Essential Hypertension

Author : Flávio Danni Fuchs
Publisher : Springer
Page : 151 pages
File Size : 42,8 Mb
Release : 2017-11-20
Category : Medical
ISBN : 9783319632728

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Essentials of Hypertension by Flávio Danni Fuchs Pdf

The main purpose of this book is to select and present the most essential information about hypertension. It aims to select all the more relevant data to guide the attitudes to prevent, diagnose, and treat hypertension. Hypertension accounts for more than 50% of deaths from stroke and ischemic heart disease worldwide. New blood pressure (BP) diagnostic thresholds for hypertension were released, which were set at 130/80 mmHg. As a consequence, millions of individuals in the world will be diagnosed as hypertensive, recognizing that they are at greater risk of presenting a CV event. Prevention and control of high BP will become the main focus for reducing the burden of CV disease, requiring a changing of cultural beliefs in some way similar to what happened in the last century with smoking. Strategies for prevention of the rising of BP with age, and the BP reduction in individuals already with high levels, are more complex than those related to smoking control. These strategies involve solid evidence to be implemented in populations. The extensive scientific literature dealing with hypertension and BP regulation is among the top dedicated to a single disease. The chapters and contents follow the clinical reasoning pathways. The characterization of the risks of high blood pressure is presented in the first chapter, discussing the evidence that led to changes in diagnostic thresholds and to the recommendations for maintaining BP within these limits in populations. Reasons for BP rising with age will follow, identifying the causes that must be fought to preventing the incidence of hypertension. Diagnosis of hypertension deserves a special chapter. The final chapter presents the fundamentals to select drug and non-drug therapies indicated in the prevention and controlling of high blood pressure.

Author : J. M. Cruickshank
Publisher : PMPH-USA
Page : 474 pages
File Size : 53,9 Mb
Release : 2012-12
Category : Blood pressure
ISBN : 9781607951681

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Essential Hypertension by J. M. Cruickshank Pdf

Essential (primary) Hypertension is the most current, concise, and practical step-by-step guide to the diagnosis, evaluation, and treatment of hypertension. This book provides all the knowledge base needed to identify and manage patients with Hypertension. 60% of those over the age of 60 suffer from Hypertension, a disease which affects hundreds of millions of individuals worldwide. This book guides the reader to understanding, proper diagnosis treatment.

Author : George S. Stergiou,Gianfranco Parati,Giuseppe Mancia
Publisher : Springer Nature
Page : 174 pages
File Size : 47,5 Mb
Release : 2019-10-31
Category : Medical
ISBN : 9783030230654

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Home Blood Pressure Monitoring by George S. Stergiou,Gianfranco Parati,Giuseppe Mancia Pdf

Hypertension remains a leading cause of disability and death worldwide. Self-monitoring of blood pressure by patients at home is currently recommended as a valuable tool for the diagnosis and management of hypertension. Unfortunately, in clinical practice, home blood pressure monitoring is often inadequately implemented, mostly due to the use of inaccurate devices and inappropriate methodologies. Thus, the potential of the method to improve the management of hypertension and cardiovascular disease prevention has not yet been exhausted. This volume presents the available evidence on home blood pressure monitoring, discusses its strengths and limitations, and presents strategies for its optimal implementation in clinical practice. Written by distinguished international experts, it offers a complete source of information and guide for practitioners and researchers dealing with the management of hypertension.

Author : Paul I. Korner
Publisher : Oxford University Press
Page : 720 pages
File Size : 55,6 Mb
Release : 2007-05-11
Category : Medical
ISBN : 9780190282547

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Essential Hypertension and Its Causes by Paul I. Korner Pdf

This new account of the pathogenesis of essential hypertension (EH) represents a detailed analysis of the main components of the circulatory control system. The latter's properties resemble those of man-made adaptive control systems in which regulatory parameters are altered when operating conditions exceed certain limits, often through neural mechanisms. Inheritance of EH depends on both genes and environment. The high blood pressure (BP) genes have not yet been definitively identified, whilst the main environmental causes are mental stress, high dietary salt intake and obesity. EH occurs as two major syndromes, each initiated by chronic stress: 1) Stress-and-salt related EH, and 2) Hypertensive obesity. Stress is perceived by the cortex, from which increased dopaminergic (DA) neuron activity stimulates the hypothalamic defense area, raising sympathetic neural activity (SNA) and BP. Normally these subside quickly when the stress is over, but in those susceptible to EH the DA synapses become sensitized so that the defense response is evoked by ever lower levels of stress. Sensitization is common in memory circuits, but not in autonomic neurons, so that this property in EH may be genetically determined. Stress-related hypertension increases hypothalamic responsiveness to high salt, resulting in further rises in SNA and BP. Later, non-neural functional changes (e.g. reduction in nitric oxide) and the structural remodeling of resistance vessels further enhance the vasoconstriction. In contrast, in those developing hypertensive obesity food consumption is excessive, which transiently alleviates stress-related anxiety. The brain ignores the leptin-mediated signals that normally curb appetite, contrasting with normal energy regulation in SSR-EH. In hypertensive obesity, the SNA pattern is similar to that in SSR-EH, but vasoconstriction is masked by vasodilatation and fluid retention due to hyperinsulinemia. This syndrome is a volume overload hypertension, where high cardiac output, renal impairment and other non-neural factors contribute to the elevation of BP. Other topics include the role of various transmitters in autonomic regulation; the place of baroreflexes in the intact organism; why exercise training lowers resting BP; obstructive sleep apnea; non-pharmacological and drug treatment of EH; the role of the kidney in EH and in different types of renal hypertension and the pathogenesis of the Japanese spontaneously hypertensive rat, which provides a valuable animal model for EH. The work suggests that physiological systems analysis in a complex disorder like EH is a valuable tool for using the great advances in molecular biology to best advantage.

Author : K. D. Bock,P. Cottier
Publisher : Springer-Verlag
Page : 423 pages
File Size : 41,8 Mb
Release : 2013-03-08
Category : Medical
ISBN : 9783642498992

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Essential Hypertension by K. D. Bock,P. Cottier Pdf

Author : Sir George White Pickering
Publisher : Unknown
Page : 168 pages
File Size : 52,9 Mb
Release : 1961
Category : Hypertension
ISBN : OSU:32436000046951

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The Nature of Essential Hypertension by Sir George White Pickering Pdf

Author : Joseph Flynn,Julie R. Ingelfinger,Ronald J. Portman
Publisher : Springer Science & Business Media
Page : 600 pages
File Size : 50,8 Mb
Release : 2013-06-26
Category : Medical
ISBN : 9781627034906

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Pediatric Hypertension by Joseph Flynn,Julie R. Ingelfinger,Ronald J. Portman Pdf

The field of pediatric hypertension has undergone important changes in the time since the second edition of Pediatric Hypertension published. Much new information on hypertension in the young has become available. Previous chapters have been fully revised and new chapters have been added to cover important topics of recent interest such as consensus recommendations, the prevalence of hypertension in the young due to the obesity epidemic, studies of antihypertensive agents, and ambulatory blood pressure monitoring. Pediatric Hypertension, Third Edition is a comprehensive volume featuring 38 chapters covering the breadth of the current knowledge. It is divided into four sections: Regulation of Blood Pressure in Children; Assessment of Blood Pressure in Children: Measurement, Normative Data, Epidemiology; and Hypertension in Children: Predictors, Risk Factors, and Special Populations; Evaluation and Management of Pediatric Hypertension. Filled with the most up-to-date information, Pediatric Hypertension, Third Edition is an invaluable resource for clinicians and researchers interested in childhood hypertension.

Author : Madhu Khullar
Publisher : BoD – Books on Demand
Page : 250 pages
File Size : 50,5 Mb
Release : 2012-03-09
Category : Medical
ISBN : 9789535102823

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Genetics and Pathophysiology of Essential Hypertension by Madhu Khullar Pdf

This book, authored by renowned researchers in the field of Hypertension Research, details the state of the art knowledge in genetics, genomics and pathophysiology of Essential hypertension, specifically the genetic determinants of hypertension and role of gene variants in response to anti-hypertensive therapy. Two chapters describe mitochondrial mutations in Essential hypertension and in hypertension associated Left ventricular hypertrophy, one chapter reviews in detail the global gene expression in hypertension, and an up to date treatise on pathophysiology of resistant hypertension is detailed in another chapter. Other topics included in the book are end organ damage, baroreceptor sensitivity and role of music therapy in essential hypertension.

Author : Kazuomi Kario
Publisher : John Wiley & Sons
Page : 152 pages
File Size : 53,9 Mb
Release : 2015-05-06
Category : Medical
ISBN : 9781119087243

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Essential Manual of 24 Hour Blood Pressure Management by Kazuomi Kario Pdf

It is well known that cardiovascular events occur more frequently in the morning as blood pressure (BP) levels have been shown to increase during the period from night to early morning. In recent years, clinical research using ambulatory blood pressure monitoring (ABPM) or home BP monitoring has clarified that morning BP and BP surge are more closely related to the cardiovascular risk than clinical BP. This practical manual from field leading expert, Dr. Kazuomi Kario, reviews recent evidence on morning and nocturnal hypertension and the IT technologies physicians can use to support patients in home monitoring BP. Guidance on management via antihypertensive drugs is also discussed and with the aim of promoting perfect 24 hour BP control.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 45,8 Mb
Release : 1944
Category : Electronic
ISBN : OCLC:1004839666

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Essential Hypertension by Anonim Pdf

Author : Kyuzo Aoki
Publisher : Springer Science & Business Media
Page : 404 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9784431680901

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Essential Hypertension 2 by Kyuzo Aoki Pdf

The First International Symposium on Mechanism and Treatment in Essential Hypertension was held on October 23 and 24, 1985 in Nagoya. The Second International Symposium, which was held on May 30,31, and June 1, 1988 in Nagoya, was a success thanks to the endeavors of all the participants. These symposiums were made possible by the generous support of the city of Nagoya, Aichi Prefec ture, and various contributions. Understanding of the mechanisms of gene (major gene, essential) hypertension is impossible unless we comprehend the physiological properties of arterial smooth muscle. Since Langendorff's discovery of the role of calcium ions in muscle contraction in 1895, we have made immense progress in our knowledge of the role of the calcium ion in the excitation-contraction coupling of the arterial smooth mus cle. Investigation of the molecular mechanisms controlling the cellu lar basis of calcium ion action has been established with the discovery of the calcium binding protein (Ebashi 1963). The participation of the calcium induced calcium mechanism in the contraction of muscle has been directly demonstrated by using chemically skinned smooth muscle fibers (Endo et al. 1977). Methods for intracellular free cal cium contents and calcium channel activity have been developed and contribute to the study of the role of the calcium ion in arterial smooth muscle contractility. Such recent progress promotes study of the basic physiological, biochemical, and molecular properties of the calcium channel, and, in the field of hypertension research, the sodium and potassium channels.

Author : Joseph L. Izzo,Henry Richard Black,Council for High Blood Pressure Research (American Heart Association)
Publisher : Lippincott Williams & Wilkins
Page : 566 pages
File Size : 41,9 Mb
Release : 2003
Category : Medical
ISBN : 0781745098

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Hypertension Primer by Joseph L. Izzo,Henry Richard Black,Council for High Blood Pressure Research (American Heart Association) Pdf

Now in its thoroughly updated Third Edition, the Hypertension Primer is a comprehensive, readable source of state-of-the-art scientific and clinical information on hypertension. The book contains more than 150 short chapters by distinguished experts that cover every aspect of hypertension and its pathogenesis, epidemiology, impact, and management. The chapters are grouped into three well-organized sections--basic science, population science, and clinical management--and each chapter is cross-referenced to other relevant chapters. Each chapter is easily digestible and begins with a bulleted list of key points.

Author : Raffaele Izzo
Publisher : Springer
Page : 89 pages
File Size : 47,8 Mb
Release : 2017-05-15
Category : Medical
ISBN : 9783319560809

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Hypertension and Cardiac Organ Damage by Raffaele Izzo Pdf

This book identifies the key determinants in the management of hypertensive outpatients with Cardiac Target Organ Damage. It sheds light on current international guidelines by directly applying them to six representative clinical cases that reflect situations frequently encountered during clinical routine rather than emergencies or rare occurrences. The book enables cardiologists and angiologists alike to gain an overview of the most frequent cardiac dysfunctions related to hypertension: left atrial enlargement, aortic root dilatation, diastolic dysfunction, systolic dysfunction, left and right ventricular enlargement. Each case is illustrated and analyzed in detail – from family and personal history to treatment and follow-up – providing readers with valuable guidance that will help them to select the best suited diagnostic tool and treatment for each patient.

Author : Franz H. Messerli
Publisher : Springer Science & Business Media
Page : 259 pages
File Size : 43,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461338970

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Kidney in Essential Hypertension by Franz H. Messerli Pdf

The kidney, similar to the heart, plays a three-fold role in essential hypertension. First, it participates in the patho genesis of arterial hypertension. Second, it suffers as a target organ of long-standing hypertension, and third, it experiences the effects of antihypertensive therapy. Perhaps most contested at the present time is the involvement of the kidney in the patho genesis of essential hypertension. More than a century ago, William Osler put forward three basic hypotheses about the "genuine contracted kidney. "l 1. "The hypertrophy can be regarded as an effect to overcome a sort of stop-cock action of the vessels when under the influence of an irritating ingredient in the blood greatly contracted and increased the peripheral resistance. " Clearly this hypothesis of an "irritating ingredient" is perhaps the most convincing nowadays, and numerous attempts have been made to identify a specific vasoconstrictive agent in the blood in essential hypertension. 2. "The obliteration of a large number of capillary territories in the kidney materially raised the arterial pressure. An additional factor of dimin ished excretion of water also heightened the pressure within the blood vessel. " Today we know that fluid volume overload in the presence of reduced renal mass seems to be the most likely mechanism accoun ting for renal parenchymal hypertension and, as shown by Guyton's group, for certain forms of experimental hypertension. 3.

Author : Kyuzo Aoki
Publisher : Springer Science & Business Media
Page : 244 pages
File Size : 49,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9784431680482

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Essential Hypertension by Kyuzo Aoki Pdf

This volume contains papers presented at the First International Symposium on Mechanism and Treatment in Essential Hyperten sion, which was held on October 23 and 24, 1985 in Nagoya, Japan. The meeting was an official satellite symposium to the meeting of the Fifth International Symposium on Rats with Spon taneous Hypertension and Related Studies in Kyoto, October 20-22, 1985. The Nagoya symposium was made possible by offi cial grants from the city of Nagoya and Aichi Prefecture and the generous financial support of many companies. The aim of the symposium was to provide a forum for presen tation and discussion of recent advances in the area of essential hypertension, particularly with regard to calcium mechanisms in vasoconstriction and vasodilation in arterial vessels and the func tion of arterial smooth muscle. The role of calcium ions in the function of arterial smooth muscle has attracted a great deal of attention in the last two decades. The mode of action of calcium ions was revealed at the molecular level. The hypertension model of the spontaneously hypertensive rat has been widely utilized for research into the fundamental mechanisms of genetic hyperten sion, stroke, and cardiovascular disease as well as into therapeutic measures. New tools of calcium agonists and antagonists have become available to research into the mechanism, prevention, and treatment of essential hypertension at the molecular, subcellular, and cellular levels of arterial smooth muscle, at the organ level of arterial vessels, as well as at the total systemic level.