Embryonic Stem Cells

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Stem Cells and the Future of Regenerative Medicine

Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Stem Cells and the Future of Regenerative Medicine Book PDF

Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Publisher : National Academies Press
Page : 112 pages
File Size : 52,5 Mb
Release : 2002-01-25
Category : Science
ISBN : 9780309170420

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Stem Cells and the Future of Regenerative Medicine by Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research Pdf

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Guidelines for Human Embryonic Stem Cell Research

National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on Guidelines for Human Embryonic Stem Cell Research
Guidelines for Human Embryonic Stem Cell Research Book PDF

Author : National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on Guidelines for Human Embryonic Stem Cell Research
Publisher : National Academies Press
Page : 224 pages
File Size : 51,9 Mb
Release : 2005-09-15
Category : Medical
ISBN : 9780309096539

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Guidelines for Human Embryonic Stem Cell Research by National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on Guidelines for Human Embryonic Stem Cell Research Pdf

Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.

Human Embryonic Stem Cells

Arlene Chiu,Mahendra S. Rao
Human Embryonic Stem Cells Book PDF

Author : Arlene Chiu,Mahendra S. Rao
Publisher : Springer Science & Business Media
Page : 455 pages
File Size : 48,8 Mb
Release : 2003-08-01
Category : Science
ISBN : 9781592594238

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Human Embryonic Stem Cells by Arlene Chiu,Mahendra S. Rao Pdf

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Human Embryonic Stem Cells

Ann A. Kiessling,Scott Anderson
Human Embryonic Stem Cells Book PDF

Author : Ann A. Kiessling,Scott Anderson
Publisher : Jones & Bartlett Learning
Page : 240 pages
File Size : 41,6 Mb
Release : 2003
Category : Medical
ISBN : 076372341X

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Human Embryonic Stem Cells by Ann A. Kiessling,Scott Anderson Pdf

The emerging field of human embryonic stem cell biomedicine crosses many disciplinary boundaries-cell biology, reproductive biology, embryology, molecular biology, endocrinology, immunology, fetal med

Stem Cells

Christine Mummery,Anja van de Stolpe,Bernard Roelen,Hans Clevers
Stem Cells Book PDF

Author : Christine Mummery,Anja van de Stolpe,Bernard Roelen,Hans Clevers
Publisher : Academic Press
Page : 448 pages
File Size : 54,9 Mb
Release : 2014-05-23
Category : Science
ISBN : 9780124115675

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Stem Cells by Christine Mummery,Anja van de Stolpe,Bernard Roelen,Hans Clevers Pdf

The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice

The Human Embryonic Stem Cell Debate

Suzanne Holland,Karen Lebacqz,Laurie Zoloth
The Human Embryonic Stem Cell Debate Book PDF

Author : Suzanne Holland,Karen Lebacqz,Laurie Zoloth
Publisher : MIT Press
Page : 294 pages
File Size : 41,9 Mb
Release : 2001
Category : Bioethics
ISBN : 0262582082

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The Human Embryonic Stem Cell Debate by Suzanne Holland,Karen Lebacqz,Laurie Zoloth Pdf

Discusses the ethical issues involved in the use of human embryonic stem cells in regenerative medicine.

Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research
Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research
Publisher : National Academies Press
Page : 112 pages
File Size : 49,7 Mb
Release : 2007-03-22
Category : Medical
ISBN : 9780309179607

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Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research Pdf

It is widely understood that stem cell treatments have the potential to revolutionize medicine. Because of this potential, in 2004 California voters approved Proposition 71 to set up a 10-year, $3 billion program to fund research on stem cells. Under the direction of the California Institute for Regenerative Medicine, this program will pay to build facilities for stem cell research and will fund doctors and scientists to carry out research with the ultimate goal of helping to develop therapies based on stem cells. For this research to move forward, however, will require a steady supply of stem cells, particularly human embryonic stem cells. Those stem cells are collected from developing human embryos created from eggs-or oocytes-harvested from the ovaries of female donors. Thus much of the promise of stem cells depends on women choosing to donate oocytes to the research effort. The oocyte donation process is not without risk, however. Donors are given doses of hormones to trigger the production of more eggs than would normally be produced, and this hormone treatment can have various side effects. Once the eggs have matured in the ovary, they must be retrieved via a surgical procedure that is typically performed under anesthesia, and both the surgery and the anesthesia carry their own risks. Furthermore, given the very personal nature of egg donation, the experience may carry psychological risks for some women as well. With this in mind, in 2006 the California Institute for Regenerative Medicine contracted with the National Academies to organize a workshop that would bring together experts from various areas to speak about the potential risks of oocyte donation and to summarize what is known and what needs to be known about this topic. The Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research was formed to plan the workshop, which was held in San Francisco on September 28, 2006. This report is a summary and synthesis of that workshop.

The Ethics of Embryonic Stem Cell Research

Katrien Devolder
The Ethics of Embryonic Stem Cell Research Book PDF

Author : Katrien Devolder
Publisher : OUP Oxford
Page : 176 pages
File Size : 52,9 Mb
Release : 2015-01-22
Category : Philosophy
ISBN : 9780191036224

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The Ethics of Embryonic Stem Cell Research by Katrien Devolder Pdf

Embryonic stem cell research holds unique promise for developing therapies for currently incurable diseases and conditions, and for important biomedical research. However, the process through which embryonic stem cells are obtained involves the destruction of early human embryos. Katrien Devolder focuses on the tension between the popular view that an embryo should never be deliberately harmed or destroyed, and the view that embryonic stem cell research, because of its enormous promise, must go forward. She provides an in-depth ethical analysis of the major philosophical and political attempts to resolve this tension. One such attempt involves the development of a middle ground position, which accepts only types or aspects of embryonic stem cell research deemed compatible with the view that the embryo has a significant moral status. An example is the position that it can be permissible to derive stem cells from embryos left over from in vitro fertilisation but not from embryos created for research. Others have advocated a technical solution. Several techniques have been proposed for deriving embryonic stem cells, or their functional equivalents, without harming embryos. An example is the induced pluripotent stem cell technique. Through highlighting inconsistencies in the arguments for these positions, Devolder argues that the central tension in the embryonic stem cell debate remains unresolved. This conclusion has important implications for the stem cell debate, as well as for policies inspired by this debate.

Stem Cells

Muireann Quigley,Sarah Chan,John Harris
Stem Cells Book PDF

Author : Muireann Quigley,Sarah Chan,John Harris
Publisher : World Scientific
Page : 297 pages
File Size : 52,7 Mb
Release : 2012
Category : Medical
ISBN : 9789814374248

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Stem Cells by Muireann Quigley,Sarah Chan,John Harris Pdf

Fiction. LGBT Studies. Finalist for the American Library Association GLBT Fiction Award. "Guess deftly performs the parlor trick of handling several different voices, switching fluidly from perceptive Caddie to the clipped cadence of masculine Jo to jaded Selena. This Alice Doesn't Live Here Anymore for the 1990s celebrates the differences between people without fudging the loneliness that these entail. Guess's attempts to put a Midwestern spin on magical realism are blessedly rare: in a book loaded with so many natural surprises, any supernatural extras would be gilt on the lily"—Publishers Weekly.

The Cell Biology of Stem Cells

Eran Meshorer,Kathrin Plath
The Cell Biology of Stem Cells Book PDF

Author : Eran Meshorer,Kathrin Plath
Publisher : Springer Science & Business Media
Page : 246 pages
File Size : 40,5 Mb
Release : 2011-01-11
Category : Science
ISBN : 9781441970374

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The Cell Biology of Stem Cells by Eran Meshorer,Kathrin Plath Pdf

Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attractive model for the study of basic biological questions such as cell division, replication, transcription, cell fate decisions, and more. With embryonic stem (ES) cells that can generate each cell type in the mammalian body and adult stem cells that are able to give rise to the cells within a given lineage, basic questions at different developmental stages can be addressed. Importantly, both adult and embryonic stem cells provide an excellent tool for cell therapy, making stem cell research ever more pertinent to regenerative medicine. As the title The Cell Biology of Stem Cells suggests, our book deals with multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming. In the first chapter, “Early embryonic cell fate decisions in the mouse”, Amy Ralson and Yojiro Yamanaka describe the mechanisms that support early developmental decisions in the mouse pre-implantation embryo and the current understanding of the source of the most immature stem cell types, which includes ES cells, trophoblast stem (TS) cells and extraembryonic endoderm stem (XEN) cells.

Differentiation of Embryonic Stem Cells

Anonim
Differentiation of Embryonic Stem Cells Book PDF

Author : Anonim
Publisher : Elsevier
Page : 509 pages
File Size : 52,5 Mb
Release : 2003-12-18
Category : Science
ISBN : 0080546161

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Differentiation of Embryonic Stem Cells by Anonim Pdf

This volume covers all aspects of embryonic stem cell differentiation, including mouse embryonic stem cells, mouse embryonic germ cells, monkey and human embryonic stem cells, and gene discovery. * Early commitment steps and generation of chimeric mice * Differentiation to mesoderm derivatives * Gene discovery by manipulation of mouse embryonic stem cells

Essentials of Stem Cell Biology

Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Wilmut
Essentials of Stem Cell Biology Book PDF

Author : Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Wilmut
Publisher : Academic Press
Page : 681 pages
File Size : 43,9 Mb
Release : 2009-06-05
Category : Science
ISBN : 9780080884974

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Essentials of Stem Cell Biology by Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Wilmut Pdf

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries Contributions by Nobel Laureates and leading international investigators Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references

Stem Cells, Human Embryos and Ethics

Lars Østnor
Stem Cells Human Embryos and Ethics Book PDF

Author : Lars Østnor
Publisher : Springer Science & Business Media
Page : 258 pages
File Size : 52,6 Mb
Release : 2008-04-03
Category : Science
ISBN : 9781402069895

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Stem Cells, Human Embryos and Ethics by Lars Østnor Pdf

Is it acceptable from an ethical point of view to use stem cells from human embryos for scientific research and clinical therapy? And what are the weaknesses and strengths of various opinions and positions when they are critically evaluated? These are the main problems dealt with in this book. The various chapters as a whole give a comprehensive, many-sided and balanced discussion of the subject. The book contains contributions from biological, medical, social, political, philosophical and theological perspectives. The authors have been chosen because of their professional competence, many of them being respected scholars on a top international level. They give an updated contribution from their own discipline in order to enlighten the different aspects of the common theme. The authors cover various positions and evaluations with regard to the question of the use of embryonic stem cells for research and therapy. The book is written for several audiences: a) scholars and professionals working with stem cell research or with the ethical questions arising from this field (people from biology, medicine, law, philosophy, theology etc.), b) advanced and graduate students within the same professional disciplines and c) politicians and the general public interested in the burning ethical problems which are intensively debated in many countries.

Stem Cell Now

Christopher Thomas Scott
Stem Cell Now Book PDF

Author : Christopher Thomas Scott
Publisher : Penguin
Page : 273 pages
File Size : 51,9 Mb
Release : 2006-08-29
Category : Science
ISBN : 9781101213346

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Stem Cell Now by Christopher Thomas Scott Pdf

THE STEM CELL IS SET TO DOMINATE POPULAR AWARENESS OF SCIENCE LIKE THE ATOM BOMB DID A GENERATION AGO. No area of science holds such immediate promise for treating disease and improving human lives as stem cell research. But no area of science also causes such fundamental ethical concern and such ferocious political conflict.

Embryonic Stem Cell Protocols

Kursad Turksen
Embryonic Stem Cell Protocols Book PDF

Author : Kursad Turksen
Publisher : Springer Science & Business Media
Page : 504 pages
File Size : 46,5 Mb
Release : 2008-02-04
Category : Science
ISBN : 9781597450379

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Embryonic Stem Cell Protocols by Kursad Turksen Pdf

Now in two volumes, this completely updated and expanded edition of Embryonic Stem Cells: Methods and Protocols provides a diverse collection of readily reproducible cellular and molecular protocols for the manipulation of nonhuman embryonic stem cells. Volume one, Embryonic Stem Cell Protocols: Isolation and Characterization, Second Edition, provides a diverse collection of readily reproducible cellular and molecular protocols for the isolation, maintenance, and characterization of embryonic stem cells. The second volume, Embryonic Stem Cell Protocols: Differentiation Models, Second Edition, covers state-of-the-art methods for deriving many types of differentiating cells from ES cells. Together, the two volumes illuminate for both novices and experts our current understanding of the biology of embryonic stem cells and their utility in normal tissue homeostasis and regenerative medicine applications.