Epigenetics And Metabolomics

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Epigenetics and Metabolomics

Paban K. Agrawala,Poonam Rana
Epigenetics and Metabolomics Book PDF

Author : Paban K. Agrawala,Poonam Rana
Publisher : Elsevier
Page : 478 pages
File Size : 50,7 Mb
Release : 2021-08-25
Category : Medical
ISBN : 9780323856539

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Epigenetics and Metabolomics by Paban K. Agrawala,Poonam Rana Pdf

Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare. Offers a synthesized discussion of epigenetic regulation of metabolic activity and systems-based approaches to power new research Discusses epigenetic control of metabolic pathways and possible therapeutic targets for cancer, neurodegenerative, and neuroendocrine diseases, among others Provides guidance in epigenomics and metabolomic research methodology

Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods

Debasis Bagchi,Anand Swaroop,Manashi Bagchi
Genomics Proteomics and Metabolomics in Nutraceuticals and Functional Foods Book PDF

Author : Debasis Bagchi,Anand Swaroop,Manashi Bagchi
Publisher : John Wiley & Sons
Page : 685 pages
File Size : 48,8 Mb
Release : 2015-10-12
Category : Technology & Engineering
ISBN : 9781118930427

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Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods by Debasis Bagchi,Anand Swaroop,Manashi Bagchi Pdf

Functional foods and nutraceuticals have received considerable interest in the past decade largely due to increasing consumer awareness of the health benefits associated with food. Diet in human health is no longer a matter of simple nutrition: consumers are more proactive and increasingly interested in the health benefits of functional foods and their role in the prevention of illness and chronic conditions. This, combined with an aging population that focuses not only on longevity but also quality of life, has created a market for functional foods and nutraceuticals. A fully updated and revised second edition, Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods reflects the recent upsurge in "omics" technologies and features 48 chapters that cover topics including genomics, proteomics, metabolomics, epigenetics, peptidomics, nutrigenomics and human health, transcriptomics, nutriethics and nanotechnology. This cutting-edge volume, written by a panel of experts from around the globe reviews the latest developments in the field with an emphasis on the application of these novel technologies to functional foods and nutraceuticals.

Genetics Meets Metabolomics

Karsten Suhre
Genetics Meets Metabolomics Book PDF

Author : Karsten Suhre
Publisher : Springer Science & Business Media
Page : 328 pages
File Size : 52,8 Mb
Release : 2012-06-15
Category : Medical
ISBN : 9781461416890

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Genetics Meets Metabolomics by Karsten Suhre Pdf

This book is written by leading researchers in the fields about the intersection of genetics and metabolomics which can lead to more comprehensive studies of inborn variation of metabolism.

Personalized Medicine in Anesthesia, Pain and Perioperative Medicine

Ali Dabbagh
Personalized Medicine in Anesthesia Pain and Perioperative Medicine Book PDF

Author : Ali Dabbagh
Publisher : Springer Nature
Page : 401 pages
File Size : 52,5 Mb
Release : 2020-09-21
Category : Medical
ISBN : 9783030535254

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Personalized Medicine in Anesthesia, Pain and Perioperative Medicine by Ali Dabbagh Pdf

This book discusses the current and future impact of cellular and molecular medicine (CMM) on anesthesiology and perioperative medicine. It covers the topic from a translational perspective and describes the relevance of CMM to daily clinical practice. Taking a bench-to-bedside approach, chapters examine topics including perioperative acute and chronic management, perioperative organ protection, and novel pharmaceuticals. Personalized Medicine in Anesthesia, Pain and Perioperative Medicine is aimed at anesthesiologists and pain physicians, and will also be of interest to pharmacists and those working in cellular and molecular medicine.

Environmental Epigenetics

L. Joseph Su,Tung-chin Chiang
Environmental Epigenetics Book PDF

Author : L. Joseph Su,Tung-chin Chiang
Publisher : Springer
Page : 321 pages
File Size : 48,8 Mb
Release : 2015-05-18
Category : Medical
ISBN : 9781447166788

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Environmental Epigenetics by L. Joseph Su,Tung-chin Chiang Pdf

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Toxicology and Epigenetics

Saura C. Sahu
Toxicology and Epigenetics Book PDF

Author : Saura C. Sahu
Publisher : John Wiley & Sons
Page : 822 pages
File Size : 48,8 Mb
Release : 2012-08-23
Category : Science
ISBN : 9781118349069

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Toxicology and Epigenetics by Saura C. Sahu Pdf

Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. An international team of experts consider the interplay between epigenetics and toxicology in a number of areas, including environmental, nutritional, pharmacological, and computational toxicology, nanomaterials, proteomics and metabolomics, and cancer research. Topics covered include: environment, epigenetics and diseases DNA methylation and toxicogenomics chromatin at the intersection of disease and therapy epigenomic actions of environmental arsenicals environment, epigenetics and cardiovascular health toxicology, epigenetics and autoimmunity ocular epigenomics: potential sites of environmental impact in development and disease nuclear RNA silencing and related phenomena in animals epigenomics – impact for drug safety sciences methods of global epigenomic profiling transcriptomics: applications in epigenetic toxicology Toxicology and Epigenetics is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors and regulators in academia, industry and government.

Evolution of Translational Omics

Institute of Medicine,Board on Health Sciences Policy,Board on Health Care Services,Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials
Evolution of Translational Omics Book PDF

Author : Institute of Medicine,Board on Health Sciences Policy,Board on Health Care Services,Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials
Publisher : National Academies Press
Page : 354 pages
File Size : 50,8 Mb
Release : 2012-09-13
Category : Science
ISBN : 9780309224185

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Evolution of Translational Omics by Institute of Medicine,Board on Health Sciences Policy,Board on Health Care Services,Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials Pdf

Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Plant Metabolomics

Kazuki Saito,Richard A. Dixon,Lothar Willmitzer
Plant Metabolomics Book PDF

Author : Kazuki Saito,Richard A. Dixon,Lothar Willmitzer
Publisher : Springer Science & Business Media
Page : 351 pages
File Size : 42,8 Mb
Release : 2006-06-29
Category : Science
ISBN : 9783540297826

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Plant Metabolomics by Kazuki Saito,Richard A. Dixon,Lothar Willmitzer Pdf

Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.

Integrative Preventive Medicine

Richard H. Carmona,Mark Liponis
Integrative Preventive Medicine Book PDF

Author : Richard H. Carmona,Mark Liponis
Publisher : Oxford University Press
Page : 585 pages
File Size : 51,6 Mb
Release : 2017-12-12
Category : Medical
ISBN : 9780190241254

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Integrative Preventive Medicine by Richard H. Carmona,Mark Liponis Pdf

For most clinicians, the science and evidence for many integrative therapies is largely unknown or considered suspect. Most physicians don't have time to learn integrative approaches and aren't sure what to recommend or which approaches have merit or improved outcomes. Here, clinicians have easy access to the best practices in integrative medicine and expectations for outcomes

Comprehensive Foodomics

Anonim
Comprehensive Foodomics Book PDF

Author : Anonim
Publisher : Elsevier
Page : 2444 pages
File Size : 44,6 Mb
Release : 2020-11-12
Category : Science
ISBN : 9780128163962

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Comprehensive Foodomics by Anonim Pdf

Comprehensive Foodomics, Three Volume Set offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing all this information together in an easily navigable reference, food scientists and nutritionists in both academia and industry will find it the perfect, modern day compendium for frequent reference. List of sections and Section Editors: Genomics - Olivia McAuliffe, Dept of Food Biosciences, Moorepark, Fermoy, Co. Cork, Ireland Epigenetics & Noncoding RNA - Juan Cui, Department of Computer Science & Engineering, University of Nebraska-Lincoln, Lincoln, NE Transcriptomics - Robert Henry, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, Australia Proteomics - Jens Brockmeyer, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Germany Metabolomics - Philippe Schmitt-Kopplin, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany Omics data treatment, System Biology and Foodomics - Carlos Leon Canseco, Visiting Professor, Biomedical Engineering, Universidad Carlos III de Madrid Green Foodomics - Elena Ibanez, Foodomics Lab, CIAL, CSIC, Madrid, Spain Food safety and Foodomics - Djuro Josic, Professor Medicine (Research) Warren Alpert Medical School, Brown University, Providence, RI, USA & Sandra Kraljevic Pavelic, University of Rijeka, Department of Biotechnology, Rijeka, Croatia Food Quality, Traceability and Foodomics - Daniel Cozzolino, Centre for Nutrition and Food Sciences, The University of Queensland, Queensland, Australia Food Bioactivity, Health and Foodomics - Miguel Herrero, Department of Bioactivity and Food Analysis, Foodomics Lab, CIAL, CSIC, Madrid, Spain Brings all relevant foodomics information together in one place, offering readers a ‘one-stop,’ comprehensive resource for access to a wealth of information Includes articles written by academics and practitioners from various fields and regions Provides an ideal resource for students, researchers and professionals who need to find relevant information quickly and easily Includes content from high quality authors from across the globe

Role of Epigenetic Modifications on Diet-Induced Metabolic Diseases

Anna Alisi,Manlio Vinciguerra,Andrea Masotti
Role of Epigenetic Modifications on Diet Induced Metabolic Diseases Book PDF

Author : Anna Alisi,Manlio Vinciguerra,Andrea Masotti
Publisher : Frontiers Media SA
Page : 180 pages
File Size : 49,9 Mb
Release : 2020-12-02
Category : Science
ISBN : 9782889661480

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Role of Epigenetic Modifications on Diet-Induced Metabolic Diseases by Anna Alisi,Manlio Vinciguerra,Andrea Masotti Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Precision Nutrition and Metabolic Syndrome Management

Alfredo J. Martínez,Angeles M. Zulet
Precision Nutrition and Metabolic Syndrome Management Book PDF

Author : Alfredo J. Martínez,Angeles M. Zulet
Publisher : MDPI
Page : 223 pages
File Size : 50,7 Mb
Release : 2018-08-21
Category : Electronic
ISBN : 9783038428596

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Precision Nutrition and Metabolic Syndrome Management by Alfredo J. Martínez,Angeles M. Zulet Pdf

This book is a printed edition of the Special Issue "Precision Nutrition and Metabolic Syndrome Management" that was published in Nutrients

Epigenetics in Human Disease

Trygve O Tollefsbol
Epigenetics in Human Disease Book PDF

Author : Trygve O Tollefsbol
Publisher : Elsevier
Page : 1362 pages
File Size : 43,8 Mb
Release : 2023-10-09
Category : Medical
ISBN : 9780443218125

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Epigenetics in Human Disease by Trygve O Tollefsbol Pdf

Epigenetics in Human Disease, Third Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. From molecular mechanisms and epigenetic technology to clinical translation of recent research, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders, with an emphasis throughout on understanding and application of key concepts in new research and clinical practice. Fully revised and up-to-date, this Third Edition discusses topics of current interest in epigenetic disease research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, microRNA in cancer, epigenetic approaches to control obesity, epigenetics and airway disease, and epigenetics in cardiovascular disease. Further sections explore online epigenetic tools and datasets; early-life programming of epigenetics in age-related diseases; the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer’s disease, respiratory diseases, and many other human maladies. In addition, each chapter now includes chapter summaries, definitions, and vibrant imagery and figures to reinforce understanding, as well as step-by-step methods and disease research case studies. Includes contributions from leading international investigators involved in translational epigenetic research and therapeutic applications Integrates methods and applications with fundamental chapters on epigenetics in human disease, along with an evaluation of recent clinical breakthroughs Presents side-by-side coverage of the basis of epigenetic diseases and treatment pathways Each chapter updated to include summaries, definitions, and vibrant imagery and figures to reinforce understanding Features step-by-step methods and disease research case studies to put book concepts into practice

Neuropsychiatric Disorders and Epigenetics

Jacob Peedicayil,Dennis R. Grayson
Neuropsychiatric Disorders and Epigenetics Book PDF

Author : Jacob Peedicayil,Dennis R. Grayson
Publisher : Elsevier
Page : 418 pages
File Size : 44,6 Mb
Release : 2023-09-29
Category : Science
ISBN : 9780443185175

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Neuropsychiatric Disorders and Epigenetics by Jacob Peedicayil,Dennis R. Grayson Pdf

Neuropsychiatric Disorders and Epigenetics, Second Edition is a comprehensive reference on the epigenetic basis of common neuropsychiatric disorders. The volume is organized into chapters covering individual neuropsychiatric disorders, from addiction to anxiety and autism spectrum disorders, and is contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of associated epigenetic mechanisms, including DNA modification, histone post-translational modification, chromatin organization, and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects of environmental stimuli on epigenetic states is particularly relevant to disease. This new edition has been fully updated to reflect recent research advances enabled by genomic technologies, as well as therapeutic interventions for previously unmanageable disorders. Several new chapters have been added on disorders or approaches not considered in the earlier edition, including epigenetics and anxiety disorders, epigenetics and neuroimaging in neuropsychiatric disorders, genome-wide approaches to epigenetic research, and the epigenetics of spinal muscular atrophy. By helping to define epigenetics as a key player in neuropsychiatric disorders, this volume empowers new research, clinical translation, and pharmacological advances, and highlights promising directions for ongoing investigation. Analyzes the effects of environmental stimuli on epigenetic states that correlate with neuropsychiatric disease induction Reviews the epigenetic basis for common neuropsychiatric disorders, thereby guiding translational therapies for clinicians and mechanistic studies for scientists Features extensive use of diagrams, illustrations, tables, and graphical abstracts for each section to reinforce understanding Includes chapter contributions from leading global experts

Epigenetics in Precision Medicine

Jose Luis Garcia-Gimenez
Epigenetics in Precision Medicine Book PDF

Author : Jose Luis Garcia-Gimenez
Publisher : Elsevier
Page : 616 pages
File Size : 51,8 Mb
Release : 2021-11-12
Category : Medical
ISBN : 9780323858052

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Epigenetics in Precision Medicine by Jose Luis Garcia-Gimenez Pdf

In recent years, knowledge of epigenetic mechanisms underlying disease onset and progression has proven crucial for the development of novel early diagnosis and prognosis biomarkers for patient stratification and precision medicine. Epigenetics in Precision Medicine, a new volume in the Translational Epigenetics series, provides a thorough discussion and overview of current developments in clinical epigenetics with special emphasis on epigenetic biomarkers that can be used for clinical diagnosis, prognosis, patient stratification, and treatment monitoring. Disease types discussed include cancer, metabolic disorders, neurodegenerative diseases, bone disease, and immune-related disorders. The book examines the challenges of advancing epigenetics research and translating findings to the clinic and drug discovery in each of these areas, as well as current solutions; chapter authors discuss how to leverage epigenomic technologies, applications, and tools, such as next-generation sequencing, to discover new epigenetic biomarkers in disease and drug studies. Epigenetics in Precision Medicine focuses on complex epigenetic mechanisms in several pathologies, and explores how epigenetics can power the advance of precision medicine, not only by improving in vitro diagnostic and prognostic tools, but by providing new therapeutic approaches to treat human disease. Provides a thorough grounding in epigenetics-driven precision medicine, with emphasis on developing and implementing early diagnosis and prognosis biomarkers, and supporting patient stratification Empowers researchers and clinicians to incorporate epigenetics in new disease research, drug discovery, and clinical practice Features chapter contributions from international leaders in the field