scott W. Wolfe,William C. Pederson,Scott H. Kozin,Mark S. Cohen
Publisher : Elsevier Health Sciences
Page : 2617 pages
File Size : 54,8 Mb
Release : 2021-12-03
Category : Medical
ISBN : 9780323697941

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Green's Operative Hand Surgery by Scott W. Wolfe,William C. Pederson,Scott H. Kozin,Mark S. Cohen Pdf

Widely recognized as the gold standard reference in the field, Green's Operative Hand Surgery, 8th Edition, provides complete coverage of the surgical and nonsurgical management of the full range of upper extremity conditions. In a clearly written and well-illustrated format, it contains both foundational content for residents and fellows as well as new approaches, case-based controversies, and outcomes-based solutions for practitioners. Drs. Scott W. Wolfe, William C. Pederson, Scott H. Kozin, and Mark S Cohen, along with new, international contributing authors, provide expert perspectives and preferred methods for all aspects of today’s hand, wrist, and elbow surgery. Contains thoroughly revised and updated indications and techniques to treat the full spectrum of upper extremity disorders. Highlights the latest advances and approaches, such as wide-awake local anesthesia no tourniquet (WALANT) hand surgery, nerve transfer techniques, tendon transfer and tendon avulsion repairs, skin grafting techniques, and more. Offers nearly 140 innovative and high-resolution videos (99 are NEW) that provide real-life, step-by-step guidance on key procedures. Provides state-of-the-art information on wrist arthritis, hand trauma, new arthroplasties, targeted muscle reinnervation, wrist instability surgeries, fracture management, rehabilitation, congenital disorders, orthotic interventions, and more. Includes newly updated, high-resolution illustrations, images, and photos throughout. Presents case-based controversies and unique solutions, plus current views on what works and what does not, based on recent science and outcome measures.

Medical Misadventures

Author : Alistair Fraser-Moodie
Publisher : Troubador Publishing Ltd
Page : 616 pages
File Size : 43,7 Mb
Release : 2018-03-28
Category : Medical
ISBN : 9781789010954

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Medical Misadventures by Alistair Fraser-Moodie Pdf

A memoir looking at the ups and downs of a doctor’s life. A ‘warts and all’ examination of the NHS through the last 50 years. The book also looks at the looming crisis in the NHS when the number of doctors will dramatically fall.

Essential Surgery E-Book

Author : Simon J.F. Harper,Kourosh Saeb-Parsy
Publisher : Elsevier Health Sciences
Page : 687 pages
File Size : 49,8 Mb
Release : 2013-08-06
Category : Medical
ISBN : 9780702054839

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Essential Surgery E-Book by Simon J.F. Harper,Kourosh Saeb-Parsy Pdf

Essential Surgery is a comprehensive and highly illustrated textbook suitable for both clinical medical students as well junior surgical trainees, preparing for postgraduate qualifications in surgery such as the MRCS. Covering general surgery, trauma, orthopaedics, vascular surgery, paediatric surgery, cardiothoracic surgery and urology, it incorporates appropriate levels of basic science throughout. The book is ideal for modern clinical courses as well as being a practical manual for readers at more advanced levels. Its main aim is to stimulate the reader to a greater enjoyment and understanding of the practice of surgery. Essential Surgery incorporates a problem-solving approach wherever possible, emphasising how diagnoses are made and why particular treatments are used. The pathophysiological basis of surgical diseases is discussed in relation to their management, acting as a bridge between basic medical sciences and clinical problems. The uniformity of the writing style and the clarity of elucidation will encourage continued reading, while the emphasis on the principles of surgery will enable a real understanding of the subject matter. The book’s extensive use of original illustrations, boxes and tables emphasises important concepts and will aid revision. The principles of operative surgery and perioperative care are explained together with outlines of common operations, enabling students and trainee surgeons to properly understand procedures and to participate intelligently in the operating department. A major revision of the text has taken full account of the progressive evolution of surgery and includes new concepts that have advanced medical understanding. New topics have been added to ensure the book’s contents match the curriculum of the UK Intercollegiate MRCS examination, including patient safety, surgical ethics, communication, consent, clinical audit and principles of research. The broad experience of surgical teaching and training of two new authors has brought a fresh perspective on the book’s contents and its presentation. New consensus guidelines for managing common disorders have been incorporated where appropriate.

Dupuytren’s Disease

Author : Peter Brenner,Ghazi M. Rayan
Publisher : Springer Science & Business Media
Page : 264 pages
File Size : 53,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709160619

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Dupuytren’s Disease by Peter Brenner,Ghazi M. Rayan Pdf

Morbus Dupuytren is particularly widespread among northern Europeans. However, the therapeutic success-rate often leaves much to be desired. A 50% recurrence-rate after surgery indicates that the disease cannot be treated by surgery alone. This book therefore adopts two parallel approaches: emphasis is firstly placed on the systemic character of morbus Dupuytren in context with other connective tissue diseases by a description of the biochemical and molecular-biological changes in the diseased connective tissues; secondly, a diversified picture of the given anatomical facts serves to explain the employment of the various therapeutic approaches. Further, a description is given of the current surgical procedures.