Eosinophil Ultrastructure

Author : Rossana C.N. Melo,Ann M. Dvorak,Peter F. Weller
Publisher : Academic Press
Page : 520 pages
File Size : 54,6 Mb
Release : 2023-01-05
Category : Medical
ISBN : 9780128137567

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Eosinophil Ultrastructure by Rossana C.N. Melo,Ann M. Dvorak,Peter F. Weller Pdf

Eosinophil Ultrastructure: Atlas of Eosinophil Cell Biology and Pathology entirely focuses on eosinophils and their functional roles in inflammation, host defense, and normal homeostatic activities. The book explores the ultrastructure of human eosinophils, highlighting biological processes observed under normal, experimental, and pathological conditions. Created to fill a void in the eosinophil literature, the book includes an extensive array of electron microscopic images that illustrate the diversity of eosinophil morphology. While the atlas is a learning and teaching tool, it is mainly a helpful resource for researchers to identify distinguishing features and structural changes that arise during studies of human eosinophils. The book also covers the ultrastructure of mouse eosinophils under normal and activation conditions and in the context of representative diseases. Gives guidelines to understand the human eosinophils in studies focused on structural biology, cellular immunology, innate and adaptive immunity, immune responses to pathogens, immunopathology, and inflammatory responses Provides a core of essential knowledge to identify both immature and mature eosinophils Comprises a representative compilation of the eosinophil ultrastructure during biological processes, such as activation and degranulation, mostly under experimental conditions Highlights eosinophil biological processes found in vivo during human diseases, thus providing a link between basic science and clinical aspects Helps identify distinguishing features and structural changes that arise during studies of human eosinophils after isolation from body fluids, while in cultures, or biopsies Explains the ultrastructural organization of mature and immature mouse eosinophils, highlighting the similarities/differences between them and human eosinophils

Author : James J. Lee,Helene F. Rosenberg
Publisher : Academic Press
Page : 679 pages
File Size : 44,5 Mb
Release : 2012-11-02
Category : Health & Fitness
ISBN : 9780123943859

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Eosinophils in Health and Disease by James J. Lee,Helene F. Rosenberg Pdf

Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance.

Author : James J. Lee,Helene F. Rosenberg
Publisher : Elsevier
Page : 679 pages
File Size : 53,5 Mb
Release : 2012-12-31
Category : Medical
ISBN : 9780123946072

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Eosinophils in Health and Disease by James J. Lee,Helene F. Rosenberg Pdf

Written and edited by leaders in the field, Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance. Despite an explosion of discovery in this area over the last decade, this is the only up-to-date resource on eosinophils and eosinophilia exists. This full-color volume provides an essential collection of world class information that is a must-have for any immunologist’s workbench or bookshelf. The only updated, comprehensive source of information on eosinophils on the market Written by over 80 leaders in the field Holistic view of the subject, including basic science, disease-specific chapters, therapeutic options and emerging areas of research

Author : Ann M. Dvorak
Publisher : Karger Medical and Scientific Publishers
Page : 377 pages
File Size : 54,9 Mb
Release : 2005-01-01
Category : Medical
ISBN : 9783805578646

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Ultrastructure of Mast Cells and Basophils by Ann M. Dvorak Pdf

In this book, the author reviews the ultrastructural studies of basophils and mast cells performed since the publication of an earlier monograph in 1991. These studies include the use of ultrastructural rules that allow identification of basophils and mast cells in new circumstances. Including more than 180 excellent micrographs, this book will be of interest to basic scientists in immunology, cell biology, secretion and angiogenesis research, and histochemistry. As mast cells and basophils play a crucial role in various diseases, it will be essential reading for allergists, immunologists, dermatologists, hematologists, gastroenterologists, rheumatologists, neurologists, pathologists, pulmonologists, and cardiologists.

Author : Florence E. Roufosse,Mats W. Johansson
Publisher : Frontiers Media SA
Page : 279 pages
File Size : 40,9 Mb
Release : 2018-12-06
Category : Electronic
ISBN : 9782889456246

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Pathogenic Advances and Therapeutic Perspectives for Eosinophilic Inflammation by Florence E. Roufosse,Mats W. Johansson Pdf

With the recent approval of the first eosinophil-depleting therapeutic agents targeting the IL-5 pathway for treatment of severe eosinophilic asthma, eosinophils and eosinophilic disorders are in the limelight. Indeed, setbacks during clinical development of these compounds have revealed how much remains to be known about eosinophil biology in vivo, and have nurtured profuse research both on basic eosinophil biology and on pathogenic disease mechanisms, in order to better delineate the most meaningful targets for innovative therapeutic strategies. On one hand, variable degrees of eosinophil depletion observed in some compartments during IL-5-targeted treatment indicate that certain eosinophil subsets may not rely on this cytokine and/or that other important pro-eosinophilic mediators and signaling pathways are operative in vivo. On the other hand, it is increasingly clear that disorders involving eosinophils such as asthma are the final outcome of complex interactions between diverse cell types and mediators, beyond eosinophils and IL-5. These include type 2 helper T (Th2) cells and innate lymphoid cells, mast cells, and a variety of factors that either activate eosinophils or are released by them. Although a considerable amount of research has focused on asthma because it is a common condition and because management of severe asthma remains a major challenge, several rare eosinophilic disorders with more homogenous features have proven to be extremely useful models to reach a better understanding of the involvement of eosinophils in tissue damage and dysfunction, and of the micro-environmental interactions operating within the complex network of eosinophilic inflammation. Unraveling this interplay has resulted in advances in the development of molecular tools to detect disease subsets and to monitor therapeutic responses, and in identification of promising new therapeutic targets. This Research Topic dedicated to eosinophilic conditions covers aspects of the biology of eosinophils and closely related cells of particular relevance for drug development, reports on translational research investigating pathogenic mechanisms of specific eosinophilic disorders in humans that will likely result in significant changes in the way patients are managed, and presents an overview of the current advancement of targeted drug development for these conditions, with a special focus on asthma.

Author : Norman F. Cheville
Publisher : John Wiley & Sons
Page : 997 pages
File Size : 51,6 Mb
Release : 2009-06-30
Category : Medical
ISBN : 9780813803302

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Ultrastructural Pathology by Norman F. Cheville Pdf

Ultrastructural Pathology

Author : Gerald J. Gleich
Publisher : CRC Press
Page : 527 pages
File Size : 40,9 Mb
Release : 2019-08-16
Category : Medical
ISBN : 9781000715750

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Eosinophils in Allergy and Inflammation by Gerald J. Gleich Pdf

This work presents the proceedings of a conference held at Adare Manor, County Limerick, Ireland. It provides an updated, in-depth review of the biological role of eosinophils in allergic diseases, summarizing basic knowledge of these unique cationic proteins. The book features an annotated discussion of the conference's post-presentation question-and-answer session.

Author : Anonim
Publisher : Unknown
Page : 1428 pages
File Size : 55,6 Mb
Release : 1990
Category : Medicine
ISBN : OSU:32436011073820

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Cumulated Index Medicus by Anonim Pdf

Author : J. Robin Harris
Publisher : Springer Science & Business Media
Page : 363 pages
File Size : 53,5 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9781475795318

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Megakaryocytes, Platelets, Macrophages, and Eosinophils by J. Robin Harris Pdf

Blood Cell Biochemistry was initially conceived as part of the Plenum series Subcellular Biochemistry, from which it has developed into a separate series. The present volume is devoted primarily to contributions on megakaryocytes and platelets and, to a lesser extent, to macrophages and eosinophils. The book does not attempt a rigorous or total coverage of the particular topics; it represents the areas of current scientific activity and interest that were selected by the editor at the commencement of this project. In general, the approach has been similar to that adopted for Volume 1 of the series (Erythroid Cells); the same approach will be followed subsequently in Volume 3 (Lymphocytes and Granulocytes). This book opens with a developmentally oriented chapter by Janine Breton-Gorius on megakaryocyte maturation and platelet release in normal conditions, which serves to set the scene ultrastructurally for much of the data that follow. The biosynthesis and process ing of platelet glycoproteins in megakaryocytes is dealt with by Alain Duperray and his colleagues, and thereby provides an in-depth biochemical survey of the megakaryocyte. The applications and strengths of crossed immunoelectrophoresis for the study of platelet membrane proteins is then covered by Simon Karpatkin, and a detailed account of the heredity disorders of platelet function is provided by Francine Rendu and Evelyne Dupuy.

Author : Brian Eyden,S. Sankar Banerjee,Yongxin Ru,Paweł Liberski
Publisher : Springer Science & Business Media
Page : 692 pages
File Size : 53,8 Mb
Release : 2014-02-12
Category : Medical
ISBN : 9783642391682

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The Ultrastructure of Human Tumours by Brian Eyden,S. Sankar Banerjee,Yongxin Ru,Paweł Liberski Pdf

The Ultrastructure of Human Tumours: Applications in Diagnosis and Research describes the core features as seen by transmission electron microscopy, defining the different types of cellular differentiation in tumours; this is relevant for tumour nomenclature and diagnosis, which, in turn, are important for tumour pathologists in their collaboration with oncologists for the treatment of cancer patients. The book is divided into 8 chapters. Following an introduction on technique and procedure, there are chapters on epithelial tumours, melanocytic lesions, soft-tissue and related tumours, lymphoma and leukaemia, CNS neoplasms and neuroendocrine and neuronal tumours. Each chapter includes an introductory text that puts the ultrastructural features in the context of classical pathology. The book includes many new findings and interpretations from well-known tumours, as well as ultrastructural information on several newly described tumour entities not dealt with in existing tumour ultrastructure monographs. The book will especially be of value to tumour pathologists who need to solve problem cases with the aid of electron microscopy, but also to cancer research and tissue engineering scientists working to develop anti-cancer and stem-cell-based therapies. However, even those without access to electron microscopy may also benefit from this book, since many of the images provide an ‘explanation’ of the appearances of cells, tissues and tumours familiar to pathologists and scientists from light microscopy. In this respect, it is hoped that this book will stimulate the wider use of electron microscopy in pathology. The book is comprehensively referenced, 680 pages long and lavishly illustrated with 757 figures. Dr. Brian Eyden is Consultant Clinical Scientist and Dr. S. Sankar Banerjee Consultant Histopathologist in the Department of Histopathology, Christie NHS Foundation Trust, Manchester, UK; Dr. Yongxin Ru is Director of the Department of Electron Microscopy, Institute of Hematology and Blood Diseases Hospital, Tianjin, China; Paweł Liberski is Professor in the Department of Molecular Pathology and Neuropathology, Medical University Łódź, Poland.

Author : Shigeharu Ueki,Praveen Akuthota,Josiane Sabbadini Neves
Publisher : Frontiers Media SA
Page : 138 pages
File Size : 48,7 Mb
Release : 2019-12-04
Category : Electronic
ISBN : 9782889631797

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Severe Eosinophilic Disorders: Mechanisms and Clinical Management by Shigeharu Ueki,Praveen Akuthota,Josiane Sabbadini Neves Pdf

Author : Judah A. Denburg
Publisher : Springer Science & Business Media
Page : 589 pages
File Size : 51,5 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781475727760

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Allergy and Allergic Diseases by Judah A. Denburg Pdf

Allergy and Allergic Diseases has been organized to provide an up-to-date, clinically relevant compilation of one of the most exciting areas of investigation in medicine today-allergic disease, especially as it pertains to the skin, airways, and bowel. With the dramatic rise in the incidence of various allergic disorders worldwide, and the coming of age of the discipline of Clinical Immunology and Allergy, the interface between basic and clinical science in this arena demands highlighting in this comprehensive new syn thesis.1t is with the hope of filling this evident need that Allergy and Allergic Diseases: The New Mechanisms and Therapeutics has been put together. The book's content is divided into both basic and clinical sections, with emphasis on various components of the immune and inflammatory response as they relate to the development of allergic disease. Topics span the range from molecular biology to clinical symptomatology, with an effort to make this of interest to as broad a constituency as possible. This book will therefore be of substantial interest to specialists in Clinical Immunology and Allergy, scientists studying the cellular and molecular biology of in flammation and immunity, as well as internists, teachers, developers of medical school curricula, and members of industry focused on drug discovery and therapeutics. Indeed, a separate section has been added to deal with some specific issues in this latter field.

Author : Terry W. Campbell,Christine K. Ellis
Publisher : John Wiley & Sons
Page : 562 pages
File Size : 55,7 Mb
Release : 2013-07-03
Category : Medical
ISBN : 9781118710661

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Avian and Exotic Animal Hematology and Cytology by Terry W. Campbell,Christine K. Ellis Pdf

This is the long-awaited revision and expansion of Avian Hematology and Cytology, 2nd Edition. This new book builds on the avian foundation of Campbell’s earlier work and has grown to include coverage of several other important exotic animal groups including small mammals, reptiles, fish, and amphibians. This is the must-have hematologic and cytologic reference for all veterinarians and researchers working with avian and exotic animals.

Author : J. C. Cawley,Frank George James Hayhoe
Publisher : Unknown
Page : 296 pages
File Size : 41,5 Mb
Release : 1973
Category : Blood cells
ISBN : UOM:39015003772764

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Ultrastructure of Haemic Cells by J. C. Cawley,Frank George James Hayhoe Pdf

Author : Anonim
Publisher : Academic Press
Page : 335 pages
File Size : 52,8 Mb
Release : 1986-10-16
Category : Medical
ISBN : 0080578152

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Advances in Immunology by Anonim Pdf

Advances in Immunology