Eicosanoids And Other Bioactive Lipids In Cancer Inflammation And Radiation Injury 3
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Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Robert L. Jones,Patrick Y-K Wong
Author : Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Robert L. Jones,Patrick Y-K Wong Publisher : Springer Science & Business Media Page : 578 pages File Size : 54,9 Mb Release : 2013-11-21 Category : Medical ISBN : 9781489918130
Eicosanoids and other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 3 by Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Robert L. Jones,Patrick Y-K Wong Pdf
Proceedings of the Fourth International Conference held in Hong Kong, October 4-7, 1995
Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Charles N. Serhan,Edward A. Dennis
Author : Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Charles N. Serhan,Edward A. Dennis Publisher : Springer Science & Business Media Page : 592 pages File Size : 40,9 Mb Release : 2012-12-06 Category : Science ISBN : 9781461501930
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5 by Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Charles N. Serhan,Edward A. Dennis Pdf
This volume represents a collection of contributions from the 6th International Conference on Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Related Diseases held in Boston from September 12-15, 1999. The mission of this meeting was to bring together senior and junior investigators to both announce and examine their recent advancements in cutting-edge research on the roles and actions of lipid mediators and their impact in human physiology and disease pathogenesis. The meeting focused on new concepts in these areas of interest to both clinicians and researchers. The program included several outstanding plenary lectures and presentations by leading experts in the fields of cancer and inflammation. In addition, the Boston meeting presented three Young Investigator awards, one in each of the major focus areas. The meeting was exciting and proved to be very memorable. The program was developed with an emphasis on recent advances in molecular and of lipid mediators relevant in cellular mechanisims involved in the formation and actions inflammation and cancer. Plenary lectures were presented by Prof. Bengt Sammuelsson (Karolinska Institute, Stockholm; 1982 Nobel Laureate in Physiology or Medicine) and Prof. E. 1. Corey (Harvard University; 1990 Nobel Laureate in Chemistry). Both of these plenary lectures were held on Day 1, which set an exciting tone for this meeting. Immediately following these plenary lectures, three simultaneous breakout sessions were held, one of inflammation, a second on cancer and synthesis of novel inhibitors, and a third on enzymes-lipoxygenases/cyclooxygenases and inhibitors.
Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Edward A. Dennis
Author : Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Edward A. Dennis Publisher : Springer Science & Business Media Page : 660 pages File Size : 44,8 Mb Release : 2013-12-01 Category : Science ISBN : 9781461547938
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 4 by Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Edward A. Dennis Pdf
This book contains conference presentations regarding the regulation of eicosanoid enzymes and, in particular, cyclooxygenases, lipoxygenases, and phospholipases. The new field of isoprostanes is also represented.
Santosh Nigam,Kenneth V. Honn,Lawrence J. Marnett,Thomas Walden Jr.
Author : Santosh Nigam,Kenneth V. Honn,Lawrence J. Marnett,Thomas Walden Jr. Publisher : Springer Science & Business Media Page : 765 pages File Size : 53,6 Mb Release : 2012-12-06 Category : Medical ISBN : 9781461535201
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury by Santosh Nigam,Kenneth V. Honn,Lawrence J. Marnett,Thomas Walden Jr. Pdf
In recent decades eicosanoids have been attracting an increasing amount of attention as a result of their important physiological roles in many areas of biology and medicine. The eicosanoids comprise the prostaglandins, thromboxanes and leukotrienes and are products of arachidonic acid, an essential polyunsaturated fatty acid stored in tissue phospholipids. Disturbances of eicosanoids and their metabolic products play a regulatory role in many types of cell injuries and diseases. One of the most exciting areas of eicosanoid research pinpoints their participation in the control of cell proliferation and differentiation. Eicosanoids form a link between different fields of research into such areas as cancer, inflammation and radiation-induced injury. This link provided the impetus for the development of the conference series of which the present volume represents the proceedings of the Second International Conference, held in Berlin in October 1991.
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2 by Kenneth V. Honn,Santosh Nigam,Lawrence J. Marnett Pdf
Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction. One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2 by Kenneth V. Honn,Santosh Nigam,Lawrence J. Marnett Pdf
Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction. One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.
Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Thomas Walden Jr.
Author : Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Thomas Walden Jr. Publisher : Springer Science & Business Media Page : 493 pages File Size : 42,6 Mb Release : 2012-12-06 Category : Medical ISBN : 9781461538745
Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury by Kenneth V. Honn,Lawrence J. Marnett,Santosh Nigam,Thomas Walden Jr. Pdf
This volume contains the proceedings of the First International Conference on Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury held in Detroit, Michigan on October 11-14, 1989. The program consisted of 83 oral and 29 poster presentations, 74 of which are included in these proceedings. The major sponsors of the conference were the Armed Forces Radiobiology Research Institute, located in Bethesda, Maryland, the Radiation Oncology Research and Development Center of the Gershenson Radiation Oncology Center, Harper Hospital in Detroit, Michigan, and Schering AG of West Germany. Eighteen other organizations provided additional support. The conference was unique in its attempt to link the eicosanoid and lipid researchers in the radiobiology and cancer disciplines. The diverse roles that eicosanoids and other bioactive lipids play in these biological phenomena including the participation of lipid oxidation in conversion of procarcinogens, positive and negative modulation of tumor growth, immunomodulation, tissue injury, and yet protection and enhancement of cancer therapy, necessitated scientific interaction to sort out and understand these complex and sometimes contradictory observations. The success of this effort is reflected not only through these proceedings, but also through the decision to continue the conference series with a second meeting to be held in Berlin between September 17-21, 1991.
Dietary Omega-3 Polyunsaturated Fatty Acids and Cancer by Gabriella Calviello,Simona Serini Pdf
Dietary Omega-3 Polyunsaturated Fatty Acids and Cancer provides all the latest information on the possible benefits of omega-3 polyunsaturated fatty acids (PUFAs) against a wide series of cancers. Several influential scientists in this field have contributed to make this book unique amongst the others published so far in this field. The chapters give detailed information about the results obtained in this field through experimental studies conducted on both animals and cultured cells, as well as through human intervention trials and epidemiological observational studies. This book represents an important tool for researchers working in nutrition and oncology, since it collects all the knowledge about omega-3 PUFAs and cancer, even the most recent, in a single publication. For the first time controversies among the different studies are also covered with great detail in this book. The book enables physicians to clearly understand on a scientific basis if their oncologic patients or patients at risk of cancer could actually benefit from a diet enriched in omega-3 PUFAs or from a dietary supplementation with these fatty acids. The book represents also a good resource for ordinary individuals as well as cancer patients to learn more about omega-3 PUFAs and understand how these dietary components may affect cancer growth.
Paula B. Andrade,Patrícia Valentão,David M. Pereira
Author : Paula B. Andrade,Patrícia Valentão,David M. Pereira Publisher : John Wiley & Sons Page : 348 pages File Size : 40,5 Mb Release : 2017-12-04 Category : Medical ISBN : 9783527342051
Natural Products Targeting Clinically Relevant Enzymes by Paula B. Andrade,Patrícia Valentão,David M. Pereira Pdf
The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products cover the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.
Lipid Second Messengers by Ronald P. Rubin,Suzanne Laychock Pdf
Lipid Second Messengers provides detailed methodology for analysis of various lipid signaling pathways. Authoritative contributors explain the factors that regulate lipid second messenger production by agonist-activated enzymes and examine their products. Topics discussed include procedures used to measure lipid-derived mediators such as lysophospholipids, arachidonic acid, eicosanoids, anandamide, and ceramides, and the enzymes responsible for generating these messengers, such as phospholipases, prostaglandin endoperoxide synthases, and sphingomyelinase.
Therapeutic Platform of Bioactive Lipids by Manjari Singh Pdf
Bioactive lipid metabolism and signaling are now widely accepted as major players in cancer biology. This volume helps to fill the urgent need to explore and investigate the innovations, current shortcomings, and future challenges of cancer therapy through the bioactive lipids by presenting new research on the use of bioactive lipids as effective weapons against cancer. The volume introduces the subject and then goes on to cover the chemistry, formulation, and mechanism of bioactive lipids in cancer. The volume takes a close look at lipoxins, ceramides, resolvins, and sphingosine-1-phosphate and their roles in cancer treatment. It also addresses the formulations based on bioactive lipids for the treatment of cancer. A variety of mechanisms of bioactive lipids as novel therapies are also covered, including using computational techniques to identify bioactive lipid drug targets, targeting therapy via KRAS and PI3K signals, and others. The authors also discuss the role and effects of various substances and their effect on various cancers, including colorectal cancer, prostate cancer, breast cancer, and others. The application of lysophosphatidic acid, lipopolysaccharide, lipid-soluble bioactive substance from avocado, omega-3 polyunsaturated fatty acids-derived lipid metabolites, and more are covered as well. The volume offers academia, technologists, and scientists from different disciplines valuable information to gain knowledge of bioactive lipid metabolism and signaling as an anti-cancer weapon in their fight against cancer.
