Emerging Biomarkers In Personalized Therapy Of Urologic Tumors
Emerging Biomarkers In Personalized Therapy Of Urologic Tumors Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Emerging Biomarkers In Personalized Therapy Of Urologic Tumors book. This book definitely worth reading, it is an incredibly well-written.
Emerging Biomarkers in Personalized Therapy of Urologic Tumors by Rodolfo Montironi,Matteo Santoni,Alessia Cimadamore,Antonio Lopez-Beltran,Liang Cheng Pdf
The identification of effective biomarkers has becoming a major focus in cancer research, mainly due to the necessity of selecting potentially responsive patients in order to improve their outcomes, as well as to reduce the toxicity and costs related to ineffective treatments. In genitourinary tumors, the lack of biomarkers does not allow for the development of personalized strategies for a single patient, thus representing a major goal in this field. This eBook includes the description of these emerging techniques and identify the most promising biomarkers in genitourinary tumors.
Biomarkers in Urology, An Issue of Urologic Clinics, E-Book by Adam Feldman Pdf
In this issue of Urologic Clinics of North America, guest editor Dr. Adam Feldman brings his considerable expertise to the topic of Biomarkers in Urology. The use of biomarkers in clinical practice can range from screening, to refined detection in an at-risk population, to risk stratification following diagnosis, to prognostication following therapy. A better understanding of tumor biology and genetic heterogeneity will lead clinicians to adopt clinical paradigms that utilize sequences of biomarker assessments. In this issue, key experts help you remain at the forefront of the care of urologic malignancies by providing a timely update on emerging biomarkers in urology. Contains 15 practice-oriented topics including biomarkers in pediatric urology; unleashing the urinary microbiome in benign urologic disease; biomarkers for detection and assessment of clinically significant prostate cancer; biomarkers in testicular cancer: classic tumor markers and beyond; and more. Provides in-depth clinical reviews on biomarkers in urology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Role of Biomarkers in Medicine by Mu Wang,Frank Witzmann Pdf
The use of biomarkers in basic and clinical research has become routine in many areas of medicine. They are accepted as molecular signatures that have been well characterized and repeatedly shown to be capable of predicting relevant disease states or clinical outcomes. In Role of Biomarkers in Medicine, expert researchers in their individual field have reviewed many biomarkers or potential biomarkers in various types of diseases. The topics address numerous aspects of medicine, demonstrating the current conceptual status of biomarkers as clinical tools and as surrogate endpoints in clinical research. This book highlights the current state of biomarkers and will aid scientists and clinicians to develop better and more specific biomarkers for disease management.
Biomarkers in Urologic Cancer, An Issue of Urologic Clinics of North America, E-Book by Kevin R. Loughlin Pdf
The past decade has been marked by the acceleration of our understanding of the molecular biology of cancer. Simultaneously, there have been increasing exigencies to diagnose, treat and follow cancer patients more economically. Biomarkers represent the marriage of science and economics. Biomarkers offer the potential to increase the precision of diagnosis, prognosis, and surveillance of urological malignancies. This issue presents the cutting-edge advances of biomarker technology to urologic oncology.
Liquid Biopsy in Urogenital Cancers and its Clinical Utility by Seyed Mohammad Kazem Aghamir Pdf
Liquid Biopsy in Urogenital Cancers and Their Clinical Utility presents updated information on liquid biopsy techniques and their utility for diagnosing urological cancers. As a promising and recent diagnostic method, these techniques can be used for identifying tumors at initial stage, thus greatly improving treatment outcomes and survivorship. Chapters provide an overview of liquid biopsy as a new tool for diagnosis, monitoring and personalized medicine in urogenital cancers and explain its applicability in different cancer types, including bladder, prostate, kidney and testis tumors, female genital tract and pediatric urogenital tumors. This is a valuable resource for cancer researchers, oncologists, graduate students, urologists and biomedical researchers who need to understand more about liquid biopsy and its use for urogenital cancers. Presents an overview on liquid biopsy techniques and their applications in cancer diagnosis Explains how to extract circulating tumor DNA, RNA and circulating tumor cells and extracellular vehicles from blood samples to identify the urology cancers, including testis, prostate, bladder and kidney Includes several images and schematic diagrams that illustrate content and facilitate its comprehension
Cancer Biomarkers in Body Fluids by Gabriel D. Dakubo Pdf
The ability to measure and monitor cancer biomarkers in “body fluid biopsy” should greatly impact oncologic practice. “Biomarkers in Proximal Fluids”, the third of the “Cancer Biomarkers in Body Fluids” series details cancer signatures in none or minimally circulating body fluids including saliva, sputum, bronchoalveolar lavage fluid, exhaled breath condensate, nipple aspirate fluid, gastric and pancreatic juice, stool, urine, and prostatic, peritoneal and cerebrospinal fluid. These fluids are enriched with biomarkers, especially those emanating from cells of the proximal tissue. Chapter 1 examines the global burden of cancer and the need for regional efforts at primary prevention, early detection and patient care. Chapters 2-12 address tissue-specific biomarkers in associated body fluids. The tumor interstitial fluid as a microenvironment rich in cancer biomarkers is detailed in chapter 13, while chapter 14 looks at the human body fluid microbiome and its evolving role in cancer. Commercially available assays using proximal fluids are examined at the end of the respective chapters. This book complements its predecessors and is equally useful to oncologists, cancer researchers, clinicians, medical students, nurses, diagnostic laboratory and pharmaceutical industry personnel.
Author : Michael L. Blute,Steven L. Chang Publisher : Elsevier Health Sciences Page : 209 pages File Size : 49,6 Mb Release : 2023-03-24 Category : Medical ISBN : 9780443182877
Renal Cancer: Old and New Paradigms , An Issue of Urologic Clinics, E-Book by Michael L. Blute,Steven L. Chang Pdf
In this issue of Urologic Clinics of North America, guest editors Drs. Michael L. Blute and Steven L. Chang bring their considerable expertise to the topic of Renal Cancer: Old and New Paradigms. Recent significant advances in the management of renal cancer have expanded beyond simply eliminating disease to preserving and optimizing quality of life. In this issue, top experts highlight historical perspectives as well as current status and future treatments of renal cancer. Contains 13 practice-oriented topics on biomarkers for the detection and surveillance of renal cancer; the changing role of renal mass biopsy; renal cysts: an oncological conundrum; the surgical management of renal cancer with inferior vena caval thrombus; integrating surgery in the multidisciplinary care of advanced renal cancer; and more. Provides in-depth clinical reviews on renal cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
The Elusive Road Towards Effective Cancer Prevention and Treatment by Franklyn De Silva,Jane Alcorn Pdf
Cancer will remain a global major health problem unless new diagnostic, prognostic, and management approaches are discovered to address both loss of life and quality of life. Here we summarize the general physiology, pathology, heterogeneity, and evolution of cancer, current status, limitations and challenges associated with prevention, incidence, treatment, survival, and mortality, as well as future directions with regards to solid tumors. Perspectives are provided on how to improve pre-clinical understandings, outcomes, and patient care. Further, this comprehensive, timely overview of the literature has educational value as part of an academic course, seminar, or as a supplementary text.
P5 eHealth: An Agenda for the Health Technologies of the Future by Gabriella Pravettoni,Stefano Triberti Pdf
This open access volume focuses on the development of a P5 eHealth, or better, a methodological resource for developing the health technologies of the future, based on patients’ personal characteristics and needs as the fundamental guidelines for design. It provides practical guidelines and evidence based examples on how to design, implement, use and elevate new technologies for healthcare to support the management of incurable, chronic conditions. The volume further discusses the criticalities of eHealth, why it is difficult to employ eHealth from an organizational point of view or why patients do not always accept the technology, and how eHealth interventions can be improved in the future. By dealing with the state-of-the-art in eHealth technologies, this volume is of great interest to researchers in the field of physical and mental healthcare, psychologists, stakeholders and policymakers as well as technology developers working in the healthcare sector.
Advances in Molecular Nanotechnology Research and Application: 2011 Edition by Anonim Pdf
Advances in Molecular Nanotechnology Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Molecular Nanotechnology. The editors have built Advances in Molecular Nanotechnology Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Molecular Nanotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Molecular Nanotechnology Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Cancer Biomarkers by Debmalya Barh,Angelo Carpi,Mukesh Verma,Mehmet Gunduz Pdf
Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer markers that are under development or currently in use. It deals with a majority of commonly prevalent cancers and can help anyone working in the health-care industry to recommend or develop early diagnostics, at-risk tests, and prognostic biomarkers for various cancers. It explores the practice of determining biomarkers by their characteristics and relative methodologies, and presents the most recent data as well as a number of current and upcoming early diagnostic noninvasive molecular markers for many common cancers. It also considers the sensitivity and specificity of markers, biomarker market, test providers, and patent information. Approximately 30-35 Cancer Specific Noninvasive Molecular Diagnostic Markers in a Single Volume The book details the general and technical aspects of noninvasive cancer markers. It covers imaging, cutting-edge molecular technologies for biomarker development, and noninvasive or minimally invasive sources of molecular markers, as well as quality control and ethical issues in cancer biomarker discovery. It also provides a detailed account of brain, head and neck, and oral cancer markers, and provides information on a number of gastrointestinal cancers, lung cancer, and mesothelioma markers. Emphasizes the Importance of Volatile Markers in Early Cancer Diagnosis Presents noninvasive early molecular markers in urological cancers Describes gynecological and endocrine cancer markers Details noninvasive markers of breast, ovarian, cervical, and thyroid cancers Addresses hematological malignancies Contains information on noninvasive molecular markers in myelodysplastic syndromes, acute myeloid leukemia, Hodgkin’s lymphoma, and multiple myeloma Provides comprehensive information on diagnostic and prognostic biomarkers in cutaneous melanoma This text considers molecular technologies for biomarker development, noninvasive or minimally invasive sources of molecular markers, and quality control and ethical issues in cancer biomarker discovery.
Author : William C. Huang,Samir S. Taneja Publisher : Elsevier Health Sciences Page : 153 pages File Size : 54,9 Mb Release : 2012-05-08 Category : Medical ISBN : 9781455744442
Evolving Treatment Paradigms in Renal Cancer, An Issue of Urologic Clinics - E-Book by William C. Huang,Samir S. Taneja Pdf
This issue of the Urologic Clinics provides a timely update on Renal Cancer and the evolving treatment standards in urology. Articles include Contemporary Imaging of the Renal Mass, Surgical Approach to Multifocal Renal Cancers, and Systemic Therapy Prior to Surgery. Effects of the various existing surgical approaches on long-term renal function is also discussed, along with a review of the current trends in surgical management of renal cancers with specific attention to utilization of laparoscopic approach, partial nephrectomy, ablative technologies and observation.
Cross-Talk and Interaction between Endocrinology and Urology: Challenges and Opportunities by Xiao-qiang Liu,Yuxuan Song,Caigan Du Pdf
The genitourinary system is closely related to the endocrine system. Some genitourinary organs are endocrine organs themselves. Over the past decades, the diagnosis and treatment on both endocrine and urological diseases have developed rapidly. Concerns regarding the normal growth, development, and physiological functions of the genitourinary system, as well as the pathogenesis and treatment of urinary diseases have been raised. The diseases from these two different systems belong to the specialties of internal medicine and surgery respectively. For example, prostate is regulated by androgen originates from testis, adrenal and even malignancies. Androgen deprivation therapy has definite effect on prostatic adenocarcinoma but may also develop castration resistance. The disorders of gonad and reproductive health are also implicated in hormone regulation, such as delayed hypogonadism. Many diseases such as Cushing's syndrome and aldosteronism are transdisciplinary. However, the research on the normal physiological function, and the comprehensive diagnosis and treatment of both systems are short of cross-integration, resulting in a lack of close cooperation between physicians and surgeons. We are calling for more attention on the joint participation in multidisciplinary diagnosis and treatment, as well as collaboration on basic research in the field of genitourinary and endocrine diseases.
Bladder cancer is one of the most exciting urological cancers. It exists in two forms - non-muscle-invasive (NMI) and muscle-invasive (MI) disease. The difference in the clinical picture has been the focus of significant research in defining the molecular characteristics of urothelial cancer (UC) of the bladder. This book provides an overview of the most hotly debated areas in bladder cancer. Authors have focused on the emerging role of markers for NMI UC and various ways of improving the efficacy of current chemotherapy in the first section. The second section has focused on the surgical aspects of MI UC. Two major areas of debate - the role of pelvic lymph node dissection and genital sparing surgery - are discussed in this section.
Cancer cell reprogramming: Impact on carcinogenesis and cancer progression by Ira Ida Skvortsova,Elvira V. Grigorieva,Simona Kranjc Brezar,Yue Zhao Pdf